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Identifier: 15678828

GI number: 15678828

Start: 733590

End: 734453

Strand: Direct

Name: Not Available

Synonym: MTH806

Alternate gene names: 15678828

Gene position: 733590-734453 (Clockwise)

Preceding gene: 15678818

Following gene: 15678829

Centisome position: 41.89

GC content: 52.66

Gene sequence:

>864_bases
ATGGATAGAAACAGCAAGATAGTAGTCGGTCTCGTCGCGGTCCTCTCAATCGCAGGTTTGGTGCTTTCATTAGCCGGTCT
GCTGGAGGGCGGCGAGGGTACGATAGCAATAATACCTGTCCACGGAGCCATAGCCTATGACACGGCAGGGTTCTCTGATG
GAGTGGACCCTGATGACATAAAGGAGCTCATCGCTGAAGCCAACAGCGATCCCTCAGTTAAGGCCATTGTCCTCGACATA
AACAGCCCGGGAGGGACACCTGTTGCAAGTGAGGAACTCATGGATGCCATAAATAAATCAGAAAAACCAGTGGTGAGCTG
GATAAGTGATTCAGGGACCTCGGGGGCATACCTTGCAGCATCAGCCTCTGACAGGATAGTTGCGAGTCCCTCAGCATGGG
TTGGAAGCATAGGTGTCATACTCGACCTTACGGATCTCTCCCAGATGTACAGGCAGATGGGGATAAACAAGTACGCCATA
AAGGCCGGTGAGTACAAGGACATGGGTGCCGATTACCGCATGATAACCGATGAGGAGAGACAGATGCTGCAGTCAATGGT
CAATGAGGAGTACGACTACTTCATAAAGACCGTGGCTGCCAACAGAAACCTTAGCGTCTCCTACGTGAAGAGCCTGGCAG
AGGGCCGGATATTCACAGGCAGACAGGCTGTACGCAACCGGCTGGTGGATTTCACTGGAGGGAAGGACTATGCAGTTGAG
GTGGCTGCGAAGCTCGCAGGTGTGAAGAACTATAACACGATAACCCTCGAGCCTCCTTCTGGCTTCCTAAGGGTCCTCTC
CAGCATGTTCTCAAGGCTGGGATTTGCCTCAGGGAACACAACGGAAGAGCTGCAGCTCCATTGA

Upstream 100 bases:

>100_bases
TTCTATTAATAAAAATGGTTAAAAATTTAGGATGGTACATGGATGTCTGATATAACAAAAACTCCTGAAAACATGACTGG
AGGTAAAAAGGTCTGATACC

Downstream 100 bases:

>100_bases
TGAAGGTGGAAAAGGATAAGTATTTATCTAAAAAGGGGAAGAAGATAATTATATTACTCTCACGGAGGTTAAGAAATGGT
TGTTAATATAGAGGTTTTCA

Product: protease IV

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MDRNSKIVVGLVAVLSIAGLVLSLAGLLEGGEGTIAIIPVHGAIAYDTAGFSDGVDPDDIKELIAEANSDPSVKAIVLDI
NSPGGTPVASEELMDAINKSEKPVVSWISDSGTSGAYLAASASDRIVASPSAWVGSIGVILDLTDLSQMYRQMGINKYAI
KAGEYKDMGADYRMITDEERQMLQSMVNEEYDYFIKTVAANRNLSVSYVKSLAEGRIFTGRQAVRNRLVDFTGGKDYAVE
VAAKLAGVKNYNTITLEPPSGFLRVLSSMFSRLGFASGNTTEELQLH

Sequences:

>Translated_287_residues
MDRNSKIVVGLVAVLSIAGLVLSLAGLLEGGEGTIAIIPVHGAIAYDTAGFSDGVDPDDIKELIAEANSDPSVKAIVLDI
NSPGGTPVASEELMDAINKSEKPVVSWISDSGTSGAYLAASASDRIVASPSAWVGSIGVILDLTDLSQMYRQMGINKYAI
KAGEYKDMGADYRMITDEERQMLQSMVNEEYDYFIKTVAANRNLSVSYVKSLAEGRIFTGRQAVRNRLVDFTGGKDYAVE
VAAKLAGVKNYNTITLEPPSGFLRVLSSMFSRLGFASGNTTEELQLH
>Mature_287_residues
MDRNSKIVVGLVAVLSIAGLVLSLAGLLEGGEGTIAIIPVHGAIAYDTAGFSDGVDPDDIKELIAEANSDPSVKAIVLDI
NSPGGTPVASEELMDAINKSEKPVVSWISDSGTSGAYLAASASDRIVASPSAWVGSIGVILDLTDLSQMYRQMGINKYAI
KAGEYKDMGADYRMITDEERQMLQSMVNEEYDYFIKTVAANRNLSVSYVKSLAEGRIFTGRQAVRNRLVDFTGGKDYAVE
VAAKLAGVKNYNTITLEPPSGFLRVLSSMFSRLGFASGNTTEELQLH

Specific function: Digestion Of The Cleaved Signal Peptides. This Activity Is Necessary To Maintain Proper Secretion Of Mature Proteins Across The Membrane. [C]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1788064, Length=240, Percent_Identity=32.0833333333333, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1787527, Length=160, Percent_Identity=30.625, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 30657; Mature: 30657

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRNSKIVVGLVAVLSIAGLVLSLAGLLEGGEGTIAIIPVHGAIAYDTAGFSDGVDPDDI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEEECCCCCCCCCCHHHH
KELIAEANSDPSVKAIVLDINSPGGTPVASEELMDAINKSEKPVVSWISDSGTSGAYLAA
HHHHHHCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCEEEEE
SASDRIVASPSAWVGSIGVILDLTDLSQMYRQMGINKYAIKAGEYKDMGADYRMITDEER
CCCCCEEECCCHHHCCHHHEEEHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEECHHHH
QMLQSMVNEEYDYFIKTVAANRNLSVSYVKSLAEGRIFTGRQAVRNRLVDFTGGKDYAVE
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEECCHHHHHHHHEECCCCCHHHHH
VAAKLAGVKNYNTITLEPPSGFLRVLSSMFSRLGFASGNTTEELQLH
HHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCEEEEC
>Mature Secondary Structure
MDRNSKIVVGLVAVLSIAGLVLSLAGLLEGGEGTIAIIPVHGAIAYDTAGFSDGVDPDDI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEEECCCCCCCCCCHHHH
KELIAEANSDPSVKAIVLDINSPGGTPVASEELMDAINKSEKPVVSWISDSGTSGAYLAA
HHHHHHCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCEEEEE
SASDRIVASPSAWVGSIGVILDLTDLSQMYRQMGINKYAIKAGEYKDMGADYRMITDEER
CCCCCEEECCCHHHCCHHHEEEHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEECHHHH
QMLQSMVNEEYDYFIKTVAANRNLSVSYVKSLAEGRIFTGRQAVRNRLVDFTGGKDYAVE
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEECCHHHHHHHHEECCCCCHHHHH
VAAKLAGVKNYNTITLEPPSGFLRVLSSMFSRLGFASGNTTEELQLH
HHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]