Click here to switch to the map view.

The map label for this gene is tlpC-1

Identifier: 11498639

GI number: 11498639

Start: 940088

End: 942121

Strand: Reverse

Name: tlpC-1

Synonym: AF1034

Alternate gene names: 11498639

Gene position: 942121-940088 (Counterclockwise)

Preceding gene: 11498640

Following gene: 11498634

Centisome position: 43.25

GC content: 51.23

Gene sequence:

>2034_bases
ATGGTAGGTGAGGCTCAAAATGACTGCGAAAAGCTTCTGGAGAGAATTAACCAGCTGGAAGAACAGCTAAGGCAAAAAGA
CGAAGAGTTGAAGCAGAAGGACGCCTTTATAGAGGCCTTGATCAGGAGTGTGCCGAAGCCGGTATTTTTCTACTTCATCG
ATGCCGAGGGGAAGCTGAGGTACGTAAACGACTACAATCTGGAGTTTTACGGAAAGAGCAGGGAGGAGGTAATAGGAAAG
AGGCCTTCAGAGCTTTTCTTAGACCCTACAGGGCAAAAAACGCTTGCAGAGGTTGGAATGAAGACTATGATTGAGACGGC
GCTGGAGAAAGGGGGGCTGAAGATTGAAAATCAGGAGGTAAAGCTCGGGACAGAGAAAGGATTGATGCACATCCTCACAT
CCTGCGCGCCGGTTAAGGTAAACGGAGAGCTTGTGGGGATGGTTGGGTTCTACGTTGATGTAACACCCATCAAGCAGAAG
GAGGAGGAGGCAAAGAAGGCCTATGAGCTGGTAAAAGAGGTCTTCAAGAACATGCCCTTCCCGGCTTACGTCCTCTTCGT
CAACAGAGACCACAAGATTCAGTATGCCAACGATGAGATTGCCAAGCTTGCGGGATACAGCAGTGCTGAGGAGATAATCG
GCCTGCCTCCGAGCGAACTCTTCAAAACGGAGGGAGGCAGAACAGTTGCAGACAAGGTCCTCGATACCGGAAAGGCTGTA
ATCAACCACCAGGCTGTAACGCGCACGAAGGACGGGAGAGAAGTGCCGGTTCTCGTTTCATGCATCCCGGTTTACGTTGA
CGGAGAGATGGTCGGCGTCATCGACCTCTTTACCGACATCACAGAGCTCAGGGAGAAAGAAAAAGAAATCGAAGAAATGC
TCGCCTACACCGGCAGATGCCTCAACATGCTCAGCAACGGAATCAGAGAGCTGCAGGCAGGAAACCTCGACGTCAGGCTT
GAAAAAATCAGGGACGACGAGTTCGGAGAGACGTTCGAGGCTTTCAACGAGTTCGCGGGAAGAATGCAGGAAATTGTAAG
GAAGCTTGCCGATGACATGAAGGAAACTGCCAACCAAGTTAGGGAAGCTGCAGAAGCAGTAAACCAGATGAACGCTGGAA
TGCAGCAGATAAGCTCAGCCTCGCAGCAAATAGCAACGGGAAGCGAGAACCTATCAAGGCTGGCAAACGCCTCAACACTC
GACCTCAAGGCTGCTGAGGAGATATTCAGAGAGCTTGCGGCAAAGGCTGATGAGTCGAACAGACAGGTCGAGGCTGCTGC
AGAAAGATCTAGGATAGCGGAGCAGGAGGGAGGAAGAGCCCTCGAAATCATCAAGAGCATAGTCCAGGAGGTAGAGAACG
CATCAAAAGTCGTCGAAACCCTTGAGCAGGCGGTAAGAAACATAGGCAAGGTAACTGAAAGAATAAAATCAATAGCAGAT
CAAACAAACCTCCTCGCCCTCAATGCAGCTATCGAAGCGGCAAGAGCTGGAGAGCACGGAAGAGGCTTTGCTGTTGTTGC
TGATGAGGTTAGAAAGCTCGCTGAAGAGTCGAGAAAGAGCACTGAGGAGATAGACGAGATAGTCAGGAACGTGCAGGAAG
AAACGAGAAAGGTAATCGAGGCAACGAACAAGGTTAAGGAGAGCAGCCTGCAGGGGAGCGAGGGGATAGAGGCGGCAATT
AAGCAGGCTGGAGAAATCTTAGGGGCGATTAACAGGATAAACGACATGGTAAAAGCTGTGGCATCTAAGGCAGAAGAAGG
CCTCGCGAAGATAGAGCAGCTCGCCAGAAACTTCGAGGAGGTGGCATCAACAGCAGAAGAAAACGCAGCGAGCAGCGAGG
AAACCTCAGCAGCCATCGAAGAGCAGACGGCAGCAGTCCAGCAGGTCAGCATCGCAATGGAGAAGGTCAACGAGATAGCC
AACGCAACCCTGCAAACCATCATCGAGAACTTCAGAATCTTCGACGCTCTCGGCCAGGACATCTCCGCCAGCTATGCAAA
GACGATGACAGACGGTGGCAGGAGAGTTCGTTAG

Upstream 100 bases:

>100_bases
TTCAAAACTGAAATTATTAGTTGACATTTTCTCAATTATAACTTCAAACATAGAAGAATTTTTTATATAGCTCTTCTCAA
AAGAATTTCTCGGTGGTGGT

Downstream 100 bases:

>100_bases
TTTTTAATTTTATTTAACTGAATTCTCAGCCCTCCAGCACGTCCCTCCCCCTTTTCAGCAGAAAGGCGTACTTGGGGTCG
GTGGCTGAGAGCATCGCGCT

Product: methyl-accepting chemotaxis protein (tlpC-1)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 677; Mature: 677

Protein sequence:

>677_residues
MVGEAQNDCEKLLERINQLEEQLRQKDEELKQKDAFIEALIRSVPKPVFFYFIDAEGKLRYVNDYNLEFYGKSREEVIGK
RPSELFLDPTGQKTLAEVGMKTMIETALEKGGLKIENQEVKLGTEKGLMHILTSCAPVKVNGELVGMVGFYVDVTPIKQK
EEEAKKAYELVKEVFKNMPFPAYVLFVNRDHKIQYANDEIAKLAGYSSAEEIIGLPPSELFKTEGGRTVADKVLDTGKAV
INHQAVTRTKDGREVPVLVSCIPVYVDGEMVGVIDLFTDITELREKEKEIEEMLAYTGRCLNMLSNGIRELQAGNLDVRL
EKIRDDEFGETFEAFNEFAGRMQEIVRKLADDMKETANQVREAAEAVNQMNAGMQQISSASQQIATGSENLSRLANASTL
DLKAAEEIFRELAAKADESNRQVEAAAERSRIAEQEGGRALEIIKSIVQEVENASKVVETLEQAVRNIGKVTERIKSIAD
QTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAEESRKSTEEIDEIVRNVQEETRKVIEATNKVKESSLQGSEGIEAAI
KQAGEILGAINRINDMVKAVASKAEEGLAKIEQLARNFEEVASTAEENAASSEETSAAIEEQTAAVQQVSIAMEKVNEIA
NATLQTIIENFRIFDALGQDISASYAKTMTDGGRRVR

Sequences:

>Translated_677_residues
MVGEAQNDCEKLLERINQLEEQLRQKDEELKQKDAFIEALIRSVPKPVFFYFIDAEGKLRYVNDYNLEFYGKSREEVIGK
RPSELFLDPTGQKTLAEVGMKTMIETALEKGGLKIENQEVKLGTEKGLMHILTSCAPVKVNGELVGMVGFYVDVTPIKQK
EEEAKKAYELVKEVFKNMPFPAYVLFVNRDHKIQYANDEIAKLAGYSSAEEIIGLPPSELFKTEGGRTVADKVLDTGKAV
INHQAVTRTKDGREVPVLVSCIPVYVDGEMVGVIDLFTDITELREKEKEIEEMLAYTGRCLNMLSNGIRELQAGNLDVRL
EKIRDDEFGETFEAFNEFAGRMQEIVRKLADDMKETANQVREAAEAVNQMNAGMQQISSASQQIATGSENLSRLANASTL
DLKAAEEIFRELAAKADESNRQVEAAAERSRIAEQEGGRALEIIKSIVQEVENASKVVETLEQAVRNIGKVTERIKSIAD
QTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAEESRKSTEEIDEIVRNVQEETRKVIEATNKVKESSLQGSEGIEAAI
KQAGEILGAINRINDMVKAVASKAEEGLAKIEQLARNFEEVASTAEENAASSEETSAAIEEQTAAVQQVSIAMEKVNEIA
NATLQTIIENFRIFDALGQDISASYAKTMTDGGRRVR
>Mature_677_residues
MVGEAQNDCEKLLERINQLEEQLRQKDEELKQKDAFIEALIRSVPKPVFFYFIDAEGKLRYVNDYNLEFYGKSREEVIGK
RPSELFLDPTGQKTLAEVGMKTMIETALEKGGLKIENQEVKLGTEKGLMHILTSCAPVKVNGELVGMVGFYVDVTPIKQK
EEEAKKAYELVKEVFKNMPFPAYVLFVNRDHKIQYANDEIAKLAGYSSAEEIIGLPPSELFKTEGGRTVADKVLDTGKAV
INHQAVTRTKDGREVPVLVSCIPVYVDGEMVGVIDLFTDITELREKEKEIEEMLAYTGRCLNMLSNGIRELQAGNLDVRL
EKIRDDEFGETFEAFNEFAGRMQEIVRKLADDMKETANQVREAAEAVNQMNAGMQQISSASQQIATGSENLSRLANASTL
DLKAAEEIFRELAAKADESNRQVEAAAERSRIAEQEGGRALEIIKSIVQEVENASKVVETLEQAVRNIGKVTERIKSIAD
QTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAEESRKSTEEIDEIVRNVQEETRKVIEATNKVKESSLQGSEGIEAAI
KQAGEILGAINRINDMVKAVASKAEEGLAKIEQLARNFEEVASTAEENAASSEETSAAIEEQTAAVQQVSIAMEKVNEIA
NATLQTIIENFRIFDALGQDISASYAKTMTDGGRRVR

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=338, Percent_Identity=28.9940828402367, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI1788195, Length=305, Percent_Identity=29.8360655737705, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI2367378, Length=315, Percent_Identity=30.7936507936508, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1787690, Length=324, Percent_Identity=30.5555555555556, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1789453, Length=294, Percent_Identity=26.8707482993197, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 74913; Mature: 74913

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50113 PAC ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGEAQNDCEKLLERINQLEEQLRQKDEELKQKDAFIEALIRSVPKPVFFYFIDAEGKLR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEE
YVNDYNLEFYGKSREEVIGKRPSELFLDPTGQKTLAEVGMKTMIETALEKGGLKIENQEV
EEECCCEEEECCCHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCE
KLGTEKGLMHILTSCAPVKVNGELVGMVGFYVDVTPIKQKEEEAKKAYELVKEVFKNMPF
ECCHHHHHHHHHHCCCCEEECCEEEEEEHHHEECCCCHHHHHHHHHHHHHHHHHHHCCCC
PAYVLFVNRDHKIQYANDEIAKLAGYSSAEEIIGLPPSELFKTEGGRTVADKVLDTGKAV
CEEEEEEECCCEEEECCHHHHHHHCCCCHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHH
INHQAVTRTKDGREVPVLVSCIPVYVDGEMVGVIDLFTDITELREKEKEIEEMLAYTGRC
HHHHHHHCCCCCCCCCHHEEHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNMLSNGIRELQAGNLDVRLEKIRDDEFGETFEAFNEFAGRMQEIVRKLADDMKETANQV
HHHHHHHHHHHHCCCCCEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REAAEAVNQMNAGMQQISSASQQIATGSENLSRLANASTLDLKAAEEIFRELAAKADESN
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
RQVEAAAERSRIAEQEGGRALEIIKSIVQEVENASKVVETLEQAVRNIGKVTERIKSIAD
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAEESRKSTEEIDEIVRNVQEETRKVIE
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATNKVKESSLQGSEGIEAAIKQAGEILGAINRINDMVKAVASKAEEGLAKIEQLARNFEE
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VASTAEENAASSEETSAAIEEQTAAVQQVSIAMEKVNEIANATLQTIIENFRIFDALGQD
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
ISASYAKTMTDGGRRVR
HHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MVGEAQNDCEKLLERINQLEEQLRQKDEELKQKDAFIEALIRSVPKPVFFYFIDAEGKLR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEE
YVNDYNLEFYGKSREEVIGKRPSELFLDPTGQKTLAEVGMKTMIETALEKGGLKIENQEV
EEECCCEEEECCCHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCE
KLGTEKGLMHILTSCAPVKVNGELVGMVGFYVDVTPIKQKEEEAKKAYELVKEVFKNMPF
ECCHHHHHHHHHHCCCCEEECCEEEEEEHHHEECCCCHHHHHHHHHHHHHHHHHHHCCCC
PAYVLFVNRDHKIQYANDEIAKLAGYSSAEEIIGLPPSELFKTEGGRTVADKVLDTGKAV
CEEEEEEECCCEEEECCHHHHHHHCCCCHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHH
INHQAVTRTKDGREVPVLVSCIPVYVDGEMVGVIDLFTDITELREKEKEIEEMLAYTGRC
HHHHHHHCCCCCCCCCHHEEHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNMLSNGIRELQAGNLDVRLEKIRDDEFGETFEAFNEFAGRMQEIVRKLADDMKETANQV
HHHHHHHHHHHHCCCCCEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REAAEAVNQMNAGMQQISSASQQIATGSENLSRLANASTLDLKAAEEIFRELAAKADESN
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
RQVEAAAERSRIAEQEGGRALEIIKSIVQEVENASKVVETLEQAVRNIGKVTERIKSIAD
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAEESRKSTEEIDEIVRNVQEETRKVIE
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATNKVKESSLQGSEGIEAAIKQAGEILGAINRINDMVKAVASKAEEGLAKIEQLARNFEE
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VASTAEENAASSEETSAAIEEQTAAVQQVSIAMEKVNEIANATLQTIIENFRIFDALGQD
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
ISASYAKTMTDGGRRVR
HHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA