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The map label for this gene is fadD-3

Identifier: 11498295

GI number: 11498295

Start: 618140

End: 619789

Strand: Reverse

Name: fadD-3

Synonym: AF0687

Alternate gene names: 11498295

Gene position: 619789-618140 (Counterclockwise)

Preceding gene: 11498298

Following gene: 11498288

Centisome position: 28.45

GC content: 48.18

Gene sequence:

>1650_bases
ATGAGAGGAGAGGATGTATTTTACGAAATTAATGACGAAAACGTCAGAGAGCTGAGAAAGAGATACAACAAAATCAGAAG
GTGGGTAATTGCGGACTTTTTGAGGCGGAGCGGGAGAAGATATCCGGAAAAAACTGCGCTTATCTTCAACCATCCCGATG
GCAGGGAGATCAGACTAACTTACAGCGAGCTGGACAAAATGGCAAATAAGGTGGCAAATGCTCTCCTGAATTTGGGGATA
AAGAAGTATGACAGAGTTGCCATTCTCGCTCACAACACCCTGCACCACGTTTTGACAATCTTCGGCTGTGCTAAGGCTGG
AGCGATATATCTCGGCCTGAACTACCTGATGTACGGAAAAGATCTGGCCTACTGCATCAACCACTCGGAGGCAAAGGTTC
TGATTGTTGAGGATGCTCTGTTTGAAAGAATCGAGCCGGCGATGGACCAGCTCAAGACGGTCGATACGTTCCTGTGGTCG
AATCAGGGTGTTGGGGTTGAAGGTGAAGGGAGATGGGAAAGTTTCGATGATTTCTTTGATGGAGAGAGTGATACGGAGCC
AGATACGATACTGAACATCGAAGACCCGGTGCAGATGACCTACACAAGCGGAACTGAGAGTCTGCCGAAGTGTGTTGTTC
ACACCAATGAGTCGCTTATAGCCCAATATGTTGGATGCATAGTGGATGGGGAGTACACAGCTAATGACATCATGCTTAAC
ACGATGCCCATCTACCACTGCGCCCAGCGAGATGTCTTCATGATGCCAATATTCTACGTTGGCGGAACGAATGTAATGAT
GACGGAGCCCAATCTGGATTTAATGCTGGAATACATTGACAGATACAAGCCCACGATGCTCTTCCTTGCCCCCACTGTCT
GGATAGGATTGCTGAGACATCCTGATATCGACAAATATGACCTTCAATCACTGAGAAAGTGCTACTACGGGGCCTCAATC
TTTCCGGAGGAGCCCCTGAAAGAGCTCATGGAGAAGCTTCCACAGGCGAGATTTTTCCAGTACTACGGACAGACGGAGCT
CGCTCCATACCACACAGTTGCGAACCATGAAGAGATACTGGAGTACACAAAGACTGCTGGCAGAAGCGGGCTGAATCTTG
AGTCAAGGCTTGAAAACGACGAGCATGAGGAGATAGCTGAAATAGGGGTTCCGGGAGAGATTACCGCCCGCGGACCTCAC
GTTATGCTGATGTACTACAAAGACCCGGAGAAGACTGAAGAGGCTTTCAAATGCGGATGGTTCCACAGCGGTGACATTGC
GGTGAAGTACAGGGAAAGCTACTTCGAAATCGTTGACAGAAAGAAGGACATGATAAAGACTGGTGGTGAGAACGTATCCA
GCAGGGAGGTGGAGGAGGTTATATACAAGCACCCTGACGTCTGGGAGGTTGCCGTCATCGGTTTGCCGCATGAAAAATGG
ATTGAGGCTGTAACGGCAATCGTTGTGCCCAAGCCGGGGAAAACAATCAATCCTGAGGAGATTATTGAGTTCTGCCGTAA
GGAACTCTCCCCCTACAAGGTTCCCAAAGGTGTAATCGTGCTTAAGCCTGAAGATTTGCCAAAAACGCCGTCTGGAAAGA
TAATGAAAAGGGAGTTGAGGAAAATCTTTAAGGATTATTATTCGGCTTGA

Upstream 100 bases:

>100_bases
AAATTGATGTTTTGCAAGACAGCATGACAGCTTGGTTCTCACATGGATTGTACGAATCAATATAGTAAATTTTTTTAAAA
TTAAAAATTGACACCAATAC

Downstream 100 bases:

>100_bases
AGGAAGAGCTAAGAGAGTACTGCTCAAAATACATCGCCGACTACAAAATGTTTTTCCCATTTAGGGCCTTCCTGTTCAGC
AATTCGGTGTATTTTTCCCA

Product: acyl-CoA synthetase

Products: AMP; diphosphate; acyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MRGEDVFYEINDENVRELRKRYNKIRRWVIADFLRRSGRRYPEKTALIFNHPDGREIRLTYSELDKMANKVANALLNLGI
KKYDRVAILAHNTLHHVLTIFGCAKAGAIYLGLNYLMYGKDLAYCINHSEAKVLIVEDALFERIEPAMDQLKTVDTFLWS
NQGVGVEGEGRWESFDDFFDGESDTEPDTILNIEDPVQMTYTSGTESLPKCVVHTNESLIAQYVGCIVDGEYTANDIMLN
TMPIYHCAQRDVFMMPIFYVGGTNVMMTEPNLDLMLEYIDRYKPTMLFLAPTVWIGLLRHPDIDKYDLQSLRKCYYGASI
FPEEPLKELMEKLPQARFFQYYGQTELAPYHTVANHEEILEYTKTAGRSGLNLESRLENDEHEEIAEIGVPGEITARGPH
VMLMYYKDPEKTEEAFKCGWFHSGDIAVKYRESYFEIVDRKKDMIKTGGENVSSREVEEVIYKHPDVWEVAVIGLPHEKW
IEAVTAIVVPKPGKTINPEEIIEFCRKELSPYKVPKGVIVLKPEDLPKTPSGKIMKRELRKIFKDYYSA

Sequences:

>Translated_549_residues
MRGEDVFYEINDENVRELRKRYNKIRRWVIADFLRRSGRRYPEKTALIFNHPDGREIRLTYSELDKMANKVANALLNLGI
KKYDRVAILAHNTLHHVLTIFGCAKAGAIYLGLNYLMYGKDLAYCINHSEAKVLIVEDALFERIEPAMDQLKTVDTFLWS
NQGVGVEGEGRWESFDDFFDGESDTEPDTILNIEDPVQMTYTSGTESLPKCVVHTNESLIAQYVGCIVDGEYTANDIMLN
TMPIYHCAQRDVFMMPIFYVGGTNVMMTEPNLDLMLEYIDRYKPTMLFLAPTVWIGLLRHPDIDKYDLQSLRKCYYGASI
FPEEPLKELMEKLPQARFFQYYGQTELAPYHTVANHEEILEYTKTAGRSGLNLESRLENDEHEEIAEIGVPGEITARGPH
VMLMYYKDPEKTEEAFKCGWFHSGDIAVKYRESYFEIVDRKKDMIKTGGENVSSREVEEVIYKHPDVWEVAVIGLPHEKW
IEAVTAIVVPKPGKTINPEEIIEFCRKELSPYKVPKGVIVLKPEDLPKTPSGKIMKRELRKIFKDYYSA
>Mature_549_residues
MRGEDVFYEINDENVRELRKRYNKIRRWVIADFLRRSGRRYPEKTALIFNHPDGREIRLTYSELDKMANKVANALLNLGI
KKYDRVAILAHNTLHHVLTIFGCAKAGAIYLGLNYLMYGKDLAYCINHSEAKVLIVEDALFERIEPAMDQLKTVDTFLWS
NQGVGVEGEGRWESFDDFFDGESDTEPDTILNIEDPVQMTYTSGTESLPKCVVHTNESLIAQYVGCIVDGEYTANDIMLN
TMPIYHCAQRDVFMMPIFYVGGTNVMMTEPNLDLMLEYIDRYKPTMLFLAPTVWIGLLRHPDIDKYDLQSLRKCYYGASI
FPEEPLKELMEKLPQARFFQYYGQTELAPYHTVANHEEILEYTKTAGRSGLNLESRLENDEHEEIAEIGVPGEITARGPH
VMLMYYKDPEKTEEAFKCGWFHSGDIAVKYRESYFEIVDRKKDMIKTGGENVSSREVEEVIYKHPDVWEVAVIGLPHEKW
IEAVTAIVVPKPGKTINPEEIIEFCRKELSPYKVPKGVIVLKPEDLPKTPSGKIMKRELRKIFKDYYSA

Specific function: Esterification, Concomitant With Transport, Of Exogenous Long-Chain Fatty Acids Into Metabolically Active CoA Thioesters For Subsequent Degradation Or Incorporation Into Phospholipids. [C]

COG id: COG0318

COG function: function code IQ; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II

Gene ontology:

Cell location: Partially Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI156151445, Length=548, Percent_Identity=29.014598540146, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI122937307, Length=566, Percent_Identity=28.4452296819788, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI38505220, Length=527, Percent_Identity=26.3757115749526, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI187761345, Length=547, Percent_Identity=25.4113345521024, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI187761343, Length=547, Percent_Identity=25.4113345521024, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI42544132, Length=524, Percent_Identity=25.763358778626, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI28416953, Length=563, Percent_Identity=26.8206039076377, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI157311624, Length=525, Percent_Identity=24.952380952381, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI157311622, Length=525, Percent_Identity=24.952380952381, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI58082049, Length=525, Percent_Identity=25.1428571428571, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI115511026, Length=531, Percent_Identity=23.1638418079096, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI227499619, Length=514, Percent_Identity=24.9027237354086, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI40807491, Length=498, Percent_Identity=23.4939759036145, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI42544134, Length=322, Percent_Identity=25.1552795031056, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI8923896, Length=153, Percent_Identity=33.9869281045752, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI253970489, Length=153, Percent_Identity=33.9869281045752, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI227499621, Length=212, Percent_Identity=30.6603773584906, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI83745141, Length=282, Percent_Identity=23.0496453900709, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1788107, Length=544, Percent_Identity=29.2279411764706, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI145693145, Length=532, Percent_Identity=28.0075187969925, Blast_Score=198, Evalue=8e-52,
Organism=Escherichia coli, GI221142682, Length=521, Percent_Identity=27.831094049904, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1790505, Length=555, Percent_Identity=27.5675675675676, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI1786810, Length=549, Percent_Identity=23.6794171220401, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1786529, Length=567, Percent_Identity=23.6331569664903, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1789201, Length=353, Percent_Identity=24.3626062322946, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71994694, Length=557, Percent_Identity=29.9820466786355, Blast_Score=194, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI71994703, Length=557, Percent_Identity=29.9820466786355, Blast_Score=194, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI71994690, Length=557, Percent_Identity=29.9820466786355, Blast_Score=194, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17560308, Length=559, Percent_Identity=28.9803220035778, Blast_Score=186, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17559526, Length=513, Percent_Identity=28.0701754385965, Blast_Score=176, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17558820, Length=512, Percent_Identity=27.9296875, Blast_Score=152, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI32563687, Length=496, Percent_Identity=26.8145161290323, Blast_Score=151, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17531443, Length=510, Percent_Identity=26.6666666666667, Blast_Score=145, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI71996755, Length=488, Percent_Identity=26.2295081967213, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17557194, Length=523, Percent_Identity=23.9005736137667, Blast_Score=129, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17538037, Length=523, Percent_Identity=24.6653919694073, Blast_Score=128, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17560140, Length=521, Percent_Identity=24.5681381957774, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI25147511, Length=586, Percent_Identity=23.7201365187713, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71985884, Length=381, Percent_Identity=22.5721784776903, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17551278, Length=550, Percent_Identity=25.8181818181818, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI115534440, Length=549, Percent_Identity=22.040072859745, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71982997, Length=563, Percent_Identity=23.0905861456483, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71983001, Length=563, Percent_Identity=23.0905861456483, Blast_Score=79, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17556552, Length=103, Percent_Identity=40.7766990291262, Blast_Score=69, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6319264, Length=554, Percent_Identity=26.3537906137184, Blast_Score=120, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6323182, Length=584, Percent_Identity=26.7123287671233, Blast_Score=116, Evalue=9e-27,
Organism=Saccharomyces cerevisiae, GI6319699, Length=517, Percent_Identity=22.8239845261122, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI21355181, Length=517, Percent_Identity=26.6924564796905, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24581924, Length=550, Percent_Identity=26.3636363636364, Blast_Score=159, Evalue=5e-39,
Organism=Drosophila melanogaster, GI18859661, Length=498, Percent_Identity=25.1004016064257, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI24648260, Length=508, Percent_Identity=26.9685039370079, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24667955, Length=538, Percent_Identity=26.5799256505576, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI62472339, Length=538, Percent_Identity=26.5799256505576, Blast_Score=125, Evalue=7e-29,
Organism=Drosophila melanogaster, GI21356441, Length=534, Percent_Identity=24.7191011235955, Blast_Score=121, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24648255, Length=512, Percent_Identity=25.1953125, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24648253, Length=522, Percent_Identity=24.904214559387, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21356947, Length=523, Percent_Identity=23.7093690248566, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI19922652, Length=496, Percent_Identity=24.5967741935484, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28573631, Length=563, Percent_Identity=24.5115452930728, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI20130353, Length=563, Percent_Identity=24.5115452930728, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI281365686, Length=465, Percent_Identity=23.8709677419355, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24653035, Length=524, Percent_Identity=23.0916030534351, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI20130357, Length=494, Percent_Identity=21.6599190283401, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24583465, Length=560, Percent_Identity=24.2857142857143, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24583463, Length=560, Percent_Identity=24.2857142857143, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI281364798, Length=560, Percent_Identity=24.2857142857143, Blast_Score=102, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24648257, Length=529, Percent_Identity=23.062381852552, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21358303, Length=476, Percent_Identity=23.3193277310924, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24667959, Length=490, Percent_Identity=25.3061224489796, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21355225, Length=583, Percent_Identity=23.8421955403087, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI161076582, Length=514, Percent_Identity=22.7626459143969, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: 6.2.1.3

Molecular weight: Translated: 63347; Mature: 63347

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGEDVFYEINDENVRELRKRYNKIRRWVIADFLRRSGRRYPEKTALIFNHPDGREIRLT
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEE
YSELDKMANKVANALLNLGIKKYDRVAILAHNTLHHVLTIFGCAKAGAIYLGLNYLMYGK
HHHHHHHHHHHHHHHHHCCCHHCCCEEEEEHHHHHHHHHHHHHHHCCEEEEEHHHHHHCC
DLAYCINHSEAKVLIVEDALFERIEPAMDQLKTVDTFLWSNQGVGVEGEGRWESFDDFFD
HHHEEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCC
GESDTEPDTILNIEDPVQMTYTSGTESLPKCVVHTNESLIAQYVGCIVDGEYTANDIMLN
CCCCCCCCEEEECCCCCEEEECCCCCHHCHHHEECCHHHHHHHHHHEECCCCCCCCEEEE
TMPIYHCAQRDVFMMPIFYVGGTNVMMTEPNLDLMLEYIDRYKPTMLFLAPTVWIGLLRH
CCCHHHHCCCCEEEEEEEEECCCEEEEECCCHHHHHHHHHHCCCEEEEEHHHHHHHHHCC
PDIDKYDLQSLRKCYYGASIFPEEPLKELMEKLPQARFFQYYGQTELAPYHTVANHEEIL
CCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHCCCCCCCCCHHHCCHHHHH
EYTKTAGRSGLNLESRLENDEHEEIAEIGVPGEITARGPHVMLMYYKDPEKTEEAFKCGW
HHHHHCCCCCCCHHHHCCCCHHHHHHHCCCCCCEECCCCEEEEEEECCCCHHHHHHHCCC
FHSGDIAVKYRESYFEIVDRKKDMIKTGGENVSSREVEEVIYKHPDVWEVAVIGLPHEKW
EECCCEEEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEEEECCHHHH
IEAVTAIVVPKPGKTINPEEIIEFCRKELSPYKVPKGVIVLKPEDLPKTPSGKIMKRELR
HHHHHEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHH
KIFKDYYSA
HHHHHHHCC
>Mature Secondary Structure
MRGEDVFYEINDENVRELRKRYNKIRRWVIADFLRRSGRRYPEKTALIFNHPDGREIRLT
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEE
YSELDKMANKVANALLNLGIKKYDRVAILAHNTLHHVLTIFGCAKAGAIYLGLNYLMYGK
HHHHHHHHHHHHHHHHHCCCHHCCCEEEEEHHHHHHHHHHHHHHHCCEEEEEHHHHHHCC
DLAYCINHSEAKVLIVEDALFERIEPAMDQLKTVDTFLWSNQGVGVEGEGRWESFDDFFD
HHHEEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCC
GESDTEPDTILNIEDPVQMTYTSGTESLPKCVVHTNESLIAQYVGCIVDGEYTANDIMLN
CCCCCCCCEEEECCCCCEEEECCCCCHHCHHHEECCHHHHHHHHHHEECCCCCCCCEEEE
TMPIYHCAQRDVFMMPIFYVGGTNVMMTEPNLDLMLEYIDRYKPTMLFLAPTVWIGLLRH
CCCHHHHCCCCEEEEEEEEECCCEEEEECCCHHHHHHHHHHCCCEEEEEHHHHHHHHHCC
PDIDKYDLQSLRKCYYGASIFPEEPLKELMEKLPQARFFQYYGQTELAPYHTVANHEEIL
CCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHCCCCCCCCCHHHCCHHHHH
EYTKTAGRSGLNLESRLENDEHEEIAEIGVPGEITARGPHVMLMYYKDPEKTEEAFKCGW
HHHHHCCCCCCCHHHHCCCCHHHHHHHCCCCCCEECCCCEEEEEEECCCCHHHHHHHCCC
FHSGDIAVKYRESYFEIVDRKKDMIKTGGENVSSREVEEVIYKHPDVWEVAVIGLPHEKW
EECCCEEEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEEEECCHHHH
IEAVTAIVVPKPGKTINPEEIIEFCRKELSPYKVPKGVIVLKPEDLPKTPSGKIMKRELR
HHHHHEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHH
KIFKDYYSA
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Salts [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.0408 {octanoate}} 0.0125 {octanoate}} 0.0059 {octanoate}} 0.00072 {octanoate}} 0.0013 {undecanoate}} 0.0022 {pentadecanoate}} 0.053 {CoA}} 0.035 {CoA}} 0.034 {CoA}} 0.0034 {tridecanoate}} 0.002 {laurate}} 0.0019 {laurate}} 0.0

Substrates: ATP; long-chain carboxylic acid; CoA

Specific reaction: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA

General reaction: Acid-thiol ligation; Phosphorylation [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]