Click here to switch to the map view.

The map label for this gene is Not Available

Identifier: 15679579

GI number: 15679579

Start: 1450455

End: 1451822

Strand: Direct

Name: Not Available

Synonym: MTH1584

Alternate gene names: 15679579

Gene position: 1450455-1451822 (Clockwise)

Preceding gene: 15679578

Following gene: 15679596

Centisome position: 82.82

GC content: 50.07

Gene sequence:

>1368_bases
ATGAAGAAACTATTTGGCACATTCGGAGTTAGAAGACTTGCAAATGAGGTTTTAACACCTGAATTCGCATCAAAGCTTGC
GGCAGCATACGGTTCAACTGTAGAAGGGAAAATAGCTGTTGGAGGAGATACAAGGACATCCACTGTAATGATAAAGAATG
CTGTCATATCCGGCCTTCTTTCAAGCGGATGTGATGTTGTTGACCTGGGAATACTCCCAACGCCAGCCGTTCAGTATGCA
GTCAGAAAATATTATGATGGAGGGGTTATCGTAACGGCGTCCCACAACCCCCCACAGTACAACGGTATAAAATTCGTTGA
CTCAGACGGCATAGGCATCCCTGATGACCTGGAGGAGGAAATAGAAAGGATATTCTTCAGCGAAGATTTCAGGAGGGCCT
CCTGGGATAAAATCGGAAACCTCACATCAAACCCCTCCATAATCAGGGAGTACCAGGACGGTGTCATAGCGAGGGTCGAT
GCAGAGGCCATCCGTAGAAGGAAATTCCGGGTGGTGGTCGACTGTGGCTGTGGAGCAGCGTCCTACACCATGCCCTACAT
CCTCAGGAGGCTCGGATGTCAGGTGATAGCACTTAACTCTCAGCCTGATGGTTTCTTCCCGGGCCGTGACCCTGAACCTG
TCCCTGAGAACCTCTCGGAGCTGATGGAGACTGTGAGGTCAACCGGGGCTGATCTGGGCATAGCCCACGACGGTGACGCA
GACAGGACAATATGTATCGATGAGAGGGGAGAATTTGTCCTCGGCGATAAGACATTCGCCCTTGTTGAGAAGAGGATGCT
CCAGGAAAAGGGTGGAGGCATAATAGTCACCACCGTCGCAACATCCTCAGCAATATACGATATAGCATCAGAGAACAACG
GAGAGGTAATAACAACAGCTGTAGGGGACCTCCTGGTGGCAAGAAAACTTAAAGAGACAGACGGACTATTTGGAGGCGAG
GAAAACGGTGGATTAATATTCCCCGACTTTGTATACGGGAGGGACGCAGCCCTCACAGCCGCCACGATACTCGAGATAAT
GGCCCATGAGGACAGGCCACTATCAGCGCTTGTATCGGAACTACCCGCATATTACTCCAGTAAGAGGAAAATAGAATGTC
CCGATGAAATTAAAGGGGATGTGATGGACCTGGTAAGTAAGATGCTGGCAGATGAGGAGGGTGTAAGGGACATAGATACC
ACAGACGGTGTTAAAATATTCAGTGAAGCCGGGTGGGTCATAATAAGGCCCTCAGGGACCGAGCCAATATTCAGATGCTT
CGCAGAGTCAGAGACACAGGAGCAGGCAGATGAAATGGCCCGCTGGGGCATATCCCTGGTCGAGAGGGCCATGGAAAAAC
TGAAATAG

Upstream 100 bases:

>100_bases
AGGTAATGTGATTAAAAATTCATACGGAGTGAAGGTCTGACTTTATCCATATTGGTGATTAACAATTCAAATATTATCCA
GTGAATGGGGCTGTTAAAAA

Downstream 100 bases:

>100_bases
CTGTTTAGAGGTTCTCAAGGCACTCCTCACGGAGTATCCCGGCATCCTCATTTTTCGGGTTTATCATCAGGGCCCTGTTG
AAGGCCTCAAGGGCCTCATC

Product: phosphomannomutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MKKLFGTFGVRRLANEVLTPEFASKLAAAYGSTVEGKIAVGGDTRTSTVMIKNAVISGLLSSGCDVVDLGILPTPAVQYA
VRKYYDGGVIVTASHNPPQYNGIKFVDSDGIGIPDDLEEEIERIFFSEDFRRASWDKIGNLTSNPSIIREYQDGVIARVD
AEAIRRRKFRVVVDCGCGAASYTMPYILRRLGCQVIALNSQPDGFFPGRDPEPVPENLSELMETVRSTGADLGIAHDGDA
DRTICIDERGEFVLGDKTFALVEKRMLQEKGGGIIVTTVATSSAIYDIASENNGEVITTAVGDLLVARKLKETDGLFGGE
ENGGLIFPDFVYGRDAALTAATILEIMAHEDRPLSALVSELPAYYSSKRKIECPDEIKGDVMDLVSKMLADEEGVRDIDT
TDGVKIFSEAGWVIIRPSGTEPIFRCFAESETQEQADEMARWGISLVERAMEKLK

Sequences:

>Translated_455_residues
MKKLFGTFGVRRLANEVLTPEFASKLAAAYGSTVEGKIAVGGDTRTSTVMIKNAVISGLLSSGCDVVDLGILPTPAVQYA
VRKYYDGGVIVTASHNPPQYNGIKFVDSDGIGIPDDLEEEIERIFFSEDFRRASWDKIGNLTSNPSIIREYQDGVIARVD
AEAIRRRKFRVVVDCGCGAASYTMPYILRRLGCQVIALNSQPDGFFPGRDPEPVPENLSELMETVRSTGADLGIAHDGDA
DRTICIDERGEFVLGDKTFALVEKRMLQEKGGGIIVTTVATSSAIYDIASENNGEVITTAVGDLLVARKLKETDGLFGGE
ENGGLIFPDFVYGRDAALTAATILEIMAHEDRPLSALVSELPAYYSSKRKIECPDEIKGDVMDLVSKMLADEEGVRDIDT
TDGVKIFSEAGWVIIRPSGTEPIFRCFAESETQEQADEMARWGISLVERAMEKLK
>Mature_455_residues
MKKLFGTFGVRRLANEVLTPEFASKLAAAYGSTVEGKIAVGGDTRTSTVMIKNAVISGLLSSGCDVVDLGILPTPAVQYA
VRKYYDGGVIVTASHNPPQYNGIKFVDSDGIGIPDDLEEEIERIFFSEDFRRASWDKIGNLTSNPSIIREYQDGVIARVD
AEAIRRRKFRVVVDCGCGAASYTMPYILRRLGCQVIALNSQPDGFFPGRDPEPVPENLSELMETVRSTGADLGIAHDGDA
DRTICIDERGEFVLGDKTFALVEKRMLQEKGGGIIVTTVATSSAIYDIASENNGEVITTAVGDLLVARKLKETDGLFGGE
ENGGLIFPDFVYGRDAALTAATILEIMAHEDRPLSALVSELPAYYSSKRKIECPDEIKGDVMDLVSKMLADEEGVRDIDT
TDGVKIFSEAGWVIIRPSGTEPIFRCFAESETQEQADEMARWGISLVERAMEKLK

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1788361, Length=442, Percent_Identity=28.7330316742081, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1789566, Length=450, Percent_Identity=30.8888888888889, Blast_Score=158, Evalue=8e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.10 [H]

Molecular weight: Translated: 49580; Mature: 49580

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLFGTFGVRRLANEVLTPEFASKLAAAYGSTVEGKIAVGGDTRTSTVMIKNAVISGLL
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEHHHHHHHHHH
SSGCDVVDLGILPTPAVQYAVRKYYDGGVIVTASHNPPQYNGIKFVDSDGIGIPDDLEEE
HCCCCEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEECCCCCCCCHHHHHH
IERIFFSEDFRRASWDKIGNLTSNPSIIREYQDGVIARVDAEAIRRRKFRVVVDCGCGAA
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCEEEEECHHHHHCCCEEEEEECCCCCH
SYTMPYILRRLGCQVIALNSQPDGFFPGRDPEPVPENLSELMETVRSTGADLGIAHDGDA
HHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
DRTICIDERGEFVLGDKTFALVEKRMLQEKGGGIIVTTVATSSAIYDIASENNGEVITTA
CCEEEEECCCCEEECCHHHHHHHHHHHHHCCCCEEEEEEECCCHHEEECCCCCCCEEEEH
VGDLLVARKLKETDGLFGGEENGGLIFPDFVYGRDAALTAATILEIMAHEDRPLSALVSE
HHHHHHHHHHHHHCCCCCCCCCCCEECCCHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHH
LPAYYSSKRKIECPDEIKGDVMDLVSKMLADEEGVRDIDTTDGVKIFSEAGWVIIRPSGT
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCEEEEECCCC
EPIFRCFAESETQEQADEMARWGISLVERAMEKLK
CHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKLFGTFGVRRLANEVLTPEFASKLAAAYGSTVEGKIAVGGDTRTSTVMIKNAVISGLL
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEHHHHHHHHHH
SSGCDVVDLGILPTPAVQYAVRKYYDGGVIVTASHNPPQYNGIKFVDSDGIGIPDDLEEE
HCCCCEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEECCCCCCCCHHHHHH
IERIFFSEDFRRASWDKIGNLTSNPSIIREYQDGVIARVDAEAIRRRKFRVVVDCGCGAA
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCEEEEECHHHHHCCCEEEEEECCCCCH
SYTMPYILRRLGCQVIALNSQPDGFFPGRDPEPVPENLSELMETVRSTGADLGIAHDGDA
HHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
DRTICIDERGEFVLGDKTFALVEKRMLQEKGGGIIVTTVATSSAIYDIASENNGEVITTA
CCEEEEECCCCEEECCHHHHHHHHHHHHHCCCCEEEEEEECCCHHEEECCCCCCCEEEEH
VGDLLVARKLKETDGLFGGEENGGLIFPDFVYGRDAALTAATILEIMAHEDRPLSALVSE
HHHHHHHHHHHHHCCCCCCCCCCCEECCCHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHH
LPAYYSSKRKIECPDEIKGDVMDLVSKMLADEEGVRDIDTTDGVKIFSEAGWVIIRPSGT
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCEEEEECCCC
EPIFRCFAESETQEQADEMARWGISLVERAMEKLK
CHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]