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Identifier: 15678919

GI number: 15678919

Start: 816081

End: 816449

Strand: Direct

Name: Not Available

Synonym: MTH899

Alternate gene names: 15678919

Gene position: 816081-816449 (Clockwise)

Preceding gene: 15678918

Following gene: 15678920

Centisome position: 46.6

GC content: 48.51

Gene sequence:

>369_bases
ATGTTAGGTAGTACCATGAATTCATGTAACGCTGATAGACCAAGCCCCGAGCAGATTGAGAGATTGAAAGAAAGGCTTGC
TGGACTCCCGGATGAGGATAAAATAAAGAAGGAAGCAGCAGCCCTTAAGGCCCTGGCAGATCCAACCCGCCTTCTCATAA
TCTACCTCCTCTCTGAGGGTGATCTCTGCGTATGTGAAATAATGGCTGCCCTTAAAAAGCCCCAGCCAACCATTTCACAC
CACCTGAACATACTCAGGCGGGCTGGTTTCCTGAAGGCGGAGAAACGCGGTGTATGGGTCCACTACAGTCTGGCCAGTGA
TGACCTCCCATCAATGATAAAGCAAGTGATTGAAGCAAGTGATTACTAA

Upstream 100 bases:

>100_bases
GAAAACATGCCCTTGAAAGGTTCCTCCTTGGAAGTGTGTCAGAGAAGATTGTGAGACACGCCAGGGTACCTGTGCTTGTG
GTCCACAGCAAGAAACTTGA

Downstream 100 bases:

>100_bases
GGTGGTATCTTGACCGGTGATTCCTGCAGTTTAGATGGTGATATCTGTCCATCAAGGCTCGGATTTCTCGATAAATATCT
GACACTCTGGATTTTCCTTG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 122; Mature: 122

Protein sequence:

>122_residues
MLGSTMNSCNADRPSPEQIERLKERLAGLPDEDKIKKEAAALKALADPTRLLIIYLLSEGDLCVCEIMAALKKPQPTISH
HLNILRRAGFLKAEKRGVWVHYSLASDDLPSMIKQVIEASDY

Sequences:

>Translated_122_residues
MLGSTMNSCNADRPSPEQIERLKERLAGLPDEDKIKKEAAALKALADPTRLLIIYLLSEGDLCVCEIMAALKKPQPTISH
HLNILRRAGFLKAEKRGVWVHYSLASDDLPSMIKQVIEASDY
>Mature_122_residues
MLGSTMNSCNADRPSPEQIERLKERLAGLPDEDKIKKEAAALKALADPTRLLIIYLLSEGDLCVCEIMAALKKPQPTISH
HLNILRRAGFLKAEKRGVWVHYSLASDDLPSMIKQVIEASDY

Specific function: Transcriptional Repressor For The Arsefg Operon. Arse Is A Trans-Acting Regulatory Protein Which Controls Its Own Expression. The Repressive Effect Of Arse Is Alleviated By Oxyions Of +III Oxidation State Of Arsenic, Antimony, And Bismuth, As Well As Arse

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=78, Percent_Identity=50, Blast_Score=73, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 13586; Mature: 13586

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGSTMNSCNADRPSPEQIERLKERLAGLPDEDKIKKEAAALKALADPTRLLIIYLLSEG
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHEECCCC
DLCVCEIMAALKKPQPTISHHLNILRRAGFLKAEKRGVWVHYSLASDDLPSMIKQVIEAS
CCHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHCCCCEEEEEECCCCCHHHHHHHHHHHC
DY
CC
>Mature Secondary Structure
MLGSTMNSCNADRPSPEQIERLKERLAGLPDEDKIKKEAAALKALADPTRLLIIYLLSEG
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHEECCCC
DLCVCEIMAALKKPQPTISHHLNILRRAGFLKAEKRGVWVHYSLASDDLPSMIKQVIEAS
CCHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHCCCCEEEEEECCCCCHHHHHHHHHHHC
DY
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]