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Identifier: 11498906

GI number: 11498906

Start: 1167020

End: 1167751

Strand: Reverse

Name: Not Available

Synonym: AF1308

Alternate gene names: NA

Gene position: 1167751-1167020 (Counterclockwise)

Preceding gene: 11498907

Following gene: 11498904

Centisome position: 53.61

GC content: 52.6

Gene sequence:

>732_bases
ATGCGTTGCCTCCTTCTCGGTGGTTTCACTCTACTATCACGGCTCTGCAGGTCCACTGCTGCTTCCTCTGGCAGCTTTCG
CAACGGTTGTGGAGGCTGTAACTCCCAAGGGGCTGGACAACCTGAGCGTTTCAATTTTAACCGCAATACTATACTTCTGG
ATGGCATGAGGTTCATAGTTATCGACGGGATGGATGGTGCCGGGAAAGACACACACGCGGAGTTCGTTAGGCGCAGGTAC
GCCGAAAGGGGGAGCGTTATTGTGAGAACGCATCCGTCCGACTCTCTGTTCGGCAGAGTTGCGAAGGCCAGCCTCCTCAG
AAGGGGAAAATTCTTCCACCTCATGGCGGCGATTTTCTACTTCTTCGACGTGATTTACTCCCTGCTCAGATACTACGGAA
GGGCTGAAACCGTGATTTTCGTCAGGTATCTCGGAGGAGTGCTTTACTTGCCGGAAAGGTACGCAAGGGTGCTTTACAGG
TTTTTCCGCTCCGTTCTTCCGACCTCTCCCTACATGTTCTACCTCGAAGCTGAGCCGGAAGTCTGCATGGAGAGGGTGGC
AAGAAGAAGCGAGAGCGAGATGTTCGAGAACATCGAGGACTTCAGGAGGGTCAGGGAGAGGGCGTTCAGAATACTGAAAG
GCTGGAAGTTCATCAACACAAACAGACCGATAGAGGAGACGAGAAGGGAGATTGAAAGAATTCTCAGCGAGCTCGACAGA
CGATTTCCCTGA

Upstream 100 bases:

>100_bases
ACGGTCTCGCATCTCTGATTGGGGGTAGGTATGGTAAGAGAAAGTTCAGGATTTTGGGAGACGAGAAAAGCCTGGAGGGC
AGCGTTGCTATGTTTCTGGG

Downstream 100 bases:

>100_bases
AGTGCTCTGGAACGAACTCCTCAGCCTCAACTCCGGCGGCGGTGCTGAACTGGTAGACCATTATGTAGCCCGCGAGGTGG
AAAGGGGCCTCCTTGAGCTC

Product: thymidylate kinase, putative

Products: ADP; dTDP

Alternate protein names: Thymidylate Kinase-Related Protein

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MRCLLLGGFTLLSRLCRSTAASSGSFRNGCGGCNSQGAGQPERFNFNRNTILLDGMRFIVIDGMDGAGKDTHAEFVRRRY
AERGSVIVRTHPSDSLFGRVAKASLLRRGKFFHLMAAIFYFFDVIYSLLRYYGRAETVIFVRYLGGVLYLPERYARVLYR
FFRSVLPTSPYMFYLEAEPEVCMERVARRSESEMFENIEDFRRVRERAFRILKGWKFINTNRPIEETRREIERILSELDR
RFP

Sequences:

>Translated_243_residues
MRCLLLGGFTLLSRLCRSTAASSGSFRNGCGGCNSQGAGQPERFNFNRNTILLDGMRFIVIDGMDGAGKDTHAEFVRRRY
AERGSVIVRTHPSDSLFGRVAKASLLRRGKFFHLMAAIFYFFDVIYSLLRYYGRAETVIFVRYLGGVLYLPERYARVLYR
FFRSVLPTSPYMFYLEAEPEVCMERVARRSESEMFENIEDFRRVRERAFRILKGWKFINTNRPIEETRREIERILSELDR
RFP
>Mature_243_residues
MRCLLLGGFTLLSRLCRSTAASSGSFRNGCGGCNSQGAGQPERFNFNRNTILLDGMRFIVIDGMDGAGKDTHAEFVRRRY
AERGSVIVRTHPSDSLFGRVAKASLLRRGKFFHLMAAIFYFFDVIYSLLRYYGRAETVIFVRYLGGVLYLPERYARVLYR
FFRSVLPTSPYMFYLEAEPEVCMERVARRSESEMFENIEDFRRVRERAFRILKGWKFINTNRPIEETRREIERILSELDR
RFP

Specific function: Unknown

COG id: COG0125

COG function: function code F; Thymidylate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.4.9

Molecular weight: Translated: 28434; Mature: 28434

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCLLLGGFTLLSRLCRSTAASSGSFRNGCGGCNSQGAGQPERFNFNRNTILLDGMRFIV
CEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEE
IDGMDGAGKDTHAEFVRRRYAERGSVIVRTHPSDSLFGRVAKASLLRRGKFFHLMAAIFY
EECCCCCCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
FFDVIYSLLRYYGRAETVIFVRYLGGVLYLPERYARVLYRFFRSVLPTSPYMFYLEAEPE
HHHHHHHHHHHHCCHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHCCCCCEEEEEECCHH
VCMERVARRSESEMFENIEDFRRVRERAFRILKGWKFINTNRPIEETRREIERILSELDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHH
RFP
CCC
>Mature Secondary Structure
MRCLLLGGFTLLSRLCRSTAASSGSFRNGCGGCNSQGAGQPERFNFNRNTILLDGMRFIV
CEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEE
IDGMDGAGKDTHAEFVRRRYAERGSVIVRTHPSDSLFGRVAKASLLRRGKFFHLMAAIFY
EECCCCCCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
FFDVIYSLLRYYGRAETVIFVRYLGGVLYLPERYARVLYRFFRSVLPTSPYMFYLEAEPE
HHHHHHHHHHHHCCHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHCCCCCEEEEEECCHH
VCMERVARRSESEMFENIEDFRRVRERAFRILKGWKFINTNRPIEETRREIERILSELDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHH
RFP
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dTMP

Specific reaction: ATP + dTMP = ADP + dTDP

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA