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Identifier: 15678579

GI number: 15678579

Start: 496698

End: 499259

Strand: Direct

Name: Not Available

Synonym: MTH551

Alternate gene names: NA

Gene position: 496698-499259 (Clockwise)

Preceding gene: 15678574

Following gene: 15678585

Centisome position: 28.36

GC content: 46.64

Gene sequence:

>2562_bases
TTGAGTGATGGGAGGGCAAATCCTTCAGAGAAAGTGAACCTGAGCCTTGCTGAAGAATCTTTCATTACATTCCTCCAGGA
TAATCTTCCTGATGACTGGAAAATCTATTTTAAACCTCATCTTAACGGTTCCTACCCTGACCTCATAATCATGAACCCCC
ATGTCGGGATAATGATCTACAGTATCCTTGATGAAGTCAACTGCACCCCTGAAGCTGAAATAAGGCGACTGGGATATTAC
AAGAAGAAGATAATACGGCAGCTGGTCCCATCCATGGGTGAGATGATTGATAAAGAGAGGAGCGCCTATGGTATCATCCG
GACAGGTGTATATGTTCATGGACTATCCAGCAGGGAAGTTAAGGATAAGTTCAAATCTGGAGGGAGTTACCTTACCTGTG
CCGGCCATGACAGCCTTCAGAAATCAAACCTGGAGGCCCTGATACCCGGTCTGAGGTTCCGTAAGAGCAAATACATGAAA
CCTGAATGGGCATCGCAGCTTGAATCCTGGATGGTCCCCAGCTATCACAGGGAGAAAAGGACTGATATCAGGCTTACAGA
GGAGCAGGAACGACATGTAAAGCCACAACCAGGACACAGAAGACTCAGAGGAGCTGCTGGGAGTGGTAAAACTCTGGTAA
TAGCCCACAGAGCAGCGCGACTGGCTGCTGATGGGCACCGCGTACTCATAGTAACCTTTAACAGCACACTCTGGCAGTAT
ATCAGGGAGATGGTGGATAGGACCCTCTACAACTTTGACTGGTCCCTCCTGACGTTCAGGCACTTCCACGGGTTCTGCTA
CGACATTATACATGAGCTTAAAATCCCCTTTGACCAGGAGAGGGTTGTCGAGTGTCTCATAGGGTCAATCCGGGACCATG
ATATTTCAGAATACATGTTTGATGCTGTCCTTATTGATGAGGGCCAGGATTTTGAGTGGGAATGGTACAACCTGCTATCC
CAGTTCCTGACAGAAAGGGATGAACTGTTCTTTGTATGCGACGAAAGACAGAACATATATGACAGGGAGCTCAGCTGGGT
CGACAAGATGTCAGGCGCAGGAAAGGTTAAGTTCCGGGGAAAATGGAGGGAACTTGGGACAGTTCATCGACTATCACCAA
AGATAGCTGAATTTGCAAATAAATTTGCTCAAAGTTTCCTTAGATCAGGGGATAATGAATTAGATGTCAGCCAGAAAACC
CTCTTTGATAACCGTGAAGCCGTGTGGAGAAACGTGGACCCCCATGACTGGCAGGATGAACTATATGACGCCTACAGTTC
CCTCAGGGATATGGGTGTTCGTGACTCAGAAATAGCTGTACTGGTACCCACCAATGATATGGGTGTGAAGGTTGCTGAAT
TCTTCAGATCAATGAACGTGAAAACCGACCACCTCTTCAGGAAGAATGGTGCCGGTAACAAGAGGGTATTCGTATCCGAT
GGGCGGATGAAGATAAGCACAATACACAGCTTCAAGGGATGGGAAGCAAGAAGTGTGATAATCTGGATACCTGACAGATG
GGGACAGGAAGAGAACCTTGACGCAGTCATATACACCGCGATAACCAGGACCCTTGAAAACCTCATCATACTGAACACCA
ATGAAAGGTACCTTGAATTCTATGAAAACGATGAGGACGTTGAAATTCCCGATATAACTGAAGATGAGATGGACCCTGAA
CTTGAGGAATGGATTGAGACACTCCCGTACCCACTCGCCTCCATCATCTGGGAGAGCATGACCATAACGAGCTATGAGAG
CAGGGTCAGATATCTCATTCACTTCTTTGAGGCCCTTGCAGAGTTCAACTTCAACCTCATTATGAGCGGTCTATCCTCTG
ACGAATTCTTCTTTGATATGAGGGTTAGGGAAACCTTTGGAGGTGTTAAAAATAATCTTGAAAGGCCCACCTTCGGGTAC
TGGACGGCACTCCTCTTCAGGGCAATCAGAAGCCTGAGGATGGTGCTGAATGATAGGTACCATAAAAACCAGGTCCGCAA
ATCCTTTGGAAAGCCAGATGATGACTTTATAAATGCACTGGCCAACAGCAAGCTCCCTGTAATACTGAAAAATGTTTTAA
AGTACCGTAACGTCTGGGAGGGGCATGGCCCGCGAGTTTCCGAGGATGAATACCGTAAACGTTACAGTGTACTGATAGGG
GAGCTAAGGAATGTTAAGGATGTGATCGGGGACATTTACACCCGCAATTTCCTGGTCATCCCCAGTGAGGGAATCCTGGA
TGGTGGTGTGCACCGGTACACAGCAAAGCGTTACATGACAACGAGGGCCCCCTTCAGGGCTGTGAAACTGGAAAGTGAGA
AACCCATGGACATTAACAGTATATACCTTGCAAACCCAAACAAGAGGAGGCACCTGGAACTCCTGCCCCTTATAATCAAT
AATGATGACACCTGCTACTTCTACAACGGGATTGATGATGAAACTGGTAAGGCGAGGTACTGTTCCTACCATAACAAGGA
CAAGGCTGAAATATTTGTAAACCCACCTCCTAAACTTGTAAATCTGCAAGAAATGCTGAATCAAACTGACTCCTACAATT
AA

Upstream 100 bases:

>100_bases
CATCATTAACCAGACTTTTGGTTCAGGGAAACAGTAAATTTATTAATCGTGTGGATTGAATTAATCATGTAAATGAATAT
ACTGTGGTGGGGGTTTTCAT

Downstream 100 bases:

>100_bases
TCTCCAGGCTTCATATGAGATAACTCTCTTTATTCCCAGATACATTCCCATGCAGATTTGCAGAGGAGCCTGAGACCATT
GATGATTTTGAAGAAACATT

Product: DNA helicase II related protein

Products: NA

Alternate protein names: DNA Helicase II Related Protein; NERD Domain Protein; NERD Domain-Containing Protein; Superfamily I DNA And RNA Helicase; Nerd Domain Protein; UvrD/REP Helicase; Helicase Protein; N-6 DNA Methylase; ATP-Dependent Helicase; DNA Helicase; Nuclease-Related Domain Protein

Number of amino acids: Translated: 853; Mature: 852

Protein sequence:

>853_residues
MSDGRANPSEKVNLSLAEESFITFLQDNLPDDWKIYFKPHLNGSYPDLIIMNPHVGIMIYSILDEVNCTPEAEIRRLGYY
KKKIIRQLVPSMGEMIDKERSAYGIIRTGVYVHGLSSREVKDKFKSGGSYLTCAGHDSLQKSNLEALIPGLRFRKSKYMK
PEWASQLESWMVPSYHREKRTDIRLTEEQERHVKPQPGHRRLRGAAGSGKTLVIAHRAARLAADGHRVLIVTFNSTLWQY
IREMVDRTLYNFDWSLLTFRHFHGFCYDIIHELKIPFDQERVVECLIGSIRDHDISEYMFDAVLIDEGQDFEWEWYNLLS
QFLTERDELFFVCDERQNIYDRELSWVDKMSGAGKVKFRGKWRELGTVHRLSPKIAEFANKFAQSFLRSGDNELDVSQKT
LFDNREAVWRNVDPHDWQDELYDAYSSLRDMGVRDSEIAVLVPTNDMGVKVAEFFRSMNVKTDHLFRKNGAGNKRVFVSD
GRMKISTIHSFKGWEARSVIIWIPDRWGQEENLDAVIYTAITRTLENLIILNTNERYLEFYENDEDVEIPDITEDEMDPE
LEEWIETLPYPLASIIWESMTITSYESRVRYLIHFFEALAEFNFNLIMSGLSSDEFFFDMRVRETFGGVKNNLERPTFGY
WTALLFRAIRSLRMVLNDRYHKNQVRKSFGKPDDDFINALANSKLPVILKNVLKYRNVWEGHGPRVSEDEYRKRYSVLIG
ELRNVKDVIGDIYTRNFLVIPSEGILDGGVHRYTAKRYMTTRAPFRAVKLESEKPMDINSIYLANPNKRRHLELLPLIIN
NDDTCYFYNGIDDETGKARYCSYHNKDKAEIFVNPPPKLVNLQEMLNQTDSYN

Sequences:

