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Identifier: 11498922

GI number: 11498922

Start: 1183494

End: 1185011

Strand: Reverse

Name: Not Available

Synonym: AF1324

Alternate gene names: 11498922

Gene position: 1185011-1183494 (Counterclockwise)

Preceding gene: 11498924

Following gene: 11498920

Centisome position: 54.4

GC content: 52.24

Gene sequence:

>1518_bases
ATGGCCTCCATTCTTGCAGTTGATGTTGGGACCACCTCCATTAAAGCCGGGATTGTTAGCACCGAAAATTTTGAGGCTGA
GAGTACTCAATCAACAAGGGCTGTTGTGGAGTATCCGAAAAAGCACTGGGCTGAGAAGGATCCGGAAAAGCTGTGGAACA
GTATTGTTGAAGTTTGCAAGCCTCTGGCTGAGAAAGCAAATCCCGACGCCATTGTGTTTGGCGCCCACATGGCGGGGGTT
GTGCCTGTTGATGGAGAGGGCAACGCGCTGAGGAACATCATAACGTGGCTCGATGAAAGGGCTGCGGGACTGCCTGAGGA
CGTGTGGAAGGGTTTGATTAAAATTCAGGGCTACTCATTAACCAAGCTAATCAAATTTCTGCGTTTGACGGGGGGAGCAC
CGTCGAGGACGGGTAAAGACCCGATTTCAAAGATAGTCTGGATCAGGGAGAATGAGCCGGATGTTTTCGGCAAGACCTTC
AAGATGCTCGACGTTAGAGGATATTTGGTTGCGAGAGCCACCGGAAATTTTGTTACGAGTCCCGACGAAGCACACCTAAC
ATGGCTTGCAGACACCCGCGGAGGGAAGGCGAGGTGGTCTGAGAGCATCCTTAAAGATTATGCCTTGTCAGCCTCGCTCT
TCCCTGAGATAAAGAACTGCACAGAAATTGCCGGCTATCTTCGCCCTGAGGTGAGGAAGGAATTTGGATTAGAGGGGGAT
GTGCCGGTAATGGTTGGCTCTGGAGACGTTGCAGCTGCAGCCGTTGGCTCTGGAGCGGTGAAGGACTACGAGTGCCACAT
TTACGTCGGAACGAGTGACTGGGTTGCTGCCCACATTCCACAAAGAAAAACTGACATCTTCCACTTTATAGGGAGCCTGC
TGAGCGCCATTCCTGAGAAGTACTTGCTGATTGCCGAACAGGAAGTTGCTGCAGGCGCTCTGGAGTGGGCGATGAGGCTT
GTGGGCATTCAAGGAGAATACGAGCTGGTGAAGGAGCTTGTGGAGAAGGCTCCTGCAGGAAAGCTGATATTCATGCCGTG
GTTCTACGGCGAGAGGGCTCCAATCGACGACCCCTACGTTAGGGGAGGGCTGGTAAACGTGGGCCTCGACAGCGGGAGGG
AAGAGGTTCTGAGGGCGATGATGGAGGGGGTTGCATTGAACATCAAGTGGGTCTTTGGCTATGTGGAAAAGATGACCGCT
CCGCAGCAGATGGTGAGCATTGTCGGGGGAGGGGCGCTTTTTGACATCTGGTGTCAGATTATATCGAATGCCGTTAGAAG
GCCGCTGAGGAGGATAAAGCATCCTGAGGAAACTGGGTTGAGAGGTTTGGCTACAATGGCGGCGGTTGGGCTGGGGGAGG
AGAGCTTTGAAAGTGCAGCAGCGAAGTTCGAGGTTGACAGAGTTTTCAAGCCCGACGATGAGGAGGCAAAGGTTTACGAC
AGGCTTTTCGAATACTACAAGGAGCTTTACAGCAAGCTGAAAAAAGTTTACAGAAAGCTGAACTCAGCGGAATATTAG

Upstream 100 bases:

>100_bases
AGCCTGAGCATTGCCCCTAATCTTCGCTGGAGTATTAAAGCTTTAAACCTGAGTCGTTAATTGTAGAAAATTATAAATAT
TTTGCAACTCAATATTATTG

Downstream 100 bases:

>100_bases
CTCGTTGATGAATTGCTTGAACACGCTCTCAACAATCTCAGGCGGCATGGAGTGGATTAGCTCTGAAATAAGCTCTGAAT
CTTCTGGCAGTCCATCCTCA

Product: carbohydrate kinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 505; Mature: 504

Protein sequence:

>505_residues
MASILAVDVGTTSIKAGIVSTENFEAESTQSTRAVVEYPKKHWAEKDPEKLWNSIVEVCKPLAEKANPDAIVFGAHMAGV
VPVDGEGNALRNIITWLDERAAGLPEDVWKGLIKIQGYSLTKLIKFLRLTGGAPSRTGKDPISKIVWIRENEPDVFGKTF
KMLDVRGYLVARATGNFVTSPDEAHLTWLADTRGGKARWSESILKDYALSASLFPEIKNCTEIAGYLRPEVRKEFGLEGD
VPVMVGSGDVAAAAVGSGAVKDYECHIYVGTSDWVAAHIPQRKTDIFHFIGSLLSAIPEKYLLIAEQEVAAGALEWAMRL
VGIQGEYELVKELVEKAPAGKLIFMPWFYGERAPIDDPYVRGGLVNVGLDSGREEVLRAMMEGVALNIKWVFGYVEKMTA
PQQMVSIVGGGALFDIWCQIISNAVRRPLRRIKHPEETGLRGLATMAAVGLGEESFESAAAKFEVDRVFKPDDEEAKVYD
RLFEYYKELYSKLKKVYRKLNSAEY

Sequences:

>Translated_505_residues
MASILAVDVGTTSIKAGIVSTENFEAESTQSTRAVVEYPKKHWAEKDPEKLWNSIVEVCKPLAEKANPDAIVFGAHMAGV
VPVDGEGNALRNIITWLDERAAGLPEDVWKGLIKIQGYSLTKLIKFLRLTGGAPSRTGKDPISKIVWIRENEPDVFGKTF
KMLDVRGYLVARATGNFVTSPDEAHLTWLADTRGGKARWSESILKDYALSASLFPEIKNCTEIAGYLRPEVRKEFGLEGD
VPVMVGSGDVAAAAVGSGAVKDYECHIYVGTSDWVAAHIPQRKTDIFHFIGSLLSAIPEKYLLIAEQEVAAGALEWAMRL
VGIQGEYELVKELVEKAPAGKLIFMPWFYGERAPIDDPYVRGGLVNVGLDSGREEVLRAMMEGVALNIKWVFGYVEKMTA
PQQMVSIVGGGALFDIWCQIISNAVRRPLRRIKHPEETGLRGLATMAAVGLGEESFESAAAKFEVDRVFKPDDEEAKVYD
RLFEYYKELYSKLKKVYRKLNSAEY
>Mature_504_residues
ASILAVDVGTTSIKAGIVSTENFEAESTQSTRAVVEYPKKHWAEKDPEKLWNSIVEVCKPLAEKANPDAIVFGAHMAGVV
PVDGEGNALRNIITWLDERAAGLPEDVWKGLIKIQGYSLTKLIKFLRLTGGAPSRTGKDPISKIVWIRENEPDVFGKTFK
MLDVRGYLVARATGNFVTSPDEAHLTWLADTRGGKARWSESILKDYALSASLFPEIKNCTEIAGYLRPEVRKEFGLEGDV
PVMVGSGDVAAAAVGSGAVKDYECHIYVGTSDWVAAHIPQRKTDIFHFIGSLLSAIPEKYLLIAEQEVAAGALEWAMRLV
GIQGEYELVKELVEKAPAGKLIFMPWFYGERAPIDDPYVRGGLVNVGLDSGREEVLRAMMEGVALNIKWVFGYVEKMTAP
QQMVSIVGGGALFDIWCQIISNAVRRPLRRIKHPEETGLRGLATMAAVGLGEESFESAAAKFEVDRVFKPDDEEAKVYDR
LFEYYKELYSKLKKVYRKLNSAEY

