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Identifier: 15679670

GI number: 15679670

Start: 1535479

End: 1536624

Strand: Direct

Name: Not Available

Synonym: MTH1676

Alternate gene names: 15679670

Gene position: 1535479-1536624 (Clockwise)

Preceding gene: 15679669

Following gene: 15679671

Centisome position: 87.67

GC content: 51.13

Gene sequence:

>1146_bases
TTGAAATTCATTAACGATGCCATAAAGGAATCTGAGAAAAGGGAAAAGCCATCTTCCAGCTCAATGAATTCAGAAATTGA
CAGGGAACTCCGGGAAATAATTGAAAATAGCAGAGCCAAGATATACGTTGTTGGGACCGGCGGGGCGGGCAACAACACCG
TAACAAGGCTCAGTGAGATTGGAGTAGAGGGCGCTGAGACCATAGCCGTTAACACAGATGCCCAGGACCTCTTTTACTCC
GTGGCTAACCGGAAGCTTCTCATAGGTAAGAATGTCTGTGGTGGTCTTGGAGCTGGCGGCGTCCCTGAAGTGGGAGAGGA
ATGCGCAGAGGAAAGTGAGGATGATATTCGCAGGGAACTCGAAGGGGCTGACATGGTCTTTGTAACCTGTGGCCTTGGGG
GTGGCACGGGAACAGGGTCCGCACCTGTGATATCAAAACTTGCCAAAAAGGCGGGTGCCCTCACGATAGCCGTTGCAACC
ATGCCCTTCAGTGCAGAGGGCCTTAAAAGGAGGGAGAATGCTGAGAGGGGTCTTGAGAAACTCCAGAGCGCTGCAGATAC
AGTCATTGTCATACCCAATGACAAGCTACTGGAGGTTGCACCCAACCTGCCCCTCAACAAGGCCTTCATGGTTGCAGACG
AGATCCTTGGAAGGGCGGTTAAGGGTATAACTGAACTCATAACCAAACCCGGACTGGTGAGCCTCGACTTTGCGGATGTG
AGGAGCATAATGAAGGGTTCAGGAATGGCCATGATTGGAATGGGCGAGGCCGAATCCGGTGACAGGGCCCTAGAATCAGT
TTATGAGGCCCTTAACAGTCCGCTGCTGGATCTTGACATATCCAATGCAAGGGGAGCCCTTATAAACATATCTGGTAGTT
CAGACCTGACCCTCCAGGAGGCCGAAAGGATCGTGGAGGTTGTTGCCGAGGAACTTGATCCCGATGCAAACATAATATGG
GGTGCCCAGATTCAGGATGAACTGCAGAACGTCATAAGAACGACCATCGTTGTTGCGGGTGTAAGGTCACCCTACATCTA
TGGGGCCCATGGCTCTGCAGAGAAGGAGTTCCTGGAGGAAAAACAGCGTGAAAAGGACTCAGTCGATGAGTCCGTCCTGG
AAGAATTTATAGATGGAGTATTCTGA

Upstream 100 bases:

>100_bases
TTGAATGTGAGCCATGGCTCCATCGGTGCCAGATTAACCGTTGCTTTTAAATATGTCTTATCACAATAACATATTTCATA
GATAAGTGTGGGGGTAGTAA

Downstream 100 bases:

>100_bases
TATTCTTCCACACACCCCCACTCAAGGAAAACCTTTATAAATCTTGAAGGATAGATTACTCCATCACTCATCCCAATCCT
AGCCCTTGTTTTTTAACTAT

Product: cell division protein FtsZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MKFINDAIKESEKREKPSSSSMNSEIDRELREIIENSRAKIYVVGTGGAGNNTVTRLSEIGVEGAETIAVNTDAQDLFYS
VANRKLLIGKNVCGGLGAGGVPEVGEECAEESEDDIRRELEGADMVFVTCGLGGGTGTGSAPVISKLAKKAGALTIAVAT
MPFSAEGLKRRENAERGLEKLQSAADTVIVIPNDKLLEVAPNLPLNKAFMVADEILGRAVKGITELITKPGLVSLDFADV
RSIMKGSGMAMIGMGEAESGDRALESVYEALNSPLLDLDISNARGALINISGSSDLTLQEAERIVEVVAEELDPDANIIW
GAQIQDELQNVIRTTIVVAGVRSPYIYGAHGSAEKEFLEEKQREKDSVDESVLEEFIDGVF

Sequences:

>Translated_381_residues
MKFINDAIKESEKREKPSSSSMNSEIDRELREIIENSRAKIYVVGTGGAGNNTVTRLSEIGVEGAETIAVNTDAQDLFYS
VANRKLLIGKNVCGGLGAGGVPEVGEECAEESEDDIRRELEGADMVFVTCGLGGGTGTGSAPVISKLAKKAGALTIAVAT
MPFSAEGLKRRENAERGLEKLQSAADTVIVIPNDKLLEVAPNLPLNKAFMVADEILGRAVKGITELITKPGLVSLDFADV
RSIMKGSGMAMIGMGEAESGDRALESVYEALNSPLLDLDISNARGALINISGSSDLTLQEAERIVEVVAEELDPDANIIW
GAQIQDELQNVIRTTIVVAGVRSPYIYGAHGSAEKEFLEEKQREKDSVDESVLEEFIDGVF
>Mature_381_residues
MKFINDAIKESEKREKPSSSSMNSEIDRELREIIENSRAKIYVVGTGGAGNNTVTRLSEIGVEGAETIAVNTDAQDLFYS
VANRKLLIGKNVCGGLGAGGVPEVGEECAEESEDDIRRELEGADMVFVTCGLGGGTGTGSAPVISKLAKKAGALTIAVAT
MPFSAEGLKRRENAERGLEKLQSAADTVIVIPNDKLLEVAPNLPLNKAFMVADEILGRAVKGITELITKPGLVSLDFADV
RSIMKGSGMAMIGMGEAESGDRALESVYEALNSPLLDLDISNARGALINISGSSDLTLQEAERIVEVVAEELDPDANIIW
GAQIQDELQNVIRTTIVVAGVRSPYIYGAHGSAEKEFLEEKQREKDSVDESVLEEFIDGVF

Specific function: This protein is essential to the cell-division process. It seems to assemble into a dynamic ring on the inner surface of the cytoplasmic membrane at the place where division will occur, and the formation of the ring is the signal for septation to begin. B

COG id: COG0206

COG function: function code D; Cell division GTPase

Gene ontology:

Cell location: Cytoplasm. Assemble at the Inner Surface of the Cytoplasmic Membrane. [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsZ family

Homologues:

Organism=Escherichia coli, GI1786284, Length=292, Percent_Identity=45.5479452054795, Blast_Score=218, Evalue=5e-58,

Paralogues:

None

Copy number: 320 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): FTSZ_METTH (O27712)

Other databases:

- EMBL:   AE000666
- PIR:   A69091
- RefSeq:   NP_276787.1
- ProteinModelPortal:   O27712
- SMR:   O27712
- STRING:   O27712
- GeneID:   1470761
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH1676
- NMPDR:   fig|187420.1.peg.1642
- eggNOG:   arNOG04751
- HOGENOM:   HBG478075
- OMA:   NANLIFG
- ProtClustDB:   PRK09330
- BioCyc:   MTHE187420:MTH1676-MONOMER
- GO:   GO:0005737
- InterPro:   IPR020805
- InterPro:   IPR000158
- InterPro:   IPR008280
- InterPro:   IPR018316
- InterPro:   IPR003008
- Gene3D:   G3DSA:3.30.1330.20
- Gene3D:   G3DSA:3.40.50.1440
- PRINTS:   PR00423
- SMART:   SM00864
- SMART:   SM00865
- TIGRFAMs:   TIGR00065

Pfam domain/function: PF00091 Tubulin; SSF55307 Tub_FtsZ_C; SSF52490 Tubulin_FtsZ

EC number: 3.4.24.-

Molecular weight: Translated: 40619; Mature: 40619

Theoretical pI: Translated: 4.24; Mature: 4.24

Prosite motif: PS01134 FTSZ_1; PS01135 FTSZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFINDAIKESEKREKPSSSSMNSEIDRELREIIENSRAKIYVVGTGGAGNNTVTRLSEI
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHH
GVEGAETIAVNTDAQDLFYSVANRKLLIGKNVCGGLGAGGVPEVGEECAEESEDDIRREL
CCCCCCEEEECCCHHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHCCHHHHHHHH
EGADMVFVTCGLGGGTGTGSAPVISKLAKKAGALTIAVATMPFSAEGLKRRENAERGLEK
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHH
LQSAADTVIVIPNDKLLEVAPNLPLNKAFMVADEILGRAVKGITELITKPGLVSLDFADV
HHHHCCEEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHH
RSIMKGSGMAMIGMGEAESGDRALESVYEALNSPLLDLDISNARGALINISGSSDLTLQE
HHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCCCCCCHHH
AERIVEVVAEELDPDANIIWGAQIQDELQNVIRTTIVVAGVRSPYIYGAHGSAEKEFLEE
HHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHEECCCCEEECCCCCHHHHHHHH
KQREKDSVDESVLEEFIDGVF
HHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKFINDAIKESEKREKPSSSSMNSEIDRELREIIENSRAKIYVVGTGGAGNNTVTRLSEI
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHH
GVEGAETIAVNTDAQDLFYSVANRKLLIGKNVCGGLGAGGVPEVGEECAEESEDDIRREL
CCCCCCEEEECCCHHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHCCHHHHHHHH
EGADMVFVTCGLGGGTGTGSAPVISKLAKKAGALTIAVATMPFSAEGLKRRENAERGLEK
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHH
LQSAADTVIVIPNDKLLEVAPNLPLNKAFMVADEILGRAVKGITELITKPGLVSLDFADV
HHHHCCEEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHH
RSIMKGSGMAMIGMGEAESGDRALESVYEALNSPLLDLDISNARGALINISGSSDLTLQE
HHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCCCCCCHHH
AERIVEVVAEELDPDANIIWGAQIQDELQNVIRTTIVVAGVRSPYIYGAHGSAEKEFLEE
HHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHEECCCCEEECCCCCHHHHHHHH
KQREKDSVDESVLEEFIDGVF
HHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9371463