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The map label for this gene is dapB

Identifier: 11498514

GI number: 11498514

Start: 813248

End: 814021

Strand: Reverse

Name: dapB

Synonym: AF0909

Alternate gene names: 11498514

Gene position: 814021-813248 (Counterclockwise)

Preceding gene: 11498515

Following gene: 11498512

Centisome position: 37.37

GC content: 51.55

Gene sequence:

>774_bases
ATGCGAGTTGCGGTTTCCGGGGCAGCGGGCAGAATGGGCAGGCTTGTTGTTAAAAATGCAGTGGCAGAGGGCTTGAAGGT
CGTTCAGGCTTTCGACATCAACGAAGTTGGAAAGGATGCGGGAGAACTTGCTGGAGTTGGAAAGATTGGTGTTCCGATTG
AGGACGACATCTCAAAGCTTGATGCTGATGTGCTGATTGACTTCACCACAGCAGAGGCTGCAATGAAGAACGCTGAGGTT
GCTGCGGAGAAGGGAGTGAGGGTGGTGATGGGGACAACAGGCTTCACTGACGAGGACAGGAAGAGGCTTGCAGAGCTGGC
GGAGAAGGTTCCGATGATTGTTTCGCCAAACTTCAGCCTCGGTGTCAACATTTTCTGGAAAATTGTTGAATACGCCGCAA
AAATGCTCTACGAGTGGGATGCAGAGATTGTGGAGCTTCACCACAGGCACAAGCGTGACTCTCCGAGCGGAACTGCCCTG
AAGCTTGCTGAGATCATAAGGAAGGTTAAGGAGGAAAAGGGAATAGAAGCAGACCTAAAGACGTGCAGAGAGGGAATTTC
GCCGAGGGAAAGCGAGATTGGTGTTTTTGGTATTAGAGGAGGAGACGTCGTTGGAGAGCATACAGTCTTCTTCTTCGGAA
GCGGGGAGAGGATTGAGCTTACACACAGGGCGATGAGCAGAGAGTGCTTTGCGATTGGGGCAGTTAGGGCTGCGAAGTGG
ATTGCAAAGGTTGACAAGCCCGGCTTTTACACCATGGACGACTTTTTGGAGTGA

Upstream 100 bases:

>100_bases
GTCGAGCTCTCTGAAGAGAAAACTCAGAAGGTTAAAGAAGTTCTCAAGAGTCTTGAGCTGATTAGCTGAACATTTTATAT
ACTCCAGCTCAATTTTATTT

Downstream 100 bases:

>100_bases
TTATCAACCAGTACCCCTCATTTTTTTGACCGACTCCTCGTAAGCTTTGGGAACTGGCAGCGGCACTCTCAGGCCAGTTG
AAGGAATTGGATACCTTATC

Product: dihydrodipicolinate reductase (dapB)

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MRVAVSGAAGRMGRLVVKNAVAEGLKVVQAFDINEVGKDAGELAGVGKIGVPIEDDISKLDADVLIDFTTAEAAMKNAEV
AAEKGVRVVMGTTGFTDEDRKRLAELAEKVPMIVSPNFSLGVNIFWKIVEYAAKMLYEWDAEIVELHHRHKRDSPSGTAL
KLAEIIRKVKEEKGIEADLKTCREGISPRESEIGVFGIRGGDVVGEHTVFFFGSGERIELTHRAMSRECFAIGAVRAAKW
IAKVDKPGFYTMDDFLE

Sequences:

>Translated_257_residues
MRVAVSGAAGRMGRLVVKNAVAEGLKVVQAFDINEVGKDAGELAGVGKIGVPIEDDISKLDADVLIDFTTAEAAMKNAEV
AAEKGVRVVMGTTGFTDEDRKRLAELAEKVPMIVSPNFSLGVNIFWKIVEYAAKMLYEWDAEIVELHHRHKRDSPSGTAL
KLAEIIRKVKEEKGIEADLKTCREGISPRESEIGVFGIRGGDVVGEHTVFFFGSGERIELTHRAMSRECFAIGAVRAAKW
IAKVDKPGFYTMDDFLE
>Mature_257_residues
MRVAVSGAAGRMGRLVVKNAVAEGLKVVQAFDINEVGKDAGELAGVGKIGVPIEDDISKLDADVLIDFTTAEAAMKNAEV
AAEKGVRVVMGTTGFTDEDRKRLAELAEKVPMIVSPNFSLGVNIFWKIVEYAAKMLYEWDAEIVELHHRHKRDSPSGTAL
KLAEIIRKVKEEKGIEADLKTCREGISPRESEIGVFGIRGGDVVGEHTVFFFGSGERIELTHRAMSRECFAIGAVRAAKW
IAKVDKPGFYTMDDFLE

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=270, Percent_Identity=41.8518518518518, Blast_Score=186, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_ARCFU (O29353)

Other databases:

- EMBL:   AE000782
- PIR:   E69363
- RefSeq:   NP_069742.1
- ProteinModelPortal:   O29353
- SMR:   O29353
- GeneID:   1484132
- GenomeReviews:   AE000782_GR
- KEGG:   afu:AF0909
- NMPDR:   fig|224325.1.peg.901
- TIGR:   AF_0909
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- ProtClustDB:   CLSK2746656
- BioCyc:   AFUL224325:AF_0909-MONOMER
- BRENDA:   1.3.1.26
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 28097; Mature: 28097

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVAVSGAAGRMGRLVVKNAVAEGLKVVQAFDINEVGKDAGELAGVGKIGVPIEDDISKL
CEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHCCCCCCCCCCHHHHHHC
DADVLIDFTTAEAAMKNAEVAAEKGVRVVMGTTGFTDEDRKRLAELAEKVPMIVSPNFSL
CHHHEEEEEHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCEEECCCCCC
GVNIFWKIVEYAAKMLYEWDAEIVELHHRHKRDSPSGTALKLAEIIRKVKEEKGIEADLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHH
TCREGISPRESEIGVFGIRGGDVVGEHTVFFFGSGERIELTHRAMSRECFAIGAVRAAKW
HHHHCCCCCCCCCEEEEECCCCEECCCEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHH
IAKVDKPGFYTMDDFLE
HHHCCCCCCCCHHHHCC
>Mature Secondary Structure
MRVAVSGAAGRMGRLVVKNAVAEGLKVVQAFDINEVGKDAGELAGVGKIGVPIEDDISKL
CEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHCCCCCCCCCCHHHHHHC
DADVLIDFTTAEAAMKNAEVAAEKGVRVVMGTTGFTDEDRKRLAELAEKVPMIVSPNFSL
CHHHEEEEEHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCEEECCCCCC
GVNIFWKIVEYAAKMLYEWDAEIVELHHRHKRDSPSGTALKLAEIIRKVKEEKGIEADLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHH
TCREGISPRESEIGVFGIRGGDVVGEHTVFFFGSGERIELTHRAMSRECFAIGAVRAAKW
HHHHCCCCCCCCCEEEEECCCCEECCCEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHH
IAKVDKPGFYTMDDFLE
HHHCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475