Click here to switch to the map view.

The map label for this gene is Not Available

Identifier: 15645183

GI number: 15645183

Start: 592491

End: 593729

Strand: Reverse

Name: Not Available

Synonym: HP0558

Alternate gene names: 15645183

Gene position: 593729-592491 (Counterclockwise)

Preceding gene: 15645184

Following gene: 15645182

Centisome position: 35.6

GC content: 44.87

Gene sequence:

>1239_bases
GTGCGTCGGATTGTAGTAACTGGAATGGGAATGATCAATTCGCTAGGTTTAAATAAAGAAGATTCTTTTTTAGCGATCGC
TAAAGGGGAATGCGGTATCAAACACATAGAAAGTTTTGATGCGAGCGCGTTTCCTGTGCGTATTGCTGGAGAAATCACTG
ACTTTGACCCTACAGAGGTGATGAATCCCAAAGATGTTAAAAAGGCGGGTCGTTTCATTCAATTAGCCTTGAAAGCCACA
AGAGAGGCGATGAAAGATAGTGGGATTTTAGACGCTCACAATAGATGCCCTGAAGAATTGGCAAATCGCATGGGCGTAAG
CTCTGGCTCTGGGATTGGCGGGTTAGGCAATATTGAAGCGAATTCCATTTTTTGTTTTGAAAAAGGCCCTAGAAAAGTCA
ATCCCTTTTTCATCACTTCTGCGTTAGTGAATATGATTGGTGGTTTCACTTCCATTGAGTTTGGCATTAAAGGGCCTAAT
CTCTCTAGCGTAACGGCTTGTGCAGCAGGCACTCATGCCATTATTGAAGCCGTTAAAACCATTTTGCTTAATGGGGCTGA
TAAAATGCTAGTCGTGGGAGCGGAATCCACCATTTGTCCTGTAGGGATTGGGGGGTTTGCGAGCATTAAAGCCCTTTCTA
CAAGGAATGATGATCCTAAAAAAGCTTCAAGACCTTTTGATAAGGATCGCAATGGCTTTGTGATGGGCGAAGGCGCTGGG
GCTTTGGTGCTTGAAGAATACGAGAGCGCGAAAAGAAGAGGGGCAAAAATTTATGCAGAATTTGCCGGGTATGGCGAGAG
TGGCGATGCTAACCATATCACAGCCCCAGCCCCTGAGGGCGAAGGGGCTTTTAGAGCCATGAAGATGGCTTTAGAAATGG
CGAAAGTGGAAATAGGCTATGTGAACGCTCATGGGACTAGCACGCATTATAACGATCTATATGAAAGCATCGCTCTAAAA
AATGTGTTTGGTTCTAAAGAAAAAGTCCCTCCTGTCAGCTCCACTAAAGGGCAGATTGGGCATTGCTTGGGTGCTGCGGG
CGCGTTAGAAGCCGTTATTTCTATCATGGCCATGAATCAAGGAATCTTACCTCCTACCATCAATCAAGAAATGCCTGACC
CAGAATGCGATTTGGATTATATCCCTAATGCGGCCAGAGAAAAGCGAGTGGATGCAGTGATGAGTAACTCATTTGGTTTT
GGTGGCACTAATGGTGTTGTGATTTTCAAAAAAGCCTAG

Upstream 100 bases:

>100_bases
TTTCGTGTTAGCATTCAATGGAATGCTTTAGTTAGGAAGCTCCTTGCTTTAAGCAAGGGGTGGTTTCACTGAATTAAAGT
TTTGAAATGAGGAGCTATTG

Downstream 100 bases:

>100_bases
TTTTACAAAGTTAGGATTTTGAATGGCCGTTTATTTAGATTTTGAAAATCATATTAAAGAGATTCAAAATGAAATTGAAT
TAGCCCTTATTAGAGGCGAT

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MRRIVVTGMGMINSLGLNKEDSFLAIAKGECGIKHIESFDASAFPVRIAGEITDFDPTEVMNPKDVKKAGRFIQLALKAT
REAMKDSGILDAHNRCPEELANRMGVSSGSGIGGLGNIEANSIFCFEKGPRKVNPFFITSALVNMIGGFTSIEFGIKGPN
LSSVTACAAGTHAIIEAVKTILLNGADKMLVVGAESTICPVGIGGFASIKALSTRNDDPKKASRPFDKDRNGFVMGEGAG
ALVLEEYESAKRRGAKIYAEFAGYGESGDANHITAPAPEGEGAFRAMKMALEMAKVEIGYVNAHGTSTHYNDLYESIALK
NVFGSKEKVPPVSSTKGQIGHCLGAAGALEAVISIMAMNQGILPPTINQEMPDPECDLDYIPNAAREKRVDAVMSNSFGF
GGTNGVVIFKKA

Sequences:

>Translated_412_residues
MRRIVVTGMGMINSLGLNKEDSFLAIAKGECGIKHIESFDASAFPVRIAGEITDFDPTEVMNPKDVKKAGRFIQLALKAT
REAMKDSGILDAHNRCPEELANRMGVSSGSGIGGLGNIEANSIFCFEKGPRKVNPFFITSALVNMIGGFTSIEFGIKGPN
LSSVTACAAGTHAIIEAVKTILLNGADKMLVVGAESTICPVGIGGFASIKALSTRNDDPKKASRPFDKDRNGFVMGEGAG
ALVLEEYESAKRRGAKIYAEFAGYGESGDANHITAPAPEGEGAFRAMKMALEMAKVEIGYVNAHGTSTHYNDLYESIALK
NVFGSKEKVPPVSSTKGQIGHCLGAAGALEAVISIMAMNQGILPPTINQEMPDPECDLDYIPNAAREKRVDAVMSNSFGF
GGTNGVVIFKKA
>Mature_412_residues
MRRIVVTGMGMINSLGLNKEDSFLAIAKGECGIKHIESFDASAFPVRIAGEITDFDPTEVMNPKDVKKAGRFIQLALKAT
REAMKDSGILDAHNRCPEELANRMGVSSGSGIGGLGNIEANSIFCFEKGPRKVNPFFITSALVNMIGGFTSIEFGIKGPN
LSSVTACAAGTHAIIEAVKTILLNGADKMLVVGAESTICPVGIGGFASIKALSTRNDDPKKASRPFDKDRNGFVMGEGAG
ALVLEEYESAKRRGAKIYAEFAGYGESGDANHITAPAPEGEGAFRAMKMALEMAKVEIGYVNAHGTSTHYNDLYESIALK
NVFGSKEKVPPVSSTKGQIGHCLGAAGALEAVISIMAMNQGILPPTINQEMPDPECDLDYIPNAAREKRVDAVMSNSFGF
GGTNGVVIFKKA

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=420, Percent_Identity=42.3809523809524, Blast_Score=302, Evalue=4e-82,
Organism=Homo sapiens, GI223972627, Length=146, Percent_Identity=50, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI41872631, Length=388, Percent_Identity=24.4845360824742, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI1787337, Length=414, Percent_Identity=49.2753623188406, Blast_Score=359, Evalue=1e-100,
Organism=Escherichia coli, GI1788663, Length=419, Percent_Identity=36.2768496420048, Blast_Score=237, Evalue=9e-64,
Organism=Caenorhabditis elegans, GI71983541, Length=421, Percent_Identity=36.104513064133, Blast_Score=222, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI71983535, Length=264, Percent_Identity=42.0454545454545, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI212642053, Length=429, Percent_Identity=26.1072261072261, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17550940, Length=273, Percent_Identity=27.8388278388278, Blast_Score=85, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6320904, Length=446, Percent_Identity=35.2017937219731, Blast_Score=238, Evalue=2e-63,
Organism=Drosophila melanogaster, GI24644341, Length=418, Percent_Identity=41.6267942583732, Blast_Score=277, Evalue=1e-74,
Organism=Drosophila melanogaster, GI221330659, Length=392, Percent_Identity=27.8061224489796, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI19920632, Length=392, Percent_Identity=27.8061224489796, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24581345, Length=398, Percent_Identity=26.8844221105528, Blast_Score=92, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 43564; Mature: 43564

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRIVVTGMGMINSLGLNKEDSFLAIAKGECGIKHIESFDASAFPVRIAGEITDFDPTEV
CCEEEEECCCHHHHCCCCCCCCEEEEECCCCCHHHHHHCCCCCCCEEEECCCCCCCCHHC
MNPKDVKKAGRFIQLALKATREAMKDSGILDAHNRCPEELANRMGVSSGSGIGGLGNIEA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHCCCCCCCCCCCCCCCCC
NSIFCFEKGPRKVNPFFITSALVNMIGGFTSIEFGIKGPNLSSVTACAAGTHAIIEAVKT
CEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHCCHHHHHHHHHH
ILLNGADKMLVVGAESTICPVGIGGFASIKALSTRNDDPKKASRPFDKDRNGFVMGEGAG
HHHCCCCCEEEEECCCCCCEECCCCHHHEEEECCCCCCCHHHCCCCCCCCCCEEEECCCC
ALVLEEYESAKRRGAKIYAEFAGYGESGDANHITAPAPEGEGAFRAMKMALEMAKVEIGY
EEEHHHHHHHHHCCCEEEEEECCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHEEEEE
VNAHGTSTHYNDLYESIALKNVFGSKEKVPPVSSTKGQIGHCLGAAGALEAVISIMAMNQ
EECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
GILPPTINQEMPDPECDLDYIPNAAREKRVDAVMSNSFGFGGTNGVVIFKKA
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECC
>Mature Secondary Structure
MRRIVVTGMGMINSLGLNKEDSFLAIAKGECGIKHIESFDASAFPVRIAGEITDFDPTEV
CCEEEEECCCHHHHCCCCCCCCEEEEECCCCCHHHHHHCCCCCCCEEEECCCCCCCCHHC
MNPKDVKKAGRFIQLALKATREAMKDSGILDAHNRCPEELANRMGVSSGSGIGGLGNIEA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHCCCCCCCCCCCCCCCCC
NSIFCFEKGPRKVNPFFITSALVNMIGGFTSIEFGIKGPNLSSVTACAAGTHAIIEAVKT
CEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHCCHHHHHHHHHH
ILLNGADKMLVVGAESTICPVGIGGFASIKALSTRNDDPKKASRPFDKDRNGFVMGEGAG
HHHCCCCCEEEEECCCCCCEECCCCHHHEEEECCCCCCCHHHCCCCCCCCCCEEEECCCC
ALVLEEYESAKRRGAKIYAEFAGYGESGDANHITAPAPEGEGAFRAMKMALEMAKVEIGY
EEEHHHHHHHHHCCCEEEEEECCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHEEEEE
VNAHGTSTHYNDLYESIALKNVFGSKEKVPPVSSTKGQIGHCLGAAGALEAVISIMAMNQ
EECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
GILPPTINQEMPDPECDLDYIPNAAREKRVDAVMSNSFGFGGTNGVVIFKKA
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12704232 [H]