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Identifier: 15679653

GI number: 15679653

Start: 1521786

End: 1522511

Strand: Direct

Name: Not Available

Synonym: MTH1658

Alternate gene names: 15679653

Gene position: 1521786-1522511 (Clockwise)

Preceding gene: 15679652

Following gene: 15679654

Centisome position: 86.89

GC content: 52.89

Gene sequence:

>726_bases
TTGAACAGTTCGCATGAGTCCCTGGCAGATGTACTCGTAAAGATCTGCGGTATAAAAAGGCCAGAGGACGCAATACTGGC
AGATAAACTTGGTGCTGACCTCCTTGGCCTCATACACGTAGAGAGATCACCACGACACCTCACAGGAAGGGAACTGGAGG
ACATCCTATCACTCATACCTCCTGAGAAGGCCGTGATCGTCCTTGAACCCTCCGATCCAGTGGAGGTGGCTGAGGTTATT
GAGAGAACAGGTGTGGAGAGAGTCCAGCTCCACTCCATCTCATGTGAAGATGCCAGGGGCATAAAGAGGGTACTCACTGA
AAACGGGTTTAATCCAGGGATAACAGTCGCAGTACCACCGGAGCCCGGTTCACTGGATGTTCTTGACCACATCCCATGTT
CATGTGTCATGCTCGATTCCAGCTCCGGTGGTAGAACAGGGGGGACGGGGAGGATGATTCCACCCGAACTGGCCCTCGGG
ATGCTCCGCCTCATAAGAAGTCATGAGAGCGCACCGGAGGTGGCCCTTGCAGGGGGCCTTGGACCATCCACTGTGAGGCT
TAACCCTGAATACTTACTGGAATTCGATTGTCTGGACTTCAACTCTGGCATTGAGGCTGCACCGGGGATAAAGGATCATG
CAATGATGTTTGAACTCATGGAGTACATGGGGAGGACGGGCGGACTTCAGAAACCGTCCAGGTTACAGAGAGGTGAGTTA
TCATGA

Upstream 100 bases:

>100_bases
CCCATGTCAGCCCAGAACCCACGGGAACTCCTTGAGGAGATAGTAGATGCGGTGAGCCAGTGCAGGGACCGGAGAAGAAG
GTACACGGGGGATGAATTCT

Downstream 100 bases:

>100_bases
TAATGGATGGAAAATTCGGTAAATATGGAGGCATATTCGTGCCGGAGCTTCTTATACCGGCACTTGAGGAACTTGAGAGG
GCCTTCCTCCATTACAGGGA

Product: 5'-phosphoribosyl anthranilate isomerase

Products: NA

Alternate protein names: PRAI

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MNSSHESLADVLVKICGIKRPEDAILADKLGADLLGLIHVERSPRHLTGRELEDILSLIPPEKAVIVLEPSDPVEVAEVI
ERTGVERVQLHSISCEDARGIKRVLTENGFNPGITVAVPPEPGSLDVLDHIPCSCVMLDSSSGGRTGGTGRMIPPELALG
MLRLIRSHESAPEVALAGGLGPSTVRLNPEYLLEFDCLDFNSGIEAAPGIKDHAMMFELMEYMGRTGGLQKPSRLQRGEL
S

Sequences:

>Translated_241_residues
MNSSHESLADVLVKICGIKRPEDAILADKLGADLLGLIHVERSPRHLTGRELEDILSLIPPEKAVIVLEPSDPVEVAEVI
ERTGVERVQLHSISCEDARGIKRVLTENGFNPGITVAVPPEPGSLDVLDHIPCSCVMLDSSSGGRTGGTGRMIPPELALG
MLRLIRSHESAPEVALAGGLGPSTVRLNPEYLLEFDCLDFNSGIEAAPGIKDHAMMFELMEYMGRTGGLQKPSRLQRGEL
S
>Mature_241_residues
MNSSHESLADVLVKICGIKRPEDAILADKLGADLLGLIHVERSPRHLTGRELEDILSLIPPEKAVIVLEPSDPVEVAEVI
ERTGVERVQLHSISCEDARGIKRVLTENGFNPGITVAVPPEPGSLDVLDHIPCSCVMLDSSSGGRTGGTGRMIPPELALG
MLRLIRSHESAPEVALAGGLGPSTVRLNPEYLLEFDCLDFNSGIEAAPGIKDHAMMFELMEYMGRTGGLQKPSRLQRGEL
S

Specific function: Unknown

COG id: COG0135

COG function: function code E; Phosphoribosylanthranilate isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpF family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TRPF_METTH (O27695)

Other databases:

- EMBL:   AE000666
- PIR:   F69088
- RefSeq:   NP_276770.1
- ProteinModelPortal:   O27695
- SMR:   O27695
- STRING:   O27695
- GeneID:   1470743
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH1658
- NMPDR:   fig|187420.1.peg.1625
- eggNOG:   arNOG13143
- HOGENOM:   HBG554803
- OMA:   IRSHESA
- ProtClustDB:   CLSK342505
- BioCyc:   MTHE187420:MTH1658-MONOMER
- BRENDA:   5.3.1.24
- HAMAP:   MF_00135_A
- InterPro:   IPR013785
- InterPro:   IPR001240
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70

Pfam domain/function: PF00697 PRAI; SSF51366 RibP_bind_barrel

EC number: =5.3.1.24

Molecular weight: Translated: 25926; Mature: 25926

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSSHESLADVLVKICGIKRPEDAILADKLGADLLGLIHVERSPRHLTGRELEDILSLIP
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCHHHEEHEEECCCCCCCCHHHHHHHHHHCC
PEKAVIVLEPSDPVEVAEVIERTGVERVQLHSISCEDARGIKRVLTENGFNPGITVAVPP
CCCEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEECC
EPGSLDVLDHIPCSCVMLDSSSGGRTGGTGRMIPPELALGMLRLIRSHESAPEVALAGGL
CCCCCCHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCC
GPSTVRLNPEYLLEFDCLDFNSGIEAAPGIKDHAMMFELMEYMGRTGGLQKPSRLQRGEL
CCCEEEECHHHEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHCCCCCC
S
C
>Mature Secondary Structure
MNSSHESLADVLVKICGIKRPEDAILADKLGADLLGLIHVERSPRHLTGRELEDILSLIP
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCHHHEEHEEECCCCCCCCHHHHHHHHHHCC
PEKAVIVLEPSDPVEVAEVIERTGVERVQLHSISCEDARGIKRVLTENGFNPGITVAVPP
CCCEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEECC
EPGSLDVLDHIPCSCVMLDSSSGGRTGGTGRMIPPELALGMLRLIRSHESAPEVALAGGL
CCCCCCHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCC
GPSTVRLNPEYLLEFDCLDFNSGIEAAPGIKDHAMMFELMEYMGRTGGLQKPSRLQRGEL
CCCEEEECHHHEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHCCCCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463