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Identifier: 15644809

GI number: 15644809

Start: 186462

End: 187739

Strand: Reverse

Name: Not Available

Synonym: HP0180

Alternate gene names: 15644809

Gene position: 187739-186462 (Counterclockwise)

Preceding gene: 15644815

Following gene: 15644808

Centisome position: 11.26

GC content: 36.85

Gene sequence:

>1278_bases
ATGCGTCTTCTTCTGTTCAATCAAAACGCTTTTTTATTAGCGTGCATGTTTGTTTCAAGCGTGTATGTGAACGCTGTCTT
AGACGCTTATGCAATTGAAAACCCCTATATTTCTATCACACTCACAAGCCTATTAGCCCCTTTAAGCATGCTAGCGTTTT
TAAAAACCCCTAGAAATAGTGCTTTTGCTTTGGGGTTTTTTGTGGGGGCGTTATTGTTTTATTGGTGCGCTTTAAGCTTT
CGCTACTCGGATTTCACTTATTTATTGCCCTTAATCATTGTTTTAATAGCGTTAGTTTATGGGGTTTTATTTTATTTGTT
GCTCTATTTTGAAAACCCCTATTTCAGGCTTTTGAGTTTTTTAGGCTCTAGTTTTATCCACCCCTTTGGATTTGATTGGT
TAGTCCCAGATAGCTTTTTTTCTTATAGCGTGTTTAGAGTGGATAAATTATCGCTAGGGCTTGTTTTTTTGGCTTGCATT
TTTTTGAGCACTAAACCATTGAAAAAATATAGGATCATAGGGGTTTTATTGTTACTTGGCGCGTTGGATTTTAATGGTTT
CAAAACAAGCGATTTAAAAAAGGTTGGAAATATTGAATTAGTCTCTACAAAAACGCCCCAAGATTTGAAATTTGACTCAA
GTTACCTTAATGATATTGAAAACAACATTCTTAAAGAAATCAAGCTCGCTCAAAGCAAGCAAAAAACCTTGATTGTTTTT
CCAGAAACCGCCTACCCCATCGCTTTAGAAAACTCCCCCTTTAAAGCGAAGCTAGAAGATTTAAGCGATAATATTGCTAT
TTTAATAGGGACATTACGGACTCAAGGCTATAATCTTTATAACAGCTCGTTTTTATTTTCTAAAGAAAGCGTTCAGATCG
CTGATAAAGTAATTTTAGCCCCCTTTGGCGAGACCATGCCTTTACCGGAATTTCTTCAAAAACCCCTTGAAAAGCTCTTT
TTTGGCGAGAGCACTTATTTATACCGCAATGCTCCTCATTTCAGCGATTTTACATTAGACGATTTTACTTTTCGCCCCCT
GATTTGCTATGAAGGCACTTCCAAACCCGCTTATTCAAACAGCCCTTCAAAAATTTTTATCGTGATGAGCAATAACGCAT
GGTTTAGCCCAAGCATTGAACCCACCTTACAAAGAACGCTTTTAAAATACTACGCAAGGCGTTATGATAAGATCATCTTG
CACAGCGCGAACTTTTCAACTTCTTACATCTTAAGCCCTAGTTTATTAGGCGATATTCTTTTTAGGAAACGATCATGA

Upstream 100 bases:

>100_bases
AACTTAAAAAAAACTACCCTTAAAAAAATCAATCTAAAATTCTTAAATTAAAATATAGCTATAATACACTAAAACAATCT
CAAGGTTTCAAAATTTAGCC

Downstream 100 bases:

>100_bases
TTAAAGCGATTAATATTTCTCATGCTTTTGAAAAGCCTCTTTATAATGGCGTGAATTTGCACATCAAGCCCAAAGAAAGC
CTAGCGATTTTAGGCGTGAG

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase [H]

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MRLLLFNQNAFLLACMFVSSVYVNAVLDAYAIENPYISITLTSLLAPLSMLAFLKTPRNSAFALGFFVGALLFYWCALSF
RYSDFTYLLPLIIVLIALVYGVLFYLLLYFENPYFRLLSFLGSSFIHPFGFDWLVPDSFFSYSVFRVDKLSLGLVFLACI
FLSTKPLKKYRIIGVLLLLGALDFNGFKTSDLKKVGNIELVSTKTPQDLKFDSSYLNDIENNILKEIKLAQSKQKTLIVF
PETAYPIALENSPFKAKLEDLSDNIAILIGTLRTQGYNLYNSSFLFSKESVQIADKVILAPFGETMPLPEFLQKPLEKLF
FGESTYLYRNAPHFSDFTLDDFTFRPLICYEGTSKPAYSNSPSKIFIVMSNNAWFSPSIEPTLQRTLLKYYARRYDKIIL
HSANFSTSYILSPSLLGDILFRKRS

Sequences:

>Translated_425_residues
MRLLLFNQNAFLLACMFVSSVYVNAVLDAYAIENPYISITLTSLLAPLSMLAFLKTPRNSAFALGFFVGALLFYWCALSF
RYSDFTYLLPLIIVLIALVYGVLFYLLLYFENPYFRLLSFLGSSFIHPFGFDWLVPDSFFSYSVFRVDKLSLGLVFLACI
FLSTKPLKKYRIIGVLLLLGALDFNGFKTSDLKKVGNIELVSTKTPQDLKFDSSYLNDIENNILKEIKLAQSKQKTLIVF
PETAYPIALENSPFKAKLEDLSDNIAILIGTLRTQGYNLYNSSFLFSKESVQIADKVILAPFGETMPLPEFLQKPLEKLF
FGESTYLYRNAPHFSDFTLDDFTFRPLICYEGTSKPAYSNSPSKIFIVMSNNAWFSPSIEPTLQRTLLKYYARRYDKIIL
HSANFSTSYILSPSLLGDILFRKRS
>Mature_425_residues
MRLLLFNQNAFLLACMFVSSVYVNAVLDAYAIENPYISITLTSLLAPLSMLAFLKTPRNSAFALGFFVGALLFYWCALSF
RYSDFTYLLPLIIVLIALVYGVLFYLLLYFENPYFRLLSFLGSSFIHPFGFDWLVPDSFFSYSVFRVDKLSLGLVFLACI
FLSTKPLKKYRIIGVLLLLGALDFNGFKTSDLKKVGNIELVSTKTPQDLKFDSSYLNDIENNILKEIKLAQSKQKTLIVF
PETAYPIALENSPFKAKLEDLSDNIAILIGTLRTQGYNLYNSSFLFSKESVQIADKVILAPFGETMPLPEFLQKPLEKLF
FGESTYLYRNAPHFSDFTLDDFTFRPLICYEGTSKPAYSNSPSKIFIVMSNNAWFSPSIEPTLQRTLLKYYARRYDKIIL
HSANFSTSYILSPSLLGDILFRKRS

Specific function: Transfers the fatty acyl group on membrane lipoproteins [H]

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004563
- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 48474; Mature: 48474

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLLFNQNAFLLACMFVSSVYVNAVLDAYAIENPYISITLTSLLAPLSMLAFLKTPRNS
CEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCC
AFALGFFVGALLFYWCALSFRYSDFTYLLPLIIVLIALVYGVLFYLLLYFENPYFRLLSF
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LGSSFIHPFGFDWLVPDSFFSYSVFRVDKLSLGLVFLACIFLSTKPLKKYRIIGVLLLLG
HHHHCCCCCCCCCCCCCHHHCEEEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ALDFNGFKTSDLKKVGNIELVSTKTPQDLKFDSSYLNDIENNILKEIKLAQSKQKTLIVF
HCCCCCCCCHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEE
PETAYPIALENSPFKAKLEDLSDNIAILIGTLRTQGYNLYNSSFLFSKESVQIADKVILA
CCCCCEEEECCCCCHHHHHHCCCCEEEEEEEHHCCCCCEECCCEEECCCCHHHHHEEEEE
PFGETMPLPEFLQKPLEKLFFGESTYLYRNAPHFSDFTLDDFTFRPLICYEGTSKPAYSN
CCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCC
SPSKIFIVMSNNAWFSPSIEPTLQRTLLKYYARRYDKIILHSANFSTSYILSPSLLGDIL
CCCEEEEEEECCCEECCCCCHHHHHHHHHHHHHHHCEEEEEECCCCCEEEECHHHHHHHH
FRKRS
HHCCC
>Mature Secondary Structure
MRLLLFNQNAFLLACMFVSSVYVNAVLDAYAIENPYISITLTSLLAPLSMLAFLKTPRNS
CEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCC
AFALGFFVGALLFYWCALSFRYSDFTYLLPLIIVLIALVYGVLFYLLLYFENPYFRLLSF
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LGSSFIHPFGFDWLVPDSFFSYSVFRVDKLSLGLVFLACIFLSTKPLKKYRIIGVLLLLG
HHHHCCCCCCCCCCCCCHHHCEEEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ALDFNGFKTSDLKKVGNIELVSTKTPQDLKFDSSYLNDIENNILKEIKLAQSKQKTLIVF
HCCCCCCCCHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEE
PETAYPIALENSPFKAKLEDLSDNIAILIGTLRTQGYNLYNSSFLFSKESVQIADKVILA
CCCCCEEEECCCCCHHHHHHCCCCEEEEEEEHHCCCCCEECCCEEECCCCHHHHHEEEEE
PFGETMPLPEFLQKPLEKLFFGESTYLYRNAPHFSDFTLDDFTFRPLICYEGTSKPAYSN
CCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCC
SPSKIFIVMSNNAWFSPSIEPTLQRTLLKYYARRYDKIILHSANFSTSYILSPSLLGDIL
CCCEEEEEEECCCEECCCCCHHHHHHHHHHHHHHHCEEEEEECCCCCEEEECHHHHHHHH
FRKRS
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]