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Identifier: 15679853

GI number: 15679853

Start: 1701679

End: 1703247

Strand: Direct

Name: Not Available

Synonym: MTH1865

Alternate gene names: NA

Gene position: 1701679-1703247 (Clockwise)

Preceding gene: 15679852

Following gene: 15679854

Centisome position: 97.16

GC content: 50.29

Gene sequence:

>1569_bases
GTGAAGAAAGTCTATGAGGGAGAAATCATGTTTGTTAAGGTCAACGGGGAGGAAGTAGAACTTCCGGATGGATCCACGGT
GAGGGATGCCCTTGAGGCAACCGGCGCCCCCTACGTGGAGGGGACACTGGTGTGCCTCATAAGCGGTACAAGGGAACTTG
AGAGGACGATAGACACATACCGCATCAGGACAACGACAGGCAGCATACTTCTGGAACTTCTGCCGGACGATGCACCTGGC
ATAGTAGAGGAATGGCGAAGGATCTACACTGAGCTTGAAAACATGCGCATCAGGTGGACCACACCATCTGAGATCGCAAT
GGGGCCCCTAAGGACAGAACTGGAACCCTCAAGGGACGAATTCACCTACGATGAAGATGAGGTTATAATGAGCCTCTCAG
GATTCAGCCCGGATTCAACACATATAATAATATCAAAGGAACCCCATTCAGCAGTATACGGTGTCCCAAGGGAGAACAGA
GGAGTATTTGCAAGGATAACCGGGGGAAAAAGGACAGTTGAGAGGTTAACCCAGGATGACGTGGTTAAATCGGTTGAACC
CGTTGTTGAGAGGAAGAGCATAGTTGAGAGCGCCGCTGTAACAGACCTCAACACGGAACTTGAGGATGGAAACCAGCTCT
TCACCTACGTGAAGGTTAAACCCTCCCCTGAATCACCACAGTCAGTGGAACATTTCTTCTCCATGGTGGAGGACGGGAAA
CTCAGGGTTGACTACGAGGCAAATTCATTCATAGGCTTTTACTCACTCCAGGGGATAAAAAAAGACCCCGAAAAAATCGA
CAAGAGAAACCGTGGAGCAGTGACACTCAGAAACACGGGAAGGGGCTCTGGAAGGGTCTACATCTACAGGGAGGATAGGG
TTTCAACCCCATCCCATAACCTCATAGGCCATGTCACAGAGGGCATGGAACTGGTTGACATAGCAGGCGAGGGCGACCAG
ATAACAGTGGAATGCGAACCCGGAAGGATAATGACCGTGGCCATGACCCAGAAGGAGGCTGAGGATTACCTCAGGGAATA
CGGTATAGAACAGATACGTGAGGGTATAATGGACGATGATGCCATTGTGGTGGTCCAGGACCCACCCTACACCATGGACA
TCCTGAGGGAGGGAAAGGTCAGGACCCTTGGCATTGATCCGGATAAGATTCTTGAGATAGAACTTGATCCGGCTGCCCCC
AGATCCTCATGGTACTTCCGCAGGCTCACAGGTCTCATCGACACACCGATAGGATCCCTCAAGGTACACTTCGCCTTCCC
TGGAATGAAGGTGGTCATGTTTGAGGGCGATAAATCACTGGCAAAGGGCCTCATACCTGAAAATACACCTGAGAGATGCG
TTAAGAAGGGTAACATAGGCATAACCAACATGTCACGGCGCCACATAGGCATGGTGGGTGTCAGACTCGAAGACAACGAT
GAATATGGCCCCACAGGGGAACCATTCAATGGCACCAACATGATAGGTAAAATCACAGGTGGAATTGAGAATGTTGAAAA
ACTGAAAGAGGGGGATACCGTATATGTCCGGGAAAGAAAAAGAGGGTGA

Upstream 100 bases:

>100_bases
GAGGGGGTCCTCTTTGACCTTAAAAGTGAAATAATAACAGGAGTGACCGAGGAGAGATTGTGAAAGATTATGTGGAGATT
GATTTGGGGAAACAGGTTGA

Downstream 100 bases:

>100_bases
AAAGGCAACCAGGATGATAATACTGGGCCCATCGGCGAGGCTGAGTTCATCGGAACTTGTCCAGAAACTCCACCTCCTTG
GCCTTCCCCTCACAATAAAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 522; Mature: 522

Protein sequence:

>522_residues
MKKVYEGEIMFVKVNGEEVELPDGSTVRDALEATGAPYVEGTLVCLISGTRELERTIDTYRIRTTTGSILLELLPDDAPG
IVEEWRRIYTELENMRIRWTTPSEIAMGPLRTELEPSRDEFTYDEDEVIMSLSGFSPDSTHIIISKEPHSAVYGVPRENR
GVFARITGGKRTVERLTQDDVVKSVEPVVERKSIVESAAVTDLNTELEDGNQLFTYVKVKPSPESPQSVEHFFSMVEDGK
LRVDYEANSFIGFYSLQGIKKDPEKIDKRNRGAVTLRNTGRGSGRVYIYREDRVSTPSHNLIGHVTEGMELVDIAGEGDQ
ITVECEPGRIMTVAMTQKEAEDYLREYGIEQIREGIMDDDAIVVVQDPPYTMDILREGKVRTLGIDPDKILEIELDPAAP
RSSWYFRRLTGLIDTPIGSLKVHFAFPGMKVVMFEGDKSLAKGLIPENTPERCVKKGNIGITNMSRRHIGMVGVRLEDND
EYGPTGEPFNGTNMIGKITGGIENVEKLKEGDTVYVRERKRG

Sequences:

>Translated_522_residues
MKKVYEGEIMFVKVNGEEVELPDGSTVRDALEATGAPYVEGTLVCLISGTRELERTIDTYRIRTTTGSILLELLPDDAPG
IVEEWRRIYTELENMRIRWTTPSEIAMGPLRTELEPSRDEFTYDEDEVIMSLSGFSPDSTHIIISKEPHSAVYGVPRENR
GVFARITGGKRTVERLTQDDVVKSVEPVVERKSIVESAAVTDLNTELEDGNQLFTYVKVKPSPESPQSVEHFFSMVEDGK
LRVDYEANSFIGFYSLQGIKKDPEKIDKRNRGAVTLRNTGRGSGRVYIYREDRVSTPSHNLIGHVTEGMELVDIAGEGDQ
ITVECEPGRIMTVAMTQKEAEDYLREYGIEQIREGIMDDDAIVVVQDPPYTMDILREGKVRTLGIDPDKILEIELDPAAP
RSSWYFRRLTGLIDTPIGSLKVHFAFPGMKVVMFEGDKSLAKGLIPENTPERCVKKGNIGITNMSRRHIGMVGVRLEDND
EYGPTGEPFNGTNMIGKITGGIENVEKLKEGDTVYVRERKRG
>Mature_522_residues
MKKVYEGEIMFVKVNGEEVELPDGSTVRDALEATGAPYVEGTLVCLISGTRELERTIDTYRIRTTTGSILLELLPDDAPG
IVEEWRRIYTELENMRIRWTTPSEIAMGPLRTELEPSRDEFTYDEDEVIMSLSGFSPDSTHIIISKEPHSAVYGVPRENR
GVFARITGGKRTVERLTQDDVVKSVEPVVERKSIVESAAVTDLNTELEDGNQLFTYVKVKPSPESPQSVEHFFSMVEDGK
LRVDYEANSFIGFYSLQGIKKDPEKIDKRNRGAVTLRNTGRGSGRVYIYREDRVSTPSHNLIGHVTEGMELVDIAGEGDQ
ITVECEPGRIMTVAMTQKEAEDYLREYGIEQIREGIMDDDAIVVVQDPPYTMDILREGKVRTLGIDPDKILEIELDPAAP
RSSWYFRRLTGLIDTPIGSLKVHFAFPGMKVVMFEGDKSLAKGLIPENTPERCVKKGNIGITNMSRRHIGMVGVRLEDND
EYGPTGEPFNGTNMIGKITGGIENVEKLKEGDTVYVRERKRG

Specific function: Unknown

COG id: COG4070

COG function: function code O; Predicted peptidyl-prolyl cis-trans isomerase (rotamase), cyclophilin family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0288 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1865_METTH (O27893)

Other databases:

- EMBL:   AE000666
- PIR:   E69116
- RefSeq:   NP_276971.1
- ProteinModelPortal:   O27893
- STRING:   O27893
- GeneID:   1470950
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH1865
- NMPDR:   fig|187420.1.peg.1826
- eggNOG:   arNOG04950
- HOGENOM:   HBG541903
- OMA:   FKKWDVV
- ProtClustDB:   PRK00969
- BioCyc:   MTHE187420:MTH1865-MONOMER
- HAMAP:   MF_01089
- InterPro:   IPR016466
- PIRSF:   PIRSF005852
- TIGRFAMs:   TIGR03268

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 58535; Mature: 58535

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVYEGEIMFVKVNGEEVELPDGSTVRDALEATGAPYVEGTLVCLISGTRELERTIDTY
CCCEECCEEEEEEECCCEEECCCCCHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHE
RIRTTTGSILLELLPDDAPGIVEEWRRIYTELENMRIRWTTPSEIAMGPLRTELEPSRDE
EEEEECCEEEEEECCCCCCCHHHHHHHHHHHHHCCEEEECCCHHHCCCCCCCCCCCCCCC
FTYDEDEVIMSLSGFSPDSTHIIISKEPHSAVYGVPRENRGVFARITGGKRTVERLTQDD
CCCCCCCEEEEEECCCCCCCEEEEECCCCCCEECCCCCCCCEEEEECCCHHHHHHHHHHH
VVKSVEPVVERKSIVESAAVTDLNTELEDGNQLFTYVKVKPSPESPQSVEHFFSMVEDGK
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHCCCE
LRVDYEANSFIGFYSLQGIKKDPEKIDKRNRGAVTLRNTGRGSGRVYIYREDRVSTPSHN
EEEEECCCCEEEEEEECCCCCCHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCC
LIGHVTEGMELVDIAGEGDQITVECEPGRIMTVAMTQKEAEDYLREYGIEQIREGIMDDD
HHEECCCCCEEEEEECCCCEEEEEECCCEEEEEEECHHHHHHHHHHCCHHHHHHCCCCCC
AIVVVQDPPYTMDILREGKVRTLGIDPDKILEIELDPAAPRSSWYFRRLTGLIDTPIGSL
CEEEECCCCCCHHHHCCCCEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCE
KVHFAFPGMKVVMFEGDKSLAKGLIPENTPERCVKKGNIGITNMSRRHIGMVGVRLEDND
EEEEECCCEEEEEEECCHHHHCCCCCCCCHHHHHHCCCCCEECCCCCCEEEEEEEEECCC
EYGPTGEPFNGTNMIGKITGGIENVEKLKEGDTVYVRERKRG
CCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCEEEEEECCCC
>Mature Secondary Structure
MKKVYEGEIMFVKVNGEEVELPDGSTVRDALEATGAPYVEGTLVCLISGTRELERTIDTY
CCCEECCEEEEEEECCCEEECCCCCHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHE
RIRTTTGSILLELLPDDAPGIVEEWRRIYTELENMRIRWTTPSEIAMGPLRTELEPSRDE
EEEEECCEEEEEECCCCCCCHHHHHHHHHHHHHCCEEEECCCHHHCCCCCCCCCCCCCCC
FTYDEDEVIMSLSGFSPDSTHIIISKEPHSAVYGVPRENRGVFARITGGKRTVERLTQDD
CCCCCCCEEEEEECCCCCCCEEEEECCCCCCEECCCCCCCCEEEEECCCHHHHHHHHHHH
VVKSVEPVVERKSIVESAAVTDLNTELEDGNQLFTYVKVKPSPESPQSVEHFFSMVEDGK
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHCCCE
LRVDYEANSFIGFYSLQGIKKDPEKIDKRNRGAVTLRNTGRGSGRVYIYREDRVSTPSHN
EEEEECCCCEEEEEEECCCCCCHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCC
LIGHVTEGMELVDIAGEGDQITVECEPGRIMTVAMTQKEAEDYLREYGIEQIREGIMDDD
HHEECCCCCEEEEEECCCCEEEEEECCCEEEEEEECHHHHHHHHHHCCHHHHHHCCCCCC
AIVVVQDPPYTMDILREGKVRTLGIDPDKILEIELDPAAPRSSWYFRRLTGLIDTPIGSL
CEEEECCCCCCHHHHCCCCEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCE
KVHFAFPGMKVVMFEGDKSLAKGLIPENTPERCVKKGNIGITNMSRRHIGMVGVRLEDND
EEEEECCCEEEEEEECCHHHHCCCCCCCCHHHHHHCCCCCEECCCCCCEEEEEEEEECCC
EYGPTGEPFNGTNMIGKITGGIENVEKLKEGDTVYVRERKRG
CCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463