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Identifier: 15645276

GI number: 15645276

Start: 698132

End: 698755

Strand: Reverse

Name: Not Available

Synonym: HP0652

Alternate gene names: 15645276

Gene position: 698755-698132 (Counterclockwise)

Preceding gene: 15645277

Following gene: 15645275

Centisome position: 41.9

GC content: 41.67

Gene sequence:

>624_bases
GTGCAAAAACTAGCCGTTTTTGATTTTGACTCCACGCTAGTCAATGCTGAGACGATTGAGTCTTTAGCGAGGGCGTGGGG
GGTTTTTGATGAAGTGAAAACAATCACTTTGAAAGCTATGAATGGCGAGACAGATTTTCATAAAAGTCTTATTTTAAGGG
TTTCCAAACTCAAAAACATGCCCTTAAAACTAGCCAAAGAAGTTTGTGAAAGTCTGCCTTTATTTGAAGGAGCGCTTGAG
CTTGTTAGTGCCTTAAAAGAGAAAAATTACAAGGTGGTTTGCTTCAGCGGAGGCTTTGATCTAGCGACCAATCATTACAG
GGATTTATTGCATTTAGATGCGGCTTTCAGCAACACGCTGATAGTGGAAAATGACGCCTTAAACGGCTTGGTTACGGGGC
ATATGATGTTTTCACACTCTAAGGGCGAAATGCTACTCGTTTTACAACGCTTGTTGAATATCAGCAAAACGAACACTTTA
GTCGTGGGCGATGGGGCGAATGACTTGAGCATGTTCAAGCATGCCCACATTAAAATCGCTTTCAACGCTAAAGAGGTTTT
AAAACAGCACGCTACGCATTGCATCAATGAGCCTGATTTAGCCCTAATCAAGCCTTTGATTTAA

Upstream 100 bases:

>100_bases
AAATTGAGTTGATTGGTAATGAAAACCATGGCTTGTATTTGGCTGATCAGTATGTCAAAGGGATCGCTAAAAGCAGGAAA
TCTTAATTTTAGGGTATTGG

Downstream 100 bases:

>100_bases
AAAAATTTTTTTGTAAAATACTCCTTTTAAAGGATAACCATGTTCCAACCCCTATTAGACGCCTTTATAGAAAGCGCTTC
CATTGAAAAAATGGTCTCTA

Product: phosphoserine phosphatase (serB)

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MQKLAVFDFDSTLVNAETIESLARAWGVFDEVKTITLKAMNGETDFHKSLILRVSKLKNMPLKLAKEVCESLPLFEGALE
LVSALKEKNYKVVCFSGGFDLATNHYRDLLHLDAAFSNTLIVENDALNGLVTGHMMFSHSKGEMLLVLQRLLNISKTNTL
VVGDGANDLSMFKHAHIKIAFNAKEVLKQHATHCINEPDLALIKPLI

Sequences:

>Translated_207_residues
MQKLAVFDFDSTLVNAETIESLARAWGVFDEVKTITLKAMNGETDFHKSLILRVSKLKNMPLKLAKEVCESLPLFEGALE
LVSALKEKNYKVVCFSGGFDLATNHYRDLLHLDAAFSNTLIVENDALNGLVTGHMMFSHSKGEMLLVLQRLLNISKTNTL
VVGDGANDLSMFKHAHIKIAFNAKEVLKQHATHCINEPDLALIKPLI
>Mature_207_residues
MQKLAVFDFDSTLVNAETIESLARAWGVFDEVKTITLKAMNGETDFHKSLILRVSKLKNMPLKLAKEVCESLPLFEGALE
LVSALKEKNYKVVCFSGGFDLATNHYRDLLHLDAAFSNTLIVENDALNGLVTGHMMFSHSKGEMLLVLQRLLNISKTNTL
VVGDGANDLSMFKHAHIKIAFNAKEVLKQHATHCINEPDLALIKPLI

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=191, Percent_Identity=30.8900523560209, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1790849, Length=197, Percent_Identity=36.5482233502538, Blast_Score=119, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6321647, Length=195, Percent_Identity=38.974358974359, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 22991; Mature: 22991

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKLAVFDFDSTLVNAETIESLARAWGVFDEVKTITLKAMNGETDFHKSLILRVSKLKNM
CCCEEEEECCCHHCCHHHHHHHHHHHCCHHHHHEEEEEEECCCCHHHHHHHHHHHHHCCC
PLKLAKEVCESLPLFEGALELVSALKEKNYKVVCFSGGFDLATNHYRDLLHLDAAFSNTL
CHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCEE
IVENDALNGLVTGHMMFSHSKGEMLLVLQRLLNISKTNTLVVGDGANDLSMFKHAHIKIA
EEECCCCCCEEEEEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHEEEEEE
FNAKEVLKQHATHCINEPDLALIKPLI
ECHHHHHHHHHHHCCCCCCHHHHCCCC
>Mature Secondary Structure
MQKLAVFDFDSTLVNAETIESLARAWGVFDEVKTITLKAMNGETDFHKSLILRVSKLKNM
CCCEEEEECCCHHCCHHHHHHHHHHHCCHHHHHEEEEEEECCCCHHHHHHHHHHHHHCCC
PLKLAKEVCESLPLFEGALELVSALKEKNYKVVCFSGGFDLATNHYRDLLHLDAAFSNTL
CHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCEE
IVENDALNGLVTGHMMFSHSKGEMLLVLQRLLNISKTNTLVVGDGANDLSMFKHAHIKIA
EEECCCCCCEEEEEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHEEEEEE
FNAKEVLKQHATHCINEPDLALIKPLI
ECHHHHHHHHHHHCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087; 11342136; 12051918 [H]