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Identifier: 15679182

GI number: 15679182

Start: 1077512

End: 1078828

Strand: Direct

Name: Not Available

Synonym: MTH1171

Alternate gene names: 15679182

Gene position: 1077512-1078828 (Clockwise)

Preceding gene: 15679181

Following gene: 15679193

Centisome position: 61.52

GC content: 50.87

Gene sequence:

>1317_bases
ATGAGTCGTGTAACTGTTGTAACACCTGAACACTACAATTACGGTTCAATGCTCATTGCAGGAGCCCTTAGGGACCTTGG
ACACAGGGTTGAAATCAGAAAGGGATTTGATGGTGTTAAATCAGAGATCGTATTCATAAGCCTTCAGTCCACCATCCACC
TCCTGAGATACAGGGATATTATTAATAAAATGGGCGGCTTCAGGGTGGTGGGGGGTCCGGTCAGCATAGACCCTGAGATG
GTATTCAGGTACCTCGATGTGGACCTCGTGGTGATGGGTGAGGGTGAGGACAAGGTCGGTCCTGTGATGGAGCTTGCAGC
TGGAAATTGTAAACCAGAGGATGTCCCCGGTGCAGCCTTCAGATCACCGGAGGGAATTGTGGTCAGTGAATCATCACCCT
GCCCCATGGAGAGGCCCCTACCCCTTGTTCCAGGTGATATCTCCAGGGAGGATATACGGGGTGCCAGTGTCTACATTGAA
ACCCACAGGGGATGTCCCGGTAACTGCACCTTCTGTCAGGTCCCTGAATTCTTTGGCAGAAATGTGAGGAGCAGGCCCCT
AAAGGACATAATCATGGAGGTCCGGGAACTGAAGTCATCGGGTGCCAGGAGGTTCGCCATAAGTGGAGGTACAGGCACCC
TCTATGGCAGCAGCAAATTCAGGGGTATTGATGAGGAAGCCTTCAGGGATCTTCTGAGGTGCATAAGTGAGGTCACCGGC
AGTAGAAACCTCACCGTGCCGGATATAAGGGTCGATATGGTCAGCCCAGAGATTCTTGATGCCATATCAGAGTACACGAA
TGGATGGGTCTTCTATGGTATAGAATCCGGGAGCAGGAGAATGCTCAGGAAGATGAAGAAGGGCATAACCCCTGATCAGG
TTGTTGAGGCCGTTGAACTTGCAAGGGAGTACAACTTAAAAGTTGCAGGCTCCTTCATCGTCGGTTACCCTGGTGAGGAC
GATGATGACTACCAGGAGACCCTTGAACTTGCAGATGAACTCATGCTGGATGACTACTTCGTGAGCATAGCCGAGCCACT
GCCCGGTACTGAACTCGGTGAGGAGGTCATGGAACTCCCTGAGGATGAAAACCCGGTATTCATGAAGTCCAGTAACAGGC
GATTTGATAGTCTGGCAGAGGAGAGGGCCTTCAATTTACTCCTGGAATCCTATGTATTCCGAAGTGTGCCGGTCCCCATG
ACGTCCAGGCTTTTAAAGTCAATAACTGAGGAGGTTCGTCAGCAGCAGGAGCATATAAGAACCGTTACCGGATGCTCAAG
GGAAAGCTGTGATGGATTCGGAGGTTTATCACTCTGA

Upstream 100 bases:

>100_bases
GGGAGATGAGTGGCACCCTCTCAGAGTATGACGTGATCGAGAGGGAGATGGAAGCCTTCTATGAACTCATACAGGCAATA
AATTTCTTTGGTGCTTCTGA

Downstream 100 bases:

>100_bases
AAATTTCATGGATGCATTTTTAATGACCTCCTCAAGGGATGATCCCTCTGGAGGTACTTTTCCAAGAAGATAATCCGAAA
AAAGAAGTTCTGGACCCTCT

Product: phosphonoacetaldehyde methylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MSRVTVVTPEHYNYGSMLIAGALRDLGHRVEIRKGFDGVKSEIVFISLQSTIHLLRYRDIINKMGGFRVVGGPVSIDPEM
VFRYLDVDLVVMGEGEDKVGPVMELAAGNCKPEDVPGAAFRSPEGIVVSESSPCPMERPLPLVPGDISREDIRGASVYIE
THRGCPGNCTFCQVPEFFGRNVRSRPLKDIIMEVRELKSSGARRFAISGGTGTLYGSSKFRGIDEEAFRDLLRCISEVTG
SRNLTVPDIRVDMVSPEILDAISEYTNGWVFYGIESGSRRMLRKMKKGITPDQVVEAVELAREYNLKVAGSFIVGYPGED
DDDYQETLELADELMLDDYFVSIAEPLPGTELGEEVMELPEDENPVFMKSSNRRFDSLAEERAFNLLLESYVFRSVPVPM
TSRLLKSITEEVRQQQEHIRTVTGCSRESCDGFGGLSL

Sequences:

>Translated_438_residues
MSRVTVVTPEHYNYGSMLIAGALRDLGHRVEIRKGFDGVKSEIVFISLQSTIHLLRYRDIINKMGGFRVVGGPVSIDPEM
VFRYLDVDLVVMGEGEDKVGPVMELAAGNCKPEDVPGAAFRSPEGIVVSESSPCPMERPLPLVPGDISREDIRGASVYIE
THRGCPGNCTFCQVPEFFGRNVRSRPLKDIIMEVRELKSSGARRFAISGGTGTLYGSSKFRGIDEEAFRDLLRCISEVTG
SRNLTVPDIRVDMVSPEILDAISEYTNGWVFYGIESGSRRMLRKMKKGITPDQVVEAVELAREYNLKVAGSFIVGYPGED
DDDYQETLELADELMLDDYFVSIAEPLPGTELGEEVMELPEDENPVFMKSSNRRFDSLAEERAFNLLLESYVFRSVPVPM
TSRLLKSITEEVRQQQEHIRTVTGCSRESCDGFGGLSL
>Mature_437_residues
SRVTVVTPEHYNYGSMLIAGALRDLGHRVEIRKGFDGVKSEIVFISLQSTIHLLRYRDIINKMGGFRVVGGPVSIDPEMV
FRYLDVDLVVMGEGEDKVGPVMELAAGNCKPEDVPGAAFRSPEGIVVSESSPCPMERPLPLVPGDISREDIRGASVYIET
HRGCPGNCTFCQVPEFFGRNVRSRPLKDIIMEVRELKSSGARRFAISGGTGTLYGSSKFRGIDEEAFRDLLRCISEVTGS
RNLTVPDIRVDMVSPEILDAISEYTNGWVFYGIESGSRRMLRKMKKGITPDQVVEAVELAREYNLKVAGSFIVGYPGEDD
DDYQETLELADELMLDDYFVSIAEPLPGTELGEEVMELPEDENPVFMKSSNRRFDSLAEERAFNLLLESYVFRSVPVPMT
SRLLKSITEEVRQQQEHIRTVTGCSRESCDGFGGLSL

Specific function: Unknown

COG id: COG1032

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methylthiotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1786882, Length=221, Percent_Identity=28.0542986425339, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006158
- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR007197 [H]

Pfam domain/function: PF02310 B12-binding; PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 48753; Mature: 48622

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVTVVTPEHYNYGSMLIAGALRDLGHRVEIRKGFDGVKSEIVFISLQSTIHLLRYRDI
CCCEEEECCCCCCCCHHHHHHHHHHHCCEEEHHHCCCCCCCCEEEEEHHHHHHHHHHHHH
INKMGGFRVVGGPVSIDPEMVFRYLDVDLVVMGEGEDKVGPVMELAAGNCKPEDVPGAAF
HHHCCCEEEECCCCCCCHHHHHHHHCEEEEEEECCCCCCCHHHHHHCCCCCCCCCCCCCC
RSPEGIVVSESSPCPMERPLPLVPGDISREDIRGASVYIETHRGCPGNCTFCQVPEFFGR
CCCCCEEEECCCCCCCCCCCCCCCCCCCHHHCCCEEEEEEECCCCCCCCCEEECCHHHCC
NVRSRPLKDIIMEVRELKSSGARRFAISGGTGTLYGSSKFRGIDEEAFRDLLRCISEVTG
CCCCCCHHHHHHHHHHHHHCCCEEEEEECCCEEEECCCCCCCCCHHHHHHHHHHHHHHCC
SRNLTVPDIRVDMVSPEILDAISEYTNGWVFYGIESGSRRMLRKMKKGITPDQVVEAVEL
CCCCCCCCEEEEECCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHH
AREYNLKVAGSFIVGYPGEDDDDYQETLELADELMLDDYFVSIAEPLPGTELGEEVMELP
HHHCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
EDENPVFMKSSNRRFDSLAEERAFNLLLESYVFRSVPVPMTSRLLKSITEEVRQQQEHIR
CCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
TVTGCSRESCDGFGGLSL
HHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SRVTVVTPEHYNYGSMLIAGALRDLGHRVEIRKGFDGVKSEIVFISLQSTIHLLRYRDI
CCEEEECCCCCCCCHHHHHHHHHHHCCEEEHHHCCCCCCCCEEEEEHHHHHHHHHHHHH
INKMGGFRVVGGPVSIDPEMVFRYLDVDLVVMGEGEDKVGPVMELAAGNCKPEDVPGAAF
HHHCCCEEEECCCCCCCHHHHHHHHCEEEEEEECCCCCCCHHHHHHCCCCCCCCCCCCCC
RSPEGIVVSESSPCPMERPLPLVPGDISREDIRGASVYIETHRGCPGNCTFCQVPEFFGR
CCCCCEEEECCCCCCCCCCCCCCCCCCCHHHCCCEEEEEEECCCCCCCCCEEECCHHHCC
NVRSRPLKDIIMEVRELKSSGARRFAISGGTGTLYGSSKFRGIDEEAFRDLLRCISEVTG
CCCCCCHHHHHHHHHHHHHCCCEEEEEECCCEEEECCCCCCCCCHHHHHHHHHHHHHHCC
SRNLTVPDIRVDMVSPEILDAISEYTNGWVFYGIESGSRRMLRKMKKGITPDQVVEAVEL
CCCCCCCCEEEEECCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHH
AREYNLKVAGSFIVGYPGEDDDDYQETLELADELMLDDYFVSIAEPLPGTELGEEVMELP
HHHCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
EDENPVFMKSSNRRFDSLAEERAFNLLLESYVFRSVPVPMTSRLLKSITEEVRQQQEHIR
CCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
TVTGCSRESCDGFGGLSL
HHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]