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Identifier: 15646044

GI number: 15646044

Start: 1507001

End: 1507879

Strand: Reverse

Name: Not Available

Synonym: HP1435

Alternate gene names: 15646044

Gene position: 1507879-1507001 (Counterclockwise)

Preceding gene: 15646049

Following gene: 15646043

Centisome position: 90.41

GC content: 41.41

Gene sequence:

>879_bases
ATGTGGAGTTTCATTCAAAAAATCTTTAAGGCTTTAATCATCGCACCTTTAGATTTTATCACGAAGTATTTCAAGTCGTT
TGTGCTGTTACTCATTGTATTAGTCTTTTTTAGCGCTAAAGAAAGCGCGCCAAGCGCCCCGCCTAATCTCGCTAAACTCT
ATTTAAATGGGGCGATTTTTAGCACCGAGGATTTTGACAAAGAAGTGGATAAAATCCTAAAAACCCCTAGCATTAAGGGC
GTTTTGCTTTTGATTGACTCTCCTGGTGGGGCGGTGTCAGCGAGCGTGGAATTGAGCGAAAAAATCGCTGATTTGAAGCA
AAAAATGCCCGTTTTAGCGTATGCTAGGGGGGTTATGGCGAGCGGGAGCTATTATGCGGGCATGCAAGCGAGCGAAGTTT
ATGCCTCTAAAGCGAGTTTGATAGGATCCATTGGGGTGATTTTTTCAGGTGCGAATGTGGAAAATTTGCTCAATAAAGTC
GGCGTAGCCACTCAAGGCGTGCATGCGGGCGAATACAAAGAAATAGGCACTTTCACCAGAGCGTGGAAACCCAACGAAAA
AGATTTTTTGCAAAATTTAGTCAATGAGCAATACCAAATGTTTGTGAATGATGTCGCAAAAGCTAGGAAATTAGACGCTA
AGGATTATAAGGATTTTGCTGAAGGGAAGGTCTTTAGCGCTCAAAAGGCTCTGAAATTAAAACTCATTGATAAAATCAGC
ACGATTAAGCAAGCGCAAGATCGCTTAATGGAATTGAGTAAGGTTAAAAAAGCTTATTGGCTAGAAAAAAGCCCTATGGA
GCGCTTCATTGAAAAAGCCACGCAATCAGCCACAAACATCATCACACAAGCCTTTGGCTATCAATTATTAATGAGATAA

Upstream 100 bases:

>100_bases
TCTGATCTTGGGGCAAAATTTACACGCCATGATTTAATCCTTAAAACATTTGAAGTATAATACACTCTTATGGTCAAATA
TTAAGTTTAGGAAAAGCTGC

Downstream 100 bases:

>100_bases
AGATGTTAGAATTTATTTTAAAAATTCAAGCTAGAGACTCTAAAGGCTTGGTGAGCACGATTAGCACCACTATCGCTAAC
AAGGGCTATAACATCGTCAA

Product: protease IV (PspA)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MWSFIQKIFKALIIAPLDFITKYFKSFVLLLIVLVFFSAKESAPSAPPNLAKLYLNGAIFSTEDFDKEVDKILKTPSIKG
VLLLIDSPGGAVSASVELSEKIADLKQKMPVLAYARGVMASGSYYAGMQASEVYASKASLIGSIGVIFSGANVENLLNKV
GVATQGVHAGEYKEIGTFTRAWKPNEKDFLQNLVNEQYQMFVNDVAKARKLDAKDYKDFAEGKVFSAQKALKLKLIDKIS
TIKQAQDRLMELSKVKKAYWLEKSPMERFIEKATQSATNIITQAFGYQLLMR

Sequences:

>Translated_292_residues
MWSFIQKIFKALIIAPLDFITKYFKSFVLLLIVLVFFSAKESAPSAPPNLAKLYLNGAIFSTEDFDKEVDKILKTPSIKG
VLLLIDSPGGAVSASVELSEKIADLKQKMPVLAYARGVMASGSYYAGMQASEVYASKASLIGSIGVIFSGANVENLLNKV
GVATQGVHAGEYKEIGTFTRAWKPNEKDFLQNLVNEQYQMFVNDVAKARKLDAKDYKDFAEGKVFSAQKALKLKLIDKIS
TIKQAQDRLMELSKVKKAYWLEKSPMERFIEKATQSATNIITQAFGYQLLMR
>Mature_292_residues
MWSFIQKIFKALIIAPLDFITKYFKSFVLLLIVLVFFSAKESAPSAPPNLAKLYLNGAIFSTEDFDKEVDKILKTPSIKG
VLLLIDSPGGAVSASVELSEKIADLKQKMPVLAYARGVMASGSYYAGMQASEVYASKASLIGSIGVIFSGANVENLLNKV
GVATQGVHAGEYKEIGTFTRAWKPNEKDFLQNLVNEQYQMFVNDVAKARKLDAKDYKDFAEGKVFSAQKALKLKLIDKIS
TIKQAQDRLMELSKVKKAYWLEKSPMERFIEKATQSATNIITQAFGYQLLMR

Specific function: Digestion Of The Cleaved Signal Peptides. This Activity Is Necessary To Maintain Proper Secretion Of Mature Proteins Across The Membrane. [C]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1788064, Length=237, Percent_Identity=29.535864978903, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787527, Length=247, Percent_Identity=24.6963562753036, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 32425; Mature: 32425

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWSFIQKIFKALIIAPLDFITKYFKSFVLLLIVLVFFSAKESAPSAPPNLAKLYLNGAIF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCEE
STEDFDKEVDKILKTPSIKGVLLLIDSPGGAVSASVELSEKIADLKQKMPVLAYARGVMA
CCHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHC
SGSYYAGMQASEVYASKASLIGSIGVIFSGANVENLLNKVGVATQGVHAGEYKEIGTFTR
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHCCCCCCCHHHHHHHHH
AWKPNEKDFLQNLVNEQYQMFVNDVAKARKLDAKDYKDFAEGKVFSAQKALKLKLIDKIS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHH
TIKQAQDRLMELSKVKKAYWLEKSPMERFIEKATQSATNIITQAFGYQLLMR
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MWSFIQKIFKALIIAPLDFITKYFKSFVLLLIVLVFFSAKESAPSAPPNLAKLYLNGAIF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCEE
STEDFDKEVDKILKTPSIKGVLLLIDSPGGAVSASVELSEKIADLKQKMPVLAYARGVMA
CCHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHC
SGSYYAGMQASEVYASKASLIGSIGVIFSGANVENLLNKVGVATQGVHAGEYKEIGTFTR
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHCCCCCCCHHHHHHHHH
AWKPNEKDFLQNLVNEQYQMFVNDVAKARKLDAKDYKDFAEGKVFSAQKALKLKLIDKIS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHH
TIKQAQDRLMELSKVKKAYWLEKSPMERFIEKATQSATNIITQAFGYQLLMR
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]