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Identifier: 15644840

GI number: 15644840

Start: 219098

End: 220249

Strand: Reverse

Name: Not Available

Synonym: HP0212

Alternate gene names: 15644840

Gene position: 220249-219098 (Counterclockwise)

Preceding gene: 15644841

Following gene: 15644839

Centisome position: 13.21

GC content: 41.06

Gene sequence:

>1152_bases
ATGGACGCTTTAGAAATCACCCAAAAGCTCATCAGCTACCCCACCATTACGCCCAAAGAATGCGGTATTTTTGAATACAT
TAAATCGCTTTTTCCTCATTTTAAAACTCTAGAGTGTGGAGAAAATGGCGTGAAAAACCTTTTTTTATACCGCATTTTTA
ACCCCCCCAAAGACCATGCAGAAGAAAAGCATGCAAAAGAGAATACCAAGCCCTTGCATTTTTGCTTTGCAGGGCATATT
GATGTCGTGCCTCCTGGAAATCATTGGCAAAGCGATCCTTTTAAACCCGTTATTAAAGAGGGGTTTTTATACGGCCGTGG
GGCGCAAGACATGAAAGGAGGCGTGGGGGCGTTTTTGAGCGCGAGTTTAAATTTTAACCCTAAAACCCCTTTTTTGCTTT
CTATTTTACTCACAAGCGATGAAGAAGGGCCAGGGATTTTTGGCACTAGGCTTATGTTAGAAAAACTCAAAGAAAAAGAT
TTGCTGCCTCATATGGCGATTGTGGCTGAACCCACTTGCGAAAAAGTCTTAGGCGATAGCATCAAAATTGGCCGAAGAGG
CTCCATTAATGGCAAACTCATTTTAAAAGGCGTTCAAGGGCATGTGGCTTACCCGCAAAAATGCCAAAACCCTATTGATA
CGCTCGCTTCGGTTTTGCCTCTCATTTCAGGAGTTAATTTAGACAATGGCGATGAATATTTTGACCCTTCAAAATTAGTC
ATCACCAACTTGCATGCAGGGTTAGGAGCGAATAATATTACCCCAGCAAGCGTAGAAATCATCTTTAATGCACGCCATTC
TTTAAAAACCACCAAAGAGAGTTTGAAAGAATATTTAGAAAAAGTTTTGAAAGATTTGCCTTATACTTTAGAATTAGAAT
CAAGCAGTTCGCCTTTCATCACGGCTTCTCATTCAAAGCTTACCAGCGTTTTAAAAGAAAATATTTTAAAAACATGCCAC
ACCACCCCCCTTTTAAACACCAAAGGCGGCACGAGCGATGCGCGATTTTTTAGCGCTCATGGTATAGAAGTGGTGGAGTT
TGGCGTTATTAATGACAGGATCCATGCCATTGATGAAAGGGTGAGCTTGAAAGAATTAGAGCTTTTAGAAAAAGTGTTTT
TGGGGGTTTTAGAGGGCTTGAGTGAGGCATAA

Upstream 100 bases:

>100_bases
AAGCCTTTTTGAAGCCTCAGAAATCAGCGGGATCACCCCAGCGAATTTAGACGTTTTGCATTTGTATATTCATTTGCGGA
AAAACTCTTAAAGGATTGGC

Downstream 100 bases:

>100_bases
AATAAACAAACATTAAGTAAGGCTTATCAATATTTGATTACAATTATAAGGGTTACATTTTTTTAATAGGAGATATACCA
TGCTAGGAAACGTTAAAAAA

Product: succinyl-diaminopimelate desuccinylase

Products: NA

Alternate protein names: SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MDALEITQKLISYPTITPKECGIFEYIKSLFPHFKTLECGENGVKNLFLYRIFNPPKDHAEEKHAKENTKPLHFCFAGHI
DVVPPGNHWQSDPFKPVIKEGFLYGRGAQDMKGGVGAFLSASLNFNPKTPFLLSILLTSDEEGPGIFGTRLMLEKLKEKD
LLPHMAIVAEPTCEKVLGDSIKIGRRGSINGKLILKGVQGHVAYPQKCQNPIDTLASVLPLISGVNLDNGDEYFDPSKLV
ITNLHAGLGANNITPASVEIIFNARHSLKTTKESLKEYLEKVLKDLPYTLELESSSSPFITASHSKLTSVLKENILKTCH
TTPLLNTKGGTSDARFFSAHGIEVVEFGVINDRIHAIDERVSLKELELLEKVFLGVLEGLSEA

Sequences:

>Translated_383_residues
MDALEITQKLISYPTITPKECGIFEYIKSLFPHFKTLECGENGVKNLFLYRIFNPPKDHAEEKHAKENTKPLHFCFAGHI
DVVPPGNHWQSDPFKPVIKEGFLYGRGAQDMKGGVGAFLSASLNFNPKTPFLLSILLTSDEEGPGIFGTRLMLEKLKEKD
LLPHMAIVAEPTCEKVLGDSIKIGRRGSINGKLILKGVQGHVAYPQKCQNPIDTLASVLPLISGVNLDNGDEYFDPSKLV
ITNLHAGLGANNITPASVEIIFNARHSLKTTKESLKEYLEKVLKDLPYTLELESSSSPFITASHSKLTSVLKENILKTCH
TTPLLNTKGGTSDARFFSAHGIEVVEFGVINDRIHAIDERVSLKELELLEKVFLGVLEGLSEA
>Mature_383_residues
MDALEITQKLISYPTITPKECGIFEYIKSLFPHFKTLECGENGVKNLFLYRIFNPPKDHAEEKHAKENTKPLHFCFAGHI
DVVPPGNHWQSDPFKPVIKEGFLYGRGAQDMKGGVGAFLSASLNFNPKTPFLLSILLTSDEEGPGIFGTRLMLEKLKEKD
LLPHMAIVAEPTCEKVLGDSIKIGRRGSINGKLILKGVQGHVAYPQKCQNPIDTLASVLPLISGVNLDNGDEYFDPSKLV
ITNLHAGLGANNITPASVEIIFNARHSLKTTKESLKEYLEKVLKDLPYTLELESSSSPFITASHSKLTSVLKENILKTCH
TTPLLNTKGGTSDARFFSAHGIEVVEFGVINDRIHAIDERVSLKELELLEKVFLGVLEGLSEA

Specific function: Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bact

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. DapE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788816, Length=388, Percent_Identity=34.2783505154639, Blast_Score=228, Evalue=7e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR005941
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.18 [H]

Molecular weight: Translated: 42243; Mature: 42243

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDALEITQKLISYPTITPKECGIFEYIKSLFPHFKTLECGENGVKNLFLYRIFNPPKDHA
CCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEHHCCCCCCCEEEEEEECCCCHHHH
EEKHAKENTKPLHFCFAGHIDVVPPGNHWQSDPFKPVIKEGFLYGRGAQDMKGGVGAFLS
HHHHHHCCCCCEEEEEECCEEECCCCCCCCCCCCCHHHHCCCEECCCCHHHCCCCCHHEE
ASLNFNPKTPFLLSILLTSDEEGPGIFGTRLMLEKLKEKDLLPHMAIVAEPTCEKVLGDS
EECCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHEEECCHHHHHCCCC
IKIGRRGSINGKLILKGVQGHVAYPQKCQNPIDTLASVLPLISGVNLDNGDEYFDPSKLV
EECCCCCCCCCEEEEEECCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
ITNLHAGLGANNITPASVEIIFNARHSLKTTKESLKEYLEKVLKDLPYTLELESSSSPFI
EEEHHCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEE
TASHSKLTSVLKENILKTCHTTPLLNTKGGTSDARFFSAHGIEVVEFGVINDRIHAIDER
EECHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCEEEEEECHHHHHHHHHHH
VSLKELELLEKVFLGVLEGLSEA
HHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDALEITQKLISYPTITPKECGIFEYIKSLFPHFKTLECGENGVKNLFLYRIFNPPKDHA
CCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEHHCCCCCCCEEEEEEECCCCHHHH
EEKHAKENTKPLHFCFAGHIDVVPPGNHWQSDPFKPVIKEGFLYGRGAQDMKGGVGAFLS
HHHHHHCCCCCEEEEEECCEEECCCCCCCCCCCCCHHHHCCCEECCCCHHHCCCCCHHEE
ASLNFNPKTPFLLSILLTSDEEGPGIFGTRLMLEKLKEKDLLPHMAIVAEPTCEKVLGDS
EECCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHEEECCHHHHHCCCC
IKIGRRGSINGKLILKGVQGHVAYPQKCQNPIDTLASVLPLISGVNLDNGDEYFDPSKLV
EECCCCCCCCCEEEEEECCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
ITNLHAGLGANNITPASVEIIFNARHSLKTTKESLKEYLEKVLKDLPYTLELESSSSPFI
EEEHHCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEE
TASHSKLTSVLKENILKTCHTTPLLNTKGGTSDARFFSAHGIEVVEFGVINDRIHAIDER
EECHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCEEEEEECHHHHHHHHHHH
VSLKELELLEKVFLGVLEGLSEA
HHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA