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Identifier: 15678046

GI number: 15678046

Start: 7446

End: 8174

Strand: Direct

Name: Not Available

Synonym: MTH15

Alternate gene names: 15678046

Gene position: 7446-8174 (Clockwise)

Preceding gene: 15678045

Following gene: 15678047

Centisome position: 0.43

GC content: 48.83

Gene sequence:

>729_bases
ATGGCAATAATGGCATCAAGAAAACATCTTAAACGATTCAAATCACCGGTTCACTGGCCAATTCATCCCAAGGAATACAA
ATGGACAGTTAAACCATCTCCAGGTCCCCACGCTATTGAGAACTCACTGCCTCTCATGATCATTGTGAGGGACATCCTGA
AGGTTGCAGACAATGCAAGGGAAGCCAGGAAGATAATAAACAGTGGAGAGGTCCTGGTGGATGGAAGACCAAGGAAGAAC
TACAAGTTCCCGGTCGGATTCATGGACGTTGTCAGCATACCCAGGACAGGAGACGTCTACAGGGTGCTCCCTGATGAAAG
GGGAAGGCTGGTTCTCCACCCCATAGATGAGGAAAACGCAGGCTTCAAACTCTGCAAGATAGTGAACAAGACAACCATTA
AGGGAGGCAGGACCCAGCTCAACCTCCATGACGGCCGTAACTACCTCTCAGATGATGAATTCAGGGTGGGAGACGTTGTA
AAGCTCTCAATACCCGAACAGGAAATCCTTGAGAGGATACCATTTGAGAAGGACAGCCTCGGCCTTGTGACAGGCGGACG
GCACACCGGTGAAATAGGCAAGATCAAGAAGATAAACATAACAAGGTCTTCAATGCCAAACACAGCCGTCATCGAGACCG
GTGCAGGCAAGACATTCCTGACACTCAAGGACTACGTTTTCGTCATAGGAAAGGACGAGTCAGTGATCTCACTTCCAGGA
GGGAAATAG

Upstream 100 bases:

>100_bases
CAACAGTCTACTTCCCGCTACACCCATCAAACCTGAGAATAGTTGACCTCAACCTTGACGATGAGAAAAGAATTAAAATC
TTAGAACGGAAGGGATAAAA

Downstream 100 bases:

>100_bases
ATGAACCCGATGGAGGAAGTAAGGATATTCAAGGTCACCCTTAACATAGGTGTTGGTGAAGGCGGTGAAAAGCTTGCAAG
GGCCGAGAGGCTTCTTGAGG

Product: 30S ribosomal protein S4e

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MAIMASRKHLKRFKSPVHWPIHPKEYKWTVKPSPGPHAIENSLPLMIIVRDILKVADNAREARKIINSGEVLVDGRPRKN
YKFPVGFMDVVSIPRTGDVYRVLPDERGRLVLHPIDEENAGFKLCKIVNKTTIKGGRTQLNLHDGRNYLSDDEFRVGDVV
KLSIPEQEILERIPFEKDSLGLVTGGRHTGEIGKIKKINITRSSMPNTAVIETGAGKTFLTLKDYVFVIGKDESVISLPG
GK

Sequences:

>Translated_242_residues
MAIMASRKHLKRFKSPVHWPIHPKEYKWTVKPSPGPHAIENSLPLMIIVRDILKVADNAREARKIINSGEVLVDGRPRKN
YKFPVGFMDVVSIPRTGDVYRVLPDERGRLVLHPIDEENAGFKLCKIVNKTTIKGGRTQLNLHDGRNYLSDDEFRVGDVV
KLSIPEQEILERIPFEKDSLGLVTGGRHTGEIGKIKKINITRSSMPNTAVIETGAGKTFLTLKDYVFVIGKDESVISLPG
GK
>Mature_241_residues
AIMASRKHLKRFKSPVHWPIHPKEYKWTVKPSPGPHAIENSLPLMIIVRDILKVADNAREARKIINSGEVLVDGRPRKNY
KFPVGFMDVVSIPRTGDVYRVLPDERGRLVLHPIDEENAGFKLCKIVNKTTIKGGRTQLNLHDGRNYLSDDEFRVGDVVK
LSIPEQEILERIPFEKDSLGLVTGGRHTGEIGKIKKINITRSSMPNTAVIETGAGKTFLTLKDYVFVIGKDESVISLPGG
K

Specific function: Unknown

COG id: COG1471

COG function: function code J; Ribosomal protein S4E

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain

Homologues:

Organism=Homo sapiens, GI4506725, Length=241, Percent_Identity=35.2697095435685, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI4506727, Length=241, Percent_Identity=34.4398340248963, Blast_Score=135, Evalue=3e-32,
Organism=Homo sapiens, GI88703062, Length=241, Percent_Identity=32.3651452282158, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17543386, Length=240, Percent_Identity=40.8333333333333, Blast_Score=170, Evalue=6e-43,
Organism=Saccharomyces cerevisiae, GI6322605, Length=239, Percent_Identity=37.2384937238494, Blast_Score=142, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6321997, Length=239, Percent_Identity=37.2384937238494, Blast_Score=142, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24663672, Length=241, Percent_Identity=36.0995850622407, Blast_Score=144, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24663668, Length=241, Percent_Identity=36.0995850622407, Blast_Score=144, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RS4E_METTH (O26123)

Other databases:

- EMBL:   AE000666
- PIR:   H69066
- RefSeq:   NP_275160.1
- ProteinModelPortal:   O26123
- STRING:   O26123
- GeneID:   1469977
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH15
- NMPDR:   fig|187420.1.peg.15
- eggNOG:   arNOG06304
- HOGENOM:   HBG392118
- OMA:   QLNLHDG
- PhylomeDB:   O26123
- ProtClustDB:   PRK04313
- BioCyc:   MTHE187420:MTH15-MONOMER
- GO:   GO:0005840
- GO:   GO:0006412
- HAMAP:   MF_00485
- InterPro:   IPR005824
- InterPro:   IPR000876
- InterPro:   IPR022994
- InterPro:   IPR013845
- InterPro:   IPR013843
- InterPro:   IPR018199
- InterPro:   IPR002942
- PANTHER:   PTHR11581
- PIRSF:   PIRSF002116
- ProDom:   PD002667
- SMART:   SM00739
- SMART:   SM00363

Pfam domain/function: PF00900 Ribosomal_S4e; PF08071 RS4NT; PF01479 S4

EC number: NA

Molecular weight: Translated: 27110; Mature: 26979

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: PS00528 RIBOSOMAL_S4E; PS50889 S4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIMASRKHLKRFKSPVHWPIHPKEYKWTVKPSPGPHAIENSLPLMIIVRDILKVADNAR
CCCCCHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCHHHCCCCHHHHHHHHHHHHCCHH
EARKIINSGEVLVDGRPRKNYKFPVGFMDVVSIPRTGDVYRVLPDERGRLVLHPIDEENA
HHHHHHCCCCEEECCCCCCCCCCCCCHHHHHCCCCCCCEEEECCCCCCEEEEEECCCCCC
GFKLCKIVNKTTIKGGRTQLNLHDGRNYLSDDEFRVGDVVKLSIPEQEILERIPFEKDSL
CEEEEEEHHHHCCCCCCEEEEECCCCCCCCCCCEECCCEEEEECCHHHHHHHCCCCCCCE
GLVTGGRHTGEIGKIKKINITRSSMPNTAVIETGAGKTFLTLKDYVFVIGKDESVISLPG
EEEECCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCEEEEEEEEEEEEECCCCEEECCC
GK
CC
>Mature Secondary Structure 
AIMASRKHLKRFKSPVHWPIHPKEYKWTVKPSPGPHAIENSLPLMIIVRDILKVADNAR
CCCCHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCHHHCCCCHHHHHHHHHHHHCCHH
EARKIINSGEVLVDGRPRKNYKFPVGFMDVVSIPRTGDVYRVLPDERGRLVLHPIDEENA
HHHHHHCCCCEEECCCCCCCCCCCCCHHHHHCCCCCCCEEEECCCCCCEEEEEECCCCCC
GFKLCKIVNKTTIKGGRTQLNLHDGRNYLSDDEFRVGDVVKLSIPEQEILERIPFEKDSL
CEEEEEEHHHHCCCCCCEEEEECCCCCCCCCCCEECCCEEEEECCHHHHHHHCCCCCCCE
GLVTGGRHTGEIGKIKKINITRSSMPNTAVIETGAGKTFLTLKDYVFVIGKDESVISLPG
EEEECCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCEEEEEEEEEEEEECCCCEEECCC
GK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463