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The map label for this gene is putP-2

Identifier: 11498574

GI number: 11498574

Start: 868965

End: 870560

Strand: Reverse

Name: putP-2

Synonym: AF0969

Alternate gene names: 11498574

Gene position: 870560-868965 (Counterclockwise)

Preceding gene: 11498575

Following gene: 11498573

Centisome position: 39.96

GC content: 52.13

Gene sequence:

>1596_bases
ATGGCTCAGGTGGAGGCACCGGTCATAGGAATTACAGTGCTGTACTTCCTGGCCATAATTATAATAGGATACTATTCGAG
GCAAAGGCTGAAGAGCGCTACAGACTACTACGTTGCTGGAAGGCAGGTTGGCGCTGTTGTTAACGGTCTTGCACTGGAAT
CTACTTACCTGAGCCCTGCTTCGATGCTCGGACTACCGGCATACATCTTCATCCTCGGCTACCCCTTCTGGTGGGCGATG
TCGGCCATAATTGCTGGAATGCCCATTGCAACTCTGCTGACAGCATCAGCACTGAGAAAGTACGCACCAACAAGCTTTGC
TGACTACTACGCTGACAGGTACAACGACCAGAGGCTCAGATGGCTTGTGGGTATAGTTACAGTGATTGGTGCGGTGCTCT
ACATAACGCTCTCGCTTGTGGGTATGGCCCTCTTCCTGTTAGCTGTCGCAAAAGTGCCCTACATCATTGGACTGATAGTT
GGAACGATTATAGTGATGCTCTACGTTGTGTGGGGCGGAATGATAGCAACGAGCTGGAACGCTGCCTTCCAGGCGTTCCT
GATGACTGTTGCTGCAGTTATTGCTGCTGCAGTAATTGTTATCAAGCTCGGAGGACTTGGAGGATTTTACGAGGCTGTTT
TGGCCAACAATCCCAAGTTCTGGAACACCCCGAGCGACCCTGAGCCACCCCACCTCCTCAGCGGAACGTGGATTGCAGTT
ATTGGCTGGTTCTTCGTCTGGCACTACGGATTCGCAACGATGCCCTACACCGTCGTGAGGTTCTTCACAACCATGGACAT
CAAGACCGCAAGAAGAAGCATTTTCTGGTGCACTCTCGCTGCAGGCATTTTCTACATGGCTCTGGAAATTATCGGTGCTG
CCTCAAAGCTTATGATTGAAACAGGCCCGATGGGAGGAGAGGGAGCCAATGCGGTCAAAATCCTTCAGAGCTACATGGCC
CAGTATGGAGTTGGAGGGTGGACTGACTACTCAATGATTGCAGCAGTTGAGGCCTTACAGAATCCATGGGTTCTCGGTAT
CCTCTGTGCTGGCGGTTTAGCAATTGCAATGTCAACTGCAGCAGGATGGGTTATGGTTGTCAACACTCTTCTGACAAGGG
ACTGGGGAGACATGCTTCTGAAGAGCAAGTTTGCTAAGGAGAAGCCGGTGACTCTGGCCAGGATAATCTCAGTAATATTC
CTGATCGTGGGATTCCTCGTTGCCATCAACCCGCCGGGACTTGTGCTTGACCTGTCAGGATGGGCATTCGTCGTCATCAT
CTCCGCCCTCGGTCCAGGACTTGTGCTGGGACTGTGGTGGAAGAGGGCAACGAGAGCGGCGATGTGGACAACAGCAATAG
TCATGACCCCACTGCACCTCTACGCATGGCTGAAGGCAAAGCTCGTGCTCGGGCATCATGCCTTCTTCTTCCTCAACGAC
GTGCTGTTTGGCAACGCAAAGGCCCTGATTACGCCACACCAAGTCTGGGCAATTCCAGTGGGCTTCCTGCTGTTCATCAT
CGTGTCTCTCATAACCAAGCCCGTTGAGGAGGAGGCTGTACAGAAGTACTGCGTTGAGCTGACCAAGGAGGTTTAA

Upstream 100 bases:

>100_bases
GGTACGCGTCGTTCCTAGGGACGTTCTTGATACCGCTGTTCATGTCGATAATATACTTCTACTTCCCGGAGAAGGCTGAA
GAAGCGAGAGGTGGTTCGTA

Downstream 100 bases:

>100_bases
ATTTTTATTTTTATATTTTTGTTTTTAACACGCTGTTTTTAGCGTACTGTATTTAGCTTTAATGTCAATAATTAATTACG
AGAGCAAATGAAAAATCTAA

Product: proline permease (putP-2)

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 531; Mature: 530

Protein sequence:

>531_residues
MAQVEAPVIGITVLYFLAIIIIGYYSRQRLKSATDYYVAGRQVGAVVNGLALESTYLSPASMLGLPAYIFILGYPFWWAM
SAIIAGMPIATLLTASALRKYAPTSFADYYADRYNDQRLRWLVGIVTVIGAVLYITLSLVGMALFLLAVAKVPYIIGLIV
GTIIVMLYVVWGGMIATSWNAAFQAFLMTVAAVIAAAVIVIKLGGLGGFYEAVLANNPKFWNTPSDPEPPHLLSGTWIAV
IGWFFVWHYGFATMPYTVVRFFTTMDIKTARRSIFWCTLAAGIFYMALEIIGAASKLMIETGPMGGEGANAVKILQSYMA
QYGVGGWTDYSMIAAVEALQNPWVLGILCAGGLAIAMSTAAGWVMVVNTLLTRDWGDMLLKSKFAKEKPVTLARIISVIF
LIVGFLVAINPPGLVLDLSGWAFVVIISALGPGLVLGLWWKRATRAAMWTTAIVMTPLHLYAWLKAKLVLGHHAFFFLND
VLFGNAKALITPHQVWAIPVGFLLFIIVSLITKPVEEEAVQKYCVELTKEV

Sequences:

>Translated_531_residues
MAQVEAPVIGITVLYFLAIIIIGYYSRQRLKSATDYYVAGRQVGAVVNGLALESTYLSPASMLGLPAYIFILGYPFWWAM
SAIIAGMPIATLLTASALRKYAPTSFADYYADRYNDQRLRWLVGIVTVIGAVLYITLSLVGMALFLLAVAKVPYIIGLIV
GTIIVMLYVVWGGMIATSWNAAFQAFLMTVAAVIAAAVIVIKLGGLGGFYEAVLANNPKFWNTPSDPEPPHLLSGTWIAV
IGWFFVWHYGFATMPYTVVRFFTTMDIKTARRSIFWCTLAAGIFYMALEIIGAASKLMIETGPMGGEGANAVKILQSYMA
QYGVGGWTDYSMIAAVEALQNPWVLGILCAGGLAIAMSTAAGWVMVVNTLLTRDWGDMLLKSKFAKEKPVTLARIISVIF
LIVGFLVAINPPGLVLDLSGWAFVVIISALGPGLVLGLWWKRATRAAMWTTAIVMTPLHLYAWLKAKLVLGHHAFFFLND
VLFGNAKALITPHQVWAIPVGFLLFIIVSLITKPVEEEAVQKYCVELTKEV
>Mature_530_residues
AQVEAPVIGITVLYFLAIIIIGYYSRQRLKSATDYYVAGRQVGAVVNGLALESTYLSPASMLGLPAYIFILGYPFWWAMS
AIIAGMPIATLLTASALRKYAPTSFADYYADRYNDQRLRWLVGIVTVIGAVLYITLSLVGMALFLLAVAKVPYIIGLIVG
TIIVMLYVVWGGMIATSWNAAFQAFLMTVAAVIAAAVIVIKLGGLGGFYEAVLANNPKFWNTPSDPEPPHLLSGTWIAVI
GWFFVWHYGFATMPYTVVRFFTTMDIKTARRSIFWCTLAAGIFYMALEIIGAASKLMIETGPMGGEGANAVKILQSYMAQ
YGVGGWTDYSMIAAVEALQNPWVLGILCAGGLAIAMSTAAGWVMVVNTLLTRDWGDMLLKSKFAKEKPVTLARIISVIFL
IVGFLVAINPPGLVLDLSGWAFVVIISALGPGLVLGLWWKRATRAAMWTTAIVMTPLHLYAWLKAKLVLGHHAFFFLNDV
LFGNAKALITPHQVWAIPVGFLLFIIVSLITKPVEEEAVQKYCVELTKEV

Specific function: Transports acetate [H]

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=534, Percent_Identity=26.7790262172285, Blast_Score=129, Evalue=6e-30,
Organism=Escherichia coli, GI1790503, Length=468, Percent_Identity=25.8547008547009, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1787251, Length=453, Percent_Identity=25.1655629139073, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI87082237, Length=461, Percent_Identity=24.0780911062907, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28573698, Length=446, Percent_Identity=23.542600896861, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI28574994, Length=395, Percent_Identity=22.5316455696203, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 57976; Mature: 57845

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AQVEAPVIGITVLYFLAIIIIGYYSRQRLKSATDYYVAGRQVGAVVNGLALESTYLSPA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHH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HHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA