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Identifier: 11498117

GI number: 11498117

Start: 464235

End: 465335

Strand: Reverse

Name: Not Available

Synonym: AF0506

Alternate gene names: 11498117

Gene position: 465335-464235 (Counterclockwise)

Preceding gene: 11498118

Following gene: 11498115

Centisome position: 21.36

GC content: 48.5

Gene sequence:

>1101_bases
ATGAACATCAGAGAGATTGCAGCGAAGTGCAGCAAGTGCGGATACTGCACAACCTGCCCAACCTACAGGATAGAGGGATG
GGAAACCGTATCTCCGAGGGGGAAGATTCAGCTAGCCCTAAAATATGTGGATGGGGAGATAGACGTTGACCAGAAAATCG
TCAAGGACATTTTCAAGTGCTCGGTGTGCGGCTTGTGTCAGGAAGTCTGCCCGGTAGAGCTTCCCCTAATCGACTTCTGG
GAGGAACTGAGAAGGACGCTCGTTCAAAAGGGACTGGCTCCGCTCTCTGTTCACAGAAAGCTCAGGGAGATTACCTTCAG
AAACTACAACCCCTACAGTGGTGATCAGGAAAGGAGGGGGGACTGGGCAGACTTTGAGATAAAACCTGCTAAGACGCTGT
ATTTTGCGGGCTGCACCGCAAGCTTCAGATTGCAAAATCTTGCCAAGTCAACAGCCAGCGTTCTGGAAAAGCTCGGAATC
GATTTTACAATTGCCGGTAAGAATGAGTACTGCTGCGGTTCCCCGTTCCTGCGAACAGGACAGAAAGACATTGTTGAAAG
GCTGTTTGAGAAAAACTACGCATACTGGCAGAAGATGGGAATAGAGAGGATAATAACGTCCTGTCCCGGATGCTACAGAA
CGATATCACTGGACTACCCCAAAATTGCGGAGGAGAAAGGCTACGAGTTTGACATTGAGGTTGTCCACACCGTCTCAATA
CTCGATAAAATGGGGGAGTTTGAAAAAATAGATTTGAAGGCAACTTATCATGACCCCTGTCACCTAGGAAGGCATATGGG
GATGTACGAGGAGCCGAGAAACGTTATAAAGAGGCTTGGCATCAACTTTGTGGAGATGGAGAGAAACAGAGAGCAGGCTC
TTTGCTGCGGCGCTGGTGGGGGATTGAGGAGTCAGTTCCCTGAAATTTCCTTTGAAATCGGAAGGCAGAGAGTTCTGGAA
GCGATGGAAACGGGGGCGGAATACCTCATTACCTGCTGTCCCTTCTGCGAGTATCACCTATCTAAATCTGCAGAAAAGCT
TGGCAATAGAATCAAAGTCGTTGATTTAGTCGAAATCGCAGAAAAGCTAATCTCTCCCTGA

Upstream 100 bases:

>100_bases
ATTTCAAAAAGGCCGTTGACCCTGAATCACTGCTCAATCCGGGAAAGGCTGTTGAGAGTAACAGCTTTTCCAGGCTGATA
AGGCTCGTGGAGATGGTGCT

Downstream 100 bases:

>100_bases
TTGAAACTCTTCTGCCGTCAAACCGAGCGTGAAAGAGCGCGTTCAGAAGGTCAAACTCGTCGGGTAAGTAGTTAATAGCC
AAGCCAACCGCTCTGGCTGA

Product: iron-sulfur binding reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MNIREIAAKCSKCGYCTTCPTYRIEGWETVSPRGKIQLALKYVDGEIDVDQKIVKDIFKCSVCGLCQEVCPVELPLIDFW
EELRRTLVQKGLAPLSVHRKLREITFRNYNPYSGDQERRGDWADFEIKPAKTLYFAGCTASFRLQNLAKSTASVLEKLGI
DFTIAGKNEYCCGSPFLRTGQKDIVERLFEKNYAYWQKMGIERIITSCPGCYRTISLDYPKIAEEKGYEFDIEVVHTVSI
LDKMGEFEKIDLKATYHDPCHLGRHMGMYEEPRNVIKRLGINFVEMERNREQALCCGAGGGLRSQFPEISFEIGRQRVLE
AMETGAEYLITCCPFCEYHLSKSAEKLGNRIKVVDLVEIAEKLISP

Sequences:

>Translated_366_residues
MNIREIAAKCSKCGYCTTCPTYRIEGWETVSPRGKIQLALKYVDGEIDVDQKIVKDIFKCSVCGLCQEVCPVELPLIDFW
EELRRTLVQKGLAPLSVHRKLREITFRNYNPYSGDQERRGDWADFEIKPAKTLYFAGCTASFRLQNLAKSTASVLEKLGI
DFTIAGKNEYCCGSPFLRTGQKDIVERLFEKNYAYWQKMGIERIITSCPGCYRTISLDYPKIAEEKGYEFDIEVVHTVSI
LDKMGEFEKIDLKATYHDPCHLGRHMGMYEEPRNVIKRLGINFVEMERNREQALCCGAGGGLRSQFPEISFEIGRQRVLE
AMETGAEYLITCCPFCEYHLSKSAEKLGNRIKVVDLVEIAEKLISP
>Mature_366_residues
MNIREIAAKCSKCGYCTTCPTYRIEGWETVSPRGKIQLALKYVDGEIDVDQKIVKDIFKCSVCGLCQEVCPVELPLIDFW
EELRRTLVQKGLAPLSVHRKLREITFRNYNPYSGDQERRGDWADFEIKPAKTLYFAGCTASFRLQNLAKSTASVLEKLGI
DFTIAGKNEYCCGSPFLRTGQKDIVERLFEKNYAYWQKMGIERIITSCPGCYRTISLDYPKIAEEKGYEFDIEVVHTVSI
LDKMGEFEKIDLKATYHDPCHLGRHMGMYEEPRNVIKRLGINFVEMERNREQALCCGAGGGLRSQFPEISFEIGRQRVLE
AMETGAEYLITCCPFCEYHLSKSAEKLGNRIKVVDLVEIAEKLISP

Specific function: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit [H]

COG id: COG0247

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI48994913, Length=395, Percent_Identity=25.0632911392405, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786497, Length=236, Percent_Identity=27.1186440677966, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788576, Length=393, Percent_Identity=23.9185750636132, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR004017
- InterPro:   IPR012285
- InterPro:   IPR009051 [H]

Pfam domain/function: PF02754 CCG [H]

EC number: =1.8.98.1 [H]

Molecular weight: Translated: 41809; Mature: 41809

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
5.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIREIAAKCSKCGYCTTCPTYRIEGWETVSPRGKIQLALKYVDGEIDVDQKIVKDIFKC
CCHHHHHHHHHCCCCCCCCCCEEECCCEECCCCCCEEEEEEEECCCCCHHHHHHHHHHHH
SVCGLCQEVCPVELPLIDFWEELRRTLVQKGLAPLSVHRKLREITFRNYNPYSGDQERRG
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHCC
DWADFEIKPAKTLYFAGCTASFRLQNLAKSTASVLEKLGIDFTIAGKNEYCCGSPFLRTG
CCCCEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHCC
QKDIVERLFEKNYAYWQKMGIERIITSCPGCYRTISLDYPKIAEEKGYEFDIEVVHTVSI
HHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHCCCEEEHHHHHHHHH
LDKMGEFEKIDLKATYHDPCHLGRHMGMYEEPRNVIKRLGINFVEMERNREQALCCGAGG
HHHCCCCEEEEEEEECCCHHHHHHHCCCHHHHHHHHHHHCCCCEEECCCCCCEEEECCCC
GLRSQFPEISFEIGRQRVLEAMETGAEYLITCCPFCEYHLSKSAEKLGNRIKVVDLVEIA
CHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHH
EKLISP
HHHCCC
>Mature Secondary Structure
MNIREIAAKCSKCGYCTTCPTYRIEGWETVSPRGKIQLALKYVDGEIDVDQKIVKDIFKC
CCHHHHHHHHHCCCCCCCCCCEEECCCEECCCCCCEEEEEEEECCCCCHHHHHHHHHHHH
SVCGLCQEVCPVELPLIDFWEELRRTLVQKGLAPLSVHRKLREITFRNYNPYSGDQERRG
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHCC
DWADFEIKPAKTLYFAGCTASFRLQNLAKSTASVLEKLGIDFTIAGKNEYCCGSPFLRTG
CCCCEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHCC
QKDIVERLFEKNYAYWQKMGIERIITSCPGCYRTISLDYPKIAEEKGYEFDIEVVHTVSI
HHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHCCCEEEHHHHHHHHH
LDKMGEFEKIDLKATYHDPCHLGRHMGMYEEPRNVIKRLGINFVEMERNREQALCCGAGG
HHHCCCCEEEEEEEECCCHHHHHHHCCCHHHHHHHHHHHCCCCEEECCCCCCEEEECCCC
GLRSQFPEISFEIGRQRVLEAMETGAEYLITCCPFCEYHLSKSAEKLGNRIKVVDLVEIA
CHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHH
EKLISP
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9063468; 8174566 [H]