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The map label for this gene is ftsA-1

Identifier: 11498675

GI number: 11498675

Start: 974292

End: 975533

Strand: Reverse

Name: ftsA-1

Synonym: AF1070

Alternate gene names: 11498675

Gene position: 975533-974292 (Counterclockwise)

Preceding gene: 11498677

Following gene: 11498674

Centisome position: 44.78

GC content: 51.05

Gene sequence:

>1242_bases
ATGAAAGATGTCGCAAGGGATATATACCTCTCACGGGACAAGATTGATGAAATCAAGCGAAAAAGATTCAGAAGCACTTT
AAAGTATGTTTACGATAACTCGCCATTTTACAGGAGGCTTTTCAAGGAGAGCGGTGTAGACATCGACTCTATAAAGGAGC
CCGCTGACATAGCAAAGCTCCCCTTCACCACAAAGCAGAATCTCCGCGAGAGCTATCCGCTCAAAATGGCCTGCGTTGAA
AAGGAGAAGATCGTCAGAATTCAGATGAGCGGAGGAACGACGGGCCAGCCTGTAATCATCCCCTACACCCGCCACGATGT
GGAGCAGTGGAAGGAGATGCTTCTAAGGGACTTCTACCTTGCGGGAATAACCTCAAAGGACGTAATTCAGATTACGCCCG
CCTTCGGACTGTGGAACGGTGGTTTTGGCTTCCACTTTGCCGCTGACGCAATAGATGCTTTCGTAATACCAATTGGCGCG
GGAAACACGAGAAATCAGGTCAGATTCATGGTCGACTTCGGCACGACTGTGCTTTGTGCCACTGCAAGCTATCCTCTGAG
AATTGCAGAGGTTGCTGAGGAGATGGGCTACGAGCCAGCAGAGCTGCCTGTCCAGAAGATGCTGCTTGGTGCTGAGCCAT
GGAGCGAGGAGATGAGGAGGCAGATTGAGAAAACTTTCAACTGCAAAGCCTTTGACATCCCCGGCCTGACGGAGATGGGG
GGTGTTGGGACTGTTGGCTTTGAGTGTCCCAGCAGAAACGGCCTGCACATATGGGAGGACAACTACATCGTCGAAATAGT
TGACCCGGAAACGGGTGAAGTTTTGGAGGATGGAGAGGAGGGCGAGATAGTTTACACGTCCCTCAACAGGGAGGCGATGC
CCCTCATAAGGTATCGCAGCGGTGAGGTCTCTGCTGTAGTTTCGAGGGAGAAGTGTGAATGCGGCATTGAGCACATGACG
ATAAAGAGGATAAGAGGCAGAACGGACGACATGGTGATTTACAAGGGAGTTAAGTTCTACCCGAGCGACGTGGAGCAGAT
TCTCGCATCCTATGGAGTGAGGCACTACAGAATTGAGGTTGGTGAGGGGATAAGGGTGATTTTCGAGGGTGAAAACGGAC
TTGCGAGGAAGGTTATAAAGGACATAAAGGAGTTCCTGGGGTTCAGTCCGAGGATTGAGGTCGTGCAGCCCGGATCACTT
GAGAGGTTTGAGGGTAAGGCAAAAAGGCTCTTCAGGGGGTGA

Upstream 100 bases:

>100_bases
CTCACGTGCTTATCCCATATTTTGCGATAAATCCTACGAAAAAGGTATTAACCTAAATCAAGGGAAAGTTTTTTAAATCA
ACACTCCTGTCTTTTCTAAC

Downstream 100 bases:

>100_bases
AAAAATGGTTATTGCAACTGTTTATGCGGCCTCTATTGGCCTGATGGTGTTTGGATTTGCCGTGGCACTGTTCAAGGCGA
GGAGGATGGCATGATTATTG

Product: coenzyme F390 synthetase (ftsA-1)

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MKDVARDIYLSRDKIDEIKRKRFRSTLKYVYDNSPFYRRLFKESGVDIDSIKEPADIAKLPFTTKQNLRESYPLKMACVE
KEKIVRIQMSGGTTGQPVIIPYTRHDVEQWKEMLLRDFYLAGITSKDVIQITPAFGLWNGGFGFHFAADAIDAFVIPIGA
GNTRNQVRFMVDFGTTVLCATASYPLRIAEVAEEMGYEPAELPVQKMLLGAEPWSEEMRRQIEKTFNCKAFDIPGLTEMG
GVGTVGFECPSRNGLHIWEDNYIVEIVDPETGEVLEDGEEGEIVYTSLNREAMPLIRYRSGEVSAVVSREKCECGIEHMT
IKRIRGRTDDMVIYKGVKFYPSDVEQILASYGVRHYRIEVGEGIRVIFEGENGLARKVIKDIKEFLGFSPRIEVVQPGSL
ERFEGKAKRLFRG

Sequences:

>Translated_413_residues
MKDVARDIYLSRDKIDEIKRKRFRSTLKYVYDNSPFYRRLFKESGVDIDSIKEPADIAKLPFTTKQNLRESYPLKMACVE
KEKIVRIQMSGGTTGQPVIIPYTRHDVEQWKEMLLRDFYLAGITSKDVIQITPAFGLWNGGFGFHFAADAIDAFVIPIGA
GNTRNQVRFMVDFGTTVLCATASYPLRIAEVAEEMGYEPAELPVQKMLLGAEPWSEEMRRQIEKTFNCKAFDIPGLTEMG
GVGTVGFECPSRNGLHIWEDNYIVEIVDPETGEVLEDGEEGEIVYTSLNREAMPLIRYRSGEVSAVVSREKCECGIEHMT
IKRIRGRTDDMVIYKGVKFYPSDVEQILASYGVRHYRIEVGEGIRVIFEGENGLARKVIKDIKEFLGFSPRIEVVQPGSL
ERFEGKAKRLFRG
>Mature_413_residues
MKDVARDIYLSRDKIDEIKRKRFRSTLKYVYDNSPFYRRLFKESGVDIDSIKEPADIAKLPFTTKQNLRESYPLKMACVE
KEKIVRIQMSGGTTGQPVIIPYTRHDVEQWKEMLLRDFYLAGITSKDVIQITPAFGLWNGGFGFHFAADAIDAFVIPIGA
GNTRNQVRFMVDFGTTVLCATASYPLRIAEVAEEMGYEPAELPVQKMLLGAEPWSEEMRRQIEKTFNCKAFDIPGLTEMG
GVGTVGFECPSRNGLHIWEDNYIVEIVDPETGEVLEDGEEGEIVYTSLNREAMPLIRYRSGEVSAVVSREKCECGIEHMT
IKRIRGRTDDMVIYKGVKFYPSDVEQILASYGVRHYRIEVGEGIRVIFEGENGLARKVIKDIKEFLGFSPRIEVVQPGSL
ERFEGKAKRLFRG

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=421, Percent_Identity=35.3919239904988, Blast_Score=280, Evalue=2e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 46994; Mature: 46994

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDVARDIYLSRDKIDEIKRKRFRSTLKYVYDNSPFYRRLFKESGVDIDSIKEPADIAKL
CCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHCCCCHHHHHC
PFTTKQNLRESYPLKMACVEKEKIVRIQMSGGTTGQPVIIPYTRHDVEQWKEMLLRDFYL
CCCCHHHHHHCCCEEEEEECCCEEEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHH
AGITSKDVIQITPAFGLWNGGFGFHFAADAIDAFVIPIGAGNTRNQVRFMVDFGTTVLCA
HCCCCCCEEEEECCCCCCCCCCCCEEHHHCCCEEEEEECCCCCCCEEEEEEECCCEEEEE
TASYPLRIAEVAEEMGYEPAELPVQKMLLGAEPWSEEMRRQIEKTFNCKAFDIPGLTEMG
CCCCCCHHHHHHHHHCCCCHHCCHHHHHHCCCCHHHHHHHHHHHHCCCEEECCCCCHHCC
GVGTVGFECPSRNGLHIWEDNYIVEIVDPETGEVLEDGEEGEIVYTSLNREAMPLIRYRS
CCCEEEEECCCCCCCEEECCCEEEEEECCCCCCHHCCCCCCCEEEEECCCCCCCEEEECC
GEVSAVVSREKCECGIEHMTIKRIRGRTDDMVIYKGVKFYPSDVEQILASYGVRHYRIEV
CCEEEEEEHHHHHCCHHHHHHHHHCCCCCCEEEEECCEECCHHHHHHHHHCCCEEEEEEE
GEGIRVIFEGENGLARKVIKDIKEFLGFSPRIEVVQPGSLERFEGKAKRLFRG
CCCEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHCCHHHHHCCC
>Mature Secondary Structure
MKDVARDIYLSRDKIDEIKRKRFRSTLKYVYDNSPFYRRLFKESGVDIDSIKEPADIAKL
CCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHCCCCHHHHHC
PFTTKQNLRESYPLKMACVEKEKIVRIQMSGGTTGQPVIIPYTRHDVEQWKEMLLRDFYL
CCCCHHHHHHCCCEEEEEECCCEEEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHH
AGITSKDVIQITPAFGLWNGGFGFHFAADAIDAFVIPIGAGNTRNQVRFMVDFGTTVLCA
HCCCCCCEEEEECCCCCCCCCCCCEEHHHCCCEEEEEECCCCCCCEEEEEEECCCEEEEE
TASYPLRIAEVAEEMGYEPAELPVQKMLLGAEPWSEEMRRQIEKTFNCKAFDIPGLTEMG
CCCCCCHHHHHHHHHCCCCHHCCHHHHHHCCCCHHHHHHHHHHHHCCCEEECCCCCHHCC
GVGTVGFECPSRNGLHIWEDNYIVEIVDPETGEVLEDGEEGEIVYTSLNREAMPLIRYRS
CCCEEEEECCCCCCCEEECCCEEEEEECCCCCCHHCCCCCCCEEEEECCCCCCCEEEECC
GEVSAVVSREKCECGIEHMTIKRIRGRTDDMVIYKGVKFYPSDVEQILASYGVRHYRIEV
CCEEEEEEHHHHHCCHHHHHHHHHCCCCCCEEEEECCEECCHHHHHHHHHCCCEEEEEEE
GEGIRVIFEGENGLARKVIKDIKEFLGFSPRIEVVQPGSLERFEGKAKRLFRG
CCCEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]