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The map label for this gene is glyQ

Identifier: 15645576

GI number: 15645576

Start: 1018460

End: 1019371

Strand: Reverse

Name: glyQ

Synonym: HP0960

Alternate gene names: 15645576

Gene position: 1019371-1018460 (Counterclockwise)

Preceding gene: 15645577

Following gene: 15645575

Centisome position: 61.12

GC content: 42.0

Gene sequence:

>912_bases
ATGCAAGATTTTTCAAGTTTATTATTAAAACTACAAGAGTATTGGAAGAATCAAGGCTGTTTGGTGATCCAGCCTTATGA
TATTCCTGCAGGAGCTGGGACATTCCATCCGGCCACGCTTTTAAGGAGTTTGGATAAAAAGCCGTGGAATGTGGCGTATG
TCGCGCCCTCTAGAAGGCCTACTGATGGGCGCTATGGGGAAAACCCTAACCGCTTGGGGAGTTATTACCAATTCCAAGTA
GTCATCAAGCCCAGCCCTTCTAATATCCAGGAACTCTATTTAAAAAGCTTAGAAGTGTTAGGGATAAACCTTAATGAGCA
TGATATACGATTTGTAGAAGACAATTGGGAGAGTCCGACTTTAGGGGCATGGGGGCTTGGCTGGGAAGTGTGGCTTGATG
GCATGGAAGTTACGCAATTCACTTATTTCCAGCAAGTGGGGGGCATTGCTTGTAGCCCTATTCCTGTAGAGATCACTTAC
GGCTTAGAAAGATTAGCGATGTATGTGCAAAAAGTGGAAAATATCCTAGAGATTGAATGGGCTAAAAAAAATCATGACAG
CGTGAATTACGCACAAGTGCATTTGGAAAGCGAATACGAATTCAGCAAGTATCATTTTGAAACAGCGAGCGTGAAACGGC
TATTAGAAATGTTTAAAAACGCTCAAGCCGAAGCCTTGCATTGCTTGGAAAACAAGCTCCCCTTGCCGGCTTATGATTTT
GTGATGTTATGCTCGCATTTTTTCAATATTTTAGACGCCAGAAAAGCGATTTCGGTGGCTGAAAGGCAAAATTATATTTT
ACAAATCAGGGATTTAGCCAAAGGGTGTGCGCTTCTTTATAAAGAACAAGAAGAAGAGAGGGAAGAGCGTTTAAAAAACG
CTTTAACAAAGGCTGAAAATGGCGTTAGTTAA

Upstream 100 bases:

>100_bases
TATACGCCCATTGCGAGCGAATTAGCCTTGCTTTTAAAGGGTAAGAGTGTGCTAGAGAGCATGAACGATTTGATCAGACG
CGCTTAAAAGGAAAGAGAGC

Downstream 100 bases:

>100_bases
GGAAGTGTTGGTAGTTTTGAATCGCCTTTCGCCTTTTGAACTCCAAGAATCATGGGATAATAGCGGGTTGAATGTGGGGA
GTGAAAATAGTGAATTTAGC

Product: glycyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Glycine--tRNA ligase alpha subunit; GlyRS

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MQDFSSLLLKLQEYWKNQGCLVIQPYDIPAGAGTFHPATLLRSLDKKPWNVAYVAPSRRPTDGRYGENPNRLGSYYQFQV
VIKPSPSNIQELYLKSLEVLGINLNEHDIRFVEDNWESPTLGAWGLGWEVWLDGMEVTQFTYFQQVGGIACSPIPVEITY
GLERLAMYVQKVENILEIEWAKKNHDSVNYAQVHLESEYEFSKYHFETASVKRLLEMFKNAQAEALHCLENKLPLPAYDF
VMLCSHFFNILDARKAISVAERQNYILQIRDLAKGCALLYKEQEEEREERLKNALTKAENGVS

Sequences:

