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Identifier: 15679795

GI number: 15679795

Start: 1649814

End: 1651358

Strand: Direct

Name: Not Available

Synonym: MTH1807

Alternate gene names: 15679795

Gene position: 1649814-1651358 (Clockwise)

Preceding gene: 15679794

Following gene: 15679796

Centisome position: 94.2

GC content: 48.74

Gene sequence:

>1545_bases
ATGAAGTTTTTATATCTGCTTCAACATAATACTATTAATATGGTCTGTGGTGGTTTTATGAATATTGTGATTGTTGGAGC
TGGATTCGGGGGAATATCTGCAGCGGCACTCCTTGCACAGAAGGGGCTGGAAGTAACTGTCATTGAGAAAAATGAGGGTC
CTGGGGGACGTGCAAGCGTCTACAGTGAGGGGGGATTCACCTTTGACATGGGACCATCATGGTACCTCATGCCAGACGTC
TTTGAAAACTTCTTCGCAGAGTTCAATGCCAGGCCAGAGGATTTCTATGACCTCAAAAAACTTGAACCAGCATACCGCGT
ATTCTTTGACGGGGGAAGGGTAGTTGATGTATCATCTGATATTGAAAAGAACTATGAACTCTTTGACAGCTTTGAGGAAG
ATGGGGGTGAAAGACTCAGGGAGTACCTGGAATCAGCCGGTAAACTCTACGACTCGGTTGTGAAGGAAATGCTCTACAGG
GACTACAGGTCAGTCCTGGACTTCCTTAATGGAAAGCTCCTGCTACAGGGATTGAGGCTCAACATACTCGAATCTCTTGA
ACACTTCGTTAACAGGCGATTTAAGAGTGACGAGGCCCGCAAGATACTCCAGTACTCAATGGGATTCCTTGGAAGCGCAC
CACAGAACACACCCTCAATGTATCATATAATGTCCCATATCGACATGACCCTTGGAGTCTTCTACCCTGAGGGGGGTATA
AGGAGGGTTGCCCAATCAATATATGAACTCGCCCTTGAACATGGAGCCAGATTCCACTTCAACGAGGAGGTTAAAAGGAT
AGAGGTAATCGATGGAGTGGCAACATCTATCATAACCGACAGGAACATCTATGAAGCTGATGCGGTCCTGGTGAATGCGG
ATTACCCCCACAGTGAACTGGAACTTCTTGATGAACCCCACAGGACCTATGATGAGGCATACTGGGAGTCCAGGGTAATG
GCACCATCAGCCTTTGTAGCCTACCTCGGAGTTGACAGGGTTATAGATGCCCTTGAACACCACAACCTCTTCCTGGAGAG
GGACTGGGCCGATAAATTCCAGGAGGTATTTGACCCCCGGAGGGCGAGGTGGCCAGAGAGACCATCCTACTATGTGAATG
TACCATCACGGACAGATACGACTGCTGCCCCCCAGGGATCAGACACCCTCTTCATACTGGTCCCCCTCGCGCCGGGCATG
GAGGATAACGAGGAACTCAGGGAGGGCCTCTACCGGAGGGTCATGGATGACCTTGAGAGGAAGGTGGGTGAAAATATACG
TGACCATGTTGTTGTGAAGAGGATATTCGCCATAAATGATTTCAGGGACCGTTACAATGCATACAGGGGCACAGCCCTGG
GTCTTTCCCATACACTCAGACAGACAGCCCTCTGGAGACCATCACATAAGAGTAAGAAGGTTAAGAACCTCTATTACACG
GGACATTACACCCATCCAGGTATAGGCGTGCCGATGACACTTATCTCCTCCCAGATAGTCTGCAACGAGATGATGGATGA
TATGGGAATTAATCCGGATGGATGA

Upstream 100 bases:

>100_bases
ATCAGAGAGGACATTGTTCATCCACCCCTCCTTTTCACATCATATCTATGCGTCGACACATCACTGTTTCTGCACATTTC
AATAATGAAATATCCATTTA

Downstream 100 bases:

>100_bases
TTTTTACTGTATAAACCTATTAATGGGTGATATAACTTTGATTGACGGGAAAATTTACTCAATATTTAAGCGTGGAAGCA
AAACATACTTCTACAGCACG

Product: phytoene dehydrogenase

Products: NA

Alternate protein names: 4,4'-diapophytoene desaturase; Diapophytoene desaturase [H]

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MKFLYLLQHNTINMVCGGFMNIVIVGAGFGGISAAALLAQKGLEVTVIEKNEGPGGRASVYSEGGFTFDMGPSWYLMPDV
FENFFAEFNARPEDFYDLKKLEPAYRVFFDGGRVVDVSSDIEKNYELFDSFEEDGGERLREYLESAGKLYDSVVKEMLYR
DYRSVLDFLNGKLLLQGLRLNILESLEHFVNRRFKSDEARKILQYSMGFLGSAPQNTPSMYHIMSHIDMTLGVFYPEGGI
RRVAQSIYELALEHGARFHFNEEVKRIEVIDGVATSIITDRNIYEADAVLVNADYPHSELELLDEPHRTYDEAYWESRVM
APSAFVAYLGVDRVIDALEHHNLFLERDWADKFQEVFDPRRARWPERPSYYVNVPSRTDTTAAPQGSDTLFILVPLAPGM
EDNEELREGLYRRVMDDLERKVGENIRDHVVVKRIFAINDFRDRYNAYRGTALGLSHTLRQTALWRPSHKSKKVKNLYYT
GHYTHPGIGVPMTLISSQIVCNEMMDDMGINPDG

Sequences:

>Translated_514_residues
MKFLYLLQHNTINMVCGGFMNIVIVGAGFGGISAAALLAQKGLEVTVIEKNEGPGGRASVYSEGGFTFDMGPSWYLMPDV
FENFFAEFNARPEDFYDLKKLEPAYRVFFDGGRVVDVSSDIEKNYELFDSFEEDGGERLREYLESAGKLYDSVVKEMLYR
DYRSVLDFLNGKLLLQGLRLNILESLEHFVNRRFKSDEARKILQYSMGFLGSAPQNTPSMYHIMSHIDMTLGVFYPEGGI
RRVAQSIYELALEHGARFHFNEEVKRIEVIDGVATSIITDRNIYEADAVLVNADYPHSELELLDEPHRTYDEAYWESRVM
APSAFVAYLGVDRVIDALEHHNLFLERDWADKFQEVFDPRRARWPERPSYYVNVPSRTDTTAAPQGSDTLFILVPLAPGM
EDNEELREGLYRRVMDDLERKVGENIRDHVVVKRIFAINDFRDRYNAYRGTALGLSHTLRQTALWRPSHKSKKVKNLYYT
GHYTHPGIGVPMTLISSQIVCNEMMDDMGINPDG
>Mature_514_residues
MKFLYLLQHNTINMVCGGFMNIVIVGAGFGGISAAALLAQKGLEVTVIEKNEGPGGRASVYSEGGFTFDMGPSWYLMPDV
FENFFAEFNARPEDFYDLKKLEPAYRVFFDGGRVVDVSSDIEKNYELFDSFEEDGGERLREYLESAGKLYDSVVKEMLYR
DYRSVLDFLNGKLLLQGLRLNILESLEHFVNRRFKSDEARKILQYSMGFLGSAPQNTPSMYHIMSHIDMTLGVFYPEGGI
RRVAQSIYELALEHGARFHFNEEVKRIEVIDGVATSIITDRNIYEADAVLVNADYPHSELELLDEPHRTYDEAYWESRVM
APSAFVAYLGVDRVIDALEHHNLFLERDWADKFQEVFDPRRARWPERPSYYVNVPSRTDTTAAPQGSDTLFILVPLAPGM
EDNEELREGLYRRVMDDLERKVGENIRDHVVVKRIFAINDFRDRYNAYRGTALGLSHTLRQTALWRPSHKSKKVKNLYYT
GHYTHPGIGVPMTLISSQIVCNEMMDDMGINPDG

Specific function: Catalyzes three successive dehydrogenation reactions that lead to the introduction of three double bonds into dehydrosqualene (4,4'-diapophytoene), with 4,4'-diapophytofluene and 4,4'-diapo-zeta-carotene as intermediates, and 4,4'- diaponeurosporene (the

COG id: COG1233

COG function: function code Q; Phytoene dehydrogenase and related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carotenoid/retinoid oxidoreductase family. CrtN subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002937
- InterPro:   IPR014105 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: NA

Molecular weight: Translated: 58849; Mature: 58849

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLYLLQHNTINMVCGGFMNIVIVGAGFGGISAAALLAQKGLEVTVIEKNEGPGGRASV
CCEEEEEECCCHHHHHHHHEEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCEE
YSEGGFTFDMGPSWYLMPDVFENFFAEFNARPEDFYDLKKLEPAYRVFFDGGRVVDVSSD
ECCCCEEEECCCCEEECHHHHHHHHHHCCCCCCHHHHHHHCCHHHEEEECCCEEEECCHH
IEKNYELFDSFEEDGGERLREYLESAGKLYDSVVKEMLYRDYRSVLDFLNGKLLLQGLRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
NILESLEHFVNRRFKSDEARKILQYSMGFLGSAPQNTPSMYHIMSHIDMTLGVFYPEGGI
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEEEECCHHH
RRVAQSIYELALEHGARFHFNEEVKRIEVIDGVATSIITDRNIYEADAVLVNADYPHSEL
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEECCEEEEECCCCHHHH
ELLDEPHRTYDEAYWESRVMAPSAFVAYLGVDRVIDALEHHNLFLERDWADKFQEVFDPR
HHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHCHH
RARWPERPSYYVNVPSRTDTTAAPQGSDTLFILVPLAPGMEDNEELREGLYRRVMDDLER
HHCCCCCCCEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
KVGENIRDHVVVKRIFAINDFRDRYNAYRGTALGLSHTLRQTALWRPSHKSKKVKNLYYT
HHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHEEEEE
GHYTHPGIGVPMTLISSQIVCNEMMDDMGINPDG
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKFLYLLQHNTINMVCGGFMNIVIVGAGFGGISAAALLAQKGLEVTVIEKNEGPGGRASV
CCEEEEEECCCHHHHHHHHEEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCEE
YSEGGFTFDMGPSWYLMPDVFENFFAEFNARPEDFYDLKKLEPAYRVFFDGGRVVDVSSD
ECCCCEEEECCCCEEECHHHHHHHHHHCCCCCCHHHHHHHCCHHHEEEECCCEEEECCHH
IEKNYELFDSFEEDGGERLREYLESAGKLYDSVVKEMLYRDYRSVLDFLNGKLLLQGLRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
NILESLEHFVNRRFKSDEARKILQYSMGFLGSAPQNTPSMYHIMSHIDMTLGVFYPEGGI
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEEEECCHHH
RRVAQSIYELALEHGARFHFNEEVKRIEVIDGVATSIITDRNIYEADAVLVNADYPHSEL
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEECCEEEEECCCCHHHH
ELLDEPHRTYDEAYWESRVMAPSAFVAYLGVDRVIDALEHHNLFLERDWADKFQEVFDPR
HHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHCHH
RARWPERPSYYVNVPSRTDTTAAPQGSDTLFILVPLAPGMEDNEELREGLYRRVMDDLER
HHCCCCCCCEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
KVGENIRDHVVVKRIFAINDFRDRYNAYRGTALGLSHTLRQTALWRPSHKSKKVKNLYYT
HHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHEEEEE
GHYTHPGIGVPMTLISSQIVCNEMMDDMGINPDG
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA