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The map label for this gene is argS

Identifier: 15644947

GI number: 15644947

Start: 335204

End: 336829

Strand: Reverse

Name: argS

Synonym: HP0319

Alternate gene names: 15644947

Gene position: 336829-335204 (Counterclockwise)

Preceding gene: 15644948

Following gene: 15644946

Centisome position: 20.2

GC content: 38.44

Gene sequence:

>1626_bases
ATGCACACTCTCATTAAGGGCATTTTAGAAGAGATTTTAGAAGAAGAAGTCATTGTTGAATACCCTAAAGACAGAGAGCA
TGGGCATTACGCTACGCCCATTGCTTTCAATCTCGCCAAAGTTTTTAAAAAATCGCCCTTAGCCATCGCTGAAGAGTTAG
CCCTTAAAATCAGCACGCATGAAAAAACTCAAGGGCTTTTTGACAGCGTAGTGGCTTGTAAGGGCTATATCAATTTCACG
CTTTCTTTAGATTTTTTGGAGCGTTTCACCCAAAAAGCTTTGGAATTGAAAGAAAAATTTGGCTCTCAAGTTAAAAGCGA
ACGTTCTCAAAAAATCTTTTTAGAATTTGTGAGCGCTAACCCCACAGGGCCTTTACACATAGGGCATGCTAGAGGGGCGG
TGTTTGGCGATAGTTTGGCTAAAATCGCTCGCTTTTTAGGGCATGAAGTTTTATGCGAGTATTATGTCAATGACATGGGA
TCTCAAATCCGCTTGTTAGGGCTTTCTGTATGGCTCGCTTACAGAGAACATGTTTTAAAAGAAAGCGTAACTTACCCAGA
AGTCTTTTACAAAGGCGAATACATCATTGAAATCGCTAAAAAGGCGAACAACGATTTAGAACCAAGCCTTTTAAAAGAAA
ACGAAGAAACGATTATTGAAGTTTTAAGCGGCTATGCTAGGGATCTAATGCTTTTAGAAATTAAAGATAATTTAGACGCT
TTAGGCATTCATTTTGATTCCTATGCGAGCGAAAAAGAAGTTTTTAAACATAAAGATGCGGTGTTTGAACAATTAGAAAA
AGCGAACGCCCTTTATGAAAAGGATTCTAAAATCTGGCTCAAATCTTCACTCTACCAGGATGAAAGCGATCGGGTGCTCA
TTAAAGAAGATAAAAGCTACACTTATTTAGCGGGCGATATTGTCTATCATGATGAAAAATTCAAGCAAGATTATACCAAA
TACATCAACATTTGGGGGGCAGACCACCACGGCTATATCGCTAGAGTGAAAGCCAGCCTTGAGTTTTTGGGCTATGATTC
CAACAAGCTTGAAGTCTTGCTCGCTCAAATGGTGCGCTTGCTCAAAGATAACGAGCCTTACAAGATGAGTAAAAGAGCGG
GTAATTTTATTTTGATTAAAGATGTGGTTGATGATGTGGGTAAGGACGCTTTGAGGTTTATTTTTTTGAGCAAACGGCTT
GACACTCATTTAGAATTTGATGTCAATACTTTAAAAAAGCAAGACAGCTCAAACCCCATTTACTATATCCATTACGCTAA
TTCGCGCATCCACACCATGCTAGAAAAATCGCCCTTTTCTAAAGAAGAGGTTTTGCAAACCCCTTTAACCAATTTAAACG
CTGAAGAAAAATACTTGCTTTTTAGCGCTTTAAGCTTGCCTAAAGCAATTGAATCCTCTTTTGAAGAATACGGCTTGCAA
AAAATGTGCGAATACGCAAAAACCCTCGCATCAGAATTCCACCGCTTCTATAACGCTGGCAAAATCTTAGACACCCCTAA
AGCTAAAGAGCTTTTAAAAATTTGTTTAATAGTAAGCTTGAGCTTAAGCAACGCTTTTAAACTTTTAGGCATAGAGATAA
AGACCAAAATTTCCGCTAGAGATTAA

Upstream 100 bases:

