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The map label for this gene is gldA

Identifier: 11499264

GI number: 11499264

Start: 1503587

End: 1504642

Strand: Reverse

Name: gldA

Synonym: AF1674

Alternate gene names: 11499264

Gene position: 1504642-1503587 (Counterclockwise)

Preceding gene: 11499265

Following gene: 11499254

Centisome position: 69.07

GC content: 50.85

Gene sequence:

>1056_bases
ATGAGATTCAAGACGGTTGACCTTCCGTATCACGTGTACATTGGCGAAAACGTGATTTCAAAACTGCCGAAGGTTCTGAG
AAGTTTGGATGCAAACTACTTTCTTCTCCTGACGGATGAAGTTGTGAAGAATCTTGTAGTTGTCAATCTCAAAGAAACAC
TAAAGGACTTCGAATACGACATGATGCTCGTTGAGTCGGCAAAGATGGAGGAGGCAAGGAAAATCGTGCTGAGAGGAGGC
TTTGCAGACTATGATGCAGTTGTCGGTGTTGGTGGGGGGAAGGTTCTAGACGTTTCGAAAGTTGTTTCGTCAGAGCTTAA
CGCATCGATGATAAGCGTGCCCACCACAGCCTCTCACGACGGTATAGCTTCTCCGGTGGCGAGCTTCAAGGAGAACGGAA
AGCCGATATCCATTTCAACCAACCCCCCGTCGGCGGTGATTGCCGACCTGAACATTATAAAGAACTGTCCCATCAGGCTG
CTCAGGTCCGGCTACGGTGACCTCGTTTCAAACATCTCATCAGTGAAGGACTGGCAGCTTGCAAGAGACTTGGTTGGGGA
GGATTACAATGAGGTTGCTGCATCTATTGCCGTGATGCCAGCGCAGCTAATGGTGAGCAAGGCCGATGAGCTTGATTTAA
CGCTCCCGCCCCACCTGCTGATGCTGCTGAGGGGACTGATTATGAGCGGCGTTGCTATAGCCTTCGTGGGCTCAAGCAGA
CCCGCAAGCGGAGCGGAACACAAGTTCAGCCACGCTCTCGATTATCTCGGCTACGGGAACGGCACTCATGGAGAGCAGGT
TGCCCTCGGTACGATAATAATGGAGTACCTCCACGAAAAGTACTACGGGAGGGGTGACTGGGAGCAGATTAAGATGTCGC
TTGAGAAGGTCCATGCCCCGACAACGGCAAAGGAAATCGGCCTGACAAGGGAGCAGGTGATAGAGGCATTGATGCTTGCG
ACGAAGCTCAGAAAAAAGAGGTTCACAATTCTCGAAGCTGTAAAACCCACAAAAGAAGAGTTTGAGCTCGTTGTGGAGAA
GACAGGCGTGGCTTAA

Upstream 100 bases:

>100_bases
CTTTCCGGAGGAGCTTATGATGCTGCTTGAGAAATAGTCGATTAGATTTATATACTAATTCCACAGACTGTACACACTGG
TTTTACGAAGAGGTGGTAGC

Downstream 100 bases:

>100_bases
AGCTCGAGAGGTGCTTCACCGGAGCAGAGGATGTACAGAATATCCCCCTTTTCAAGCCTGGTGTCAGCCTCCGGCAGTAT
CACATCACCCCTCCTCACCA

Product: sn-glycerol-1-phosphate dehydrogenase (gldA)

Products: NA

Alternate protein names: G1P dehydrogenase; G1PDH; Enantiomeric glycerophosphate synthase; sn-glycerol-1-phosphate dehydrogenase

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MRFKTVDLPYHVYIGENVISKLPKVLRSLDANYFLLLTDEVVKNLVVVNLKETLKDFEYDMMLVESAKMEEARKIVLRGG
FADYDAVVGVGGGKVLDVSKVVSSELNASMISVPTTASHDGIASPVASFKENGKPISISTNPPSAVIADLNIIKNCPIRL
LRSGYGDLVSNISSVKDWQLARDLVGEDYNEVAASIAVMPAQLMVSKADELDLTLPPHLLMLLRGLIMSGVAIAFVGSSR
PASGAEHKFSHALDYLGYGNGTHGEQVALGTIIMEYLHEKYYGRGDWEQIKMSLEKVHAPTTAKEIGLTREQVIEALMLA
TKLRKKRFTILEAVKPTKEEFELVVEKTGVA

Sequences:

>Translated_351_residues
MRFKTVDLPYHVYIGENVISKLPKVLRSLDANYFLLLTDEVVKNLVVVNLKETLKDFEYDMMLVESAKMEEARKIVLRGG
FADYDAVVGVGGGKVLDVSKVVSSELNASMISVPTTASHDGIASPVASFKENGKPISISTNPPSAVIADLNIIKNCPIRL
LRSGYGDLVSNISSVKDWQLARDLVGEDYNEVAASIAVMPAQLMVSKADELDLTLPPHLLMLLRGLIMSGVAIAFVGSSR
PASGAEHKFSHALDYLGYGNGTHGEQVALGTIIMEYLHEKYYGRGDWEQIKMSLEKVHAPTTAKEIGLTREQVIEALMLA
TKLRKKRFTILEAVKPTKEEFELVVEKTGVA
>Mature_351_residues
MRFKTVDLPYHVYIGENVISKLPKVLRSLDANYFLLLTDEVVKNLVVVNLKETLKDFEYDMMLVESAKMEEARKIVLRGG
FADYDAVVGVGGGKVLDVSKVVSSELNASMISVPTTASHDGIASPVASFKENGKPISISTNPPSAVIADLNIIKNCPIRL
LRSGYGDLVSNISSVKDWQLARDLVGEDYNEVAASIAVMPAQLMVSKADELDLTLPPHLLMLLRGLIMSGVAIAFVGSSR
PASGAEHKFSHALDYLGYGNGTHGEQVALGTIIMEYLHEKYYGRGDWEQIKMSLEKVHAPTTAKEIGLTREQVIEALMLA
TKLRKKRFTILEAVKPTKEEFELVVEKTGVA

Specific function: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol-1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea

COG id: COG0371

COG function: function code C; Glycerol dehydrogenase and related enzymes

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycerol-1-phosphate dehydrogenase family

Homologues:

Organism=Escherichia coli, GI87082352, Length=282, Percent_Identity=24.822695035461, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): G1PDH_ARCFU (O28599)

Other databases:

- EMBL:   AE000782
- PIR:   A69459
- RefSeq:   NP_070502.1
- ProteinModelPortal:   O28599
- SMR:   O28599
- GeneID:   1484897
- GenomeReviews:   AE000782_GR
- KEGG:   afu:AF1674
- NMPDR:   fig|224325.1.peg.1663
- TIGR:   AF_1674
- HOGENOM:   HBG672951
- OMA:   ADWELAH
- ProtClustDB:   CLSK2746991
- BioCyc:   AFUL224325:AF_1674-MONOMER
- BRENDA:   1.1.1.261
- GO:   GO:0005737
- HAMAP:   MF_00497_A
- InterPro:   IPR002658
- InterPro:   IPR023002
- InterPro:   IPR016205
- PIRSF:   PIRSF000112

Pfam domain/function: PF01761 DHQ_synthase

EC number: =1.1.1.261

Molecular weight: Translated: 38450; Mature: 38450

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: BINDING 120-120 BINDING 124-124 BINDING 167-167 BINDING 251-251

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFKTVDLPYHVYIGENVISKLPKVLRSLDANYFLLLTDEVVKNLVVVNLKETLKDFEYD
CCCEEECCCEEEEECHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHEEEEHHHHHHHHHHH
MMLVESAKMEEARKIVLRGGFADYDAVVGVGGGKVLDVSKVVSSELNASMISVPTTASHD
HHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCEEHHHHHHHHHHCCCEEECCCCCCCC
GIASPVASFKENGKPISISTNPPSAVIADLNIIKNCPIRLLRSGYGDLVSNISSVKDWQL
CHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHH
ARDLVGEDYNEVAASIAVMPAQLMVSKADELDLTLPPHLLMLLRGLIMSGVAIAFVGSSR
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCC
PASGAEHKFSHALDYLGYGNGTHGEQVALGTIIMEYLHEKYYGRGDWEQIKMSLEKVHAP
CCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
TTAKEIGLTREQVIEALMLATKLRKKRFTILEAVKPTKEEFELVVEKTGVA
CCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MRFKTVDLPYHVYIGENVISKLPKVLRSLDANYFLLLTDEVVKNLVVVNLKETLKDFEYD
CCCEEECCCEEEEECHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHEEEEHHHHHHHHHHH
MMLVESAKMEEARKIVLRGGFADYDAVVGVGGGKVLDVSKVVSSELNASMISVPTTASHD
HHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCEEHHHHHHHHHHCCCEEECCCCCCCC
GIASPVASFKENGKPISISTNPPSAVIADLNIIKNCPIRLLRSGYGDLVSNISSVKDWQL
CHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHH
ARDLVGEDYNEVAASIAVMPAQLMVSKADELDLTLPPHLLMLLRGLIMSGVAIAFVGSSR
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCC
PASGAEHKFSHALDYLGYGNGTHGEQVALGTIIMEYLHEKYYGRGDWEQIKMSLEKVHAP
CCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
TTAKEIGLTREQVIEALMLATKLRKKRFTILEAVKPTKEEFELVVEKTGVA
CCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475