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The map label for this gene is rplP0

Identifier: 15679675

GI number: 15679675

Start: 1538659

End: 1539669

Strand: Direct

Name: rplP0

Synonym: MTH1681

Alternate gene names: 15679675

Gene position: 1538659-1539669 (Clockwise)

Preceding gene: 15679674

Following gene: 15679676

Centisome position: 87.85

GC content: 50.05

Gene sequence:

>1011_bases
ATGGCTCACGTGGCTGAATGGAAGAAGAAAGAGGTTCAGGAGCTCCATGACCTTATTAAAGGTTATGAAGTGGTTGGTAT
AGCCAACCTTGCAGACATACCTGCAAGGCAGCTCCAGAAGATGCGCCAGACACTCCGTGACAGTGCACTCATCAGAATGT
CCAAGAAGACCCTGATCAGCCTTGCCCTTGAGAAAGCTGGCAGAGAACTTGAAAATGTTGATTCACTCTCCGATTACATG
GAGGGGCAGCCTGCACTCATATTCACAGACATGAATCCCTTCAAGCTCTTCAAGATCCTTGAGGACAGTAAAACTCCTGC
TCCAGCCAAACCAGGGGCCATAGCCCCGGATGACATAGTTGTCCCCAAGGGGGATACCGGATTTGCACCGGGCCCGATAC
TGGGTGAACTGCAGCAGATAGGTATCCCTGCCAAGATCGAGAAGGGCAAGATTGTGGTTTCAAATGACCACGTCGTTGTG
AAGGCAGGGGAGGAGATTCCCCCCAAGGTGGCCGGGATATTAACCAGACTTGACATACAGCCACTTGAGGTGGGAATAGA
TCTCAGAGCAGCCTATGAAAATCAGACCGTCTACACTGCAGACGTACTGACCATCGATGAAGAGAAGACCCTGTCTGATA
TCCAGAAGGCATTTTCACAGGCATTCAACCTCTCAGTCAACGCTGTTATATACACCAGGGAGACAATGCCTGCTATCATC
CAGAAGGCAGCTTCAAAGTCATTCAACCTTGCATACAATGCATCAATACTCACATCAGAAACAACAGACCTCCTGCTTGC
AAAGGCCTATGCACAGATGCTTGCACTGGCCGCTGCAGCTGCGGAGATTAATGATGAGGCAGTTGATGATGAACTGAAGG
AGAAGCTGTCTTCAAGGGCAGCAGCACCAGCCCCTGAAGAAAAAGAGGAAGAGGTTGAAGAAGAAGCTGAAGAGGAAGAA
GAAGAGGAAGAAGAGGATGCAGCAGCCGGTCTCGGCGCACTCTTCGGATGA

Upstream 100 bases:

>100_bases
GGTTCTTCAGACAATCGACCGTAAACTTGAGAAGGGAAGAAACCAGTTAAAGTCCATGTACGTTAAGACAACCATGGGCC
CGGTAGTGAGGGTGATTTAA

Downstream 100 bases:

>100_bases
ACACTTTACTGGCAATAGTTAACCCATAAAAAATAAAATTTGAGGTGATCATATGGAATACATATACGCAGCAATGTTAT
TGCACACAACAGGTAAGGAA

Product: acidic ribosomal protein P0

Products: NA

Alternate protein names: L10E

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MAHVAEWKKKEVQELHDLIKGYEVVGIANLADIPARQLQKMRQTLRDSALIRMSKKTLISLALEKAGRELENVDSLSDYM
EGQPALIFTDMNPFKLFKILEDSKTPAPAKPGAIAPDDIVVPKGDTGFAPGPILGELQQIGIPAKIEKGKIVVSNDHVVV
KAGEEIPPKVAGILTRLDIQPLEVGIDLRAAYENQTVYTADVLTIDEEKTLSDIQKAFSQAFNLSVNAVIYTRETMPAII
QKAASKSFNLAYNASILTSETTDLLLAKAYAQMLALAAAAAEINDEAVDDELKEKLSSRAAAPAPEEKEEEVEEEAEEEE
EEEEEDAAAGLGALFG

Sequences:

>Translated_336_residues
MAHVAEWKKKEVQELHDLIKGYEVVGIANLADIPARQLQKMRQTLRDSALIRMSKKTLISLALEKAGRELENVDSLSDYM
EGQPALIFTDMNPFKLFKILEDSKTPAPAKPGAIAPDDIVVPKGDTGFAPGPILGELQQIGIPAKIEKGKIVVSNDHVVV
KAGEEIPPKVAGILTRLDIQPLEVGIDLRAAYENQTVYTADVLTIDEEKTLSDIQKAFSQAFNLSVNAVIYTRETMPAII
QKAASKSFNLAYNASILTSETTDLLLAKAYAQMLALAAAAAEINDEAVDDELKEKLSSRAAAPAPEEKEEEVEEEAEEEE
EEEEEDAAAGLGALFG
>Mature_335_residues
AHVAEWKKKEVQELHDLIKGYEVVGIANLADIPARQLQKMRQTLRDSALIRMSKKTLISLALEKAGRELENVDSLSDYME
GQPALIFTDMNPFKLFKILEDSKTPAPAKPGAIAPDDIVVPKGDTGFAPGPILGELQQIGIPAKIEKGKIVVSNDHVVVK
AGEEIPPKVAGILTRLDIQPLEVGIDLRAAYENQTVYTADVLTIDEEKTLSDIQKAFSQAFNLSVNAVIYTRETMPAIIQ
KAASKSFNLAYNASILTSETTDLLLAKAYAQMLALAAAAAEINDEAVDDELKEKLSSRAAAPAPEEKEEEVEEEAEEEEE
EEEEDAAAGLGALFG

Specific function: Ribosomal protein P0 is the functional equivalent of E.coli protein L10

COG id: COG0244

COG function: function code J; Ribosomal protein L10

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribosomal protein L10P family

Homologues:

Organism=Homo sapiens, GI4506667, Length=207, Percent_Identity=29.4685990338164, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI16933546, Length=207, Percent_Identity=29.4685990338164, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17506815, Length=229, Percent_Identity=30.1310043668122, Blast_Score=99, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6323371, Length=239, Percent_Identity=27.1966527196653, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17737731, Length=220, Percent_Identity=29.5454545454545, Blast_Score=102, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RLA0_METTH (O27717)

Other databases:

- EMBL:   AE000666
- PIR:   G69091
- RefSeq:   NP_276792.1
- ProteinModelPortal:   O27717
- STRING:   O27717
- GeneID:   1470766
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH1681
- NMPDR:   fig|187420.1.peg.1647
- eggNOG:   arNOG04753
- HOGENOM:   HBG731512
- OMA:   KGPTSFK
- PhylomeDB:   O27717
- ProtClustDB:   PRK04019
- BioCyc:   MTHE187420:MTH1681-MONOMER
- GO:   GO:0005840
- GO:   GO:0006412
- HAMAP:   MF_00280
- InterPro:   IPR001790
- InterPro:   IPR013522
- InterPro:   IPR022909
- Gene3D:   G3DSA:1.10.10.380

Pfam domain/function: PF00466 Ribosomal_L10

EC number: NA

Molecular weight: Translated: 36511; Mature: 36380

Theoretical pI: Translated: 4.26; Mature: 4.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHVAEWKKKEVQELHDLIKGYEVVGIANLADIPARQLQKMRQTLRDSALIRMSKKTLIS
CCCHHHHHHHHHHHHHHHHCCCEEEEECCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LALEKAGRELENVDSLSDYMEGQPALIFTDMNPFKLFKILEDSKTPAPAKPGAIAPDDIV
HHHHHHCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCEE
VPKGDTGFAPGPILGELQQIGIPAKIEKGKIVVSNDHVVVKAGEEIPPKVAGILTRLDIQ
ECCCCCCCCCCCHHHHHHHCCCCCEECCCEEEEECCEEEEECCCCCCHHHHHHHHHCCCC
PLEVGIDLRAAYENQTVYTADVLTIDEEKTLSDIQKAFSQAFNLSVNAVIYTRETMPAII
HHHCCEEEEEECCCCEEEEEEEEEECCHHHHHHHHHHHHHHHCCEEEEEEEECHHHHHHH
QKAASKSFNLAYNASILTSETTDLLLAKAYAQMLALAAAAAEINDEAVDDELKEKLSSRA
HHHHCCCCCEEECCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
AAPAPEEKEEEVEEEAEEEEEEEEEDAAAGLGALFG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AHVAEWKKKEVQELHDLIKGYEVVGIANLADIPARQLQKMRQTLRDSALIRMSKKTLIS
CCHHHHHHHHHHHHHHHHCCCEEEEECCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LALEKAGRELENVDSLSDYMEGQPALIFTDMNPFKLFKILEDSKTPAPAKPGAIAPDDIV
HHHHHHCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCEE
VPKGDTGFAPGPILGELQQIGIPAKIEKGKIVVSNDHVVVKAGEEIPPKVAGILTRLDIQ
ECCCCCCCCCCCHHHHHHHCCCCCEECCCEEEEECCEEEEECCCCCCHHHHHHHHHCCCC
PLEVGIDLRAAYENQTVYTADVLTIDEEKTLSDIQKAFSQAFNLSVNAVIYTRETMPAII
HHHCCEEEEEECCCCEEEEEEEEEECCHHHHHHHHHHHHHHHCCEEEEEEEECHHHHHHH
QKAASKSFNLAYNASILTSETTDLLLAKAYAQMLALAAAAAEINDEAVDDELKEKLSSRA
HHHHCCCCCEEECCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
AAPAPEEKEEEVEEEAEEEEEEEEEDAAAGLGALFG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463