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The map label for this gene is ruvA

Identifier: 15645501

GI number: 15645501

Start: 932818

End: 933369

Strand: Reverse

Name: ruvA

Synonym: HP0883

Alternate gene names: 15645501

Gene position: 933369-932818 (Counterclockwise)

Preceding gene: 15645502

Following gene: 15645500

Centisome position: 55.96

GC content: 42.21

Gene sequence:

>552_bases
ATGATAGTGGGTTTGATAGGGGTTGTGGAAAAAATCTCCGCTTTAGAAGTGCATATAGAAGTGCAAGGGGTTGTTTATGG
GGTGCAAGTTTCTATGCGAACGGCTGCTTTGCTTGAAGCGGGCCAAAAAGCGCGTTTGAAAATCTTGCAAGTGATCAAAG
AAGATGCACATCTTTTATACGGGTTTTTAGAAGAGGGCGAAAAAATCCTTTTTGAAAGGCTTTTAAAAATCAATGGGGTA
GGGGGGCGTATCGCTTTAGCCATTCTTTCAAGCTTTTCGCCGAACGAATTTGAAAGCATTATCGCCACCAAAGAAGTCAA
AAGACTCCAGCAAGTCCCAGGTATAGGGAAAAAGCTCGCTGATAAGATCATGGTGGATTTGATTGGCTTTTTCATTCAAG
ATGAAAACAGACCCGCACGCAATGAGGTTTTTTTAGCCCTAGAGAGTTTGGGCTTTAAAAGCGCTGAAATCAACCAAGTC
TTAAAAACCCTAAAACCCAATCTCAGCATAGAAGCAGCGATTAAAGAAGCCCTACAACAACTGCGCTCTTAA

Upstream 100 bases:

>100_bases
CATAATGAAAGCGTGAATGTGATCTATGAAGATCATAAAATCAAAAAAGTCCCTAAAAGCGCGATAAAAGGCTAGAACAA
GAAATAAAAAAGGGATAAAA

Downstream 100 bases:

>100_bases
AAAAAGCTTTTTAGTATCCGCTCGCTAAAAACCTAGTAAGAATTTAGAATTAAGCGCGCAAAAATCACACTTTAGCAACA
ACACGCTTAAAATCATTGAA

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MIVGLIGVVEKISALEVHIEVQGVVYGVQVSMRTAALLEAGQKARLKILQVIKEDAHLLYGFLEEGEKILFERLLKINGV
GGRIALAILSSFSPNEFESIIATKEVKRLQQVPGIGKKLADKIMVDLIGFFIQDENRPARNEVFLALESLGFKSAEINQV
LKTLKPNLSIEAAIKEALQQLRS

Sequences:

>Translated_183_residues
MIVGLIGVVEKISALEVHIEVQGVVYGVQVSMRTAALLEAGQKARLKILQVIKEDAHLLYGFLEEGEKILFERLLKINGV
GGRIALAILSSFSPNEFESIIATKEVKRLQQVPGIGKKLADKIMVDLIGFFIQDENRPARNEVFLALESLGFKSAEINQV
LKTLKPNLSIEAAIKEALQQLRS
>Mature_183_residues
MIVGLIGVVEKISALEVHIEVQGVVYGVQVSMRTAALLEAGQKARLKILQVIKEDAHLLYGFLEEGEKILFERLLKINGV
GGRIALAILSSFSPNEFESIIATKEVKRLQQVPGIGKKLADKIMVDLIGFFIQDENRPARNEVFLALESLGFKSAEINQV
LKTLKPNLSIEAAIKEALQQLRS

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=193, Percent_Identity=38.3419689119171, Blast_Score=101, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 20176; Mature: 20176

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVGLIGVVEKISALEVHIEVQGVVYGVQVSMRTAALLEAGQKARLKILQVIKEDAHLLY
CEEHHHHHHHHHHHHEEEEEEEEEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
GFLEEGEKILFERLLKINGVGGRIALAILSSFSPNEFESIIATKEVKRLQQVPGIGKKLA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
DKIMVDLIGFFIQDENRPARNEVFLALESLGFKSAEINQVLKTLKPNLSIEAAIKEALQQ
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHH
LRS
HCC
>Mature Secondary Structure
MIVGLIGVVEKISALEVHIEVQGVVYGVQVSMRTAALLEAGQKARLKILQVIKEDAHLLY
CEEHHHHHHHHHHHHEEEEEEEEEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
GFLEEGEKILFERLLKINGVGGRIALAILSSFSPNEFESIIATKEVKRLQQVPGIGKKLA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
DKIMVDLIGFFIQDENRPARNEVFLALESLGFKSAEINQVLKTLKPNLSIEAAIKEALQQ
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHH
LRS
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA