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Identifier: 15679884

GI number: 15679884

Start: 1734464

End: 1735156

Strand: Direct

Name: Not Available

Synonym: MTH1902

Alternate gene names: NA

Gene position: 1734464-1735156 (Clockwise)

Preceding gene: 15679883

Following gene: 15679885

Centisome position: 99.03

GC content: 47.33

Gene sequence:

>693_bases
ATGAGAATTCAGTGGTTTGGACATTCAGCATTTGAGATAACATCCTCTGATACAAGGATACTTCTGGATCCCTTCATAAG
TAACAACCCTGTCTGCAGCACAGCAGTTGAGGAGTTCGAACCAGACGTGATATGCGTCACCCATGGACACGCAGACCATC
TCGGCGATGCAATGGAGATCGCTGAGAGGACAGGCGCACTCCTGATAGCGAACCATGAACTATCTGTTTTTTTCTCAAGG
CAGGGCCTTGAAAGTACCGGGATGAACATCGGTGGAAAAATTTCCATTGATGGTATAGGGATAAGGATGGTTGATGCAAA
GCATTCATCAGATATAGACTTTACAGAGGAGGTGACATCTGGAGGCAGTGCCTGTGGCTTTATAATTGAGACCCGTGAGG
GTAAGGTGTATCATGCCGGTGATACCGGTCTTTTTGCAGATATGAGGGATGTTATAGGTGAGATTTACAGGCCTGATATT
GCACTCTTACCGATAGGCGACAGATACACCATGGGGCCTGAGGATGCAGCAGTGGCAGCCGGCTGGATAAAACCTGAAAA
GGTTCTCCCGATGCACTACAATACGTTTCCCGTCATTGAACAGAACCCCGAAATATTTGCTGAACTTGTTGAAAGGACAT
CCCCCGGTACAGAGGTCGTCATCCTCGATGTCGGAGGATTCTATGAATACTGA

Upstream 100 bases:

>100_bases
TTGGTGTCATCTACAAGGATAAAAAATCGATCTCTGAGATCAAAAAACTCTTTGAGGAGGCATGGGAACTTTCCAATGAA
ATCAATCTGGAGGGAGTTTA

Downstream 100 bases:

>100_bases
TTAATCAAGGAAAGAGTGATAGGATGGCAAATTTTTTCACAAACTTCCTGGATAAACTGCTTGGAAGGAACAAGAAACTT
AAGATTGGACTCTATGGTCA

Product: metal-dependent hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MRIQWFGHSAFEITSSDTRILLDPFISNNPVCSTAVEEFEPDVICVTHGHADHLGDAMEIAERTGALLIANHELSVFFSR
QGLESTGMNIGGKISIDGIGIRMVDAKHSSDIDFTEEVTSGGSACGFIIETREGKVYHAGDTGLFADMRDVIGEIYRPDI
ALLPIGDRYTMGPEDAAVAAGWIKPEKVLPMHYNTFPVIEQNPEIFAELVERTSPGTEVVILDVGGFYEY

Sequences:

>Translated_230_residues
MRIQWFGHSAFEITSSDTRILLDPFISNNPVCSTAVEEFEPDVICVTHGHADHLGDAMEIAERTGALLIANHELSVFFSR
QGLESTGMNIGGKISIDGIGIRMVDAKHSSDIDFTEEVTSGGSACGFIIETREGKVYHAGDTGLFADMRDVIGEIYRPDI
ALLPIGDRYTMGPEDAAVAAGWIKPEKVLPMHYNTFPVIEQNPEIFAELVERTSPGTEVVILDVGGFYEY
>Mature_230_residues
MRIQWFGHSAFEITSSDTRILLDPFISNNPVCSTAVEEFEPDVICVTHGHADHLGDAMEIAERTGALLIANHELSVFFSR
QGLESTGMNIGGKISIDGIGIRMVDAKHSSDIDFTEEVTSGGSACGFIIETREGKVYHAGDTGLFADMRDVIGEIYRPDI
ALLPIGDRYTMGPEDAAVAAGWIKPEKVLPMHYNTFPVIEQNPEIFAELVERTSPGTEVVILDVGGFYEY

Specific function: Unknown

COG id: COG2220

COG function: function code R; Predicted Zn-dependent hydrolases of the beta-lactamase fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0173 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1902_METTH (O27924)

Other databases:

- EMBL:   AE000666
- PIR:   A69121
- RefSeq:   NP_277002.1
- ProteinModelPortal:   O27924
- STRING:   O27924
- GeneID:   1470987
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH1902
- NMPDR:   fig|187420.1.peg.1857
- eggNOG:   arNOG08649
- HOGENOM:   HBG741314
- OMA:   VILLTHG
- ProtClustDB:   PRK00685
- BioCyc:   MTHE187420:MTH1902-MONOMER
- HAMAP:   MF_00457
- InterPro:   IPR001279
- InterPro:   IPR022877
- SMART:   SM00849

Pfam domain/function: PF00753 Lactamase_B

EC number: NA

Molecular weight: Translated: 25169; Mature: 25169

Theoretical pI: Translated: 4.24; Mature: 4.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIQWFGHSAFEITSSDTRILLDPFISNNPVCSTAVEEFEPDVICVTHGHADHLGDAMEI
CEEEEECCCEEEEECCCCEEEEECCCCCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHH
AERTGALLIANHELSVFFSRQGLESTGMNIGGKISIDGIGIRMVDAKHSSDIDFTEEVTS
HHHCCEEEEECCCEEEEEECCCCCCCCCCCCCEEEECCEEEEEEECCCCCCCCHHHHHHC
GGSACGFIIETREGKVYHAGDTGLFADMRDVIGEIYRPDIALLPIGDRYTMGPEDAAVAA
CCCEEEEEEECCCCEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHEEE
GWIKPEKVLPMHYNTFPVIEQNPEIFAELVERTSPGTEVVILDVGGFYEY
CCCCCCEEEEEECCCCCEEECCHHHHHHHHHHCCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MRIQWFGHSAFEITSSDTRILLDPFISNNPVCSTAVEEFEPDVICVTHGHADHLGDAMEI
CEEEEECCCEEEEECCCCEEEEECCCCCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHH
AERTGALLIANHELSVFFSRQGLESTGMNIGGKISIDGIGIRMVDAKHSSDIDFTEEVTS
HHHCCEEEEECCCEEEEEECCCCCCCCCCCCCEEEECCEEEEEEECCCCCCCCHHHHHHC
GGSACGFIIETREGKVYHAGDTGLFADMRDVIGEIYRPDIALLPIGDRYTMGPEDAAVAA
CCCEEEEEEECCCCEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHEEE
GWIKPEKVLPMHYNTFPVIEQNPEIFAELVERTSPGTEVVILDVGGFYEY
CCCCCCEEEEEECCCCCEEECCHHHHHHHHHHCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463