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Identifier: 15645419

GI number: 15645419

Start: 855886

End: 856323

Strand: Reverse

Name: Not Available

Synonym: HP0800

Alternate gene names: 15645419

Gene position: 856323-855886 (Counterclockwise)

Preceding gene: 15645420

Following gene: 15645418

Centisome position: 51.34

GC content: 37.21

Gene sequence:

>438_bases
GTGTTAAAAATCATTCAAGGGGCATTAGATACTAGGGAGCTTTTAAAAGCCTACCAAGAGGAAGCTTGCGCGAAAAACTT
TGGAGCGTTTTGTGTGTTTGTGGGGATTGTGAGAAAAGAGGATAACATTCAAGGCTTGAGTTTTGATATTTATGAAGCGC
TATTAAAGACTTGGTTTGAAAAATGGCACCATAAAGCCAAAGATTTGGGCGTGGTGTTAAAAATGGCGCACAGCCTGGGC
GATGTTTTGATAGGACAAAGCTCATTTTTATGCGTTTCAATGGGAAAGAATAGAAAAAATGCCTTAGAACTATACGAAAA
TTTTATTGAAGATTTTAAGCATAACGCTCCTATTTGGAAATACGATTTAATCCATAATAAACGCATTTATGCTAAAGAAA
GAAGCCACCCTTTAAAAGGGAGCGGGCTTTTAGCTTAA

Upstream 100 bases:

>100_bases
TTGCGCGATAGCCCTTAATGATCATTTAATAGACAATTTAAACACGCCTTTAAAAGATGGCGATGTAATAAGTTTGTTGC
CACCGGTTTGTGGGGGCTAG

Downstream 100 bases:

>100_bases
AAAGGAGTTCAAATGCAAACGATTCATATAGGCGTTTTGAGCGCGAGCGATAGAGCGTCAAAAGGGATTTATGAAGATTT
AAGCGGTAAGGCGATACAAG

Product: molybdopterin converting factor, subunit 2 (moaE)

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MLKIIQGALDTRELLKAYQEEACAKNFGAFCVFVGIVRKEDNIQGLSFDIYEALLKTWFEKWHHKAKDLGVVLKMAHSLG
DVLIGQSSFLCVSMGKNRKNALELYENFIEDFKHNAPIWKYDLIHNKRIYAKERSHPLKGSGLLA

Sequences:

>Translated_145_residues
MLKIIQGALDTRELLKAYQEEACAKNFGAFCVFVGIVRKEDNIQGLSFDIYEALLKTWFEKWHHKAKDLGVVLKMAHSLG
DVLIGQSSFLCVSMGKNRKNALELYENFIEDFKHNAPIWKYDLIHNKRIYAKERSHPLKGSGLLA
>Mature_145_residues
MLKIIQGALDTRELLKAYQEEACAKNFGAFCVFVGIVRKEDNIQGLSFDIYEALLKTWFEKWHHKAKDLGVVLKMAHSLG
DVLIGQSSFLCVSMGKNRKNALELYENFIEDFKHNAPIWKYDLIHNKRIYAKERSHPLKGSGLLA

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAE_HELPY (P56422)

Other databases:

- EMBL:   AE000511
- PIR:   H64619
- RefSeq:   NP_207593.1
- ProteinModelPortal:   P56422
- SMR:   P56422
- DIP:   DIP-3522N
- MINT:   MINT-169161
- GeneID:   898921
- GenomeReviews:   AE000511_GR
- KEGG:   hpy:HP0800
- NMPDR:   fig|85962.1.peg.791
- TIGR:   HP_0800
- HOGENOM:   HBG321032
- OMA:   APIWKYD
- ProtClustDB:   CLSK872449
- InterPro:   IPR003448
- Gene3D:   G3DSA:3.90.1170.40

Pfam domain/function: PF02391 MoaE; SSF54690 Mb_biosynth_MoaE

EC number: NA

Molecular weight: Translated: 16628; Mature: 16628

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: BINDING 113-113

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIIQGALDTRELLKAYQEEACAKNFGAFCVFVGIVRKEDNIQGLSFDIYEALLKTWFE
CCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
KWHHKAKDLGVVLKMAHSLGDVLIGQSSFLCVSMGKNRKNALELYENFIEDFKHNAPIWK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEE
YDLIHNKRIYAKERSHPLKGSGLLA
EECHHCCCHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MLKIIQGALDTRELLKAYQEEACAKNFGAFCVFVGIVRKEDNIQGLSFDIYEALLKTWFE
CCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
KWHHKAKDLGVVLKMAHSLGDVLIGQSSFLCVSMGKNRKNALELYENFIEDFKHNAPIWK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEE
YDLIHNKRIYAKERSHPLKGSGLLA
EECHHCCCHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9252185