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Identifier: 15679857

GI number: 15679857

Start: 1704486

End: 1705724

Strand: Direct

Name: Not Available

Synonym: MTH1869

Alternate gene names: 15679857

Gene position: 1704486-1705724 (Clockwise)

Preceding gene: 15679856

Following gene: 15679858

Centisome position: 97.32

GC content: 53.91

Gene sequence:

>1239_bases
ATGGTTAAAATAGCCCAGATTTCATGCGGAACCGACTACAGCGGTGTTCAGAAGGAAATTGAAAAGGCCGCCGAAACCTT
CGGGGCGGAGATAGTGATCCCCGAGGCTGACCTCGACTACATAGATGAGGCCTATGAAAAGTTCGGGTTCAACTGTGCCA
GCTCAAGCATAAAACTGATGATAGCCAGGGCAATGTCCCTAGTGGAGGGTAAAACAGATGCCGACGCAGTCTTCATAGCA
ACTTGCTTCAGATGTGCCGAGGGCGCCCTTGTAAGGAATGAGCTCAGGAGGTTCATCCAGCAGAACACCAGACTGCCAGT
GGTAACCTACTCATTCACAGAGAGGACCAAGGCAGATGAACTGTTCATACGTATGGAGGCCCTGGCCACCATAGTCGCAA
GGAAGAGCATACTGGCAAGGGAGAAACAGGAGGGCCTCACCCTGGGTATCGACTCAGGATCAACAACAACCAAGGTTGTA
CTCATGGAGGATAATGAGGTCATAGGTACCGGGTGGCTGCCAACAACCGATGTCATAGGTTCAGCAGAGAAGGGCATAGA
GGAGGCACTCTCAGGGACCGGCTACAAACTTGAGGATATTGATGGAATGGGTGTCACAGGATACGGTAGACTCACAATAG
GGAAGCACTACGGGGCGGACCTAATCCAGGAGGAGCTGAGCGTCAACTCCAAGGGTGCGGTGTTCCTGGCAGACCACCAG
AAGGGAGAGGCAACGGTGCTGGACATAGGTGGTATGGACAACAAGGTCATCACGGTCAACGATGGCATACCAGACAACTT
CACCATGGGGGGTATCTGTGCCGGTGCCTCCGGCCGTTTCCTTGAGATAACCGCCAGGAGACTCGGCGTGGAGATAGATG
AGCTCGGAAGCCTCGCCCTCAAGGGCACTTACAGGAAGGCCCTTCTGAACAGCTACTGCATAGTCTTCGGTATACAGGAC
CTTGTCACAGCCCTGGCAGCAGGGACCTCCCGCGAGGATGCAGCAGCGGCAGCATGTCACTCTGTGGCTGAACAGGTCTA
CGAGCAACAGCTTCAGGAAATAGATGTCAGGGAGCCCCTCATACAGGTTGGAGGAACATCACTTATAGAGGGCCTTGTCA
AGGCAGTCAGCGACATCCTTGGAGGTATAGATGTCATAGTGCCCCCATACTCACAGCACATCGGTGCAGTGGGAGCGGCG
CTCCTTGTTTCAGGGATGAAGAAGGCCGGTGAGGGTTAA

Upstream 100 bases:

>100_bases
GGCATACCAACCCTTGAACTTAAATATCCCCGCACACGTGAGGAGACAATAGATGTTGTCAATAAGATAAATAATTTCTT
AGATGAACTGGAGGCTCAAA

Downstream 100 bases:

>100_bases
TATGGGGATACAGATAGAATGCTATGACCCCCGCGGGGCAGCGGTGTACGACATAATCACCAGGCAGGTTCTCCAGGACC
TGCAGCTTTCAAGGGCCATA

Product: activator of (R)-2-hydroxyglutaryl-CoA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MVKIAQISCGTDYSGVQKEIEKAAETFGAEIVIPEADLDYIDEAYEKFGFNCASSSIKLMIARAMSLVEGKTDADAVFIA
TCFRCAEGALVRNELRRFIQQNTRLPVVTYSFTERTKADELFIRMEALATIVARKSILAREKQEGLTLGIDSGSTTTKVV
LMEDNEVIGTGWLPTTDVIGSAEKGIEEALSGTGYKLEDIDGMGVTGYGRLTIGKHYGADLIQEELSVNSKGAVFLADHQ
KGEATVLDIGGMDNKVITVNDGIPDNFTMGGICAGASGRFLEITARRLGVEIDELGSLALKGTYRKALLNSYCIVFGIQD
LVTALAAGTSREDAAAAACHSVAEQVYEQQLQEIDVREPLIQVGGTSLIEGLVKAVSDILGGIDVIVPPYSQHIGAVGAA
LLVSGMKKAGEG

Sequences:

>Translated_412_residues
MVKIAQISCGTDYSGVQKEIEKAAETFGAEIVIPEADLDYIDEAYEKFGFNCASSSIKLMIARAMSLVEGKTDADAVFIA
TCFRCAEGALVRNELRRFIQQNTRLPVVTYSFTERTKADELFIRMEALATIVARKSILAREKQEGLTLGIDSGSTTTKVV
LMEDNEVIGTGWLPTTDVIGSAEKGIEEALSGTGYKLEDIDGMGVTGYGRLTIGKHYGADLIQEELSVNSKGAVFLADHQ
KGEATVLDIGGMDNKVITVNDGIPDNFTMGGICAGASGRFLEITARRLGVEIDELGSLALKGTYRKALLNSYCIVFGIQD
LVTALAAGTSREDAAAAACHSVAEQVYEQQLQEIDVREPLIQVGGTSLIEGLVKAVSDILGGIDVIVPPYSQHIGAVGAA
LLVSGMKKAGEG
>Mature_412_residues
MVKIAQISCGTDYSGVQKEIEKAAETFGAEIVIPEADLDYIDEAYEKFGFNCASSSIKLMIARAMSLVEGKTDADAVFIA
TCFRCAEGALVRNELRRFIQQNTRLPVVTYSFTERTKADELFIRMEALATIVARKSILAREKQEGLTLGIDSGSTTTKVV
LMEDNEVIGTGWLPTTDVIGSAEKGIEEALSGTGYKLEDIDGMGVTGYGRLTIGKHYGADLIQEELSVNSKGAVFLADHQ
KGEATVLDIGGMDNKVITVNDGIPDNFTMGGICAGASGRFLEITARRLGVEIDELGSLALKGTYRKALLNSYCIVFGIQD
LVTALAAGTSREDAAAAACHSVAEQVYEQQLQEIDVREPLIQVGGTSLIEGLVKAVSDILGGIDVIVPPYSQHIGAVGAA
LLVSGMKKAGEG

Specific function: Unknown

COG id: COG1924

COG function: function code I; Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI87082426, Length=257, Percent_Identity=31.5175097276265, Blast_Score=100, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002731
- InterPro:   IPR008275
- InterPro:   IPR017676 [H]

Pfam domain/function: PF01869 BcrAD_BadFG [H]

EC number: NA

Molecular weight: Translated: 43851; Mature: 43851

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKIAQISCGTDYSGVQKEIEKAAETFGAEIVIPEADLDYIDEAYEKFGFNCASSSIKLM
CEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCCCCHHHHHH
IARAMSLVEGKTDADAVFIATCFRCAEGALVRNELRRFIQQNTRLPVVTYSFTERTKADE
HHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHH
LFIRMEALATIVARKSILAREKQEGLTLGIDSGSTTTKVVLMEDNEVIGTGWLPTTDVIG
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEEEECCEEEECCCCCHHHHHC
SAEKGIEEALSGTGYKLEDIDGMGVTGYGRLTIGKHYGADLIQEELSVNSKGAVFLADHQ
CHHHHHHHHHCCCCCEEECCCCCCCCCCCEEEECCCCCHHHHHHHHCCCCCCEEEEEECC
KGEATVLDIGGMDNKVITVNDGIPDNFTMGGICAGASGRFLEITARRLGVEIDELGSLAL
CCCEEEEEECCCCCEEEEEECCCCCCCCCCCEEECCCCCEEEEEHHHHCCCHHHHCCHHH
KGTYRKALLNSYCIVFGIQDLVTALAAGTSREDAAAAACHSVAEQVYEQQLQEIDVREPL
HHHHHHHHHHHHHHEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
IQVGGTSLIEGLVKAVSDILGGIDVIVPPYSQHIGAVGAALLVSGMKKAGEG
HHHCCHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVKIAQISCGTDYSGVQKEIEKAAETFGAEIVIPEADLDYIDEAYEKFGFNCASSSIKLM
CEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCCCCHHHHHH
IARAMSLVEGKTDADAVFIATCFRCAEGALVRNELRRFIQQNTRLPVVTYSFTERTKADE
HHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHH
LFIRMEALATIVARKSILAREKQEGLTLGIDSGSTTTKVVLMEDNEVIGTGWLPTTDVIG
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEEEECCEEEECCCCCHHHHHC
SAEKGIEEALSGTGYKLEDIDGMGVTGYGRLTIGKHYGADLIQEELSVNSKGAVFLADHQ
CHHHHHHHHHCCCCCEEECCCCCCCCCCCEEEECCCCCHHHHHHHHCCCCCCEEEEEECC
KGEATVLDIGGMDNKVITVNDGIPDNFTMGGICAGASGRFLEITARRLGVEIDELGSLAL
CCCEEEEEECCCCCEEEEEECCCCCCCCCCCEEECCCCCEEEEEHHHHCCCHHHHCCHHH
KGTYRKALLNSYCIVFGIQDLVTALAAGTSREDAAAAACHSVAEQVYEQQLQEIDVREPL
HHHHHHHHHHHHHHEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
IQVGGTSLIEGLVKAVSDILGGIDVIVPPYSQHIGAVGAALLVSGMKKAGEG
HHHCCHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]