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Identifier: 15678876

GI number: 15678876

Start: 778950

End: 780314

Strand: Direct

Name: Not Available

Synonym: MTH856

Alternate gene names: 15678876

Gene position: 778950-780314 (Clockwise)

Preceding gene: 15678871

Following gene: 15678877

Centisome position: 44.48

GC content: 54.21

Gene sequence:

>1365_bases
ATGGAGATTGACACTGATTATCTTGGCAGCATACTCATGGACATAGAGGATAGGGTGGAATATGCAGATATAAGGGCTGG
CACCTCCCGGACCAGTTCCATTCTGATGAAGGACGGTAAACTGCAGGAGGTTAAATCCGGGAGAGCCTCTGGTTTCAGGA
TAAGGGTGCTGAGGAATGGTTCATGGGGATTCGCCTTTACAGATGAACCCTCCAGGCTCGGTGAAATGGCCCTTAAGGCC
ATAAAGATGACCGGGTCCCTCAGGGGCGATGTCCAGGTGGGTTCAGGTGCCCCCTCTGTTGACAAAACCATGGTAAGGTC
ATCCCGGCCGCCCTCAGATGTTCCTGCAGCTGAGAAGCGGGAGCTGGTATCAGATGCACACCATGCCGCATCAGTTGATG
GTGTTGTGAGCACCACTGTGAGCTACGTTGACATGGAGAGCTCATCTGCCTTCCTGAACTCAGAGGGGTCACTCATTGAG
ATGGCTGAGACCAGGGTCGCCCTCTTTCTAAACGCTGTTGCATCGGATGGCTCCGGGATACAGTTCGGCCACAAAAGCTG
CGGTGGAACCGGTGGCTTCGAAATACTGGAGAGGGAGGACATTGAGGAGCTCGGTCGCAGGACCGGTGAAAAGGCTGTTA
GGCTCCTCAAGGCGAGTCCGCCGCCATCAGGACGCTTTGATATAGTAACTGACCCCGAACTTACGGGTGTATTCATACAT
GAGGCACTGGGGCACGCAGCCGAGGCAGACCTCATACTGCAGGGTGACTCCATACTCGAGGGTAAACTGGGGGAGAAGAT
TGCCTCTGAGGGTGTTACCATCATCGACGACCCTACGATTGATGGTTTTGGGAGTTACAGCTACGATGCAGAGGGTGTGA
GGGCCGCTGAAACCGTTCTAGTGGAGAACGGCGTCCTCACTTCACTCCTTAACTCCAGGGAAACAGCCTTCAAACTTGGT
CTTGAACCATCAGGGAATGCCCGTTCAGCCATAGGGGACCAGCCCATTGTCAGGATGAGCAACACATACCTCAAACCAGG
CGATTTATCCTTCGATGAACTCATAGAGGATATCCGGAATGGTGTCTACCTGAGGGGTTCAAGGGGGGGCCAGGTGGATA
CCGGTAAGGGCATCTTCCAGTTCAATGCTGCTGAGTCATTCCGTATACAGGATGGTGAAATTGCAGAACCCGTCAAGGAT
GTCTCCCTCTCAGGAAACGTCCTGGAGACCCTCAAAAATGTTGACGGGGTTGGTTCAGACTTCAGGCTGGGGATTGGCTT
CTGCGGGAAATCCGGGCAGAGCGTCCCTGTGGGCGATGGGGGCCCCCACGTGAGGATAAGGAATGCCATGGTGGGTGGAA
CATGA

Upstream 100 bases:

>100_bases
TTCACAGAACCACTGCATGTGAACTTCAGTGTGACATCAAAAGAATCATAAGCACCCACCTACAGAATTAATAAGAGAAA
CTTTTGAAGGCTGATGGGAA

Downstream 100 bases:

>100_bases
AGTACGCGCCATTATCCCGGGATGAAGGTAGAACTCTTGTTAAAATCGCGAGGATGGCCATAGAGGAGCACCTGCGTGGA
TCAAAAAACCTCAGACTCCC

Product: zinc metalloproteinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MEIDTDYLGSILMDIEDRVEYADIRAGTSRTSSILMKDGKLQEVKSGRASGFRIRVLRNGSWGFAFTDEPSRLGEMALKA
IKMTGSLRGDVQVGSGAPSVDKTMVRSSRPPSDVPAAEKRELVSDAHHAASVDGVVSTTVSYVDMESSSAFLNSEGSLIE
MAETRVALFLNAVASDGSGIQFGHKSCGGTGGFEILEREDIEELGRRTGEKAVRLLKASPPPSGRFDIVTDPELTGVFIH
EALGHAAEADLILQGDSILEGKLGEKIASEGVTIIDDPTIDGFGSYSYDAEGVRAAETVLVENGVLTSLLNSRETAFKLG
LEPSGNARSAIGDQPIVRMSNTYLKPGDLSFDELIEDIRNGVYLRGSRGGQVDTGKGIFQFNAAESFRIQDGEIAEPVKD
VSLSGNVLETLKNVDGVGSDFRLGIGFCGKSGQSVPVGDGGPHVRIRNAMVGGT

Sequences:

>Translated_454_residues
MEIDTDYLGSILMDIEDRVEYADIRAGTSRTSSILMKDGKLQEVKSGRASGFRIRVLRNGSWGFAFTDEPSRLGEMALKA
IKMTGSLRGDVQVGSGAPSVDKTMVRSSRPPSDVPAAEKRELVSDAHHAASVDGVVSTTVSYVDMESSSAFLNSEGSLIE
MAETRVALFLNAVASDGSGIQFGHKSCGGTGGFEILEREDIEELGRRTGEKAVRLLKASPPPSGRFDIVTDPELTGVFIH
EALGHAAEADLILQGDSILEGKLGEKIASEGVTIIDDPTIDGFGSYSYDAEGVRAAETVLVENGVLTSLLNSRETAFKLG
LEPSGNARSAIGDQPIVRMSNTYLKPGDLSFDELIEDIRNGVYLRGSRGGQVDTGKGIFQFNAAESFRIQDGEIAEPVKD
VSLSGNVLETLKNVDGVGSDFRLGIGFCGKSGQSVPVGDGGPHVRIRNAMVGGT
>Mature_454_residues
MEIDTDYLGSILMDIEDRVEYADIRAGTSRTSSILMKDGKLQEVKSGRASGFRIRVLRNGSWGFAFTDEPSRLGEMALKA
IKMTGSLRGDVQVGSGAPSVDKTMVRSSRPPSDVPAAEKRELVSDAHHAASVDGVVSTTVSYVDMESSSAFLNSEGSLIE
MAETRVALFLNAVASDGSGIQFGHKSCGGTGGFEILEREDIEELGRRTGEKAVRLLKASPPPSGRFDIVTDPELTGVFIH
EALGHAAEADLILQGDSILEGKLGEKIASEGVTIIDDPTIDGFGSYSYDAEGVRAAETVLVENGVLTSLLNSRETAFKLG
LEPSGNARSAIGDQPIVRMSNTYLKPGDLSFDELIEDIRNGVYLRGSRGGQVDTGKGIFQFNAAESFRIQDGEIAEPVKD
VSLSGNVLETLKNVDGVGSDFRLGIGFCGKSGQSVPVGDGGPHVRIRNAMVGGT

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family

Homologues:

Organism=Escherichia coli, GI1789640, Length=451, Percent_Identity=31.0421286031042, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1790682, Length=317, Percent_Identity=25.8675078864353, Blast_Score=80, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y856_METTH (O26944)

Other databases:

- EMBL:   AE000666
- PIR:   C69214
- RefSeq:   NP_275993.1
- STRING:   O26944
- GeneID:   1471264
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH856
- NMPDR:   fig|187420.1.peg.848
- eggNOG:   arNOG04075
- HOGENOM:   HBG726714
- OMA:   GQVDTGK
- PhylomeDB:   O26944
- ProtClustDB:   CLSK2517832
- BioCyc:   MTHE187420:MTH856-MONOMER
- InterPro:   IPR002510

Pfam domain/function: PF01523 PmbA_TldD

EC number: NA

Molecular weight: Translated: 48156; Mature: 48156

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIDTDYLGSILMDIEDRVEYADIRAGTSRTSSILMKDGKLQEVKSGRASGFRIRVLRNG
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHCCCCCCEEEEEEECC
SWGFAFTDEPSRLGEMALKAIKMTGSLRGDVQVGSGAPSVDKTMVRSSRPPSDVPAAEKR
CCCEEECCCHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHCCCCCCCCCCHHHH
ELVSDAHHAASVDGVVSTTVSYVDMESSSAFLNSEGSLIEMAETRVALFLNAVASDGSGI
HHHHHHHHHHCCCHHHHHHEEEEEECCCCCEECCCCCEEEHHHHHHHHHHHHHHCCCCCC
QFGHKSCGGTGGFEILEREDIEELGRRTGEKAVRLLKASPPPSGRFDIVTDPELTGVFIH
CCCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHH
EALGHAAEADLILQGDSILEGKLGEKIASEGVTIIDDPTIDGFGSYSYDAEGVRAAETVL
HHHCCCCCCCEEEECCCCCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCHHHHEEE
VENGVLTSLLNSRETAFKLGLEPSGNARSAIGDQPIVRMSNTYLKPGDLSFDELIEDIRN
ECCCHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHC
GVYLRGSRGGQVDTGKGIFQFNAAESFRIQDGEIAEPVKDVSLSGNVLETLKNVDGVGSD
CEEEECCCCCCCCCCCCEEEECCCCCEEECCCCHHCHHHHCCCCCHHHHHHHHCCCCCCC
FRLGIGFCGKSGQSVPVGDGGPHVRIRNAMVGGT
EEEEEEEECCCCCCCCCCCCCCCEEEECEECCCC
>Mature Secondary Structure
MEIDTDYLGSILMDIEDRVEYADIRAGTSRTSSILMKDGKLQEVKSGRASGFRIRVLRNG
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHCCCCCCEEEEEEECC
SWGFAFTDEPSRLGEMALKAIKMTGSLRGDVQVGSGAPSVDKTMVRSSRPPSDVPAAEKR
CCCEEECCCHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHCCCCCCCCCCHHHH
ELVSDAHHAASVDGVVSTTVSYVDMESSSAFLNSEGSLIEMAETRVALFLNAVASDGSGI
HHHHHHHHHHCCCHHHHHHEEEEEECCCCCEECCCCCEEEHHHHHHHHHHHHHHCCCCCC
QFGHKSCGGTGGFEILEREDIEELGRRTGEKAVRLLKASPPPSGRFDIVTDPELTGVFIH
CCCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHH
EALGHAAEADLILQGDSILEGKLGEKIASEGVTIIDDPTIDGFGSYSYDAEGVRAAETVL
HHHCCCCCCCEEEECCCCCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCHHHHEEE
VENGVLTSLLNSRETAFKLGLEPSGNARSAIGDQPIVRMSNTYLKPGDLSFDELIEDIRN
ECCCHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHC
GVYLRGSRGGQVDTGKGIFQFNAAESFRIQDGEIAEPVKDVSLSGNVLETLKNVDGVGSD
CEEEECCCCCCCCCCCCEEEECCCCCEEECCCCHHCHHHHCCCCCHHHHHHHHCCCCCCC
FRLGIGFCGKSGQSVPVGDGGPHVRIRNAMVGGT
EEEEEEEECCCCCCCCCCCCCCCEEEECEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463