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The map label for this gene is yggV [C]

Identifier: 15605763

GI number: 15605763

Start: 122071

End: 122679

Strand: Direct

Name: yggV [C]

Synonym: aq_202

Alternate gene names: 15605763

Gene position: 122071-122679 (Clockwise)

Preceding gene: 15605762

Following gene: 15605764

Centisome position: 7.87

GC content: 43.35

Gene sequence:

>609_bases
ATGAAACTGCTGGTTGCCACCACAAACGAAGGAAAGTACAGGGAGATAAAAGAAATTCTTTCCGAGTATGGTATTGAAGT
ATTAAAACCCGAGGAAAAACTGGAAGTAGAGGAAACGGGTTGTACATTTTTAGAAAACGCATACCTGAAGGCTAGAGCTT
ACTACGAAAGGTACAAAATCCCTGCGCTTGCGGACGACTCCGGTCTTATCGTTGAAGCCATAAGCCCATATCCGGGTGTG
TATTCCAGCAGGTTTTACGACATAGACTTCGGCGGCAGGGAAGAAGTAAGAACGAACAAGGACGAAGCAAACATAAGAAA
ACTTTTAAGGCTTTTGGAAAACACAGAAAACAGGAAGGCAAAATTTGTAGCTTTTATAGTCGTATACGGGGGAAGTTGGG
GAATTTTTGCAGAAGGAGAAGTCAGGGGAGAGATAACGAAAGAGCCGAGGGGAGACAGAGGTTTTGGCTACGACCCCGTT
TTCGTTCCGGAAGGTTATAACAAAACCATGGCTGAACTTTCTCCGGAAGAAAAGAACAAAATATCCCACAGGGGGAGAGC
TTTAAGAAAGCTCGTACATGTACTGAAAAATTGTGAAAAAGCTTTCTGA

Upstream 100 bases:

>100_bases
TGGAGGAGAAGGGTAAAGAAATAGTTCCCGTGGAAGAGGAGGAAAAAGGAACGGAAGAAAGGGAAGGCTTTTTGGAAAGG
TTTAAAAAATTCTTCGGGCT

Downstream 100 bases:

>100_bases
AAAGTTAAGAGCTTACGAAGTTCTAAGGGAAGTCTTCAACGTAATTGCGGTTATCTCCCTGAACAGGTTTAAAAAAACGA
GACACATAGTCTCTCAAGAG

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MKLLVATTNEGKYREIKEILSEYGIEVLKPEEKLEVEETGCTFLENAYLKARAYYERYKIPALADDSGLIVEAISPYPGV
YSSRFYDIDFGGREEVRTNKDEANIRKLLRLLENTENRKAKFVAFIVVYGGSWGIFAEGEVRGEITKEPRGDRGFGYDPV
FVPEGYNKTMAELSPEEKNKISHRGRALRKLVHVLKNCEKAF

Sequences:

>Translated_202_residues
MKLLVATTNEGKYREIKEILSEYGIEVLKPEEKLEVEETGCTFLENAYLKARAYYERYKIPALADDSGLIVEAISPYPGV
YSSRFYDIDFGGREEVRTNKDEANIRKLLRLLENTENRKAKFVAFIVVYGGSWGIFAEGEVRGEITKEPRGDRGFGYDPV
FVPEGYNKTMAELSPEEKNKISHRGRALRKLVHVLKNCEKAF
>Mature_202_residues
MKLLVATTNEGKYREIKEILSEYGIEVLKPEEKLEVEETGCTFLENAYLKARAYYERYKIPALADDSGLIVEAISPYPGV
YSSRFYDIDFGGREEVRTNKDEANIRKLLRLLENTENRKAKFVAFIVVYGGSWGIFAEGEVRGEITKEPRGDRGFGYDPV
FVPEGYNKTMAELSPEEKNKISHRGRALRKLVHVLKNCEKAF

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family

Homologues:

Organism=Escherichia coli, GI1789324, Length=212, Percent_Identity=40.0943396226415, Blast_Score=142, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17556833, Length=196, Percent_Identity=31.1224489795918, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19920712, Length=190, Percent_Identity=33.6842105263158, Blast_Score=78, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NTPA_AQUAE (O66580)

Other databases:

- EMBL:   AE000657
- PIR:   H70318
- RefSeq:   NP_213140.1
- ProteinModelPortal:   O66580
- SMR:   O66580
- GeneID:   1192722
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_202
- NMPDR:   fig|224324.1.peg.155
- HOGENOM:   HBG697237
- OMA:   VYTADWA
- PhylomeDB:   O66580
- ProtClustDB:   PRK14824
- BioCyc:   AAEO224324:AQ_202-MONOMER
- BRENDA:   3.6.1.15
- HAMAP:   MF_01405
- InterPro:   IPR002637
- InterPro:   IPR020922
- PANTHER:   PTHR11067
- TIGRFAMs:   TIGR00042

Pfam domain/function: PF01725 Ham1p_like

EC number: =3.6.1.15

Molecular weight: Translated: 23116; Mature: 23116

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLVATTNEGKYREIKEILSEYGIEVLKPEEKLEVEETGCTFLENAYLKARAYYERYKI
CEEEEEECCCCCHHHHHHHHHHCCCEEECCHHHCCHHHCCCHHHHHHHHHHHHHHHHHCC
PALADDSGLIVEAISPYPGVYSSRFYDIDFGGREEVRTNKDEANIRKLLRLLENTENRKA
CCEECCCCEEEEECCCCCCCCCCEEEECCCCCCHHHHCCCCHHHHHHHHHHHHCCCCCCE
KFVAFIVVYGGSWGIFAEGEVRGEITKEPRGDRGFGYDPVFVPEGYNKTMAELSPEEKNK
EEEEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCEECCCCCCCHHHHCCCHHHHH
ISHRGRALRKLVHVLKNCEKAF
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLLVATTNEGKYREIKEILSEYGIEVLKPEEKLEVEETGCTFLENAYLKARAYYERYKI
CEEEEEECCCCCHHHHHHHHHHCCCEEECCHHHCCHHHCCCHHHHHHHHHHHHHHHHHCC
PALADDSGLIVEAISPYPGVYSSRFYDIDFGGREEVRTNKDEANIRKLLRLLENTENRKA
CCEECCCCEEEEECCCCCCCCCCEEEECCCCCCHHHHCCCCHHHHHHHHHHHHCCCCCCE
KFVAFIVVYGGSWGIFAEGEVRGEITKEPRGDRGFGYDPVFVPEGYNKTMAELSPEEKNK
EEEEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCEECCCCCCCHHHHCCCHHHHH
ISHRGRALRKLVHVLKNCEKAF
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320