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Identifier: 11498512

GI number: 11498512

Start: 811172

End: 812431

Strand: Reverse

Name: Not Available

Synonym: AF0907

Alternate gene names: 11498512

Gene position: 812431-811172 (Counterclockwise)

Preceding gene: 11498514

Following gene: 11498511

Centisome position: 37.29

GC content: 51.9

Gene sequence:

>1260_bases
ATGAAAAAAGTTCATATATTTTTGCGCTTACGAACTCAGGTGGGGGCGAGCAGGTACAGATGGGTTGTATTCGGTGTGAT
GGCTTCAATCTACTTCTTTGTTTATTTTCACCGCACGTCATCAGCTATCCTCGCAACCACGCTCATGGAGGAGTTTGCCG
TAACCGCTCTTGCCGTCGGTGTACTCTCATCTGCCTATTTTTACCCCTACGGCTTAATGCAGATTCCGGTGGGTTACCTC
TCCGACACCAAGGGACCGAGGTTGACAACGACCGTGTTCACGCTGCTGGCCTTCGTAGGGACTGTACTCTTCGCCGTGTC
CCCAAACTTTGAAGTGGCCGTTCTTGGGAGATTCCTGATTGGCATCGGCGTGTCGGGAGTTTACATCCCTACGATAAAAC
TGCTATCCCGATGGTTTAGAGTAGACGAGTTTGCCACCTTGACAGGCGTGCTGTTCGCTGTGGGCAATATGGGTGCATTA
GTTTCGGCCTATCCGCTTGCAACGATGGTCTCTCTGTTCGGATGGAGGGTCACGTTTCTCTTCATTGGGGCAATTACCTT
TGTTCTTGCTCTCAGTTGCTGGATTTTCGTGAGGGATTCACCGGGAGGAGTTTTGGAAAAGTCCAGAGAGGGTGGGAGGT
TTGCGACTAATTTTCGCGTGGTGGTGCTCAACCCGGTTGTCTGGTTAATCGCCACGTCTGCCTTTCTGAGATACGGCATC
GTAATGGGCTACCAGGGGCTGTGGGGTGGTCCGTACCTAATGGACGTCTACGGAATGCAGAGGGAAGAGGCTGGCGGTGT
GTTGATGATGGTCGGTCTCGGAACGATTCTGGGAGCGCCAATCATAGGATTCCTCTCAGACAAGGTTTTCAGAACGAGAA
AGTGGTTCCTCGTTGCTGCGGGTATCGGATTCACCTTTACGATGGCTCCGCTCGTCTTCTTCACGGCCAGCCTCACGGTA
TTCCAGCTGTACGCAATATCATTTCTTATTGGCCTTTTCAGCGCTGCGGGTCCGGTTGCCTACGCCCTGATTAAGGAGTC
TTACCCGCTCGAAGTTACCGGTCTGGCGACAAGCATCGTAAACGTTTTCCCCTTCTTTGGCGGAGCCCTCTTCCAGGTTT
TCATGGGCTATCTTATGGACACGGTGGGGATGGTTGATGGCTCCTATCCTCCGGAAGCATACTCACTCGCGTTCTCCTTT
TGCCTCGCTGCATCAGTGGTTTCGGCGGTGCTGATTTTATTTGTCCATGAAAAACGATAA

Upstream 100 bases:

>100_bases
TTATGTACCTCCCAATTTCCTCGGCAAGAGTTTTCGGGTTCATAACAATAATCAGTTTACAATATTTTTACTTTTCGAAA
GTTTGGAAAATTAACACGAT

Downstream 100 bases:

>100_bases
GCTTTTTTAAATCACACGAATTCGTCAAGTTAATGATAATTGGGATTGACGTTGGTGGAACCAACACGGACGCTGCTATT
GTTTCTGACGAAATCAAAAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MKKVHIFLRLRTQVGASRYRWVVFGVMASIYFFVYFHRTSSAILATTLMEEFAVTALAVGVLSSAYFYPYGLMQIPVGYL
SDTKGPRLTTTVFTLLAFVGTVLFAVSPNFEVAVLGRFLIGIGVSGVYIPTIKLLSRWFRVDEFATLTGVLFAVGNMGAL
VSAYPLATMVSLFGWRVTFLFIGAITFVLALSCWIFVRDSPGGVLEKSREGGRFATNFRVVVLNPVVWLIATSAFLRYGI
VMGYQGLWGGPYLMDVYGMQREEAGGVLMMVGLGTILGAPIIGFLSDKVFRTRKWFLVAAGIGFTFTMAPLVFFTASLTV
FQLYAISFLIGLFSAAGPVAYALIKESYPLEVTGLATSIVNVFPFFGGALFQVFMGYLMDTVGMVDGSYPPEAYSLAFSF
CLAASVVSAVLILFVHEKR

Sequences:

>Translated_419_residues
MKKVHIFLRLRTQVGASRYRWVVFGVMASIYFFVYFHRTSSAILATTLMEEFAVTALAVGVLSSAYFYPYGLMQIPVGYL
SDTKGPRLTTTVFTLLAFVGTVLFAVSPNFEVAVLGRFLIGIGVSGVYIPTIKLLSRWFRVDEFATLTGVLFAVGNMGAL
VSAYPLATMVSLFGWRVTFLFIGAITFVLALSCWIFVRDSPGGVLEKSREGGRFATNFRVVVLNPVVWLIATSAFLRYGI
VMGYQGLWGGPYLMDVYGMQREEAGGVLMMVGLGTILGAPIIGFLSDKVFRTRKWFLVAAGIGFTFTMAPLVFFTASLTV
FQLYAISFLIGLFSAAGPVAYALIKESYPLEVTGLATSIVNVFPFFGGALFQVFMGYLMDTVGMVDGSYPPEAYSLAFSF
CLAASVVSAVLILFVHEKR
>Mature_419_residues
MKKVHIFLRLRTQVGASRYRWVVFGVMASIYFFVYFHRTSSAILATTLMEEFAVTALAVGVLSSAYFYPYGLMQIPVGYL
SDTKGPRLTTTVFTLLAFVGTVLFAVSPNFEVAVLGRFLIGIGVSGVYIPTIKLLSRWFRVDEFATLTGVLFAVGNMGAL
VSAYPLATMVSLFGWRVTFLFIGAITFVLALSCWIFVRDSPGGVLEKSREGGRFATNFRVVVLNPVVWLIATSAFLRYGI
VMGYQGLWGGPYLMDVYGMQREEAGGVLMMVGLGTILGAPIIGFLSDKVFRTRKWFLVAAGIGFTFTMAPLVFFTASLTV
FQLYAISFLIGLFSAAGPVAYALIKESYPLEVTGLATSIVNVFPFFGGALFQVFMGYLMDTVGMVDGSYPPEAYSLAFSF
CLAASVVSAVLILFVHEKR

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=371, Percent_Identity=22.6415094339623, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI4503847, Length=371, Percent_Identity=22.6415094339623, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI256219483, Length=371, Percent_Identity=22.6415094339623, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI256219543, Length=392, Percent_Identity=22.7040816326531, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI2367379, Length=416, Percent_Identity=23.5576923076923, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI87082310, Length=404, Percent_Identity=23.2673267326733, Blast_Score=71, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281364404, Length=304, Percent_Identity=23.6842105263158, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28574037, Length=304, Percent_Identity=23.6842105263158, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21356765, Length=301, Percent_Identity=23.2558139534884, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45852; Mature: 45852

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS50850 MFS ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVHIFLRLRTQVGASRYRWVVFGVMASIYFFVYFHRTSSAILATTLMEEFAVTALAVG
CCEEEEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VLSSAYFYPYGLMQIPVGYLSDTKGPRLTTTVFTLLAFVGTVLFAVSPNFEVAVLGRFLI
HHHHHHHCCCCHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
GIGVSGVYIPTIKLLSRWFRVDEFATLTGVLFAVGNMGALVSAYPLATMVSLFGWRVTFL
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
FIGAITFVLALSCWIFVRDSPGGVLEKSREGGRFATNFRVVVLNPVVWLIATSAFLRYGI
HHHHHHHHHHHHHEEEEECCCCCHHHCCCCCCCEEEEEEEEEEHHHHHHHHHHHHHHHHH
VMGYQGLWGGPYLMDVYGMQREEAGGVLMMVGLGTILGAPIIGFLSDKVFRTRKWFLVAA
HHCCCCCCCCCHHHHHHCCCHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHEEEEEEE
GIGFTFTMAPLVFFTASLTVFQLYAISFLIGLFSAAGPVAYALIKESYPLEVTGLATSIV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEHHHHHHHH
NVFPFFGGALFQVFMGYLMDTVGMVDGSYPPEAYSLAFSFCLAASVVSAVLILFVHEKR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKVHIFLRLRTQVGASRYRWVVFGVMASIYFFVYFHRTSSAILATTLMEEFAVTALAVG
CCEEEEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VLSSAYFYPYGLMQIPVGYLSDTKGPRLTTTVFTLLAFVGTVLFAVSPNFEVAVLGRFLI
HHHHHHHCCCCHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
GIGVSGVYIPTIKLLSRWFRVDEFATLTGVLFAVGNMGALVSAYPLATMVSLFGWRVTFL
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
FIGAITFVLALSCWIFVRDSPGGVLEKSREGGRFATNFRVVVLNPVVWLIATSAFLRYGI
HHHHHHHHHHHHHEEEEECCCCCHHHCCCCCCCEEEEEEEEEEHHHHHHHHHHHHHHHHH
VMGYQGLWGGPYLMDVYGMQREEAGGVLMMVGLGTILGAPIIGFLSDKVFRTRKWFLVAA
HHCCCCCCCCCHHHHHHCCCHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHEEEEEEE
GIGFTFTMAPLVFFTASLTVFQLYAISFLIGLFSAAGPVAYALIKESYPLEVTGLATSIV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEHHHHHHHH
NVFPFFGGALFQVFMGYLMDTVGMVDGSYPPEAYSLAFSFCLAASVVSAVLILFVHEKR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]