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Identifier: 15679704

GI number: 15679704

Start: 1566679

End: 1568061

Strand: Direct

Name: Not Available

Synonym: MTH1710

Alternate gene names: 15679704

Gene position: 1566679-1568061 (Clockwise)

Preceding gene: 15679703

Following gene: 15679705

Centisome position: 89.45

GC content: 51.19

Gene sequence:

>1383_bases
ATGTTTGAAGACATACCAGTCGATGTAAGTCCCATGCATGAGGGGGAGAGGATAAGATCAGCCAACATGTTCGTTGAACT
GGCAGGTCCCAAATCCATCGGAGCAGAACTGGTCCAGGTTAAGGACGAGGTCGAGGACGGAAAGGTGGAGGTCAAGGGGC
CCGAGATAGATGAAATGGAACAGGGCCAGGTGTACCCCTTCGCCATAAACGTTGAGGTAGCTGGCAGTGAACTCGAGGAG
GAACTTGAAAGCGTCATCGAGAGGAGGCTCCATGAGCTCTGCAACTATGTTAAGGGATTCATGCACCTCAACCAGAGGGA
CCAGATATGGTGTCGTGTGAGTACAGAGGCAAAGGATGCAGGTTTCAGGCTCGAACACCTCGGAAAGGCGCTCTCGGTCC
TCTTCAGGGAGGAGTTCCCCATAATCGAATCAATAGCAGTAACACTCATGACAGATGAGGCAGCGGTCCAGGAATTCCTT
GAGACAGCAAGGGAGAAGTATGAGACCAGGGACTCAAGGGCAAGGGAACTTTCAGATGAGGACGTTGATGTCTTCTATGG
ATGTCTCATGTGTCAGTCCTTCGCACCCACACATGTATGCATAGTAACACCAGACAGGACAGCCCTCTGCGGCGCCATAA
ACTGGTTCGACTGCCGTGCAGCATACAAGATGGACCCTGACGGCCCGATATTCGAAATTGAAAAGGGTGAAGTCCTGGAC
CCTGAGAGGGGAGAATATGCAAATGTTAACGCTGCAGTAGAAGAAAATTCCCAGGGCACAACAGATAGGGTATACCTCCA
CAGTGTCTTCGGTTACCCACACACATCCTGCGGATGCTTCGAGGCAGTGGCATTCTACATACCTGAACTTGATGGTATAG
GTATTGTTAACAGGGACTTCAGGGGAGAAACGCCCCTCGGGATACCATTCTCAGCAATGGCCGGGCAGTGTTCAGGAGGA
AAACAGGTTGAAGGTTTCTCAGGTCTCAGCCTTGAATACATGAGGTCACCCAAATTCCTCCAGGCAGACGGAGGATACCA
CAGGGTGATCTGGATGCCAAGGGAGCTCAAGGAATCTGTTCTGGAATTCATCCCGGAAGACGTCCGGGACAAGATTGCAA
CGGAGGAGGATGCAACATCAATAAAGGATCTCAGAAGATTCCTGAGGGATAATGAACACCCTGTCCTTGAAAGGGCGGCC
GTTGAAGAAACTGAACCCGAAGAAGAGGAGGTTGAGGAGGCATACCCTGAGGAGACCCCGATTCCAGAGGGGGTCCCTGT
AATGGCAGCACCTGAGATGACCCTCCCTGCAGCCGGAGGATTCAGAATAGTCCTCAAGAATGCAAAGATCTACGCTGAGA
AGGTAATAATAAAGCGCAAATAA

Upstream 100 bases:

>100_bases
CTCAAATGCAGATGCATCATTCCCGAACATGGATGATGATGAATGGTTCAGATACCTTGAGAAGATGTATGCTGAATGAT
CAGGATAATGGAGGAATTCA

Downstream 100 bases:

>100_bases
ACCCCTCATGAGTGGTCACGTGATAATAGCAGTAAGTGGCAAGGGCGGCACGGGAAAAACGATGTTCTCAGCTTCCCTCA
TAAGGGTCCTGGCATCAACG

Product: acetyl-CoA decarbonylase/synthase complex subunit beta

Products: CO2; AH2

Alternate protein names: ACDS complex subunit beta; ACDS complex acyltransferase

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MFEDIPVDVSPMHEGERIRSANMFVELAGPKSIGAELVQVKDEVEDGKVEVKGPEIDEMEQGQVYPFAINVEVAGSELEE
ELESVIERRLHELCNYVKGFMHLNQRDQIWCRVSTEAKDAGFRLEHLGKALSVLFREEFPIIESIAVTLMTDEAAVQEFL
ETAREKYETRDSRARELSDEDVDVFYGCLMCQSFAPTHVCIVTPDRTALCGAINWFDCRAAYKMDPDGPIFEIEKGEVLD
PERGEYANVNAAVEENSQGTTDRVYLHSVFGYPHTSCGCFEAVAFYIPELDGIGIVNRDFRGETPLGIPFSAMAGQCSGG
KQVEGFSGLSLEYMRSPKFLQADGGYHRVIWMPRELKESVLEFIPEDVRDKIATEEDATSIKDLRRFLRDNEHPVLERAA
VEETEPEEEEVEEAYPEETPIPEGVPVMAAPEMTLPAAGGFRIVLKNAKIYAEKVIIKRK

Sequences:

>Translated_460_residues
MFEDIPVDVSPMHEGERIRSANMFVELAGPKSIGAELVQVKDEVEDGKVEVKGPEIDEMEQGQVYPFAINVEVAGSELEE
ELESVIERRLHELCNYVKGFMHLNQRDQIWCRVSTEAKDAGFRLEHLGKALSVLFREEFPIIESIAVTLMTDEAAVQEFL
ETAREKYETRDSRARELSDEDVDVFYGCLMCQSFAPTHVCIVTPDRTALCGAINWFDCRAAYKMDPDGPIFEIEKGEVLD
PERGEYANVNAAVEENSQGTTDRVYLHSVFGYPHTSCGCFEAVAFYIPELDGIGIVNRDFRGETPLGIPFSAMAGQCSGG
KQVEGFSGLSLEYMRSPKFLQADGGYHRVIWMPRELKESVLEFIPEDVRDKIATEEDATSIKDLRRFLRDNEHPVLERAA
VEETEPEEEEVEEAYPEETPIPEGVPVMAAPEMTLPAAGGFRIVLKNAKIYAEKVIIKRK
>Mature_460_residues
MFEDIPVDVSPMHEGERIRSANMFVELAGPKSIGAELVQVKDEVEDGKVEVKGPEIDEMEQGQVYPFAINVEVAGSELEE
ELESVIERRLHELCNYVKGFMHLNQRDQIWCRVSTEAKDAGFRLEHLGKALSVLFREEFPIIESIAVTLMTDEAAVQEFL
ETAREKYETRDSRARELSDEDVDVFYGCLMCQSFAPTHVCIVTPDRTALCGAINWFDCRAAYKMDPDGPIFEIEKGEVLD
PERGEYANVNAAVEENSQGTTDRVYLHSVFGYPHTSCGCFEAVAFYIPELDGIGIVNRDFRGETPLGIPFSAMAGQCSGG
KQVEGFSGLSLEYMRSPKFLQADGGYHRVIWMPRELKESVLEFIPEDVRDKIATEEDATSIKDLRRFLRDNEHPVLERAA
VEETEPEEEEVEEAYPEETPIPEGVPVMAAPEMTLPAAGGFRIVLKNAKIYAEKVIIKRK

Specific function: Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2)

COG id: COG1614

COG function: function code C; CO dehydrogenase/acetyl-CoA synthase beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CdhC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACDB_METTH (O27745)

Other databases:

- EMBL:   AE000666
- PIR:   H69095
- RefSeq:   NP_276822.1
- ProteinModelPortal:   O27745
- SMR:   O27745
- STRING:   O27745
- GeneID:   1470795
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH1710
- NMPDR:   fig|187420.1.peg.1677
- eggNOG:   arNOG04919
- HOGENOM:   HBG456963
- OMA:   DRPALCG
- ProtClustDB:   PRK04456
- BioCyc:   MTHE187420:MTH1710-MONOMER
- HAMAP:   MF_01138
- InterPro:   IPR004461
- InterPro:   IPR011254
- TIGRFAMs:   TIGR00316

Pfam domain/function: PF03598 CdhC; SSF56821 Prismane_like

EC number: 1.2.99.2

Molecular weight: Translated: 51738; Mature: 51738

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEDIPVDVSPMHEGERIRSANMFVELAGPKSIGAELVQVKDEVEDGKVEVKGPEIDEME
CCCCCCCCCCCCCCCCCEEECCEEEEECCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCC
QGQVYPFAINVEVAGSELEEELESVIERRLHELCNYVKGFMHLNQRDQIWCRVSTEAKDA
CCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCC
GFRLEHLGKALSVLFREEFPIIESIAVTLMTDEAAVQEFLETAREKYETRDSRARELSDE
CCCHHHHHHHHHHHHHHCCCHHHHHEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DVDVFYGCLMCQSFAPTHVCIVTPDRTALCGAINWFDCRAAYKMDPDGPIFEIEKGEVLD
CHHHHHHHHHHHCCCCCEEEEECCCCCCHHCCCCCCCCCEEEEECCCCCEEEECCCCCCC
PERGEYANVNAAVEENSQGTTDRVYLHSVFGYPHTSCGCFEAVAFYIPELDGIGIVNRDF
CCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCEECCCC
RGETPLGIPFSAMAGQCSGGKQVEGFSGLSLEYMRSPKFLQADGGYHRVIWMPRELKESV
CCCCCCCCCHHHHCCCCCCCCCCCCCCCCCHHHHCCCCEEECCCCEEEEEECCHHHHHHH
LEFIPEDVRDKIATEEDATSIKDLRRFLRDNEHPVLERAAVEETEPEEEEVEEAYPEETP
HHHCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHCCCCCC
IPEGVPVMAAPEMTLPAAGGFRIVLKNAKIYAEKVIIKRK
CCCCCCEEECCCCCCCCCCCEEEEEECCCEEEEEEEEECC
>Mature Secondary Structure
MFEDIPVDVSPMHEGERIRSANMFVELAGPKSIGAELVQVKDEVEDGKVEVKGPEIDEME
CCCCCCCCCCCCCCCCCEEECCEEEEECCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCC
QGQVYPFAINVEVAGSELEEELESVIERRLHELCNYVKGFMHLNQRDQIWCRVSTEAKDA
CCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCC
GFRLEHLGKALSVLFREEFPIIESIAVTLMTDEAAVQEFLETAREKYETRDSRARELSDE
CCCHHHHHHHHHHHHHHCCCHHHHHEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DVDVFYGCLMCQSFAPTHVCIVTPDRTALCGAINWFDCRAAYKMDPDGPIFEIEKGEVLD
CHHHHHHHHHHHCCCCCEEEEECCCCCCHHCCCCCCCCCEEEEECCCCCEEEECCCCCCC
PERGEYANVNAAVEENSQGTTDRVYLHSVFGYPHTSCGCFEAVAFYIPELDGIGIVNRDF
CCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCEECCCC
RGETPLGIPFSAMAGQCSGGKQVEGFSGLSLEYMRSPKFLQADGGYHRVIWMPRELKESV
CCCCCCCCCHHHHCCCCCCCCCCCCCCCCCHHHHCCCCEEECCCCEEEEEECCHHHHHHH
LEFIPEDVRDKIATEEDATSIKDLRRFLRDNEHPVLERAAVEETEPEEEEVEEAYPEETP
HHHCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHCCCCCC
IPEGVPVMAAPEMTLPAAGGFRIVLKNAKIYAEKVIIKRK
CCCCCCEEECCCCCCCCCCCEEEEEECCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: CO; H2O; A

Specific reaction: CO + H2O + A = CO2 + AH2

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463