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Identifier: 15679734

GI number: 15679734

Start: 1593888

End: 1594700

Strand: Direct

Name: Not Available

Synonym: MTH1742

Alternate gene names: 15679734

Gene position: 1593888-1594700 (Clockwise)

Preceding gene: 15679733

Following gene: 15679735

Centisome position: 91.01

GC content: 49.45

Gene sequence:

>813_bases
ATGAGGGATATAAGGAAATATAAGCTGATAGAACGTGGAGACAGGGTACTTGTCGGTTTATCCGGTGGAAAGGACAGCGT
GATGGTCATTGACATCCTTGATGAACTCAGGGAAAGAAACATAATAGAACTTGAGGCAGTCACCATCGATGAGGGTATAG
GCGGGTACCGTGAGGATGGAGTAAGGATCGCCAGGAAAATATGTGCCGACAGAGGCATACCCCACAGGGTTGTCAGTCTG
GAGGACTATGCAGGAATAACACTGGATGAGATAATGAAAAACCCCTCACGGAGCGCATGCACCTACTGCGGAGTGTTCAG
ACGCTGGATACTTAACAGGGAGGCCAGGAAGAGCAAGGCAACGAAGATAGCAACCGGCCACAACCTCGACGATGAGACCC
AGGCAATAGTCATGAATTACCTTGAGGGAAACCTCGAGAACCTCACACGGATAGGCCCCATGACATCATCTGCAGGGGGA
AGGTTCATACCAAAAATCAAGCCCCTGAGGGAGATACCCGAGAAGGAGGTGGCCCTCTATGTACTTGCAAGGGGCCTGGA
CGTTCACCTCGCAGGGTGTCCCTATGCATCAGGTTCATTCAGGAGGGAGATAGGTGACTTCCTGAAGCAGATATCCGTGA
AACGCCCAACCATAATGTACTCAACACTCAGGGGATTCGACAGGATAAAGGAGATCCTCAGAAGGGATTTATCGGAATCA
GGGAGATCAGGTATCTGTGTCAAATGCGGTGAACCTGCATCAGGAAAACTCTGCAAGGCATGCACATTTATAGAGGAATT
AACGAAAAGATGA

Upstream 100 bases:

>100_bases
TGCACCAGATGCGGGATCAGAGGGTGTCATAATAAACAGGAAATACTCAGGACAGCTACTCTGCAGCGACTGCTTCATAG
AGACAACAAGAAAAAAAGTA

Downstream 100 bases:

>100_bases
TGAAACTCCAGTATACATGGTGATAGGGATGAAGTTTACAGTAATCACAGATGACGGAAAGAAAATACTTGAATCAGGGG
CTCCACGAAGGATAAAGGAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MRDIRKYKLIERGDRVLVGLSGGKDSVMVIDILDELRERNIIELEAVTIDEGIGGYREDGVRIARKICADRGIPHRVVSL
EDYAGITLDEIMKNPSRSACTYCGVFRRWILNREARKSKATKIATGHNLDDETQAIVMNYLEGNLENLTRIGPMTSSAGG
RFIPKIKPLREIPEKEVALYVLARGLDVHLAGCPYASGSFRREIGDFLKQISVKRPTIMYSTLRGFDRIKEILRRDLSES
GRSGICVKCGEPASGKLCKACTFIEELTKR

Sequences:

>Translated_270_residues
MRDIRKYKLIERGDRVLVGLSGGKDSVMVIDILDELRERNIIELEAVTIDEGIGGYREDGVRIARKICADRGIPHRVVSL
EDYAGITLDEIMKNPSRSACTYCGVFRRWILNREARKSKATKIATGHNLDDETQAIVMNYLEGNLENLTRIGPMTSSAGG
RFIPKIKPLREIPEKEVALYVLARGLDVHLAGCPYASGSFRREIGDFLKQISVKRPTIMYSTLRGFDRIKEILRRDLSES
GRSGICVKCGEPASGKLCKACTFIEELTKR
>Mature_270_residues
MRDIRKYKLIERGDRVLVGLSGGKDSVMVIDILDELRERNIIELEAVTIDEGIGGYREDGVRIARKICADRGIPHRVVSL
EDYAGITLDEIMKNPSRSACTYCGVFRRWILNREARKSKATKIATGHNLDDETQAIVMNYLEGNLENLTRIGPMTSSAGG
RFIPKIKPLREIPEKEVALYVLARGLDVHLAGCPYASGSFRREIGDFLKQISVKRPTIMYSTLRGFDRIKEILRRDLSES
GRSGICVKCGEPASGKLCKACTFIEELTKR

Specific function: Unknown

COG id: COG0037

COG function: function code D; Predicted ATPase of the PP-loop superfamily implicated in cell cycle control

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TtcA family [H]

Homologues:

Organism=Homo sapiens, GI222537719, Length=268, Percent_Identity=37.3134328358209, Blast_Score=163, Evalue=2e-40,
Organism=Escherichia coli, GI1787606, Length=228, Percent_Identity=29.8245614035088, Blast_Score=85, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17540090, Length=264, Percent_Identity=34.469696969697, Blast_Score=158, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6321227, Length=113, Percent_Identity=42.4778761061947, Blast_Score=86, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24651972, Length=269, Percent_Identity=34.9442379182156, Blast_Score=164, Evalue=7e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012089
- InterPro:   IPR014729
- InterPro:   IPR011063
- InterPro:   IPR000541
- InterPro:   IPR020554 [H]

Pfam domain/function: PF01171 ATP_bind_3 [H]

EC number: NA

Molecular weight: Translated: 30293; Mature: 30293

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDIRKYKLIERGDRVLVGLSGGKDSVMVIDILDELRERNIIELEAVTIDEGIGGYREDG
CCCHHHHHHHHCCCEEEEEECCCCCCEEEEHHHHHHHHCCEEEEEEEEECCCCCCCHHHH
VRIARKICADRGIPHRVVSLEDYAGITLDEIMKNPSRSACTYCGVFRRWILNREARKSKA
HHHHHHHHHCCCCCCEEEEEHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHH
TKIATGHNLDDETQAIVMNYLEGNLENLTRIGPMTSSAGGRFIPKIKPLREIPEKEVALY
HEEECCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCHHHHCCHHHHHHH
VLARGLDVHLAGCPYASGSFRREIGDFLKQISVKRPTIMYSTLRGFDRIKEILRRDLSES
HHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GRSGICVKCGEPASGKLCKACTFIEELTKR
CCCCEEEECCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRDIRKYKLIERGDRVLVGLSGGKDSVMVIDILDELRERNIIELEAVTIDEGIGGYREDG
CCCHHHHHHHHCCCEEEEEECCCCCCEEEEHHHHHHHHCCEEEEEEEEECCCCCCCHHHH
VRIARKICADRGIPHRVVSLEDYAGITLDEIMKNPSRSACTYCGVFRRWILNREARKSKA
HHHHHHHHHCCCCCCEEEEEHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHH
TKIATGHNLDDETQAIVMNYLEGNLENLTRIGPMTSSAGGRFIPKIKPLREIPEKEVALY
HEEECCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCHHHHCCHHHHHHH
VLARGLDVHLAGCPYASGSFRREIGDFLKQISVKRPTIMYSTLRGFDRIKEILRRDLSES
HHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GRSGICVKCGEPASGKLCKACTFIEELTKR
CCCCEEEECCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]