>100_bases
AAGAAGAGGCTAAAAACGAGCCAAAAACCCTAGACGCTCAAGCAACGCAAACCAAAGTGCATGAGAGTAGCGAGATTAAA
AGCAAACAAGAAAGTTAAGC

Downstream 100 bases:

>100_bases
GCCAATATTTAATTTTTTGTTATAACATTCCCCTTATTTTTTGAAACTAAGGAGAATATTATGCTTAATCGTATCATAGA
ACACATGAACGCTCACCATG

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MHTLIKGILEEILEEEVIVEYPKDREHGHYATPIAFNLAKVFKKSPLAIAEELALKISTHEKTQGLFDSVVACKGYINFT
LSLDFLERFTQKALELKEKFGSQVKSERSQKIFLEFVSANPTGPLHIGHARGAVFGDSLAKIARFLGHEVLCEYYVNDMG
SQIRLLGLSVWLAYREHVLKESVTYPEVFYKGEYIIEIAKKANNDLEPSLLKENEETIIEVLSGYARDLMLLEIKDNLDA
LGIHFDSYASEKEVFKHKDAVFEQLEKANALYEKDSKIWLKSSLYQDESDRVLIKEDKSYTYLAGDIVYHDEKFKQDYTK
YINIWGADHHGYIARVKASLEFLGYDSNKLEVLLAQMVRLLKDNEPYKMSKRAGNFILIKDVVDDVGKDALRFIFLSKRL
DTHLEFDVNTLKKQDSSNPIYYIHYANSRIHTMLEKSPFSKEEVLQTPLTNLNAEEKYLLFSALSLPKAIESSFEEYGLQ
KMCEYAKTLASEFHRFYNAGKILDTPKAKELLKICLIVSLSLSNAFKLLGIEIKTKISARD

Sequences:

>Translated_541_residues
MHTLIKGILEEILEEEVIVEYPKDREHGHYATPIAFNLAKVFKKSPLAIAEELALKISTHEKTQGLFDSVVACKGYINFT
LSLDFLERFTQKALELKEKFGSQVKSERSQKIFLEFVSANPTGPLHIGHARGAVFGDSLAKIARFLGHEVLCEYYVNDMG
SQIRLLGLSVWLAYREHVLKESVTYPEVFYKGEYIIEIAKKANNDLEPSLLKENEETIIEVLSGYARDLMLLEIKDNLDA
LGIHFDSYASEKEVFKHKDAVFEQLEKANALYEKDSKIWLKSSLYQDESDRVLIKEDKSYTYLAGDIVYHDEKFKQDYTK
YINIWGADHHGYIARVKASLEFLGYDSNKLEVLLAQMVRLLKDNEPYKMSKRAGNFILIKDVVDDVGKDALRFIFLSKRL
DTHLEFDVNTLKKQDSSNPIYYIHYANSRIHTMLEKSPFSKEEVLQTPLTNLNAEEKYLLFSALSLPKAIESSFEEYGLQ
KMCEYAKTLASEFHRFYNAGKILDTPKAKELLKICLIVSLSLSNAFKLLGIEIKTKISARD
>Mature_541_residues
MHTLIKGILEEILEEEVIVEYPKDREHGHYATPIAFNLAKVFKKSPLAIAEELALKISTHEKTQGLFDSVVACKGYINFT
LSLDFLERFTQKALELKEKFGSQVKSERSQKIFLEFVSANPTGPLHIGHARGAVFGDSLAKIARFLGHEVLCEYYVNDMG
SQIRLLGLSVWLAYREHVLKESVTYPEVFYKGEYIIEIAKKANNDLEPSLLKENEETIIEVLSGYARDLMLLEIKDNLDA
LGIHFDSYASEKEVFKHKDAVFEQLEKANALYEKDSKIWLKSSLYQDESDRVLIKEDKSYTYLAGDIVYHDEKFKQDYTK
YINIWGADHHGYIARVKASLEFLGYDSNKLEVLLAQMVRLLKDNEPYKMSKRAGNFILIKDVVDDVGKDALRFIFLSKRL
DTHLEFDVNTLKKQDSSNPIYYIHYANSRIHTMLEKSPFSKEEVLQTPLTNLNAEEKYLLFSALSLPKAIESSFEEYGLQ
KMCEYAKTLASEFHRFYNAGKILDTPKAKELLKICLIVSLSLSNAFKLLGIEIKTKISARD

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI197100773, Length=331, Percent_Identity=25.0755287009063, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1788184, Length=561, Percent_Identity=23.3511586452763, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6321883, Length=555, Percent_Identity=22.5225225225225, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28571570, Length=299, Percent_Identity=28.4280936454849, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 62078; Mature: 62078

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTLIKGILEEILEEEVIVEYPKDREHGHYATPIAFNLAKVFKKSPLAIAEELALKISTH
CHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCC
EKTQGLFDSVVACKGYINFTLSLDFLERFTQKALELKEKFGSQVKSERSQKIFLEFVSAN
HHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCC
PTGPLHIGHARGAVFGDSLAKIARFLGHEVLCEYYVNDMGSQIRLLGLSVWLAYREHVLK
CCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHH
ESVTYPEVFYKGEYIIEIAKKANNDLEPSLLKENEETIIEVLSGYARDLMLLEIKDNLDA
HCCCCCHHHCCCHHEEEEHHHCCCCCCCHHHCCCHHHHHHHHHHHHHCEEEEEECCCCCE
LGIHFDSYASEKEVFKHKDAVFEQLEKANALYEKDSKIWLKSSLYQDESDRVLIKEDKSY
EEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHCCCCCCEEEEEECCCE
TYLAGDIVYHDEKFKQDYTKYINIWGADHHGYIARVKASLEFLGYDSNKLEVLLAQMVRL
EEEEEEEEECCHHHHHHHHHHEEEECCCCCCCCEEEEEHHHEECCCCCHHHHHHHHHHHH
LKDNEPYKMSKRAGNFILIKDVVDDVGKDALRFIFLSKRLDTHLEFDVNTLKKQDSSNPI
HCCCCCCCHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHCCCCCCCE
YYIHYANSRIHTMLEKSPFSKEEVLQTPLTNLNAEEKYLLFSALSLPKAIESSFEEYGLQ
EEEEECCCHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHH
KMCEYAKTLASEFHRFYNAGKILDTPKAKELLKICLIVSLSLSNAFKLLGIEIKTKISAR
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEEEEECCCC
D
C
>Mature Secondary Structure
MHTLIKGILEEILEEEVIVEYPKDREHGHYATPIAFNLAKVFKKSPLAIAEELALKISTH
CHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCC
EKTQGLFDSVVACKGYINFTLSLDFLERFTQKALELKEKFGSQVKSERSQKIFLEFVSAN
HHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCC
PTGPLHIGHARGAVFGDSLAKIARFLGHEVLCEYYVNDMGSQIRLLGLSVWLAYREHVLK
CCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHH
ESVTYPEVFYKGEYIIEIAKKANNDLEPSLLKENEETIIEVLSGYARDLMLLEIKDNLDA
HCCCCCHHHCCCHHEEEEHHHCCCCCCCHHHCCCHHHHHHHHHHHHHCEEEEEECCCCCE
LGIHFDSYASEKEVFKHKDAVFEQLEKANALYEKDSKIWLKSSLYQDESDRVLIKEDKSY
EEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHCCCCCCEEEEEECCCE
TYLAGDIVYHDEKFKQDYTKYINIWGADHHGYIARVKASLEFLGYDSNKLEVLLAQMVRL
EEEEEEEEECCHHHHHHHHHHEEEECCCCCCCCEEEEEHHHEECCCCCHHHHHHHHHHHH
LKDNEPYKMSKRAGNFILIKDVVDDVGKDALRFIFLSKRLDTHLEFDVNTLKKQDSSNPI
HCCCCCCCHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHCCCCCCCE
YYIHYANSRIHTMLEKSPFSKEEVLQTPLTNLNAEEKYLLFSALSLPKAIESSFEEYGLQ
EEEEECCCHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHH
KMCEYAKTLASEFHRFYNAGKILDTPKAKELLKICLIVSLSLSNAFKLLGIEIKTKISAR
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEEEEECCCC
D
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA