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The map label for this gene is rpl12p

Identifier: 15679676

GI number: 15679676

Start: 1539722

End: 1540027

Strand: Direct

Name: rpl12p

Synonym: MTH1682

Alternate gene names: 15679676

Gene position: 1539722-1540027 (Clockwise)

Preceding gene: 15679675

Following gene: 15679677

Centisome position: 87.91

GC content: 50.65

Gene sequence:

>306_bases
ATGGAATACATATACGCAGCAATGTTATTGCACACAACAGGTAAGGAAATCAACGAAGAAAACGTTAAAAGCGTCCTTGA
AGCAGCAGGCGCTGAAGTGGACGATGCAAGGGTCAAGGCTCTCATAGCAGCCCTTGAAGACGTTGATATCGAAGAGGCAA
TGGAAACAACAGCTGTAGCAGCAGCACCAGCAGCAGCTGCAGCACCAGCAGCAGCCGAAGAGGCTGAAGAAGAAGCTGAG
GAAGAAGAGGAAGAAGAGGAAGCTGAAGAGGAAGCAGCAGCCGGTCTCGGCGCACTCTTCGGTTAA

Upstream 100 bases:

>100_bases
GAGGAAGAAGAGGATGCAGCAGCCGGTCTCGGCGCACTCTTCGGATGAACACTTTACTGGCAATAGTTAACCCATAAAAA
ATAAAATTTGAGGTGATCAT

Downstream 100 bases:

>100_bases
ATCCCCCTTTATTTTTTTCCTCTGCCACTCTGTAATGGCAAAAAATTTATTTTTCTTAATTCTGATTCTATTTATAAAAA
CTGTTTTCAATGATTACCAT

Product: 50S ribosomal protein L12P

Products: NA

Alternate protein names: Ribosomal protein 'A'

Number of amino acids: Translated: 101; Mature: 101

Protein sequence:

>101_residues
MEYIYAAMLLHTTGKEINEENVKSVLEAAGAEVDDARVKALIAALEDVDIEEAMETTAVAAAPAAAAAPAAAEEAEEEAE
EEEEEEEAEEEAAAGLGALFG

Sequences:

>Translated_101_residues
MEYIYAAMLLHTTGKEINEENVKSVLEAAGAEVDDARVKALIAALEDVDIEEAMETTAVAAAPAAAAAPAAAEEAEEEAE
EEEEEEEAEEEAAAGLGALFG
>Mature_101_residues
MEYIYAAMLLHTTGKEINEENVKSVLEAAGAEVDDARVKALIAALEDVDIEEAMETTAVAAAPAAAAAPAAAEEAEEEAE
EEEEEEEAEEEAAAGLGALFG

Specific function: Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation

COG id: COG2058

COG function: function code J; Ribosomal protein L12E/L44/L45/RPP1/RPP2

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribosomal protein L12P family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RL12_METTH (P05394)

Other databases:

- EMBL:   AE000666
- PIR:   H69091
- RefSeq:   NP_276793.1
- STRING:   P05394
- GeneID:   1470767
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH1682
- NMPDR:   fig|187420.1.peg.1648
- eggNOG:   arNOG12589
- HOGENOM:   HBG726854
- OMA:   MEYIYGA
- ProtClustDB:   PRK06402
- BioCyc:   MTHE187420:MTH1682-MONOMER
- GO:   GO:0005840
- InterPro:   IPR001813
- InterPro:   IPR022295
- TIGRFAMs:   TIGR03685

Pfam domain/function: PF00428 Ribosomal_60s

EC number: NA

Molecular weight: Translated: 10480; Mature: 10480

Theoretical pI: Translated: 3.43; Mature: 3.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYIYAAMLLHTTGKEINEENVKSVLEAAGAEVDDARVKALIAALEDVDIEEAMETTAVA
CHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
AAPAAAAAPAAAEEAEEEAEEEEEEEEAEEEAAAGLGALFG
HCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEYIYAAMLLHTTGKEINEENVKSVLEAAGAEVDDARVKALIAALEDVDIEEAMETTAVA
CHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
AAPAAAAAPAAAEEAEEEAEEEEEEEEAEEEAAAGLGALFG
HCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463; 7006702