| Definition | Helicobacter pylori 26695, complete genome. |
|---|---|
| Accession | NC_000915 |
| Length | 1,667,867 |
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Identifier: 15646079
GI number: 15646079
Start: 1540697
End: 1543375
Strand: Reverse
Name: Not Available
Synonym: HP1470
Alternate gene names: 15646079
Gene position: 1543375-1540697 (Counterclockwise)
Preceding gene: 15646080
Following gene: 15646078
Centisome position: 92.54
GC content: 38.75
Gene sequence:
>2679_bases ATGATGGAGCAGCCAGTCATTAAAGAAGGGACTTTAGCTTTAATTGATACTTTTGCGTATTTGTTTAGAAGCTATTACAT GAGCGCTAAAAATAAGCCTTTAACCAACGATAAGGGCTTTCCTACAGGGCTTTTAACGGGGCTTGTGGGCATGGTTAAAA AATTTTATAAAGACAGAAAAAACATGCCTTTTATCGTGTTCGCTTTAGAAAGCCAGACTAAAACTAAAAGAGCCGAAAAA TTAGGCGAATACAAACAAAATCGTAAAGACGCCCCCAAAGAGATGCTTTTACAAATCCCTATCGCCTTAGAATGGTTGCA AAAAATGGGTTTTGTTTGCGTGGAGGTGAATGGGTTTGAAGCTGATGATGTTATCGCAAGCCTAGCCACGCTAAGCCCTT ATAAAACCCGTATTTATTCTAAAGATAAGGATTTTAACCAGCTTTTGAGCGATAAAATCGCGCTTTTTGATGGCAAAACG GAGTTTTTGGCGAAAGATTGCGTGGAAAAATACGGGATTTTGCCGAGTCAATTCACGGATTATCAAGGCATTGTGGGGGA TAGCAGCGATAATTACAAGGGGGTTAAAGGCATTGGGAGCAAGAACGCTAAGGAATTGTTGCAGCGATTAGGGAGCTTGG AAAAAATCTATGAAAATTTAGACTTGGCGAAAAATTTACTCAGCCCTAAAATGTATCGAGCCCTGATACACGACAAAGCA AGCGCGTTTTTAAGCAAAGAATTAGCCACTTTAGAAAGAGGATGCATTAAAGAATTTGATTTTTTAAGTTGCGCTTTTCC TAGCGAAAACCCCTTATTGAAAATTAAAGATGAATTGAAAGAATATGGTTTCATTTCTACTTTAAGGGATTTAGAGAATT CCCCTACGCCTTTAATTTTAGACAACGCCCCCCTATTAGACAACACGCCCGCCTTAGACAACACCCCTAAAAAATCATGC ATGATCGTTTTGGAAAGCGCCGCACCTTTGAGCGCGTTTTTAGAAAAACTAGAAAAAACTAACGCAAGGGTTTTTGCGCG TTTGGTGCTGGATAAAGAAAAAAAAGTTCTGGCCCTAGCGTTTTTATATGAAGATCAAGGCTATTTTTTACCTTTAGAAG AGGCGTTATTTTCGCCCTTTTCTTTAGAGTTTTTGCAAAACGCTTTTTTTAAAATGTTACAGCATGCGCAAATCATTGGG CATGATTTAAAACCCTTGTTGAGCTTTTTAAAAGCCAAATACCAGGTGCCTTTAGAAAACATTCGCATCCAAGACACTCA AATTTTAGCGTTTTTAAAAAATCCGGAAAAAGTGGGGTTTGATGAAGTTTTAAAGGAATATTTAAAAGAAGAATTGATTC CGCATGAAAAAATCAAAGATTTTAAGACTAAAGCGGAGAAATTGGAACTTTTAAGCGTGGAATTAAACGCTTTAAAGCGT TTGTGTGAATATTTTGAAAAGGGGGGATTGGAAGAAAACTTGCTTTCTTTGGCCAGAGAAATTGAAACGCCCTTTATGAA AGTTTTAATGGGCATGGAGTTTCAAGGCTTTAAGATTGATGCGCCTTATTTCAAGCGCTTAGAGCAGGAGTTTAAGAATG AATTGCATGTTTTAGAGCGCCAAATTTTGGAACTAATTGGCGTGGATTTTAACCTCAATTCGCCCAAGCAACTTAGCGAA GTCTTGTATGATAAATTAGGGCTTCCTAAAAACAAAAGCCATTCTACCGATGAAAAAAGCCTGTTAAAAATCCTAGACAA GCATCCAAGCATCGCTTTGATTTTAGAATACAGAGAATTGAACAAGCTTTTTAACACTTATACCACCCCCTTATTGCGCC TAAAAGACAAAGACGATAAAATCCATACCACTTTTATCCAAACCGGCACAGCTACCGGGCGTTTAAGCTCGCATTCGCCT AATTTGCAAAATATCCCAGTGCGATCGCCTAAGGGCTTACTCATTCGTAAAGGCTTTATCGCCAGCTCTAAAGAGTATTG TTTGCTAGGGGTGGATTATTCGCAGATTGAATTGCGCTTATTAGCCCATTTCAGCCAGGATAAGGATTTAATGGAGGCGT TTTTAAAGGGGCGAGACATCCATTTAGAAACTTCTAAGGCGTTGTTTGGAGAATATTTGGCTAAAGAAAAACGATCCATC GCTAAAAGCATTAATTTTGGGCTGGTGTATGGCATGGGGAGTAAGAAATTGAGCGAAACTTTAAACATCTCTTTAAATGA GGCTAAAAGCTACATAGAAGCGTATTTCAAACGATTCCCTAGTATTAAAGATTATTTAAACCGCATGAAAGAAGAGATTT TAAAAACTTCTAAAGCCTTCACTTTGCTTGGGCGTTATCGGGTGTTTGATTTTACCGGCGCAAATGACTATGTTAAGGGC AATTATTTGCGAGAGGGCGTGAATGCGATTTTTCAAGGGAGCGCTAGCGATTTATTGAAATTAGGCATGCTCAAAGTGAG CGAGCGTTTCAAAAATAACCCTTCAGTTAGGCTGCTTTTGCAAGTGCATGACGAATTGATTTTTGAGATTGAAGAAAAAA ACGCCCCAGAGTTGCAGCAAGAAATCCAACGCATTCTCAATGATGAAGTGTATCCTTTGAGGGTGCCGTTAGAAACGAGC GCGTTTATCGCTAAGCGTTGGAATGAATTAAAAGGTTAG
Upstream 100 bases:
>100_bases GAAGCGCCCGTTCAAAAAGACTCGTTATTTTAAAAGGGGTTTTAAGCGCGCTAGCTTGTGTTACAATAAACTTAAAATTC GCTTGATTGAAGAGGGTTGA
Downstream 100 bases:
>100_bases TTTTTTAATTGAGTTTAAGAAAAAATATATTATTATTTCTTTATAAGTAATACTTAGCCATTTTAAGCTAATATAATATA GAGCGATTATCAAAAAATAA
Product: DNA polymerase I (polA)
Products: NA
Alternate protein names: POL I [H]
Number of amino acids: Translated: 892; Mature: 892
Protein sequence:
>892_residues MMEQPVIKEGTLALIDTFAYLFRSYYMSAKNKPLTNDKGFPTGLLTGLVGMVKKFYKDRKNMPFIVFALESQTKTKRAEK LGEYKQNRKDAPKEMLLQIPIALEWLQKMGFVCVEVNGFEADDVIASLATLSPYKTRIYSKDKDFNQLLSDKIALFDGKT EFLAKDCVEKYGILPSQFTDYQGIVGDSSDNYKGVKGIGSKNAKELLQRLGSLEKIYENLDLAKNLLSPKMYRALIHDKA SAFLSKELATLERGCIKEFDFLSCAFPSENPLLKIKDELKEYGFISTLRDLENSPTPLILDNAPLLDNTPALDNTPKKSC MIVLESAAPLSAFLEKLEKTNARVFARLVLDKEKKVLALAFLYEDQGYFLPLEEALFSPFSLEFLQNAFFKMLQHAQIIG HDLKPLLSFLKAKYQVPLENIRIQDTQILAFLKNPEKVGFDEVLKEYLKEELIPHEKIKDFKTKAEKLELLSVELNALKR LCEYFEKGGLEENLLSLAREIETPFMKVLMGMEFQGFKIDAPYFKRLEQEFKNELHVLERQILELIGVDFNLNSPKQLSE VLYDKLGLPKNKSHSTDEKSLLKILDKHPSIALILEYRELNKLFNTYTTPLLRLKDKDDKIHTTFIQTGTATGRLSSHSP NLQNIPVRSPKGLLIRKGFIASSKEYCLLGVDYSQIELRLLAHFSQDKDLMEAFLKGRDIHLETSKALFGEYLAKEKRSI AKSINFGLVYGMGSKKLSETLNISLNEAKSYIEAYFKRFPSIKDYLNRMKEEILKTSKAFTLLGRYRVFDFTGANDYVKG NYLREGVNAIFQGSASDLLKLGMLKVSERFKNNPSVRLLLQVHDELIFEIEEKNAPELQQEIQRILNDEVYPLRVPLETS AFIAKRWNELKG
Sequences:
>Translated_892_residues MMEQPVIKEGTLALIDTFAYLFRSYYMSAKNKPLTNDKGFPTGLLTGLVGMVKKFYKDRKNMPFIVFALESQTKTKRAEK LGEYKQNRKDAPKEMLLQIPIALEWLQKMGFVCVEVNGFEADDVIASLATLSPYKTRIYSKDKDFNQLLSDKIALFDGKT EFLAKDCVEKYGILPSQFTDYQGIVGDSSDNYKGVKGIGSKNAKELLQRLGSLEKIYENLDLAKNLLSPKMYRALIHDKA SAFLSKELATLERGCIKEFDFLSCAFPSENPLLKIKDELKEYGFISTLRDLENSPTPLILDNAPLLDNTPALDNTPKKSC MIVLESAAPLSAFLEKLEKTNARVFARLVLDKEKKVLALAFLYEDQGYFLPLEEALFSPFSLEFLQNAFFKMLQHAQIIG HDLKPLLSFLKAKYQVPLENIRIQDTQILAFLKNPEKVGFDEVLKEYLKEELIPHEKIKDFKTKAEKLELLSVELNALKR LCEYFEKGGLEENLLSLAREIETPFMKVLMGMEFQGFKIDAPYFKRLEQEFKNELHVLERQILELIGVDFNLNSPKQLSE VLYDKLGLPKNKSHSTDEKSLLKILDKHPSIALILEYRELNKLFNTYTTPLLRLKDKDDKIHTTFIQTGTATGRLSSHSP NLQNIPVRSPKGLLIRKGFIASSKEYCLLGVDYSQIELRLLAHFSQDKDLMEAFLKGRDIHLETSKALFGEYLAKEKRSI AKSINFGLVYGMGSKKLSETLNISLNEAKSYIEAYFKRFPSIKDYLNRMKEEILKTSKAFTLLGRYRVFDFTGANDYVKG NYLREGVNAIFQGSASDLLKLGMLKVSERFKNNPSVRLLLQVHDELIFEIEEKNAPELQQEIQRILNDEVYPLRVPLETS AFIAKRWNELKG >Mature_892_residues MMEQPVIKEGTLALIDTFAYLFRSYYMSAKNKPLTNDKGFPTGLLTGLVGMVKKFYKDRKNMPFIVFALESQTKTKRAEK LGEYKQNRKDAPKEMLLQIPIALEWLQKMGFVCVEVNGFEADDVIASLATLSPYKTRIYSKDKDFNQLLSDKIALFDGKT EFLAKDCVEKYGILPSQFTDYQGIVGDSSDNYKGVKGIGSKNAKELLQRLGSLEKIYENLDLAKNLLSPKMYRALIHDKA SAFLSKELATLERGCIKEFDFLSCAFPSENPLLKIKDELKEYGFISTLRDLENSPTPLILDNAPLLDNTPALDNTPKKSC MIVLESAAPLSAFLEKLEKTNARVFARLVLDKEKKVLALAFLYEDQGYFLPLEEALFSPFSLEFLQNAFFKMLQHAQIIG HDLKPLLSFLKAKYQVPLENIRIQDTQILAFLKNPEKVGFDEVLKEYLKEELIPHEKIKDFKTKAEKLELLSVELNALKR LCEYFEKGGLEENLLSLAREIETPFMKVLMGMEFQGFKIDAPYFKRLEQEFKNELHVLERQILELIGVDFNLNSPKQLSE VLYDKLGLPKNKSHSTDEKSLLKILDKHPSIALILEYRELNKLFNTYTTPLLRLKDKDDKIHTTFIQTGTATGRLSSHSP NLQNIPVRSPKGLLIRKGFIASSKEYCLLGVDYSQIELRLLAHFSQDKDLMEAFLKGRDIHLETSKALFGEYLAKEKRSI AKSINFGLVYGMGSKKLSETLNISLNEAKSYIEAYFKRFPSIKDYLNRMKEEILKTSKAFTLLGRYRVFDFTGANDYVKG NYLREGVNAIFQGSASDLLKLGMLKVSERFKNNPSVRLLLQVHDELIFEIEEKNAPELQQEIQRILNDEVYPLRVPLETS AFIAKRWNELKG
Specific function: In addition to polymerase activity, this DNA polymerase exhibits 3' to 5' and 5' to 3' exonuclease activity [H]
COG id: COG0749
COG function: function code L; DNA polymerase I - 3'-5' exonuclease and polymerase domains
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 5'-3' exonuclease domain [H]
Homologues:
Organism=Homo sapiens, GI112420958, Length=450, Percent_Identity=30.2222222222222, Blast_Score=191, Evalue=3e-48, Organism=Homo sapiens, GI139394648, Length=537, Percent_Identity=25.1396648044693, Blast_Score=153, Evalue=8e-37, Organism=Escherichia coli, GI1790294, Length=945, Percent_Identity=32.3809523809524, Blast_Score=377, Evalue=1e-105, Organism=Escherichia coli, GI226510970, Length=192, Percent_Identity=35.4166666666667, Blast_Score=103, Evalue=7e-23, Organism=Caenorhabditis elegans, GI86563272, Length=441, Percent_Identity=30.3854875283447, Blast_Score=194, Evalue=2e-49, Organism=Drosophila melanogaster, GI17933644, Length=441, Percent_Identity=31.5192743764172, Blast_Score=183, Evalue=4e-46,
Paralogues:
None
Copy number: 400 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002562 - InterPro: IPR020046 - InterPro: IPR020045 - InterPro: IPR002421 - InterPro: IPR020047 - InterPro: IPR019760 - InterPro: IPR001098 - InterPro: IPR018320 - InterPro: IPR002298 - InterPro: IPR008918 - InterPro: IPR012337 [H]
Pfam domain/function: PF01367 5_3_exonuc; PF02739 5_3_exonuc_N; PF00476 DNA_pol_A [H]
EC number: =2.7.7.7 [H]
Molecular weight: Translated: 102108; Mature: 102108
Theoretical pI: Translated: 8.72; Mature: 8.72
Prosite motif: PS00447 DNA_POLYMERASE_A
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MMEQPVIKEGTLALIDTFAYLFRSYYMSAKNKPLTNDKGFPTGLLTGLVGMVKKFYKDRK CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC NMPFIVFALESQTKTKRAEKLGEYKQNRKDAPKEMLLQIPIALEWLQKMGFVCVEVNGFE CCCEEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCC ADDVIASLATLSPYKTRIYSKDKDFNQLLSDKIALFDGKTEFLAKDCVEKYGILPSQFTD HHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCC YQGIVGDSSDNYKGVKGIGSKNAKELLQRLGSLEKIYENLDLAKNLLSPKMYRALIHDKA CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH SAFLSKELATLERGCIKEFDFLSCAFPSENPLLKIKDELKEYGFISTLRDLENSPTPLIL HHHHHHHHHHHHHHHHHHCCCCEECCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCEEE DNAPLLDNTPALDNTPKKSCMIVLESAAPLSAFLEKLEKTNARVFARLVLDKEKKVLALA CCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE FLYEDQGYFLPLEEALFSPFSLEFLQNAFFKMLQHAQIIGHDLKPLLSFLKAKYQVPLEN EEEECCCCEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHH IRIQDTQILAFLKNPEKVGFDEVLKEYLKEELIPHEKIKDFKTKAEKLELLSVELNALKR CEECHHHHEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH LCEYFEKGGLEENLLSLAREIETPFMKVLMGMEFQGFKIDAPYFKRLEQEFKNELHVLER HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHH QILELIGVDFNLNSPKQLSEVLYDKLGLPKNKSHSTDEKSLLKILDKHPSIALILEYREL HHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEHHHH NKLFNTYTTPLLRLKDKDDKIHTTFIQTGTATGRLSSHSPNLQNIPVRSPKGLLIRKGFI HHHHHHHCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCC ASSKEYCLLGVDYSQIELRLLAHFSQDKDLMEAFLKGRDIHLETSKALFGEYLAKEKRSI CCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHH AKSINFGLVYGMGSKKLSETLNISLNEAKSYIEAYFKRFPSIKDYLNRMKEEILKTSKAF HHHCCCEEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH TLLGRYRVFDFTGANDYVKGNYLREGVNAIFQGSASDLLKLGMLKVSERFKNNPSVRLLL HHHHCEEEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEHH QVHDELIFEIEEKNAPELQQEIQRILNDEVYPLRVPLETSAFIAKRWNELKG HHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCC >Mature Secondary Structure MMEQPVIKEGTLALIDTFAYLFRSYYMSAKNKPLTNDKGFPTGLLTGLVGMVKKFYKDRK CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC NMPFIVFALESQTKTKRAEKLGEYKQNRKDAPKEMLLQIPIALEWLQKMGFVCVEVNGFE CCCEEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCC ADDVIASLATLSPYKTRIYSKDKDFNQLLSDKIALFDGKTEFLAKDCVEKYGILPSQFTD HHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCC YQGIVGDSSDNYKGVKGIGSKNAKELLQRLGSLEKIYENLDLAKNLLSPKMYRALIHDKA CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH SAFLSKELATLERGCIKEFDFLSCAFPSENPLLKIKDELKEYGFISTLRDLENSPTPLIL HHHHHHHHHHHHHHHHHHCCCCEECCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCEEE DNAPLLDNTPALDNTPKKSCMIVLESAAPLSAFLEKLEKTNARVFARLVLDKEKKVLALA CCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE FLYEDQGYFLPLEEALFSPFSLEFLQNAFFKMLQHAQIIGHDLKPLLSFLKAKYQVPLEN EEEECCCCEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHH IRIQDTQILAFLKNPEKVGFDEVLKEYLKEELIPHEKIKDFKTKAEKLELLSVELNALKR CEECHHHHEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH LCEYFEKGGLEENLLSLAREIETPFMKVLMGMEFQGFKIDAPYFKRLEQEFKNELHVLER HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHH QILELIGVDFNLNSPKQLSEVLYDKLGLPKNKSHSTDEKSLLKILDKHPSIALILEYREL HHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEHHHH NKLFNTYTTPLLRLKDKDDKIHTTFIQTGTATGRLSSHSPNLQNIPVRSPKGLLIRKGFI HHHHHHHCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCC ASSKEYCLLGVDYSQIELRLLAHFSQDKDLMEAFLKGRDIHLETSKALFGEYLAKEKRSI CCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHH AKSINFGLVYGMGSKKLSETLNISLNEAKSYIEAYFKRFPSIKDYLNRMKEEILKTSKAF HHHCCCEEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH TLLGRYRVFDFTGANDYVKGNYLREGVNAIFQGSASDLLKLGMLKVSERFKNNPSVRLLL HHHHCEEEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEHH QVHDELIFEIEEKNAPELQQEIQRILNDEVYPLRVPLETSAFIAKRWNELKG HHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9923682 [H]