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Identifier: 15679286

GI number: 15679286

Start: 1163891

End: 1164700

Strand: Direct

Name: Not Available

Synonym: MTH1282

Alternate gene names: NA

Gene position: 1163891-1164700 (Clockwise)

Preceding gene: 15679285

Following gene: 15679287

Centisome position: 66.46

GC content: 47.78

Gene sequence:

>810_bases
ATGAGCAACAAGGCACTTGTAAGGGACTACATGACCCGGGACGTTATAACGGTATCCTCAGATACTTCAACTGCTGAGAT
AATCAAACTTATGAAGGAAACAGGGCACGATGGGTTCCCTGTTAAGGATAACGGTTCTGTGATCGGGATGGTGACGGCCT
TTGACCTTCTGATAAAACCGTGGGTTAAAACCGTCTCAGAGATCATGTCAAGGGATGTTGTTGTGGCTGACCAGGACATG
TCACTCAATGACGCCGCAAGGGTGATGTTCAGGATGGGCATCTCCAGACTACCTGTTATAAACAAGGAGGGTAAGCTTGT
TGGAATCATAACAAACACCGATATCGTGAGGTCCCACATCGAGCGTTCAACACCCATGAAGGTCAACTACTTCAAGAAGA
CCCTGGAACAGCTCTATGGTGTTAAACCAGAGGTTAAAAGGATGAAGGTCCCAATCGAGAAATTGAGGCCAACCCAGAAC
AAGGTCTATGCCGATGAACTCCAGGGCAGGACCTATGAAATTAAAAGGGGTCTTGCAGAGCCCACAATAGTTGTTAAGAC
AGGTGAAAGGTACGTCCTCATTGATGGTCACCACAGGACCCTCGCATCCTACAGGCTCGGGTGCAAGGAGATAGACTCCT
ATGTCATAGATATAAAGAAGGATATGAAGCTGGGTATGGAGAAGACAGCTGACCTCAATGGTGTTCACACCCTGGAGGAC
ATAGAGGTCATAGATGACGCCCAGCACCCACTGATTGCGATAACGACGAGCATGAGAAAGGCCATGGCAGGTAAGAAGAA
TGGTAGATGA

Upstream 100 bases:

>100_bases
TCATGATACTGAGGGATGGGAGCTCCATCCCATACCACCGTGTGGTGAAGATAGTCTGTGATAACAGTTTCATCTGGAAA
AAACAGAAGAAGGGAATAGG

Downstream 100 bases:

>100_bases
GGGAATTTTAAGGGAAGTATACCGTGTGCTTGAGGATCGGAGGGACAGACCCATTGATTCATACACTTCACGCCTCATGA
GGGATGATGATAAAATGGCA

Product: inosine-5'-monophosphate dehydrogenase related protein VI

Products: xanthosine 5'-phosphate; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MSNKALVRDYMTRDVITVSSDTSTAEIIKLMKETGHDGFPVKDNGSVIGMVTAFDLLIKPWVKTVSEIMSRDVVVADQDM
SLNDAARVMFRMGISRLPVINKEGKLVGIITNTDIVRSHIERSTPMKVNYFKKTLEQLYGVKPEVKRMKVPIEKLRPTQN
KVYADELQGRTYEIKRGLAEPTIVVKTGERYVLIDGHHRTLASYRLGCKEIDSYVIDIKKDMKLGMEKTADLNGVHTLED
IEVIDDAQHPLIAITTSMRKAMAGKKNGR

Sequences:

>Translated_269_residues
MSNKALVRDYMTRDVITVSSDTSTAEIIKLMKETGHDGFPVKDNGSVIGMVTAFDLLIKPWVKTVSEIMSRDVVVADQDM
SLNDAARVMFRMGISRLPVINKEGKLVGIITNTDIVRSHIERSTPMKVNYFKKTLEQLYGVKPEVKRMKVPIEKLRPTQN
KVYADELQGRTYEIKRGLAEPTIVVKTGERYVLIDGHHRTLASYRLGCKEIDSYVIDIKKDMKLGMEKTADLNGVHTLED
IEVIDDAQHPLIAITTSMRKAMAGKKNGR
>Mature_268_residues
SNKALVRDYMTRDVITVSSDTSTAEIIKLMKETGHDGFPVKDNGSVIGMVTAFDLLIKPWVKTVSEIMSRDVVVADQDMS
LNDAARVMFRMGISRLPVINKEGKLVGIITNTDIVRSHIERSTPMKVNYFKKTLEQLYGVKPEVKRMKVPIEKLRPTQNK
VYADELQGRTYEIKRGLAEPTIVVKTGERYVLIDGHHRTLASYRLGCKEIDSYVIDIKKDMKLGMEKTADLNGVHTLEDI
EVIDDAQHPLIAITTSMRKAMAGKKNGR

Specific function: Unknown

COG id: COG0517

COG function: function code R; FOG: CBS domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000644
- InterPro:   IPR003115
- InterPro:   IPR016427 [H]

Pfam domain/function: PF00571 CBS; PF02195 ParBc [H]

EC number: 1.1.1.205

Molecular weight: Translated: 30295; Mature: 30164

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKALVRDYMTRDVITVSSDTSTAEIIKLMKETGHDGFPVKDNGSVIGMVTAFDLLIKP
CCCHHHHHHHHHHCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHH
WVKTVSEIMSRDVVVADQDMSLNDAARVMFRMGISRLPVINKEGKLVGIITNTDIVRSHI
HHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHCHHHCCEECCCCCEEEEEECHHHHHHHH
ERSTPMKVNYFKKTLEQLYGVKPEVKRMKVPIEKLRPTQNKVYADELQGRTYEIKRGLAE
HCCCCCCHHHHHHHHHHHHCCCCCHHHHCCCHHHCCCCCCCEEHHHHCCCEEHHHCCCCC
PTIVVKTGERYVLIDGHHRTLASYRLGCKEIDSYVIDIKKDMKLGMEKTADLNGVHTLED
CEEEEEECCEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCHHH
IEVIDDAQHPLIAITTSMRKAMAGKKNGR
HHHHCCCCCCEEEEHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SNKALVRDYMTRDVITVSSDTSTAEIIKLMKETGHDGFPVKDNGSVIGMVTAFDLLIKP
CCHHHHHHHHHHCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHH
WVKTVSEIMSRDVVVADQDMSLNDAARVMFRMGISRLPVINKEGKLVGIITNTDIVRSHI
HHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHCHHHCCEECCCCCEEEEEECHHHHHHHH
ERSTPMKVNYFKKTLEQLYGVKPEVKRMKVPIEKLRPTQNKVYADELQGRTYEIKRGLAE
HCCCCCCHHHHHHHHHHHHCCCCCHHHHCCCHHHCCCCCCCEEHHHHCCCEEHHHCCCCC
PTIVVKTGERYVLIDGHHRTLASYRLGCKEIDSYVIDIKKDMKLGMEKTADLNGVHTLED
CEEEEEECCEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCHHH
IEVIDDAQHPLIAITTSMRKAMAGKKNGR
HHHHCCCCCCEEEEHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: inosine 5'-phosphate; NAD+; H2O

Specific reaction: inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]