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Identifier: 15645746

GI number: 15645746

Start: 1194273

End: 1195682

Strand: Reverse

Name: Not Available

Synonym: HP1132

Alternate gene names: 15645746

Gene position: 1195682-1194273 (Counterclockwise)

Preceding gene: 15645747

Following gene: 15645745

Centisome position: 71.69

GC content: 45.11

Gene sequence:

>1410_bases
ATGAAAGCGATGGAAGGTAAAATCATTCAGGTTTTAGGCCCTGTGGTAGATGTGGAGTTTGAATCCTATCTGCCGGCGAT
TTTTGAAGCGTTAGACATTAATTTTGAAGTCAATGGTGTTCAAAAGTCTTTAGTTTTAGAGGTGGCAGCCCATTTGGGCG
GTAATCGGGTGCGAGCGATTGCTATGGATATGACAGAAGGCTTAGTGCGTAACCAAGTGATCAAGGCTCGCGGCAAAATG
ATTGAAGTGCCTGTGGGCGAAGAAGTATTAGGGCGTATTTTTAATGTTGTGGGCGAGAGCATTGACAATTTAGAGCCGCT
TAAGCCGTCCTTAACTTGGCCCATTCACAGAAAAGCCCCTAGTTTTGAGCAGCAAAGCACTAAAACAGAAATGTTTGAAA
CTGGTATTAAAGTCATTGACTTACTCGCGCCTTATTCTAAGGGCGGTAAAGTAGGCTTGTTTGGTGGGGCTGGCGTAGGC
AAAACGGTGATCATTATGGAGCTTATCCATAATGTGGCTTATAAGCATAACGGGTATTCGGTGTTTGCAGGTGTGGGGGA
GCGCACCAGAGAGGGGAATGATCTGTATTTTGAAATGAAAGAAGGGGGCGTTTTAGACAAAGTCGCACTGTGTTATGGGC
AAATGAATGAGCCACCAGGCGCGAGGAACCGCATCGCATTCACCGGCTTGACGATGGCGGAGTATTTTCGTGATGAAAAG
GGCTTAGATGTGTTGATGTTTATTGACAACATCTTTAGATACGCTCAAAGCGGTGCGGAAATGAGCGCGCTATTAGGCCG
TATCCCTTCAGCGGTGGGGTATCAGCCCACGCTAGCCGGGGAAATGGGGAAACTTCAAGAGCGTATCGCTTCCACTAAAA
ATGGCTCTATCACTTCCGTTCAAGCGGTGTATGTGCCAGCAGATGACTTGACTGACCCAGCCCCTGCTTCGGTGTTTGCG
CATTTGGATGCGACTACGGTGTTGAATAGAAAGATCGCTGAAAAAGGGATTTATCCGGCGGTGGATCCTTTGGATTCCAC
TTCAAGGATTTTAAGCCCTCAAATGATCGGTGAGAAACACTATGAAGTCGCTACCGGTATCCAGCAGGTTTTACAAAAAT
ACAAGGATTTGCAAGACATTATTGCGATTTTGGGATTAGACGAATTGAGCGAAGAGGATAAAAAAACGGTTGAAAGGGCC
AGAAAAATTGAGAAGTTTTTATCCCAGCCGTTCTTTGTGGCTGAAGTGTTTACAGGAAGTCCTGGTAAATATGTAACCCT
TCAAGAGACTTTAGAGGGCTTTGGAGGGATTTTAGAGGGCAAATACGATCATATTCCCGAGAACGCGTTTTATATGGTGG
GTAGCATTCAAGAGGTTTTAGAAAAAGCTAAAAACATGAAAAATTCCTAA

Upstream 100 bases:

>100_bases
TCTTATAATAAAGCCAGACAAGAGGCGATTACGACTGAGCTAGTAGAAATCAATGCTGGCGTAGAAGCCCTAAAATAAAA
ATTATATTAATCAAGGAGCG

Downstream 100 bases:

>100_bases
GGGTTTTGTGATGGCTTTGTTGAAAATTAGTGTGGTAGTTCCTGAGGGGGAAGTCTATACAGGAGAGGTTAAAAGCGTTG
TGTTGCCAGGAGTTGAAGGG

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta [H]

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MKAMEGKIIQVLGPVVDVEFESYLPAIFEALDINFEVNGVQKSLVLEVAAHLGGNRVRAIAMDMTEGLVRNQVIKARGKM
IEVPVGEEVLGRIFNVVGESIDNLEPLKPSLTWPIHRKAPSFEQQSTKTEMFETGIKVIDLLAPYSKGGKVGLFGGAGVG
KTVIIMELIHNVAYKHNGYSVFAGVGERTREGNDLYFEMKEGGVLDKVALCYGQMNEPPGARNRIAFTGLTMAEYFRDEK
GLDVLMFIDNIFRYAQSGAEMSALLGRIPSAVGYQPTLAGEMGKLQERIASTKNGSITSVQAVYVPADDLTDPAPASVFA
HLDATTVLNRKIAEKGIYPAVDPLDSTSRILSPQMIGEKHYEVATGIQQVLQKYKDLQDIIAILGLDELSEEDKKTVERA
RKIEKFLSQPFFVAEVFTGSPGKYVTLQETLEGFGGILEGKYDHIPENAFYMVGSIQEVLEKAKNMKNS

Sequences:

>Translated_469_residues
MKAMEGKIIQVLGPVVDVEFESYLPAIFEALDINFEVNGVQKSLVLEVAAHLGGNRVRAIAMDMTEGLVRNQVIKARGKM
IEVPVGEEVLGRIFNVVGESIDNLEPLKPSLTWPIHRKAPSFEQQSTKTEMFETGIKVIDLLAPYSKGGKVGLFGGAGVG
KTVIIMELIHNVAYKHNGYSVFAGVGERTREGNDLYFEMKEGGVLDKVALCYGQMNEPPGARNRIAFTGLTMAEYFRDEK
GLDVLMFIDNIFRYAQSGAEMSALLGRIPSAVGYQPTLAGEMGKLQERIASTKNGSITSVQAVYVPADDLTDPAPASVFA
HLDATTVLNRKIAEKGIYPAVDPLDSTSRILSPQMIGEKHYEVATGIQQVLQKYKDLQDIIAILGLDELSEEDKKTVERA
RKIEKFLSQPFFVAEVFTGSPGKYVTLQETLEGFGGILEGKYDHIPENAFYMVGSIQEVLEKAKNMKNS
>Mature_469_residues
MKAMEGKIIQVLGPVVDVEFESYLPAIFEALDINFEVNGVQKSLVLEVAAHLGGNRVRAIAMDMTEGLVRNQVIKARGKM
IEVPVGEEVLGRIFNVVGESIDNLEPLKPSLTWPIHRKAPSFEQQSTKTEMFETGIKVIDLLAPYSKGGKVGLFGGAGVG
KTVIIMELIHNVAYKHNGYSVFAGVGERTREGNDLYFEMKEGGVLDKVALCYGQMNEPPGARNRIAFTGLTMAEYFRDEK
GLDVLMFIDNIFRYAQSGAEMSALLGRIPSAVGYQPTLAGEMGKLQERIASTKNGSITSVQAVYVPADDLTDPAPASVFA
HLDATTVLNRKIAEKGIYPAVDPLDSTSRILSPQMIGEKHYEVATGIQQVLQKYKDLQDIIAILGLDELSEEDKKTVERA
RKIEKFLSQPFFVAEVFTGSPGKYVTLQETLEGFGGILEGKYDHIPENAFYMVGSIQEVLEKAKNMKNS

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits [H]

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=470, Percent_Identity=67.6595744680851, Blast_Score=642, Evalue=0.0,
Organism=Homo sapiens, GI19913424, Length=319, Percent_Identity=29.4670846394984, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI19913426, Length=434, Percent_Identity=25.3456221198157, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI19913428, Length=432, Percent_Identity=24.7685185185185, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI50345984, Length=348, Percent_Identity=25.5747126436782, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI4757810, Length=348, Percent_Identity=25.5747126436782, Blast_Score=111, Evalue=2e-24,
Organism=Escherichia coli, GI1790170, Length=462, Percent_Identity=66.4502164502164, Blast_Score=623, Evalue=1e-180,
Organism=Escherichia coli, GI1788251, Length=387, Percent_Identity=27.6485788113695, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1790172, Length=388, Percent_Identity=24.4845360824742, Blast_Score=115, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI25144756, Length=467, Percent_Identity=66.1670235546039, Blast_Score=630, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17565854, Length=319, Percent_Identity=30.7210031347962, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17570191, Length=422, Percent_Identity=25.1184834123223, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17510931, Length=348, Percent_Identity=26.7241379310345, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71988080, Length=352, Percent_Identity=24.7159090909091, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71988063, Length=352, Percent_Identity=24.7159090909091, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71988074, Length=329, Percent_Identity=24.0121580547112, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322581, Length=463, Percent_Identity=67.8185745140389, Blast_Score=634, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=421, Percent_Identity=27.0783847980998, Blast_Score=129, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6319370, Length=401, Percent_Identity=24.4389027431421, Blast_Score=109, Evalue=9e-25,
Organism=Saccharomyces cerevisiae, GI6320016, Length=260, Percent_Identity=26.1538461538462, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24638766, Length=467, Percent_Identity=68.7366167023555, Blast_Score=644, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574560, Length=474, Percent_Identity=63.5021097046413, Blast_Score=593, Evalue=1e-170,
Organism=Drosophila melanogaster, GI24583992, Length=394, Percent_Identity=27.9187817258883, Blast_Score=136, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24583988, Length=394, Percent_Identity=27.6649746192893, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24583986, Length=394, Percent_Identity=27.6649746192893, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24583984, Length=394, Percent_Identity=27.6649746192893, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI20129479, Length=335, Percent_Identity=28.6567164179104, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI281361666, Length=419, Percent_Identity=25.5369928400955, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24646341, Length=419, Percent_Identity=25.5369928400955, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17136796, Length=419, Percent_Identity=25.5369928400955, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24658560, Length=428, Percent_Identity=23.3644859813084, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24638768, Length=95, Percent_Identity=55.7894736842105, Blast_Score=95, Evalue=1e-19,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 51479; Mature: 51479

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAMEGKIIQVLGPVVDVEFESYLPAIFEALDINFEVNGVQKSLVLEVAAHLGGNRVRAI
CCCCCCHHHHHHCCHHCCCHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHCCCCEEEEE
AMDMTEGLVRNQVIKARGKMIEVPVGEEVLGRIFNVVGESIDNLEPLKPSLTWPIHRKAP
EHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
SFEQQSTKTEMFETGIKVIDLLAPYSKGGKVGLFGGAGVGKTVIIMELIHNVAYKHNGYS
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCEE
VFAGVGERTREGNDLYFEMKEGGVLDKVALCYGQMNEPPGARNRIAFTGLTMAEYFRDEK
EEECCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHCCCC
GLDVLMFIDNIFRYAQSGAEMSALLGRIPSAVGYQPTLAGEMGKLQERIASTKNGSITSV
CCEEHHHHHHHHHHHHCCHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEE
QAVYVPADDLTDPAPASVFAHLDATTVLNRKIAEKGIYPAVDPLDSTSRILSPQMIGEKH
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHHCCHH
YEVATGIQQVLQKYKDLQDIIAILGLDELSEEDKKTVERARKIEKFLSQPFFVAEVFTGS
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHCHHHHHHHHHHHHHHHHHCCCEEEEEEEECC
PGKYVTLQETLEGFGGILEGKYDHIPENAFYMVGSIQEVLEKAKNMKNS
CCCEEEHHHHHHHHCCCCCCCHHCCCCCCEEHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKAMEGKIIQVLGPVVDVEFESYLPAIFEALDINFEVNGVQKSLVLEVAAHLGGNRVRAI
CCCCCCHHHHHHCCHHCCCHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHCCCCEEEEE
AMDMTEGLVRNQVIKARGKMIEVPVGEEVLGRIFNVVGESIDNLEPLKPSLTWPIHRKAP
EHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
SFEQQSTKTEMFETGIKVIDLLAPYSKGGKVGLFGGAGVGKTVIIMELIHNVAYKHNGYS
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCEE
VFAGVGERTREGNDLYFEMKEGGVLDKVALCYGQMNEPPGARNRIAFTGLTMAEYFRDEK
EEECCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHCCCC
GLDVLMFIDNIFRYAQSGAEMSALLGRIPSAVGYQPTLAGEMGKLQERIASTKNGSITSV
CCEEHHHHHHHHHHHHCCHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEE
QAVYVPADDLTDPAPASVFAHLDATTVLNRKIAEKGIYPAVDPLDSTSRILSPQMIGEKH
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHHCCHH
YEVATGIQQVLQKYKDLQDIIAILGLDELSEEDKKTVERARKIEKFLSQPFFVAEVFTGS
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHCHHHHHHHHHHHHHHHHHCCCEEEEEEEECC
PGKYVTLQETLEGFGGILEGKYDHIPENAFYMVGSIQEVLEKAKNMKNS
CCCEEEHHHHHHHHCCCCCCCHHCCCCCCEEHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA