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The map label for this gene is rpoE1

Identifier: 11498717

GI number: 11498717

Start: 997506

End: 998075

Strand: Reverse

Name: rpoE1

Synonym: AF1117

Alternate gene names: 11498717

Gene position: 998075-997506 (Counterclockwise)

Preceding gene: 11498718

Following gene: 11498716

Centisome position: 45.82

GC content: 50.35

Gene sequence:

>570_bases
ATGTACGCCCGTATAAAACTCAGAGATACTGTTAGGGTTCCTCCATCAAAGCTTGGAGAGGATATTGAAAAGGTAATCAA
CTCCCTCCTCTGGGAGCAGTTTGAGGGCAGGCTCGACAGAGAGTACGGAATGATCATAGGCATCGAAAGCATAGAAGAGA
TAGGAGAGGGCAGAATTATTGAAGGGGACGGAGGAGTTTACTTCGACGTCGTTTTCAATGCTATATGCTTCAGACCGCTC
CACCAAGAGGTCGTGGAGGGGGAGGTCATCGAAATCGTAGAGTTCGGAGCGTTCGTTTCCATCGGCCCATTCGACGCTCT
TCTGCACATGAGTCAGGTTACCGATGACTACATGGTGTTTGACGAGAAGAACAAGAGGCTGGTGGGGAGGGAAACTAAAA
AGGTTCTTCAGGAGGGTGACAAGGTAAGGGCAAGAATCGTTTCGCTCAGCCTCAAGGAGAGAGAGCCTGAGAAGAGCAAG
ATTGGTCTCACCATGAGGCAGCCCTGGCTTGGGGCGCTGAAGTGGATTGAGGAGGAGATTGAGAAGCTCATGAAGGAGAG
TGGGGTTTGA

Upstream 100 bases:

>100_bases
TTAAGCTTTTCAGCAAAATCGATGAGGCCTGGGTTTGATTTACATTCTTAGTTAAATTTATATTGCTTCCCGACCCAGCA
AAGGCTGCGGTGATGATTTT

Downstream 100 bases:

>100_bases
TGGCCGAGCTTGCATGCAAGAACTGCAGGTTCATAAATGTTGACACCAACATCTGCAGAAATTGCGGAAGCACTGACCTG
ACGAAGGAGTGGTACGGTTA

Product: DNA-directed RNA polymerase subunit E'

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MYARIKLRDTVRVPPSKLGEDIEKVINSLLWEQFEGRLDREYGMIIGIESIEEIGEGRIIEGDGGVYFDVVFNAICFRPL
HQEVVEGEVIEIVEFGAFVSIGPFDALLHMSQVTDDYMVFDEKNKRLVGRETKKVLQEGDKVRARIVSLSLKEREPEKSK
IGLTMRQPWLGALKWIEEEIEKLMKESGV

Sequences:

>Translated_189_residues
MYARIKLRDTVRVPPSKLGEDIEKVINSLLWEQFEGRLDREYGMIIGIESIEEIGEGRIIEGDGGVYFDVVFNAICFRPL
HQEVVEGEVIEIVEFGAFVSIGPFDALLHMSQVTDDYMVFDEKNKRLVGRETKKVLQEGDKVRARIVSLSLKEREPEKSK
IGLTMRQPWLGALKWIEEEIEKLMKESGV
>Mature_189_residues
MYARIKLRDTVRVPPSKLGEDIEKVINSLLWEQFEGRLDREYGMIIGIESIEEIGEGRIIEGDGGVYFDVVFNAICFRPL
HQEVVEGEVIEIVEFGAFVSIGPFDALLHMSQVTDDYMVFDEKNKRLVGRETKKVLQEGDKVRARIVSLSLKEREPEKSK
IGLTMRQPWLGALKWIEEEIEKLMKESGV

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG1095

COG function: function code K; DNA-directed RNA polymerase, subunit E'

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI4505947, Length=157, Percent_Identity=27.3885350318471, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17510349, Length=149, Percent_Identity=28.1879194630872, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17566938, Length=193, Percent_Identity=29.0155440414508, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322705, Length=168, Percent_Identity=26.1904761904762, Blast_Score=63, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24647020, Length=148, Percent_Identity=29.0540540540541, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR005576
- InterPro:   IPR004519 [H]

Pfam domain/function: PF03876 RNA_pol_Rpb7_N; PF00575 S1 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 21686; Mature: 21686

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS50126 S1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYARIKLRDTVRVPPSKLGEDIEKVINSLLWEQFEGRLDREYGMIIGIESIEEIGEGRII
CCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHCCCCEE
EGDGGVYFDVVFNAICFRPLHQEVVEGEVIEIVEFGAFVSIGPFDALLHMSQVTDDYMVF
ECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCEEEECHHHHHHHHHHCCCCCEEE
DEKNKRLVGRETKKVLQEGDKVRARIVSLSLKEREPEKSKIGLTMRQPWLGALKWIEEEI
ECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHCCCEECCHHHHHHHHHHHHH
EKLMKESGV
HHHHHHCCC
>Mature Secondary Structure
MYARIKLRDTVRVPPSKLGEDIEKVINSLLWEQFEGRLDREYGMIIGIESIEEIGEGRII
CCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHCCCCEE
EGDGGVYFDVVFNAICFRPLHQEVVEGEVIEIVEFGAFVSIGPFDALLHMSQVTDDYMVF
ECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCEEEECHHHHHHHHHHCCCCCEEE
DEKNKRLVGRETKKVLQEGDKVRARIVSLSLKEREPEKSKIGLTMRQPWLGALKWIEEEI
ECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHCCCEECCHHHHHHHHHHHHH
EKLMKESGV
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]