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Identifier: 11498669

GI number: 11498669

Start: 968515

End: 970377

Strand: Reverse

Name: Not Available

Synonym: AF1064

Alternate gene names: 11498669

Gene position: 970377-968515 (Counterclockwise)

Preceding gene: 11498674

Following gene: 11498668

Centisome position: 44.55

GC content: 49.97

Gene sequence:

>1863_bases
ATGATCGCAAAAGTAGTATCTCACGAGTTGCCCAAGCACCGGCACAGGTGGTTTGGAGCGGTTGAGCTCGACAACGGTTT
GACGCTTTACATGTCCGGCATCGCTGCCTGGCTCTTTGAAGGTGATGTTGTTGAGGTTGTAATTAAAAACGAGCCGAAGG
AAATCTACGGGAGAAAAATACTGTTTTTCGCAGATTACGAGCTGTACAAGTTTTACGGGAGTGAGAGGATCAAGGTCTGG
GACGTTTTTTCAAGAAATCTGGAACTTCCGCGATACAGCTTCGGAAAGGAGGTTTACAGATACCGAATCAGGGCGAGAGA
GGCTGTTTACGAAAAGGACTTTGAGAGGATCGCGGAGCTTGAGCAGTACCATTACGCAAGCCAGAAAAGCAAGGTTGCGC
TGTGGAAGTGCTATGACTGCGGTAACCTCATCGAGGCAAACACGAAGCCCGTTTGCGAGTGCGGAAGCAGGAATGTGCAC
ATTGTCGAGATAAAGGGCTCCACTCCAGCTTCGCGATTTTTGATCTTCGAGCTCGTCGAAAGACAGCCATTCGAGCCTGA
GGTTGTTGCGTACGTCCGAGTTGACCCTCCTGTGCCGCTGATGCACAGAAAACTTGACGGAAAGATTGTGGAAAACATCA
GAGAAAGGGTTTTCCCCAAAGAGTGGTTTGAAAACGTCTTCTCCCCAGAAAAAGAGCTTTCGGAATTGTTCAGGAAATTA
AGAAGCCGCTTCTCGCTAAAGGTTGCGAGACACAGGCTATGGGAGGAGGCAAGCGAGGAGGCAATGAAGAAGTGCAACTC
AGCAGCATCGAGAATTGCGAGGGTCGTTGTTCATCCCGACTACAGAGCGGATGGGCTGGGAATTCTTGCAGTCAGGACTG
CAGTTGAGTGGATTGAGGAAAGAAGAGTCCCTGAGATGAGGATGAGAAAGCACCTCGTCGAAACAATTGCCCAGATGGCC
AGGTTCAACCCCTTCTTCGAGAAGGCTGGATTTTACTACCTATGGGATACGGCTTCAGGAAAACCGGTTCTGTACAAGCC
ACTTAGCGAAGAGGCTGAGAGGTACATAAGGAAGTTTCTGGAGGAGGACGAGGTTGCGAGAGGCCACGGGGGAAAACTGT
GTGTTTCAAGATACGGCAGCGTTAAACCTCTTGAGAAATTAAAATTCAGGAATGTCTCGAAGCTCTTTGCAAGCACCCTT
GATCTGGAGAAGGTTAGCGATGAAGTAAGAACCGTCCTTGAGTCCTTCGGAGTCAGGCAGAGGGTGGTGGAAAGATATGT
TCTGAGGGATGTGAATCTGGAGATAAAACCCGGAGAGATTGTTGCCGTCGTCGGTGCTAGCGGTTCTGGAAAAACCACCT
TTCTGAGGTTGATTGTAGGAGAGGCTTTGAAATTGGACGATGATGTGTATAAGCCGAGCAGCGGGATGGTGGAGGTTGTG
GTGGACAGCATAGCTGCGATGATACCGTCCGAACTCGAACCGCAGATAACCGAGAAAAGTATTCTGGAGCAGATATTTGA
CATAACCGGAGATATTCATCTGGCAGTGGAGGTTCTGAACAGGGCGGGAATCTCTGACGCGGTTCTCTACAGAGCAAGGT
TCAACGAGCTCTCAACAGGGCAGAAGGAGAGGTTCAAGCTCGCAGCCTGTCTGGCCAAAAAACCGAGCCTGATGCTTGTG
GACGAGTTTGCCGCCCATCTGGATGAGATGACGGCCGTGAGGGTGGCGAGAAAAATATCAGAGCTCGCAAGGGAGGCGAA
GATAACTCTGATTGCGGTAACTCACAGAAAGGAGGTTATAAACGCTCTCTCTCCGGACAGGATTCTTTACGTGGGTTATG
GTGGGGTTACCGAATCCCCTTAA

Upstream 100 bases:

>100_bases
CCCATTTTTTTTCTCCCCTCACTATCATGGATGCAAAGGGCTCTCTCACAATCAGACCTCTCACGAAAATTGTATAACTT
GGAGGGAAAAATAACTTTTG

Downstream 100 bases:

