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Identifier: 15645199

GI number: 15645199

Start: 605293

End: 605748

Strand: Reverse

Name: Not Available

Synonym: HP0574

Alternate gene names: 15645199

Gene position: 605748-605293 (Counterclockwise)

Preceding gene: 15645200

Following gene: 15645198

Centisome position: 36.32

GC content: 42.11

Gene sequence:

>456_bases
ATGAATAAGCTCTTAAAGTTTTCTCAAGTTTTTATAGGCAGCGATCATGCAGGGTTGCATCTTGCAGAGTTTGTCCAGCG
TTTTTTAGAAGACAAGGATTTTAAGATCCAAGCTTTTTTACCCACCATGAGAGTGGATTACCCTGATTACGCCAAATTAG
TGTGCCAAAAGGTCTTAGAAAATGCGCAAAGCTATGGCATTTTAGTGTGCGCCACAGGGATAGGCATGAGCATGGGCGCT
AATCGCTTTAAGGGTATTAGAGCCGCTTTGTGCCTTGATGCTTACATGGCTAAAATGACTCGCTTGCACAATAACGCTAA
TGTTTTGTGTTTGGGCGAAAAGATTAGCGGCATTGGCGTGGTGGAAAGCATTTTAGAAGCGTTTTTCTCTACAGAATTTG
AACAAGGCCGTCATGTGTTGCGCATCCAAAAACTAGATGAATCGCTGAAATCATAA

Upstream 100 bases:

>100_bases
TTTTTTTGTTTATCCCCCCTTTATCGGAGTTTTTTATCCATGCGCCCACAAGATTTTTATTTTCTTTACTCCTCTCTTAA
TCTTTTATCAAGGAGAGTTT

Downstream 100 bases:

>100_bases
ACCTAATGTAGTATAATTACATCGTTTCGCTAAAAAGGATATTTTAACAGAATGTTTACCCAATGGTTTATTCTCACTAT
CGCTATTGTTTTTATCCTTT

Product: ribose-5-phosphate isomerase B

Products: D-ribulose 5-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MNKLLKFSQVFIGSDHAGLHLAEFVQRFLEDKDFKIQAFLPTMRVDYPDYAKLVCQKVLENAQSYGILVCATGIGMSMGA
NRFKGIRAALCLDAYMAKMTRLHNNANVLCLGEKISGIGVVESILEAFFSTEFEQGRHVLRIQKLDESLKS

Sequences:

>Translated_151_residues
MNKLLKFSQVFIGSDHAGLHLAEFVQRFLEDKDFKIQAFLPTMRVDYPDYAKLVCQKVLENAQSYGILVCATGIGMSMGA
NRFKGIRAALCLDAYMAKMTRLHNNANVLCLGEKISGIGVVESILEAFFSTEFEQGRHVLRIQKLDESLKS
>Mature_151_residues
MNKLLKFSQVFIGSDHAGLHLAEFVQRFLEDKDFKIQAFLPTMRVDYPDYAKLVCQKVLENAQSYGILVCATGIGMSMGA
NRFKGIRAALCLDAYMAKMTRLHNNANVLCLGEKISGIGVVESILEAFFSTEFEQGRHVLRIQKLDESLKS

Specific function: In Addition To Its Activity On D-Ribose 5-Phosphate It Probably Also Has Activity On D-Allose 6-Phosphate. [C]

COG id: COG0698

COG function: function code G; Ribose 5-phosphate isomerase RpiB

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacAB/rpiB family [H]

Homologues:

Organism=Escherichia coli, GI1790528, Length=142, Percent_Identity=35.9154929577465, Blast_Score=103, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003500
- InterPro:   IPR004785 [H]

Pfam domain/function: PF02502 LacAB_rpiB [H]

EC number: 5.3.1.6

Molecular weight: Translated: 16924; Mature: 16924

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLLKFSQVFIGSDHAGLHLAEFVQRFLEDKDFKIQAFLPTMRVDYPDYAKLVCQKVLE
CCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEECCHHCCCCCHHHHHHHHHHHH
NAQSYGILVCATGIGMSMGANRFKGIRAALCLDAYMAKMTRLHNNANVLCLGEKISGIGV
HHHHCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHH
VESILEAFFSTEFEQGRHVLRIQKLDESLKS
HHHHHHHHHHCHHHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNKLLKFSQVFIGSDHAGLHLAEFVQRFLEDKDFKIQAFLPTMRVDYPDYAKLVCQKVLE
CCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEECCHHCCCCCHHHHHHHHHHHH
NAQSYGILVCATGIGMSMGANRFKGIRAALCLDAYMAKMTRLHNNANVLCLGEKISGIGV
HHHHCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHH
VESILEAFFSTEFEQGRHVLRIQKLDESLKS
HHHHHHHHHHCHHHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 4.4 {D-ribose} 0.83 {D-ribose} [C]

Substrates: D-ribose 5-phosphate

Specific reaction: D-ribose 5-phosphate = D-ribulose 5-phosphate

General reaction: Intramolecular oxidoreduction; Isomerization [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]