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Identifier: 11498533

GI number: 11498533

Start: 827854

End: 828486

Strand: Reverse

Name: Not Available

Synonym: AF0928

Alternate gene names: 11498533

Gene position: 828486-827854 (Counterclockwise)

Preceding gene: 11498534

Following gene: 11498532

Centisome position: 38.03

GC content: 49.76

Gene sequence:

>633_bases
ATGCATCAGGTAATCCAGCAGAGGAAGCCAGAAAGCTCAGGAGAGTCCTCAAGATTTGAGCTAATTGCCTTCGACCTTGA
CGGAACTCTTATCGAGCTCAACATCCCCTTTGATGAGATAAGGAGAGAGCTTGGAATTGAGGGGAGGTTCATCCTTGAGT
CCATAATGGATGAGAAGGACCTTCAGAGAAGGCAGGAAATGCTCAGAGTTCTTGAGAGCTATGAGCTTAGGTGTGCGATG
GAGGCAAGGCCAGCCTACTACGCCGTTGAGCTCGTTAACGGCCTTGATGCCATAAAAGGAGTCATTACAAGGAACAGCAG
AAGAAGTGCGGAAATAGTTGCCGAGAGGCTCGGCTTCGAGTTCGATTTTATCATCGGAAGGGAAGATGCCGAGCCAAAAC
CCTCTCCTGAGCCCTTGAACCTCGCCTTGAGGATGTTTGACGTCAGCCCCTCAAAGGCTTTGATGGTTGGAGACTTTCTT
TTCGACTTGCTATCGGGAAAGGCGGCGGGAGCAAAAACCGCCCTGATACTGACAGATAGAAACAGGGGGATGGCAAAGTC
TTTTATCCAGCACGCAGACTACGTTTTTGAGTCCCTGAAAGAGCTGGCAGATTTCCTTGAGGTGGAGCAATGA

Upstream 100 bases:

>100_bases
GCGGGGGATATGGAGATACTCTGCCCGGGAATTGGGGCACAGAAAGGCAGCATCGAAGCTGTGAAGTATGCTGATGGAAT
TATAGTGGGGAGGGGAATTT

Downstream 100 bases:

>100_bases
AGGAGATACCGAAAAGCCATCCGAGATACGCGTCGCTGGTAACAAGGGAGAAGCTTGTCGAGGGAGTTGAGCTGGGAGTT
ACTGCGATGCCAGGGATTGA

Product: hypothetical protein

Products: NA

Alternate protein names: PGP 2; PGPase2 [H]

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MHQVIQQRKPESSGESSRFELIAFDLDGTLIELNIPFDEIRRELGIEGRFILESIMDEKDLQRRQEMLRVLESYELRCAM
EARPAYYAVELVNGLDAIKGVITRNSRRSAEIVAERLGFEFDFIIGREDAEPKPSPEPLNLALRMFDVSPSKALMVGDFL
FDLLSGKAAGAKTALILTDRNRGMAKSFIQHADYVFESLKELADFLEVEQ

Sequences:

>Translated_210_residues
MHQVIQQRKPESSGESSRFELIAFDLDGTLIELNIPFDEIRRELGIEGRFILESIMDEKDLQRRQEMLRVLESYELRCAM
EARPAYYAVELVNGLDAIKGVITRNSRRSAEIVAERLGFEFDFIIGREDAEPKPSPEPLNLALRMFDVSPSKALMVGDFL
FDLLSGKAAGAKTALILTDRNRGMAKSFIQHADYVFESLKELADFLEVEQ
>Mature_210_residues
MHQVIQQRKPESSGESSRFELIAFDLDGTLIELNIPFDEIRRELGIEGRFILESIMDEKDLQRRQEMLRVLESYELRCAM
EARPAYYAVELVNGLDAIKGVITRNSRRSAEIVAERLGFEFDFIIGREDAEPKPSPEPLNLALRMFDVSPSKALMVGDFL
FDLLSGKAAGAKTALILTDRNRGMAKSFIQHADYVFESLKELADFLEVEQ

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6324705, Length=205, Percent_Identity=27.3170731707317, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 23905; Mature: 23905

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHQVIQQRKPESSGESSRFELIAFDLDGTLIELNIPFDEIRRELGIEGRFILESIMDEKD
CCCHHHHCCCCCCCCCCCEEEEEEECCCEEEEEECCHHHHHHHHCCCCHHHHHHHHCHHH
LQRRQEMLRVLESYELRCAMEARPAYYAVELVNGLDAIKGVITRNSRRSAEIVAERLGFE
HHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCE
FDFIIGREDAEPKPSPEPLNLALRMFDVSPSKALMVGDFLFDLLSGKAAGAKTALILTDR
EEEEEECCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECC
NRGMAKSFIQHADYVFESLKELADFLEVEQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHQVIQQRKPESSGESSRFELIAFDLDGTLIELNIPFDEIRRELGIEGRFILESIMDEKD
CCCHHHHCCCCCCCCCCCEEEEEEECCCEEEEEECCHHHHHHHHCCCCHHHHHHHHCHHH
LQRRQEMLRVLESYELRCAMEARPAYYAVELVNGLDAIKGVITRNSRRSAEIVAERLGFE
HHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCE
FDFIIGREDAEPKPSPEPLNLALRMFDVSPSKALMVGDFLFDLLSGKAAGAKTALILTDR
EEEEEECCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECC
NRGMAKSFIQHADYVFESLKELADFLEVEQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]