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Identifier: 15679871

GI number: 15679871

Start: 1715556

End: 1716476

Strand: Direct

Name: Not Available

Synonym: MTH1883

Alternate gene names: 15679871

Gene position: 1715556-1716476 (Clockwise)

Preceding gene: 15679870

Following gene: 15679872

Centisome position: 97.95

GC content: 46.58

Gene sequence:

>921_bases
ATGATAATGGTTCAGGGAGAGGTAAGTGGAAAGAAATACACAGAGCCATTCTCCAAGGGTGTTCTGGCACGTTCACTGAC
CCGGGCAGAGATGGATCCAAACAGGGCATACACCTTCGCTTCAAGGATTGAGGCTCACCTTAAAAAGAATAAGGTGGATC
TGATAACCATTGAGGAACTGGTTGAAATCGTCTCTGAACATCTCAGGAAGGAGGACCCCGAGGTTGCAGAGAAGTACATG
CTCTGGCGAAAGATAAGACAGTGCAAGGAGCCCCTCATAATACTCATAGGCGGTGCTTCAGGTGTGGGAACATCATCAAT
CGCCTTTGAAGTTGCAAACCGCCTTGGAATAAGGAACATGATAAGTACCGACATGATAAGAGAGGTCATGCGTAAGATAG
TCTCCAGGGAACTTCTTCCATCCATCTACGAATCCAGCTACACAGCCTACCAGTCCCTCAGGATACCCCCACCACCGGAA
CTAGACGAGGTCCTCATAGGATTCAGGGACCACGTTGAAAGTGTGAGCATAGGTGTGGAGGCAGTAATTGAGAGGGCGCT
GACAGAGGGGATAAGCATAGTTATTGAGGGCGTGCACATAGTCCCTGGTTTCATAAGGGAGGACCTTGTTAACAAGGAAA
ACGTTGCAATGTTTGTCCTGACGGTCTCTGATGAGAACGTTCATAAGGGGAGGTTCTATTCACGCTGCAGGCAGATGTGG
GCCAGAAGACCCCTTAAAAGATACATAAGTTACTTCTGGGCCATCAGAAGGATTCACAGATACATAGAAAACCAGGCACG
AAAACACGGTGTGCCTGTAATTGAGAACATAGATGTTGTAACAACAATTGACTCGATCATCAAATCATTAACAAAGACAA
CTGTTAAAGGAGGAGAAAAAGGTGCTGAAAAGACTGAATGA

Upstream 100 bases:

>100_bases
ATGATGGCTCCGTAAGGGCCGAAATCTTAAACCTCAAATCCAGTTAAATATATAAAAACTGGATTCCAGATTATCACTGA
ATTCTTTTTGAGGTGAGATC

Downstream 100 bases:

>100_bases
GGTTAAGGTTGAGGATGTAATGACACGTGATGTTATAACAGTCGAGCCATCTGAGGATGTCGTTTTTGCATTTGAAAAAC
TGATGAAGCACAGGATAAGC

Product: 2-phosphoglycerate kinase

Products: NA

Alternate protein names: 2PGK

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MIMVQGEVSGKKYTEPFSKGVLARSLTRAEMDPNRAYTFASRIEAHLKKNKVDLITIEELVEIVSEHLRKEDPEVAEKYM
LWRKIRQCKEPLIILIGGASGVGTSSIAFEVANRLGIRNMISTDMIREVMRKIVSRELLPSIYESSYTAYQSLRIPPPPE
LDEVLIGFRDHVESVSIGVEAVIERALTEGISIVIEGVHIVPGFIREDLVNKENVAMFVLTVSDENVHKGRFYSRCRQMW
ARRPLKRYISYFWAIRRIHRYIENQARKHGVPVIENIDVVTTIDSIIKSLTKTTVKGGEKGAEKTE

Sequences:

>Translated_306_residues
MIMVQGEVSGKKYTEPFSKGVLARSLTRAEMDPNRAYTFASRIEAHLKKNKVDLITIEELVEIVSEHLRKEDPEVAEKYM
LWRKIRQCKEPLIILIGGASGVGTSSIAFEVANRLGIRNMISTDMIREVMRKIVSRELLPSIYESSYTAYQSLRIPPPPE
LDEVLIGFRDHVESVSIGVEAVIERALTEGISIVIEGVHIVPGFIREDLVNKENVAMFVLTVSDENVHKGRFYSRCRQMW
ARRPLKRYISYFWAIRRIHRYIENQARKHGVPVIENIDVVTTIDSIIKSLTKTTVKGGEKGAEKTE
>Mature_306_residues
MIMVQGEVSGKKYTEPFSKGVLARSLTRAEMDPNRAYTFASRIEAHLKKNKVDLITIEELVEIVSEHLRKEDPEVAEKYM
LWRKIRQCKEPLIILIGGASGVGTSSIAFEVANRLGIRNMISTDMIREVMRKIVSRELLPSIYESSYTAYQSLRIPPPPE
LDEVLIGFRDHVESVSIGVEAVIERALTEGISIVIEGVHIVPGFIREDLVNKENVAMFVLTVSDENVHKGRFYSRCRQMW
ARRPLKRYISYFWAIRRIHRYIENQARKHGVPVIENIDVVTTIDSIIKSLTKTTVKGGEKGAEKTE

Specific function: Unknown

COG id: COG2074

COG function: function code G; 2-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PGK2_METTH (O27911)

Other databases:

- EMBL:   AE000666
- PIR:   A69119
- RefSeq:   NP_276989.1
- ProteinModelPortal:   O27911
- STRING:   O27911
- GeneID:   1470968
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH1883
- NMPDR:   fig|187420.1.peg.1844
- eggNOG:   arNOG05968
- HOGENOM:   HBG539723
- OMA:   VIGTDSI
- ProtClustDB:   PRK04220
- BioCyc:   MTHE187420:MTH1883-MONOMER
- HAMAP:   MF_00769
- InterPro:   IPR020872
- InterPro:   IPR005144

Pfam domain/function: PF03477 ATP-cone

EC number: 2.7.2.-

Molecular weight: Translated: 34884; Mature: 34884

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMVQGEVSGKKYTEPFSKGVLARSLTRAEMDPNRAYTFASRIEAHLKKNKVDLITIEEL
CEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEHHHH
VEIVSEHLRKEDPEVAEKYMLWRKIRQCKEPLIILIGGASGVGTSSIAFEVANRLGIRNM
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
ISTDMIREVMRKIVSRELLPSIYESSYTAYQSLRIPPPPELDEVLIGFRDHVESVSIGVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AVIERALTEGISIVIEGVHIVPGFIREDLVNKENVAMFVLTVSDENVHKGRFYSRCRQMW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHH
ARRPLKRYISYFWAIRRIHRYIENQARKHGVPVIENIDVVTTIDSIIKSLTKTTVKGGEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHHHHHHCCCCC
GAEKTE
CCCCCC
>Mature Secondary Structure
MIMVQGEVSGKKYTEPFSKGVLARSLTRAEMDPNRAYTFASRIEAHLKKNKVDLITIEEL
CEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEHHHH
VEIVSEHLRKEDPEVAEKYMLWRKIRQCKEPLIILIGGASGVGTSSIAFEVANRLGIRNM
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
ISTDMIREVMRKIVSRELLPSIYESSYTAYQSLRIPPPPELDEVLIGFRDHVESVSIGVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AVIERALTEGISIVIEGVHIVPGFIREDLVNKENVAMFVLTVSDENVHKGRFYSRCRQMW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHH
ARRPLKRYISYFWAIRRIHRYIENQARKHGVPVIENIDVVTTIDSIIKSLTKTTVKGGEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHHHHHHCCCCC
GAEKTE
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463