>Translated_303_residues
MQDFSSLLLKLQEYWKNQGCLVIQPYDIPAGAGTFHPATLLRSLDKKPWNVAYVAPSRRPTDGRYGENPNRLGSYYQFQV
VIKPSPSNIQELYLKSLEVLGINLNEHDIRFVEDNWESPTLGAWGLGWEVWLDGMEVTQFTYFQQVGGIACSPIPVEITY
GLERLAMYVQKVENILEIEWAKKNHDSVNYAQVHLESEYEFSKYHFETASVKRLLEMFKNAQAEALHCLENKLPLPAYDF
VMLCSHFFNILDARKAISVAERQNYILQIRDLAKGCALLYKEQEEEREERLKNALTKAENGVS
>Mature_303_residues
MQDFSSLLLKLQEYWKNQGCLVIQPYDIPAGAGTFHPATLLRSLDKKPWNVAYVAPSRRPTDGRYGENPNRLGSYYQFQV
VIKPSPSNIQELYLKSLEVLGINLNEHDIRFVEDNWESPTLGAWGLGWEVWLDGMEVTQFTYFQQVGGIACSPIPVEITY
GLERLAMYVQKVENILEIEWAKKNHDSVNYAQVHLESEYEFSKYHFETASVKRLLEMFKNAQAEALHCLENKLPLPAYDF
VMLCSHFFNILDARKAISVAERQNYILQIRDLAKGCALLYKEQEEEREERLKNALTKAENGVS

Specific function: Unknown

COG id: COG0752

COG function: function code J; Glycyl-tRNA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Escherichia coli, GI1789983, Length=284, Percent_Identity=60.9154929577465, Blast_Score=356, Evalue=1e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYGA_HELPY (P56453)

Other databases:

- EMBL:   AE000511
- PIR:   H64639
- RefSeq:   NP_207752.1
- ProteinModelPortal:   P56453
- SMR:   P56453
- GeneID:   899493
- GenomeReviews:   AE000511_GR
- KEGG:   hpy:HP0960
- NMPDR:   fig|85962.1.peg.949
- TIGR:   HP_0960
- HOGENOM:   HBG285316
- OMA:   CRRPTDG
- ProtClustDB:   PRK09348
- BRENDA:   6.1.1.14
- GO:   GO:0005737
- HAMAP:   MF_00254
- InterPro:   IPR006194
- InterPro:   IPR002310
- PRINTS:   PR01044
- TIGRFAMs:   TIGR00388

Pfam domain/function: PF02091 tRNA-synt_2e

EC number: =6.1.1.14

Molecular weight: Translated: 34936; Mature: 34936

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS50861 AA_TRNA_LIGASE_II_GLYAB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDFSSLLLKLQEYWKNQGCLVIQPYDIPAGAGTFHPATLLRSLDKKPWNVAYVAPSRRP
CCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCC
TDGRYGENPNRLGSYYQFQVVIKPSPSNIQELYLKSLEVLGINLNEHDIRFVEDNWESPT
CCCCCCCCHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHEEECCCCCCEEEEECCCCCCC
LGAWGLGWEVWLDGMEVTQFTYFQQVGGIACSPIPVEITYGLERLAMYVQKVENILEIEW
CCCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHEEHC
AKKNHDSVNYAQVHLESEYEFSKYHFETASVKRLLEMFKNAQAEALHCLENKLPLPAYDF
CCCCCCCCCEEEEEECCCCCHHHHEECHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHH
VMLCSHFFNILDARKAISVAERQNYILQIRDLAKGCALLYKEQEEEREERLKNALTKAEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GVS
CCC
>Mature Secondary Structure
MQDFSSLLLKLQEYWKNQGCLVIQPYDIPAGAGTFHPATLLRSLDKKPWNVAYVAPSRRP
CCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCC
TDGRYGENPNRLGSYYQFQVVIKPSPSNIQELYLKSLEVLGINLNEHDIRFVEDNWESPT
CCCCCCCCHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHEEECCCCCCEEEEECCCCCCC
LGAWGLGWEVWLDGMEVTQFTYFQQVGGIACSPIPVEITYGLERLAMYVQKVENILEIEW
CCCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHEEHC
AKKNHDSVNYAQVHLESEYEFSKYHFETASVKRLLEMFKNAQAEALHCLENKLPLPAYDF
CCCCCCCCCEEEEEECCCCCHHHHEECHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHH
VMLCSHFFNILDARKAISVAERQNYILQIRDLAKGCALLYKEQEEEREERLKNALTKAEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GVS
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9252185