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The map label for this gene is rpl15p

Identifier: 15678056

GI number: 15678056

Start: 12402

End: 12842

Strand: Direct

Name: rpl15p

Synonym: MTH25

Alternate gene names: 15678056

Gene position: 12402-12842 (Clockwise)

Preceding gene: 15678055

Following gene: 15678057

Centisome position: 0.71

GC content: 54.2

Gene sequence:

>441_bases
ATGATCAGAAAAAGACGAAAGATCACAAGGATGAGGGGCTCACGCACCGTCGGTGGAGGATGCTCCAAGAAGAGGAGGGG
AGCAGGTCACCGCGGTGGTAGAGGACAGGCCGGTGGGCACAAACACCACTGGACATGGATAGTCAAGTACGACCCAAAAC
ACTTCGGGAAATACGGCTTCAAGAGGCCCCAGAAACTCATAAAGAGGCTGGAAACAGTTAACCTGGCCTACCTGGATGAA
ATGATACCAGAACTCCTTGAGAGGGGAGTTGCATCCGAGGAGGACGGAATGGTGGTGCTGGATGTCCGCGACCTTGGATT
TGAAAAGGTCCTCGGAAGCGGAAGGATCACAAGGCCCGTCCATCTCAAGGCATACGAGTTCTCCAGGAGCGCCACCGAGA
AGATCGAAGAGGCCGGAGGAAAGGCTGAAGTCATAGAGTGA

Upstream 100 bases:

>100_bases
CGAAGGCATAAAAAAGGCCTTCAATGAGGGCGGAAGCCTTGGATATCGCGGCGAAAAGATAAATGACCTTTTGAAAAGGA
TGATCTAGGAGGAATCACTC

Downstream 100 bases:

>100_bases
AACCAGCTGACAAGGAGTGGAGCAGTTGAAGGAAAAATTTGAACCCCTATTCTCAGTCCTGCCCCAGGTAAAGTCACCTG
GTTACAGGGTTCCCTTCAGG

Product: 50S ribosomal protein L15P

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MIRKRRKITRMRGSRTVGGGCSKKRRGAGHRGGRGQAGGHKHHWTWIVKYDPKHFGKYGFKRPQKLIKRLETVNLAYLDE
MIPELLERGVASEEDGMVVLDVRDLGFEKVLGSGRITRPVHLKAYEFSRSATEKIEEAGGKAEVIE

Sequences:

>Translated_146_residues
MIRKRRKITRMRGSRTVGGGCSKKRRGAGHRGGRGQAGGHKHHWTWIVKYDPKHFGKYGFKRPQKLIKRLETVNLAYLDE
MIPELLERGVASEEDGMVVLDVRDLGFEKVLGSGRITRPVHLKAYEFSRSATEKIEEAGGKAEVIE
>Mature_146_residues
MIRKRRKITRMRGSRTVGGGCSKKRRGAGHRGGRGQAGGHKHHWTWIVKYDPKHFGKYGFKRPQKLIKRLETVNLAYLDE
MIPELLERGVASEEDGMVVLDVRDLGFEKVLGSGRITRPVHLKAYEFSRSATEKIEEAGGKAEVIE

Specific function: Binds to the 23S rRNA

COG id: COG0200

COG function: function code J; Ribosomal protein L15

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribosomal protein L15P family

Homologues:

Organism=Homo sapiens, GI4506625, Length=152, Percent_Identity=38.1578947368421, Blast_Score=73, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17509867, Length=149, Percent_Identity=35.5704697986577, Blast_Score=65, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6321335, Length=150, Percent_Identity=36.6666666666667, Blast_Score=65, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17136880, Length=141, Percent_Identity=36.1702127659575, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RL15_METTH (O26133)

Other databases:

- EMBL:   AE000666
- PIR:   C69131
- RefSeq:   NP_275170.1
- ProteinModelPortal:   O26133
- SMR:   O26133
- STRING:   O26133
- GeneID:   1469987
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH25
- NMPDR:   fig|187420.1.peg.25
- eggNOG:   arNOG11273
- HOGENOM:   HBG727142
- OMA:   GSRTCGG
- PhylomeDB:   O26133
- ProtClustDB:   PRK06419
- BioCyc:   MTHE187420:MTH25-MONOMER
- GO:   GO:0005840
- GO:   GO:0006412
- HAMAP:   MF_01341_A
- InterPro:   IPR001196
- InterPro:   IPR021131

Pfam domain/function: PF00828 Ribosomal_L18e; SSF52080 Ribosomal_L18e/L15

EC number: NA

Molecular weight: Translated: 16540; Mature: 16540

Theoretical pI: Translated: 10.88; Mature: 10.88

Prosite motif: PS00475 RIBOSOMAL_L15

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRKRRKITRMRGSRTVGGGCSKKRRGAGHRGGRGQAGGHKHHWTWIVKYDPKHFGKYGF
CCCHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCEEEEEEEECCHHHCCCCC
KRPQKLIKRLETVNLAYLDEMIPELLERGVASEEDGMVVLDVRDLGFEKVLGSGRITRPV
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHCCHHHHHCCCCCCCCE
HLKAYEFSRSATEKIEEAGGKAEVIE
EEEHHHHHHHHHHHHHHCCCCEECCC
>Mature Secondary Structure
MIRKRRKITRMRGSRTVGGGCSKKRRGAGHRGGRGQAGGHKHHWTWIVKYDPKHFGKYGF
CCCHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCEEEEEEEECCHHHCCCCC
KRPQKLIKRLETVNLAYLDEMIPELLERGVASEEDGMVVLDVRDLGFEKVLGSGRITRPV
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHCCHHHHHCCCCCCCCE
HLKAYEFSRSATEKIEEAGGKAEVIE
EEEHHHHHHHHHHHHHHCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463