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The map label for this gene is ilvH

Identifier: 11499308

GI number: 11499308

Start: 1539342

End: 1539821

Strand: Reverse

Name: ilvH

Synonym: AF1719

Alternate gene names: 11499308

Gene position: 1539821-1539342 (Counterclockwise)

Preceding gene: 11499309

Following gene: 11499307

Centisome position: 70.69

GC content: 49.58

Gene sequence:

>480_bases
GTGAAGCACACGATAGCCGTTCTGGTTGAGAACAAGCCCGGAGTCCTTGCGAGGGTTGCGGGACTGTTCAGGAGGAGGGG
TTTCAACATAGAGAGCCTGACAGTCGGCACCACCGAAAGAGATGACCTTTCAAGAATGACGATTGTCGTTGAAGGAGACG
ACAAGGTCGTTGAGCAGGTGATTAAGCAGCTGAACAAGCTCATTGAAACAATCAAGGTCAGCGAGATTACAGAAAGCTCT
GTCGAAAGAGAGCTGTGCCTCATCAGAGTTCACGCACCTCCAGAGAAGAGGGGCGAAATTGTGGAGCTCACAAACATCTT
CAGAGCGAGAATAGTTGACGTCTCCAGAGACAGCTTCATTATTGAGGTCACGGGCGATGAAGACAAGGTCTCGGCGTTCA
TTGACTTGATGAGGCAGTACGGCATCAAGGAGCTTGCAAGAACCGGAAAAGTGGCAATGGTAAGAGGAAACAAAAAATGA

Upstream 100 bases:

>100_bases
GGTCATAGACTTCAGAGTTGACTACCAGGCAAACGTCTTCCCGATGGTCCCGCCGGGAGCGGCGTTAAACGAGATTATCG
ATGAGGAGTGAGGTGGTAGC

Downstream 100 bases:

>100_bases
ATTTCAACATTGTAATTATGAGAAAAACTTAAATATGGTAGTGTTCATTATAATGATAGGTGGTAGTGATGGTGAAAATC
GTTCACGCTCAAACAGTGCT

Product: acetolactate synthase 3 regulatory subunit

Products: NA

Alternate protein names: Acetohydroxy-acid synthase small subunit; AHAS; ALS

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MKHTIAVLVENKPGVLARVAGLFRRRGFNIESLTVGTTERDDLSRMTIVVEGDDKVVEQVIKQLNKLIETIKVSEITESS
VERELCLIRVHAPPEKRGEIVELTNIFRARIVDVSRDSFIIEVTGDEDKVSAFIDLMRQYGIKELARTGKVAMVRGNKK

Sequences:

>Translated_159_residues
MKHTIAVLVENKPGVLARVAGLFRRRGFNIESLTVGTTERDDLSRMTIVVEGDDKVVEQVIKQLNKLIETIKVSEITESS
VERELCLIRVHAPPEKRGEIVELTNIFRARIVDVSRDSFIIEVTGDEDKVSAFIDLMRQYGIKELARTGKVAMVRGNKK
>Mature_159_residues
MKHTIAVLVENKPGVLARVAGLFRRRGFNIESLTVGTTERDDLSRMTIVVEGDDKVVEQVIKQLNKLIETIKVSEITESS
VERELCLIRVHAPPEKRGEIVELTNIFRARIVDVSRDSFIIEVTGDEDKVSAFIDLMRQYGIKELARTGKVAMVRGNKK

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain

Homologues:

Organism=Escherichia coli, GI1786266, Length=160, Percent_Identity=44.375, Blast_Score=134, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6319837, Length=204, Percent_Identity=33.8235294117647, Blast_Score=110, Evalue=8e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ILVH_ARCFU (O28555)

Other databases:

- EMBL:   AE000782
- PIR:   F69464
- RefSeq:   NP_070547.1
- ProteinModelPortal:   O28555
- SMR:   O28555
- GeneID:   1484942
- GenomeReviews:   AE000782_GR
- KEGG:   afu:AF1719
- NMPDR:   fig|224325.1.peg.1708
- TIGR:   AF_1719
- HOGENOM:   HBG335310
- OMA:   IERELAM
- ProtClustDB:   PRK11895
- BioCyc:   AFUL224325:AF_1719-MONOMER
- BRENDA:   2.2.1.6
- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912
- TIGRFAMs:   TIGR00119

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C

EC number: =2.2.1.6

Molecular weight: Translated: 17933; Mature: 17933

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHTIAVLVENKPGVLARVAGLFRRRGFNIESLTVGTTERDDLSRMTIVVEGDDKVVEQV
CCCEEEEEEECCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEEEECCHHHHHHH
IKQLNKLIETIKVSEITESSVERELCLIRVHAPPEKRGEIVELTNIFRARIVDVSRDSFI
HHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCHHHHHHHHHHHEEECCCCEE
IEVTGDEDKVSAFIDLMRQYGIKELARTGKVAMVRGNKK
EEEECCHHHHHHHHHHHHHHCHHHHHHCCCEEEEECCCC
>Mature Secondary Structure
MKHTIAVLVENKPGVLARVAGLFRRRGFNIESLTVGTTERDDLSRMTIVVEGDDKVVEQV
CCCEEEEEEECCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEEEECCHHHHHHH
IKQLNKLIETIKVSEITESSVERELCLIRVHAPPEKRGEIVELTNIFRARIVDVSRDSFI
HHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCHHHHHHHHHHHEEECCCCEE
IEVTGDEDKVSAFIDLMRQYGIKELARTGKVAMVRGNKK
EEEECCHHHHHHHHHHHHHHCHHHHHHCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475