>Translated_853_residues
MSDGRANPSEKVNLSLAEESFITFLQDNLPDDWKIYFKPHLNGSYPDLIIMNPHVGIMIYSILDEVNCTPEAEIRRLGYY
KKKIIRQLVPSMGEMIDKERSAYGIIRTGVYVHGLSSREVKDKFKSGGSYLTCAGHDSLQKSNLEALIPGLRFRKSKYMK
PEWASQLESWMVPSYHREKRTDIRLTEEQERHVKPQPGHRRLRGAAGSGKTLVIAHRAARLAADGHRVLIVTFNSTLWQY
IREMVDRTLYNFDWSLLTFRHFHGFCYDIIHELKIPFDQERVVECLIGSIRDHDISEYMFDAVLIDEGQDFEWEWYNLLS
QFLTERDELFFVCDERQNIYDRELSWVDKMSGAGKVKFRGKWRELGTVHRLSPKIAEFANKFAQSFLRSGDNELDVSQKT
LFDNREAVWRNVDPHDWQDELYDAYSSLRDMGVRDSEIAVLVPTNDMGVKVAEFFRSMNVKTDHLFRKNGAGNKRVFVSD
GRMKISTIHSFKGWEARSVIIWIPDRWGQEENLDAVIYTAITRTLENLIILNTNERYLEFYENDEDVEIPDITEDEMDPE
LEEWIETLPYPLASIIWESMTITSYESRVRYLIHFFEALAEFNFNLIMSGLSSDEFFFDMRVRETFGGVKNNLERPTFGY
WTALLFRAIRSLRMVLNDRYHKNQVRKSFGKPDDDFINALANSKLPVILKNVLKYRNVWEGHGPRVSEDEYRKRYSVLIG
ELRNVKDVIGDIYTRNFLVIPSEGILDGGVHRYTAKRYMTTRAPFRAVKLESEKPMDINSIYLANPNKRRHLELLPLIIN
NDDTCYFYNGIDDETGKARYCSYHNKDKAEIFVNPPPKLVNLQEMLNQTDSYN
>Mature_852_residues
SDGRANPSEKVNLSLAEESFITFLQDNLPDDWKIYFKPHLNGSYPDLIIMNPHVGIMIYSILDEVNCTPEAEIRRLGYYK
KKIIRQLVPSMGEMIDKERSAYGIIRTGVYVHGLSSREVKDKFKSGGSYLTCAGHDSLQKSNLEALIPGLRFRKSKYMKP
EWASQLESWMVPSYHREKRTDIRLTEEQERHVKPQPGHRRLRGAAGSGKTLVIAHRAARLAADGHRVLIVTFNSTLWQYI
REMVDRTLYNFDWSLLTFRHFHGFCYDIIHELKIPFDQERVVECLIGSIRDHDISEYMFDAVLIDEGQDFEWEWYNLLSQ
FLTERDELFFVCDERQNIYDRELSWVDKMSGAGKVKFRGKWRELGTVHRLSPKIAEFANKFAQSFLRSGDNELDVSQKTL
FDNREAVWRNVDPHDWQDELYDAYSSLRDMGVRDSEIAVLVPTNDMGVKVAEFFRSMNVKTDHLFRKNGAGNKRVFVSDG
RMKISTIHSFKGWEARSVIIWIPDRWGQEENLDAVIYTAITRTLENLIILNTNERYLEFYENDEDVEIPDITEDEMDPEL
EEWIETLPYPLASIIWESMTITSYESRVRYLIHFFEALAEFNFNLIMSGLSSDEFFFDMRVRETFGGVKNNLERPTFGYW
TALLFRAIRSLRMVLNDRYHKNQVRKSFGKPDDDFINALANSKLPVILKNVLKYRNVWEGHGPRVSEDEYRKRYSVLIGE
LRNVKDVIGDIYTRNFLVIPSEGILDGGVHRYTAKRYMTTRAPFRAVKLESEKPMDINSIYLANPNKRRHLELLPLIINN
DDTCYFYNGIDDETGKARYCSYHNKDKAEIFVNPPPKLVNLQEMLNQTDSYN

Specific function: Unknown

COG id: COG0210

COG function: function code L; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 99811; Mature: 99679

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00024 HEMOPEXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDGRANPSEKVNLSLAEESFITFLQDNLPDDWKIYFKPHLNGSYPDLIIMNPHVGIMIY
CCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEECCCHHHHHH
SILDEVNCTPEAEIRRLGYYKKKIIRQLVPSMGEMIDKERSAYGIIRTGVYVHGLSSREV
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCEEEECCCCHHH
KDKFKSGGSYLTCAGHDSLQKSNLEALIPGLRFRKSKYMKPEWASQLESWMVPSYHREKR
HHHHHCCCCEEEECCCCCHHHCCHHHHCCCHHHHHHCCCCCHHHHHHHHHCCCCHHHCCC
TDIRLTEEQERHVKPQPGHRRLRGAAGSGKTLVIAHRAARLAADGHRVLIVTFNSTLWQY
CCCEECCHHHHCCCCCCCHHHHCCCCCCCCEEEEEEHHHHHHCCCCEEEEEEECHHHHHH
IREMVDRTLYNFDWSLLTFRHFHGFCYDIIHELKIPFDQERVVECLIGSIRDHDISEYMF
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHH
DAVLIDEGQDFEWEWYNLLSQFLTERDELFFVCDERQNIYDRELSWVDKMSGAGKVKFRG
HEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEECC
KWRELGTVHRLSPKIAEFANKFAQSFLRSGDNELDVSQKTLFDNREAVWRNVDPHDWQDE
CHHHHCCHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCHHHHCCCCCCCHHHH
LYDAYSSLRDMGVRDSEIAVLVPTNDMGVKVAEFFRSMNVKTDHLFRKNGAGNKRVFVSD
HHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEEC
GRMKISTIHSFKGWEARSVIIWIPDRWGQEENLDAVIYTAITRTLENLIILNTNERYLEF
CCEEEEEEECCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCEEEECCCHHHHHE
YENDEDVEIPDITEDEMDPELEEWIETLPYPLASIIWESMTITSYESRVRYLIHFFEALA
ECCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHEEHHHHHHHHHHHHHHHHHH
EFNFNLIMSGLSSDEFFFDMRVRETFGGVKNNLERPTFGYWTALLFRAIRSLRMVLNDRY
HCCHHHEEECCCCCCEEEEEHHHHHHCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCHH
HKNQVRKSFGKPDDDFINALANSKLPVILKNVLKYRNVWEGHGPRVSEDEYRKRYSVLIG
HHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
ELRNVKDVIGDIYTRNFLVIPSEGILDGGVHRYTAKRYMTTRAPFRAVKLESEKPMDINS
HHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCE
IYLANPNKRRHLELLPLIINNDDTCYFYNGIDDETGKARYCSYHNKDKAEIFVNPPPKLV
EEEECCCCCCEEEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEECCCCCEE
NLQEMLNQTDSYN
CHHHHHHHCCCCC
>Mature Secondary Structure 
SDGRANPSEKVNLSLAEESFITFLQDNLPDDWKIYFKPHLNGSYPDLIIMNPHVGIMIY
CCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEECCCHHHHHH
SILDEVNCTPEAEIRRLGYYKKKIIRQLVPSMGEMIDKERSAYGIIRTGVYVHGLSSREV
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCEEEECCCCHHH
KDKFKSGGSYLTCAGHDSLQKSNLEALIPGLRFRKSKYMKPEWASQLESWMVPSYHREKR
HHHHHCCCCEEEECCCCCHHHCCHHHHCCCHHHHHHCCCCCHHHHHHHHHCCCCHHHCCC
TDIRLTEEQERHVKPQPGHRRLRGAAGSGKTLVIAHRAARLAADGHRVLIVTFNSTLWQY
CCCEECCHHHHCCCCCCCHHHHCCCCCCCCEEEEEEHHHHHHCCCCEEEEEEECHHHHHH
IREMVDRTLYNFDWSLLTFRHFHGFCYDIIHELKIPFDQERVVECLIGSIRDHDISEYMF
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHH
DAVLIDEGQDFEWEWYNLLSQFLTERDELFFVCDERQNIYDRELSWVDKMSGAGKVKFRG
HEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEECC
KWRELGTVHRLSPKIAEFANKFAQSFLRSGDNELDVSQKTLFDNREAVWRNVDPHDWQDE
CHHHHCCHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCHHHHCCCCCCCHHHH
LYDAYSSLRDMGVRDSEIAVLVPTNDMGVKVAEFFRSMNVKTDHLFRKNGAGNKRVFVSD
HHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEEC
GRMKISTIHSFKGWEARSVIIWIPDRWGQEENLDAVIYTAITRTLENLIILNTNERYLEF
CCEEEEEEECCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCEEEECCCHHHHHE
YENDEDVEIPDITEDEMDPELEEWIETLPYPLASIIWESMTITSYESRVRYLIHFFEALA
ECCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHEEHHHHHHHHHHHHHHHHHH
EFNFNLIMSGLSSDEFFFDMRVRETFGGVKNNLERPTFGYWTALLFRAIRSLRMVLNDRY
HCCHHHEEECCCCCCEEEEEHHHHHHCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCHH
HKNQVRKSFGKPDDDFINALANSKLPVILKNVLKYRNVWEGHGPRVSEDEYRKRYSVLIG
HHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
ELRNVKDVIGDIYTRNFLVIPSEGILDGGVHRYTAKRYMTTRAPFRAVKLESEKPMDINS
HHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCE
IYLANPNKRRHLELLPLIINNDDTCYFYNGIDDETGKARYCSYHNKDKAEIFVNPPPKLV
EEEECCCCCCEEEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEECCCCCEE
NLQEMLNQTDSYN
CHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA