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The map label for this gene is rpl22p

Identifier: 11499504

GI number: 11499504

Start: 1721895

End: 1722362

Strand: Reverse

Name: rpl22p

Synonym: AF1920

Alternate gene names: 11499504

Gene position: 1722362-1721895 (Counterclockwise)

Preceding gene: 11499505

Following gene: 11499503

Centisome position: 79.07

GC content: 51.07

Gene sequence:

>468_bases
ATGCCTATGGCGAGGGTTAACTACGCTTACAAACCTGAGGATGAGACAAAGGCTGCGAAGGCGATGGGCTACGAGATGCC
GATCAGCTTCAAGCATGCCGTTGAAATTTGCAGGGCAATCAGGGGAAAGAAGATAGAGGAGGCAAGGAAGCTGCTTGAGG
ACGTTGTGGAGATGAAGAGGGCAATTCCCTTCAAGAGGCACAAGAAGAAGGTTGCACACAGAAGGGGATTGGAGAAGTGG
TATGCAGGAAGGTATCCTCAGAAGGCCGCAAAGTACGTGCTTAAGGTTCTGAGAAACCTTGAGGCGAATGCAGAGTATAA
GGGGCTTGATGTGGAGAATCTCGTCATAGTGCATGCTCAGGCCCAGAAGGGGAGGGTTATTGAGAGATACATGCCGAGAG
CATTTGGAAGGGCAACTCCGAGGTTTCAGCAGCTTACGACGGTAGAGCTTGTGGCAGAGGTGAGGTAA

Upstream 100 bases:

>100_bases
GGCACCGCCTCGGAGAGTTCGCACTGACGAGGCGCTTCGAGAAGCATTCAGGGCCCGGTGTTGGTGCTACGAGGAGCAGC
AAGTACGTCCCGCTGAAGTG

Downstream 100 bases:

>100_bases
TGGCGGTAGAGAGAAAGTTCGTTCAGGAGAGGTTGAAGAAGCTGATGGTCAAGGAGTGGATCAAGGATGAGGTGAGGAGT
GCAGGGTTTGGCGGAGTTGA

Product: 50S ribosomal protein L22P

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MPMARVNYAYKPEDETKAAKAMGYEMPISFKHAVEICRAIRGKKIEEARKLLEDVVEMKRAIPFKRHKKKVAHRRGLEKW
YAGRYPQKAAKYVLKVLRNLEANAEYKGLDVENLVIVHAQAQKGRVIERYMPRAFGRATPRFQQLTTVELVAEVR

Sequences:

>Translated_155_residues
MPMARVNYAYKPEDETKAAKAMGYEMPISFKHAVEICRAIRGKKIEEARKLLEDVVEMKRAIPFKRHKKKVAHRRGLEKW
YAGRYPQKAAKYVLKVLRNLEANAEYKGLDVENLVIVHAQAQKGRVIERYMPRAFGRATPRFQQLTTVELVAEVR
>Mature_154_residues
PMARVNYAYKPEDETKAAKAMGYEMPISFKHAVEICRAIRGKKIEEARKLLEDVVEMKRAIPFKRHKKKVAHRRGLEKWY
AGRYPQKAAKYVLKVLRNLEANAEYKGLDVENLVIVHAQAQKGRVIERYMPRAFGRATPRFQQLTTVELVAEVR

Specific function: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome

COG id: COG0091

COG function: function code J; Ribosomal protein L22

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribosomal protein L22P family

Homologues:

Organism=Homo sapiens, GI78000186, Length=148, Percent_Identity=37.8378378378378, Blast_Score=108, Evalue=2e-24,
Organism=Homo sapiens, GI4506617, Length=148, Percent_Identity=37.8378378378378, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI25143462, Length=151, Percent_Identity=36.4238410596026, Blast_Score=107, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI25143465, Length=149, Percent_Identity=32.8859060402685, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322668, Length=152, Percent_Identity=35.5263157894737, Blast_Score=81, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6322284, Length=152, Percent_Identity=34.8684210526316, Blast_Score=80, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24640202, Length=146, Percent_Identity=32.8767123287671, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI18921137, Length=146, Percent_Identity=32.8767123287671, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24640206, Length=146, Percent_Identity=32.8767123287671, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24640204, Length=146, Percent_Identity=32.8767123287671, Blast_Score=94, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RL22_ARCFU (O28359)

Other databases:

- EMBL:   AE000782
- PIR:   G69489
- RefSeq:   NP_070745.1
- ProteinModelPortal:   O28359
- SMR:   O28359
- GeneID:   1485143
- GenomeReviews:   AE000782_GR
- KEGG:   afu:AF1920
- NMPDR:   fig|224325.1.peg.1906
- TIGR:   AF_1920
- HOGENOM:   HBG568696
- OMA:   ANAEYKG
- ProtClustDB:   PRK04223
- BioCyc:   AFUL224325:AF_1920-MONOMER
- GO:   GO:0006412
- HAMAP:   MF_01331_A
- InterPro:   IPR001063
- InterPro:   IPR005721
- Gene3D:   G3DSA:3.90.470.10
- PANTHER:   PTHR11593
- TIGRFAMs:   TIGR01038

Pfam domain/function: PF00237 Ribosomal_L22; SSF54843 Ribosomal_L22

EC number: NA

Molecular weight: Translated: 18026; Mature: 17895

Theoretical pI: Translated: 10.66; Mature: 10.66

Prosite motif: PS00464 RIBOSOMAL_L22

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMARVNYAYKPEDETKAAKAMGYEMPISFKHAVEICRAIRGKKIEEARKLLEDVVEMKR
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AIPFKRHKKKVAHRRGLEKWYAGRYPQKAAKYVLKVLRNLEANAEYKGLDVENLVIVHAQ
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECC
AQKGRVIERYMPRAFGRATPRFQQLTTVELVAEVR
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PMARVNYAYKPEDETKAAKAMGYEMPISFKHAVEICRAIRGKKIEEARKLLEDVVEMKR
CCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AIPFKRHKKKVAHRRGLEKWYAGRYPQKAAKYVLKVLRNLEANAEYKGLDVENLVIVHAQ
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECC
AQKGRVIERYMPRAFGRATPRFQQLTTVELVAEVR
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475