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI88196792, Length=528, Percent_Identity=23.4848484848485, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI42794763, Length=461, Percent_Identity=21.6919739696312, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI189409120, Length=461, Percent_Identity=22.3427331887202, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI4504007, Length=461, Percent_Identity=22.3427331887202, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1789987, Length=503, Percent_Identity=26.2425447316103, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1790005, Length=519, Percent_Identity=23.6994219653179, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1789168, Length=488, Percent_Identity=24.5901639344262, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1787789, Length=526, Percent_Identity=22.6235741444867, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17535599, Length=418, Percent_Identity=23.2057416267943, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17864214, Length=496, Percent_Identity=24.3951612903226, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24654573, Length=428, Percent_Identity=23.5981308411215, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 55860; Mature: 55729

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASILAVDVGTTSIKAGIVSTENFEAESTQSTRAVVEYPKKHWAEKDPEKLWNSIVEVCK
CCCEEEEECCCCHHHCCEEECCCCCCCCCHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHH
PLAEKANPDAIVFGAHMAGVVPVDGEGNALRNIITWLDERAAGLPEDVWKGLIKIQGYSL
HHHHCCCCCEEEEECCCCCEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCH
TKLIKFLRLTGGAPSRTGKDPISKIVWIRENEPDVFGKTFKMLDVRGYLVARATGNFVTS
HHHHHHHHHCCCCCCCCCCCCHHHEEEEECCCCCHHHHHHHHHHHCEEEEEEECCCCCCC
PDEAHLTWLADTRGGKARWSESILKDYALSASLFPEIKNCTEIAGYLRPEVRKEFGLEGD
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCC
VPVMVGSGDVAAAAVGSGAVKDYECHIYVGTSDWVAAHIPQRKTDIFHFIGSLLSAIPEK
CEEEECCCCCHHHHHCCCCCCCEEEEEEECCCCCCEECCCCHHHHHHHHHHHHHHHCCHH
YLLIAEQEVAAGALEWAMRLVGIQGEYELVKELVEKAPAGKLIFMPWFYGERAPIDDPYV
HEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHH
RGGLVNVGLDSGREEVLRAMMEGVALNIKWVFGYVEKMTAPQQMVSIVGGGALFDIWCQI
CCCEEEECCCCCHHHHHHHHHHCCEEEEHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHH
ISNAVRRPLRRIKHPEETGLRGLATMAAVGLGEESFESAAAKFEVDRVFKPDDEEAKVYD
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHEEHHCCCCCCCHHHHHHH
RLFEYYKELYSKLKKVYRKLNSAEY
HHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ASILAVDVGTTSIKAGIVSTENFEAESTQSTRAVVEYPKKHWAEKDPEKLWNSIVEVCK
CCEEEEECCCCHHHCCEEECCCCCCCCCHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHH
PLAEKANPDAIVFGAHMAGVVPVDGEGNALRNIITWLDERAAGLPEDVWKGLIKIQGYSL
HHHHCCCCCEEEEECCCCCEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCH
TKLIKFLRLTGGAPSRTGKDPISKIVWIRENEPDVFGKTFKMLDVRGYLVARATGNFVTS
HHHHHHHHHCCCCCCCCCCCCHHHEEEEECCCCCHHHHHHHHHHHCEEEEEEECCCCCCC
PDEAHLTWLADTRGGKARWSESILKDYALSASLFPEIKNCTEIAGYLRPEVRKEFGLEGD
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCC
VPVMVGSGDVAAAAVGSGAVKDYECHIYVGTSDWVAAHIPQRKTDIFHFIGSLLSAIPEK
CEEEECCCCCHHHHHCCCCCCCEEEEEEECCCCCCEECCCCHHHHHHHHHHHHHHHCCHH
YLLIAEQEVAAGALEWAMRLVGIQGEYELVKELVEKAPAGKLIFMPWFYGERAPIDDPYV
HEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHH
RGGLVNVGLDSGREEVLRAMMEGVALNIKWVFGYVEKMTAPQQMVSIVGGGALFDIWCQI
CCCEEEECCCCCHHHHHHHHHHCCEEEEHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHH
ISNAVRRPLRRIKHPEETGLRGLATMAAVGLGEESFESAAAKFEVDRVFKPDDEEAKVYD
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHEEHHCCCCCCCHHHHHHH
RLFEYYKELYSKLKKVYRKLNSAEY
HHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2994009 [H]