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The map label for this gene is moaC

Identifier: 15645417

GI number: 15645417

Start: 854858

End: 855334

Strand: Reverse

Name: moaC

Synonym: HP0798

Alternate gene names: 15645417

Gene position: 855334-854858 (Counterclockwise)

Preceding gene: 15645418

Following gene: 15645416

Centisome position: 51.28

GC content: 40.67

Gene sequence:

>477_bases
ATGCCGCTCACTCATTTGAATGAAGAAAATCAGCCTAAAATGGTGGATATAGGGGATAAAGAAACCACTGAAAGAATCGC
TTTAGCAAGCGGTCGTATCAGCATGAATAAAGAGGCTTATGACGCTATTATCAATCATTGCGTCAAAAAGGGTCCGGTGT
TACAGACTGCTATTATTGCTGGAATTATGGGGGCTAAAAAGACAAGCGAGCTCATTCCCATGTGCCATCCAATCATGCTC
AATGGGGTGGATATTGATATTTTAGAAGAAAAAGAGACTTGTAGTTTTAAACTCTATGCGAGAGTCAAAACTCAAGCTAA
AACGGGCGTAGAAATGGAAGCGCTAATGAGTGTGAGCATAGGGCTTTTAACCATTTATGACATGGTGAAAGCCATTGACA
AGAGCATGACAATTAGCGGTGTGATGTTGGAGCATAAAAGTGGAGGCAAAAGTGGGGATTATAACGCTAAAAAATAG

Upstream 100 bases:

>100_bases
TTCCAGCGATTCCTTATTGCGTGGATTTGATTTTAGGGAATTATATGCAAGTGAATGAAAAAAACATTCAAGCGTTTCGC
CCCAAACAATAGGATAAAAA

Downstream 100 bases:

>100_bases
AAAAAGACCAATAATCTAAAGATGTTAGGGTAAAATAACATTTTGACAACAAAAGCGTGTTGGTTGCTTCGGGTTTGTTG
TTATAGAAGTCTAAAATATT

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MPLTHLNEENQPKMVDIGDKETTERIALASGRISMNKEAYDAIINHCVKKGPVLQTAIIAGIMGAKKTSELIPMCHPIML
NGVDIDILEEKETCSFKLYARVKTQAKTGVEMEALMSVSIGLLTIYDMVKAIDKSMTISGVMLEHKSGGKSGDYNAKK

Sequences:

>Translated_158_residues
MPLTHLNEENQPKMVDIGDKETTERIALASGRISMNKEAYDAIINHCVKKGPVLQTAIIAGIMGAKKTSELIPMCHPIML
NGVDIDILEEKETCSFKLYARVKTQAKTGVEMEALMSVSIGLLTIYDMVKAIDKSMTISGVMLEHKSGGKSGDYNAKK
>Mature_157_residues
PLTHLNEENQPKMVDIGDKETTERIALASGRISMNKEAYDAIINHCVKKGPVLQTAIIAGIMGAKKTSELIPMCHPIMLN
GVDIDILEEKETCSFKLYARVKTQAKTGVEMEALMSVSIGLLTIYDMVKAIDKSMTISGVMLEHKSGGKSGDYNAKK

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=152, Percent_Identity=46.0526315789474, Blast_Score=132, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=42.9530201342282, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28574490, Length=148, Percent_Identity=45.2702702702703, Blast_Score=127, Evalue=4e-30,
Organism=Drosophila melanogaster, GI28574492, Length=137, Percent_Identity=46.7153284671533, Blast_Score=118, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17272; Mature: 17140

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
7.0 %Met     (Translated Protein)
8.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
6.4 %Met     (Mature Protein)
8.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLTHLNEENQPKMVDIGDKETTERIALASGRISMNKEAYDAIINHCVKKGPVLQTAIIA
CCCCCCCCCCCCCEEECCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
GIMGAKKTSELIPMCHPIMLNGVDIDILEEKETCSFKLYARVKTQAKTGVEMEALMSVSI
HHHCCCCCHHHCCCCCCEEECCCCEEEECCCCCCCEEEEEEEEHHHHCCCHHHHHHHHHH
GLLTIYDMVKAIDKSMTISGVMLEHKSGGKSGDYNAKK
HHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
PLTHLNEENQPKMVDIGDKETTERIALASGRISMNKEAYDAIINHCVKKGPVLQTAIIA
CCCCCCCCCCCCEEECCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
GIMGAKKTSELIPMCHPIMLNGVDIDILEEKETCSFKLYARVKTQAKTGVEMEALMSVSI
HHHCCCCCHHHCCCCCCEEECCCCEEEECCCCCCCEEEEEEEEHHHHCCCHHHHHHHHHH
GLLTIYDMVKAIDKSMTISGVMLEHKSGGKSGDYNAKK
HHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA