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Identifier: 15678607

GI number: 15678607

Start: 518398

End: 519198

Strand: Direct

Name: Not Available

Synonym: MTH579

Alternate gene names: 15678607

Gene position: 518398-519198 (Clockwise)

Preceding gene: 15678606

Following gene: 15678608

Centisome position: 29.6

GC content: 56.18

Gene sequence:

>801_bases
ATGATAGGCAAAAGGATTAGGATTGAGAGGATAATCAACAGGAAGACGGACAGGACTGTCATAGTACCCCTCGATCACGG
AGTCTCCATTGGACCCGTTCGCGGGATAATCGACATGGCAGGCACCATAGATGAGGTTGCAAGTGGCGGTGCAAACGCCG
TTCTCATGCACAAGGGAATGGTCAGGAGTGGACACAGGGGATACGGGAGGGACATAGGACTCATAATACACCTCTCGGCC
AGCACAGGCCTCGGCCCCGACCCAAACCACAAGGTCCTTGTGACCTCAGTTGAGAAGGCCCTCAAGCTGGGTGCCGACGC
GGTATCCGTCCATGTGAATGTGGGATCCGAAAGGGAACCCGAGATGCTGATAAAACTCGGAACCGTTGCAGAGATCTGTG
ATGACTGGGGCATGCCCCTCATTGCCATGATGTACCCCAGGGGTAAGAAGATAGATGATGAGCACGACCCGGAGGTCGTG
AAGCTGGCAGCCCGTGCAGGCGCAGAGCTCGGTGCAGACATAATAAAGACCAACTACACCGGTGACCCTGACACCTTCAG
GGACGTTGTGAAGGGGTGCCCGGTCCCTGTGGTGATAGCTGGCGGACCAAAGATAGAGACAGAGGAGGAGCTACTCCAGA
TGGTCAGTGACTCTGTGGAGGCAGGGGGCGCAGGGGTCGCCATTGGAAGGAACATATTCCAGGCCGATTCACCTGCAAAC
ATGACAGGGGCCATAGCAGGCATAGTCCATGATGGCCTGAGTGTCGAGGAGGCCGTCAGGATACTGAAGGGTGGCGAGTG
A

Upstream 100 bases:

>100_bases
TCCAGGTATGGATGGCTTGAGTCAAGTGGGGACGCTGGAATCCCCCCACGACTCAGGGAATTTAAGCTCTGGTCCAGCAA
GATATACAAGGAGGGTGCCC

Downstream 100 bases:

>100_bases
GATGAAGTTCGCATGGCTCCTGGCCCCCGACACCTACTGGGATGAGAAGAAGACCTTCATAACGGCGGCCCTGGAATCAG
GGATAGACCACATAGTGGAC

Product: fructose-bisphosphate aldolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MIGKRIRIERIINRKTDRTVIVPLDHGVSIGPVRGIIDMAGTIDEVASGGANAVLMHKGMVRSGHRGYGRDIGLIIHLSA
STGLGPDPNHKVLVTSVEKALKLGADAVSVHVNVGSEREPEMLIKLGTVAEICDDWGMPLIAMMYPRGKKIDDEHDPEVV
KLAARAGAELGADIIKTNYTGDPDTFRDVVKGCPVPVVIAGGPKIETEEELLQMVSDSVEAGGAGVAIGRNIFQADSPAN
MTGAIAGIVHDGLSVEEAVRILKGGE

Sequences:

>Translated_266_residues
MIGKRIRIERIINRKTDRTVIVPLDHGVSIGPVRGIIDMAGTIDEVASGGANAVLMHKGMVRSGHRGYGRDIGLIIHLSA
STGLGPDPNHKVLVTSVEKALKLGADAVSVHVNVGSEREPEMLIKLGTVAEICDDWGMPLIAMMYPRGKKIDDEHDPEVV
KLAARAGAELGADIIKTNYTGDPDTFRDVVKGCPVPVVIAGGPKIETEEELLQMVSDSVEAGGAGVAIGRNIFQADSPAN
MTGAIAGIVHDGLSVEEAVRILKGGE
>Mature_266_residues
MIGKRIRIERIINRKTDRTVIVPLDHGVSIGPVRGIIDMAGTIDEVASGGANAVLMHKGMVRSGHRGYGRDIGLIIHLSA
STGLGPDPNHKVLVTSVEKALKLGADAVSVHVNVGSEREPEMLIKLGTVAEICDDWGMPLIAMMYPRGKKIDDEHDPEVV
KLAARAGAELGADIIKTNYTGDPDTFRDVVKGCPVPVVIAGGPKIETEEELLQMVSDSVEAGGAGVAIGRNIFQADSPAN
MTGAIAGIVHDGLSVEEAVRILKGGE

Specific function: Unknown

COG id: COG1830

COG function: function code G; DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family

Homologues:

Organism=Escherichia coli, GI1787796, Length=264, Percent_Identity=31.8181818181818, Blast_Score=126, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y579_METTH (O26679)

Other databases:

- EMBL:   AE000666
- PIR:   F69176
- RefSeq:   NP_275722.1
- ProteinModelPortal:   O26679
- SMR:   O26679
- STRING:   O26679
- GeneID:   1470540
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH579
- NMPDR:   fig|187420.1.peg.577
- eggNOG:   arNOG05005
- HOGENOM:   HBG553580
- OMA:   DPNHKVL
- ProtClustDB:   PRK07226
- BioCyc:   MTHE187420:MTH579-MONOMER
- InterPro:   IPR013785
- InterPro:   IPR010210
- InterPro:   IPR002915
- Gene3D:   G3DSA:3.20.20.70
- TIGRFAMs:   TIGR01949

Pfam domain/function: PF01791 DeoC

EC number: 4.2.1.- [C]

Molecular weight: Translated: 28014; Mature: 28014

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: ACT_SITE 176-176

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGKRIRIERIINRKTDRTVIVPLDHGVSIGPVRGIIDMAGTIDEVASGGANAVLMHKGM
CCCCHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCHHHHHCCCCCEEEEECCH
VRSGHRGYGRDIGLIIHLSASTGLGPDPNHKVLVTSVEKALKLGADAVSVHVNVGSEREP
HHCCCCCCCCCEEEEEEEECCCCCCCCCCCCEEEEEHHHHHHCCCCEEEEEEECCCCCCC
EMLIKLGTVAEICDDWGMPLIAMMYPRGKKIDDEHDPEVVKLAARAGAELGADIIKTNYT
HHEEEHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCHHHCHHHHCCCCC
GDPDTFRDVVKGCPVPVVIAGGPKIETEEELLQMVSDSVEAGGAGVAIGRNIFQADSPAN
CCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEECCCHHHCCCCCCC
MTGAIAGIVHDGLSVEEAVRILKGGE
HHHHHHHHHHCCCCHHHHHHHHCCCC
>Mature Secondary Structure
MIGKRIRIERIINRKTDRTVIVPLDHGVSIGPVRGIIDMAGTIDEVASGGANAVLMHKGM
CCCCHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCHHHHHCCCCCEEEEECCH
VRSGHRGYGRDIGLIIHLSASTGLGPDPNHKVLVTSVEKALKLGADAVSVHVNVGSEREP
HHCCCCCCCCCEEEEEEEECCCCCCCCCCCCEEEEEHHHHHHCCCCEEEEEEECCCCCCC
EMLIKLGTVAEICDDWGMPLIAMMYPRGKKIDDEHDPEVVKLAARAGAELGADIIKTNYT
HHEEEHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCHHHCHHHHCCCCC
GDPDTFRDVVKGCPVPVVIAGGPKIETEEELLQMVSDSVEAGGAGVAIGRNIFQADSPAN
CCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEECCCHHHCCCCCCC
MTGAIAGIVHDGLSVEEAVRILKGGE
HHHHHHHHHHCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463