>100_bases
TAAAACTTCAGCTAGTTCATGAAATGCGAAGAAAAGTTTTTATTTTTTTGGTTGCATCCCAATATAATGACGAAGATACT
CGTCGTTGACGATGATTGCA

Product: ABC transporter, ATP-binding protein, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 620; Mature: 620

Protein sequence:

>620_residues
MIAKVVSHELPKHRHRWFGAVELDNGLTLYMSGIAAWLFEGDVVEVVIKNEPKEIYGRKILFFADYELYKFYGSERIKVW
DVFSRNLELPRYSFGKEVYRYRIRAREAVYEKDFERIAELEQYHYASQKSKVALWKCYDCGNLIEANTKPVCECGSRNVH
IVEIKGSTPASRFLIFELVERQPFEPEVVAYVRVDPPVPLMHRKLDGKIVENIRERVFPKEWFENVFSPEKELSELFRKL
RSRFSLKVARHRLWEEASEEAMKKCNSAASRIARVVVHPDYRADGLGILAVRTAVEWIEERRVPEMRMRKHLVETIAQMA
RFNPFFEKAGFYYLWDTASGKPVLYKPLSEEAERYIRKFLEEDEVARGHGGKLCVSRYGSVKPLEKLKFRNVSKLFASTL
DLEKVSDEVRTVLESFGVRQRVVERYVLRDVNLEIKPGEIVAVVGASGSGKTTFLRLIVGEALKLDDDVYKPSSGMVEVV
VDSIAAMIPSELEPQITEKSILEQIFDITGDIHLAVEVLNRAGISDAVLYRARFNELSTGQKERFKLAACLAKKPSLMLV
DEFAAHLDEMTAVRVARKISELAREAKITLIAVTHRKEVINALSPDRILYVGYGGVTESP

Sequences:

>Translated_620_residues
MIAKVVSHELPKHRHRWFGAVELDNGLTLYMSGIAAWLFEGDVVEVVIKNEPKEIYGRKILFFADYELYKFYGSERIKVW
DVFSRNLELPRYSFGKEVYRYRIRAREAVYEKDFERIAELEQYHYASQKSKVALWKCYDCGNLIEANTKPVCECGSRNVH
IVEIKGSTPASRFLIFELVERQPFEPEVVAYVRVDPPVPLMHRKLDGKIVENIRERVFPKEWFENVFSPEKELSELFRKL
RSRFSLKVARHRLWEEASEEAMKKCNSAASRIARVVVHPDYRADGLGILAVRTAVEWIEERRVPEMRMRKHLVETIAQMA
RFNPFFEKAGFYYLWDTASGKPVLYKPLSEEAERYIRKFLEEDEVARGHGGKLCVSRYGSVKPLEKLKFRNVSKLFASTL
DLEKVSDEVRTVLESFGVRQRVVERYVLRDVNLEIKPGEIVAVVGASGSGKTTFLRLIVGEALKLDDDVYKPSSGMVEVV
VDSIAAMIPSELEPQITEKSILEQIFDITGDIHLAVEVLNRAGISDAVLYRARFNELSTGQKERFKLAACLAKKPSLMLV
DEFAAHLDEMTAVRVARKISELAREAKITLIAVTHRKEVINALSPDRILYVGYGGVTESP
>Mature_620_residues
MIAKVVSHELPKHRHRWFGAVELDNGLTLYMSGIAAWLFEGDVVEVVIKNEPKEIYGRKILFFADYELYKFYGSERIKVW
DVFSRNLELPRYSFGKEVYRYRIRAREAVYEKDFERIAELEQYHYASQKSKVALWKCYDCGNLIEANTKPVCECGSRNVH
IVEIKGSTPASRFLIFELVERQPFEPEVVAYVRVDPPVPLMHRKLDGKIVENIRERVFPKEWFENVFSPEKELSELFRKL
RSRFSLKVARHRLWEEASEEAMKKCNSAASRIARVVVHPDYRADGLGILAVRTAVEWIEERRVPEMRMRKHLVETIAQMA
RFNPFFEKAGFYYLWDTASGKPVLYKPLSEEAERYIRKFLEEDEVARGHGGKLCVSRYGSVKPLEKLKFRNVSKLFASTL
DLEKVSDEVRTVLESFGVRQRVVERYVLRDVNLEIKPGEIVAVVGASGSGKTTFLRLIVGEALKLDDDVYKPSSGMVEVV
VDSIAAMIPSELEPQITEKSILEQIFDITGDIHLAVEVLNRAGISDAVLYRARFNELSTGQKERFKLAACLAKKPSLMLV
DEFAAHLDEMTAVRVARKISELAREAKITLIAVTHRKEVINALSPDRILYVGYGGVTESP

Specific function: Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system [H]

COG id: COG2401

COG function: function code R; ABC-type ATPase fused to a predicted acetyltransferase domain

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI11967969, Length=227, Percent_Identity=28.1938325991189, Blast_Score=70, Evalue=7e-12,
Organism=Homo sapiens, GI108773784, Length=218, Percent_Identity=27.9816513761468, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI108773782, Length=218, Percent_Identity=27.9816513761468, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1787164, Length=205, Percent_Identity=32.1951219512195, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI87081791, Length=207, Percent_Identity=28.0193236714976, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786698, Length=190, Percent_Identity=25.7894736842105, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1786398, Length=194, Percent_Identity=25.7731958762887, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788165, Length=220, Percent_Identity=26.3636363636364, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87082267, Length=200, Percent_Identity=28.5, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1787370, Length=233, Percent_Identity=27.4678111587983, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1788506, Length=214, Percent_Identity=27.5700934579439, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI193209708, Length=256, Percent_Identity=27.734375, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193208177, Length=245, Percent_Identity=27.3469387755102, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193202349, Length=216, Percent_Identity=31.4814814814815, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017908
- InterPro:   IPR003593
- InterPro:   IPR018449 [H]

Pfam domain/function: PF00005 ABC_tran; PF09383 NIL [H]

EC number: NA

Molecular weight: Translated: 71201; Mature: 71201

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAKVVSHELPKHRHRWFGAVELDNGLTLYMSGIAAWLFEGDVVEVVIKNEPKEIYGRKI
CCHHHHHHHCCHHHHHHEEEEEECCCCEEHHHHHHHHHCCCCEEEEEECCCCHHHHCCEE
LFFADYELYKFYGSERIKVWDVFSRNLELPRYSFGKEVYRYRIRAREAVYEKDFERIAEL
EEEECHHHHHHHCCCCEEEEEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQYHYASQKSKVALWKCYDCGNLIEANTKPVCECGSRNVHIVEIKGSTPASRFLIFELVE
HHHHHHCCCCCEEEEEEECCCCCCCCCCCCHHHCCCCCEEEEEEECCCCHHHHHHHHHHH
RQPFEPEVVAYVRVDPPVPLMHRKLDGKIVENIRERVFPKEWFENVFSPEKELSELFRKL
CCCCCCCEEEEEEECCCCCHHHHHCCHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHH
RSRFSLKVARHRLWEEASEEAMKKCNSAASRIARVVVHPDYRADGLGILAVRTAVEWIEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHH
RRVPEMRMRKHLVETIAQMARFNPFFEKAGFYYLWDTASGKPVLYKPLSEEAERYIRKFL
CCCHHHHHHHHHHHHHHHHHHCCHHHHHCCEEEEEECCCCCEEEECCHHHHHHHHHHHHH
EEDEVARGHGGKLCVSRYGSVKPLEKLKFRNVSKLFASTLDLEKVSDEVRTVLESFGVRQ
CCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
RVVERYVLRDVNLEIKPGEIVAVVGASGSGKTTFLRLIVGEALKLDDDVYKPSSGMVEVV
HHHHHHHHHHCCEEECCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
VDSIAAMIPSELEPQITEKSILEQIFDITGDIHLAVEVLNRAGISDAVLYRARFNELSTG
HHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
QKERFKLAACLAKKPSLMLVDEFAAHLDEMTAVRVARKISELAREAKITLIAVTHRKEVI
HHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECHHHHH
NALSPDRILYVGYGGVTESP
HHCCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MIAKVVSHELPKHRHRWFGAVELDNGLTLYMSGIAAWLFEGDVVEVVIKNEPKEIYGRKI
CCHHHHHHHCCHHHHHHEEEEEECCCCEEHHHHHHHHHCCCCEEEEEECCCCHHHHCCEE
LFFADYELYKFYGSERIKVWDVFSRNLELPRYSFGKEVYRYRIRAREAVYEKDFERIAEL
EEEECHHHHHHHCCCCEEEEEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQYHYASQKSKVALWKCYDCGNLIEANTKPVCECGSRNVHIVEIKGSTPASRFLIFELVE
HHHHHHCCCCCEEEEEEECCCCCCCCCCCCHHHCCCCCEEEEEEECCCCHHHHHHHHHHH
RQPFEPEVVAYVRVDPPVPLMHRKLDGKIVENIRERVFPKEWFENVFSPEKELSELFRKL
CCCCCCCEEEEEEECCCCCHHHHHCCHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHH
RSRFSLKVARHRLWEEASEEAMKKCNSAASRIARVVVHPDYRADGLGILAVRTAVEWIEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHH
RRVPEMRMRKHLVETIAQMARFNPFFEKAGFYYLWDTASGKPVLYKPLSEEAERYIRKFL
CCCHHHHHHHHHHHHHHHHHHCCHHHHHCCEEEEEECCCCCEEEECCHHHHHHHHHHHHH
EEDEVARGHGGKLCVSRYGSVKPLEKLKFRNVSKLFASTLDLEKVSDEVRTVLESFGVRQ
CCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
RVVERYVLRDVNLEIKPGEIVAVVGASGSGKTTFLRLIVGEALKLDDDVYKPSSGMVEVV
HHHHHHHHHHCCEEECCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
VDSIAAMIPSELEPQITEKSILEQIFDITGDIHLAVEVLNRAGISDAVLYRARFNELSTG
HHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
QKERFKLAACLAKKPSLMLVDEFAAHLDEMTAVRVARKISELAREAKITLIAVTHRKEVI
HHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECHHHHH
NALSPDRILYVGYGGVTESP
HHCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12840036 [H]